QIIME 2

ANCOM Volcano Plot

ANCOM statistical results

W
Streptococcus mutans (SP84) 1804
Neisseria flavescens|subflava (SP56) 1802
Rothia dentocariosa (SP153) 1802
Rothia mucilaginosa (SP38) 1801
Porphyromonas gingivalis (SP267) 1799
Haemophilus parainfluenzae (SP55) 1797
Actinomyces odontolyticus (SP47) 1796
Prevotella nigrescens (SP17) 1795
Actinomyces odontolyticus_nov_97.510% (SPN1027) 1776
Leptotrichia sp._oral_taxon_218 (SP166) 1765
Actinomyces odontolyticus_nov_97.510% (SPN277) 1754
Actinomyces graevenitzii (SP21) 1754
Actinomyces odontolyticus_nov_96.074% (SPN854) 1746
Actinomyces odontolyticus_nov_97.510% (SPN293) 1740
Prevotella nigrescens_nov_96.755% (SPN283) 1740
Actinomyces odontolyticus_nov_97.718% (SPN296) 1725
Actinomyces meyeri (SP180) 1719
Rothia dentocariosa_nov_97.458% (SPN307) 1719
Leptotrichia sp._oral_taxon_417 (SP48) 1717
Fusobacterium nucleatum_subsp._nucleatum (SP193) 1716
Veillonella parvula_group_nov_96.477% (SPN747) 1702
Actinomyces sp._oral_taxon_180 (SP73) 1701
Prevotella nigrescens_nov_96.566% (SPN389) 1697
Isoptericola dokdonensis_nov_90.717% (SPN1049) 1692
Actinomyces sp._oral_taxon_180_nov_97.942% (SPN509) 1681
Prevotella aurantiaca (SP309) 1680
Selenomonas sp._oral_taxon_149 (SP23) 1677
Prevotella nigrescens_nov_97.976% (SPN414) 1674
Rothia dentocariosa_nov_97.881% (SPN402) 1670
Actinomyces multispecies_spp32_2 (SPP32) 1665
SR1_[G-1] sp._oral_taxon_875 (SP277) 1658
Lachnospiraceae_[G-2] sp._oral_taxon_096 (SP201) 1658
Neisseria flava (SP235) 1648
Streptococcus salivarius_nov_94.200% (SPN285) 1645
Neisseria flavescens|subflava_nov_97.967% (SPN308) 1643
Corynebacterium durum (SP213) 1640
Haemophilus sputorum (SP188) 1639
Prevotella intermedia (SP79) 1638
Selenomonas sp._oral_taxon_136 (SP9) 1625
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Percentile abundances of features by group

Percentile 0.0 25.0 50.0 75.0 100.0 0.0 25.0 50.0 75.0 100.0 0.0 25.0 50.0 75.0 100.0 0.0 25.0 50.0 75.0 100.0 0.0 25.0 50.0 75.0 100.0 0.0 25.0 50.0 75.0 100.0 0.0 25.0 50.0 75.0 100.0
Group Caries_inoculum Caries_inoculum Caries_inoculum Caries_inoculum Caries_inoculum Caries_saliva Caries_saliva Caries_saliva Caries_saliva Caries_saliva Healthy_inoculum Healthy_inoculum Healthy_inoculum Healthy_inoculum Healthy_inoculum Healthy_saliva Healthy_saliva Healthy_saliva Healthy_saliva Healthy_saliva Healthy_saliva_plus_S_mutans Healthy_saliva_plus_S_mutans Healthy_saliva_plus_S_mutans Healthy_saliva_plus_S_mutans Healthy_saliva_plus_S_mutans Mock_community Mock_community Mock_community Mock_community Mock_community Negative_control Negative_control Negative_control Negative_control Negative_control
Streptococcus mutans (SP84) 1.0 2.25 3.5 4.75 6.0 4.0 6.00 9.5 14.00 31.0 3.0 4.25 5.5 6.75 8.0 2.0 3.25 6.0 13.25 38.0 2.0 16.00 64.0 233.75 2035.0 383.0 388.50 394.0 399.50 405.0 47.0 169.25 257.0 311.75 653.0
Neisseria flavescens|subflava (SP56) 2079.0 2180.25 2281.5 2382.75 2484.0 4.0 7.25 14.0 21.00 43.0 5478.0 5803.25 6128.5 6453.75 6779.0 1.0 5.00 14.0 20.00 57.0 2.0 15.00 21.5 31.75 55.0 2028.0 2063.00 2098.0 2133.00 2168.0 16.0 25.25 32.5 33.75 37.0
Rothia dentocariosa (SP153) 3.0 11.75 20.5 29.25 38.0 1.0 1.00 1.0 2.00 18.0 126.0 128.00 130.0 132.00 134.0 1.0 1.00 1.0 2.00 22.0 1.0 1.00 1.5 9.75 20.0 3152.0 3305.50 3459.0 3612.50 3766.0 1.0 1.00 1.5 5.75 11.0
Rothia mucilaginosa (SP38) 2085.0 2208.75 2332.5 2456.25 2580.0 1.0 1.00 2.0 3.75 10.0 466.0 475.00 484.0 493.00 502.0 1.0 2.00 2.0 3.00 8.0 1.0 1.25 2.5 4.00 9.0 1.0 1.25 1.5 1.75 2.0 1.0 2.25 3.5 4.00 6.0
Porphyromonas gingivalis (SP267) 18.0 18.75 19.5 20.25 21.0 1.0 1.00 1.0 1.00 2.0 1.0 1.25 1.5 1.75 2.0 1.0 1.00 1.0 1.00 2.0 1.0 1.00 1.0 1.00 2.0 55.0 58.25 61.5 64.75 68.0 1.0 1.00 1.0 1.00 1.0
Haemophilus parainfluenzae (SP55) 540.0 576.00 612.0 648.00 684.0 1.0 3.75 8.0 15.75 30.0 779.0 804.75 830.5 856.25 882.0 1.0 3.50 8.5 20.00 75.0 1.0 11.25 16.5 20.00 110.0 286.0 301.25 316.5 331.75 347.0 10.0 14.25 16.0 36.50 141.0
Actinomyces odontolyticus (SP47) 1259.0 1309.75 1360.5 1411.25 1462.0 7.0 38.00 59.5 79.25 209.0 1972.0 2063.25 2154.5 2245.75 2337.0 1.0 10.25 47.0 123.50 494.0 16.0 24.75 121.0 178.50 348.0 15643.0 16671.50 17700.0 18728.50 19757.0 35.0 86.50 150.5 192.75 280.0
Prevotella nigrescens (SP17) 14.0 15.25 16.5 17.75 19.0 1.0 1.00 2.0 10.00 94.0 39.0 41.00 43.0 45.00 47.0 1.0 1.00 1.0 2.75 104.0 1.0 1.00 2.5 52.75 103.0 18600.0 21131.25 23662.5 26193.75 28725.0 1.0 1.25 2.5 36.75 52.0
Actinomyces odontolyticus_nov_97.510% (SPN1027) 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 1.0 1.50 2.0 2.50 3.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 53.0 61.00 69.0 77.00 85.0 1.0 1.00 1.0 1.00 1.0
Leptotrichia sp._oral_taxon_218 (SP166) 231.0 241.00 251.0 261.00 271.0 1.0 1.00 1.0 2.00 6.0 5.0 5.50 6.0 6.50 7.0 1.0 1.00 1.0 1.00 2.0 1.0 1.00 1.0 1.75 4.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0
Actinomyces odontolyticus_nov_97.510% (SPN277) 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 3.0 3.50 4.0 4.50 5.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 2.0 28.0 32.25 36.5 40.75 45.0 1.0 1.00 1.0 1.00 1.0
Actinomyces graevenitzii (SP21) 145.0 145.50 146.0 146.50 147.0 1.0 1.00 2.0 5.00 8.0 157.0 159.25 161.5 163.75 166.0 1.0 1.00 1.5 6.25 15.0 1.0 2.25 4.0 5.00 19.0 1.0 1.50 2.0 2.50 3.0 5.0 6.00 6.5 18.25 29.0
Actinomyces odontolyticus_nov_96.074% (SPN854) 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 2.0 2.00 2.0 2.00 2.0 1.0 1.00 1.0 1.00 3.0 1.0 1.00 1.0 1.00 1.0 32.0 37.25 42.5 47.75 53.0 1.0 1.00 1.0 1.00 1.0
Actinomyces odontolyticus_nov_97.510% (SPN293) 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 1.0 1.50 2.0 2.50 3.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 28.0 30.25 32.5 34.75 37.0 1.0 1.00 1.0 1.00 1.0
Prevotella nigrescens_nov_96.755% (SPN283) 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 19.0 28.00 37.0 46.00 55.0 1.0 1.00 1.0 1.00 1.0
Actinomyces odontolyticus_nov_97.718% (SPN296) 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 2.0 2.0 2.50 3.0 3.50 4.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 18.0 23.75 29.5 35.25 41.0 1.0 1.00 1.0 1.00 1.0
Actinomyces meyeri (SP180) 27.0 30.75 34.5 38.25 42.0 1.0 1.00 1.0 1.00 2.0 34.0 44.00 54.0 64.00 74.0 1.0 1.00 1.0 1.00 5.0 1.0 1.00 1.0 1.75 3.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.5 2.75 4.0
Rothia dentocariosa_nov_97.458% (SPN307) 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 1.0 2.00 3.0 4.00 5.0 1.0 1.00 1.0 1.00 2.0 1.0 1.00 1.0 1.00 2.0 26.0 26.50 27.0 27.50 28.0 1.0 1.00 1.0 1.00 1.0
Leptotrichia sp._oral_taxon_417 (SP48) 355.0 377.75 400.5 423.25 446.0 1.0 1.00 1.5 3.75 9.0 64.0 65.50 67.0 68.50 70.0 1.0 1.00 1.0 2.75 10.0 1.0 1.00 2.0 3.00 44.0 1.0 1.00 1.0 1.00 1.0 1.0 1.25 3.0 7.75 81.0
Fusobacterium nucleatum_subsp._nucleatum (SP193) 1.0 1.00 1.0 1.00 1.0 1.0 1.00 2.0 3.00 8.0 1.0 1.25 1.5 1.75 2.0 1.0 1.00 1.0 2.00 127.0 1.0 1.00 1.5 3.75 6.0 110.0 126.75 143.5 160.25 177.0 1.0 2.00 3.0 7.75 15.0
Veillonella parvula_group_nov_96.477% (SPN747) 1.0 1.75 2.5 3.25 4.0 1.0 1.00 1.0 1.00 2.0 12.0 12.50 13.0 13.50 14.0 1.0 1.00 1.0 1.75 8.0 1.0 1.00 1.0 1.00 5.0 17.0 17.75 18.5 19.25 20.0 1.0 1.00 1.0 1.75 5.0
Actinomyces sp._oral_taxon_180 (SP73) 539.0 565.25 591.5 617.75 644.0 1.0 2.75 6.5 10.75 32.0 272.0 295.50 319.0 342.50 366.0 1.0 2.25 5.0 9.00 25.0 1.0 3.25 7.5 13.75 45.0 1.0 1.50 2.0 2.50 3.0 1.0 4.25 10.5 17.50 30.0
Prevotella nigrescens_nov_96.566% (SPN389) 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 13.0 14.75 16.5 18.25 20.0 1.0 1.00 1.0 1.00 1.0
Isoptericola dokdonensis_nov_90.717% (SPN1049) 18.0 42.75 67.5 92.25 117.0 1.0 1.00 1.0 1.00 1.0 1.0 1.25 1.5 1.75 2.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0
Actinomyces sp._oral_taxon_180_nov_97.942% (SPN509) 196.0 207.75 219.5 231.25 243.0 1.0 1.00 3.5 6.00 24.0 7.0 7.75 8.5 9.25 10.0 1.0 1.00 1.0 1.00 2.0 1.0 1.25 2.0 3.75 32.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.5 2.00 3.0
Prevotella aurantiaca (SP309) 33.0 38.00 43.0 48.00 53.0 1.0 1.00 1.0 2.00 6.0 39.0 42.75 46.5 50.25 54.0 1.0 1.00 1.0 2.00 5.0 1.0 1.00 2.0 2.75 4.0 1.0 1.00 1.0 1.00 1.0 1.0 2.00 2.0 2.75 5.0
Selenomonas sp._oral_taxon_149 (SP23) 44.0 53.00 62.0 71.00 80.0 68.0 237.25 3031.0 5719.50 10897.0 8.0 10.50 13.0 15.50 18.0 27.0 52.00 102.5 225.75 392.0 28.0 133.00 254.5 3211.75 7514.0 14.0 24.25 34.5 44.75 55.0 92.0 117.50 182.0 271.25 400.0
Prevotella nigrescens_nov_97.976% (SPN414) 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 2.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 12.0 13.25 14.5 15.75 17.0 1.0 1.00 1.0 1.00 1.0
Rothia dentocariosa_nov_97.881% (SPN402) 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 1.0 1.50 2.0 2.50 3.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 2.0 11.0 12.75 14.5 16.25 18.0 1.0 1.00 1.0 1.00 1.0
Actinomyces multispecies_spp32_2 (SPP32) 35.0 39.75 44.5 49.25 54.0 1.0 1.00 1.5 3.00 5.0 64.0 69.50 75.0 80.50 86.0 1.0 1.00 1.0 3.00 6.0 1.0 1.00 2.5 4.00 7.0 1.0 1.25 1.5 1.75 2.0 1.0 2.25 6.5 10.75 18.0
SR1_[G-1] sp._oral_taxon_875 (SP277) 30.0 32.50 35.0 37.50 40.0 1.0 1.00 1.0 1.75 4.0 11.0 13.50 16.0 18.50 21.0 1.0 1.00 1.0 1.00 2.0 1.0 1.00 1.0 2.00 5.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 2.0
Lachnospiraceae_[G-2] sp._oral_taxon_096 (SP201) 70.0 76.75 83.5 90.25 97.0 1.0 1.00 2.0 3.75 13.0 2.0 2.50 3.0 3.50 4.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.75 9.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0
Neisseria flava (SP235) 10.0 12.00 14.0 16.00 18.0 1.0 1.00 1.0 1.00 2.0 26.0 28.50 31.0 33.50 36.0 1.0 1.00 1.0 2.00 4.0 1.0 1.00 1.0 1.00 7.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.75 4.0
Streptococcus salivarius_nov_94.200% (SPN285) 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 2.0 24.0 27.75 31.5 35.25 39.0 1.0 1.00 1.0 1.00 2.0 1.0 1.00 1.0 2.00 3.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 2.0
Neisseria flavescens|subflava_nov_97.967% (SPN308) 1.0 2.00 3.0 4.00 5.0 1.0 1.00 1.0 1.00 1.0 22.0 25.00 28.0 31.00 34.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0
Corynebacterium durum (SP213) 7.0 7.25 7.5 7.75 8.0 1.0 1.00 1.0 1.00 2.0 21.0 23.50 26.0 28.50 31.0 1.0 1.00 1.0 1.00 2.0 1.0 1.00 1.0 1.00 2.0 1.0 1.25 1.5 1.75 2.0 1.0 1.00 1.5 2.00 4.0
Haemophilus sputorum (SP188) 22.0 24.75 27.5 30.25 33.0 1.0 1.00 1.0 2.00 6.0 22.0 24.00 26.0 28.00 30.0 1.0 1.00 1.5 2.00 8.0 1.0 1.00 1.0 2.00 5.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 2.0
Prevotella intermedia (SP79) 22.0 24.75 27.5 30.25 33.0 1.0 1.00 1.0 2.50 5.0 11.0 12.25 13.5 14.75 16.0 1.0 1.00 1.0 1.00 3.0 1.0 1.00 1.0 1.00 2.0 1.0 1.00 1.0 1.00 1.0 1.0 1.00 1.0 1.00 1.0
Selenomonas sp._oral_taxon_136 (SP9) 81.0 86.25 91.5 96.75 102.0 78.0 242.75 3872.0 7994.75 18824.0 20.0 24.50 29.0 33.50 38.0 37.0 94.00 129.0 272.25 394.0 69.0 127.00 288.0 3770.25 13703.0 28.0 35.75 43.5 51.25 59.0 83.0 105.75 164.5 264.50 492.0
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