K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Erysipelotrichaceae.G_Erysipelatoclostridium.S_ramosum 0.0 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Mammaliicoccus.S_lentus 2.7577947076735274 WT_Control 3.6954838650122497 0.018602929901135698 K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Corynebacteriales.F_Corynebacteriaceae.G_Corynebacterium.S_lowii 5.212193655651761 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus.S_faecalis 5.357372609887252 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Weissella.S_paramesenteroides 2.5198860871787003 WT_Control 3.26653701932844 0.018602929901135698 K_Bacteria.P_Verrucomicrobia.C_Verrucomicrobiae.O_Verrucomicrobiales.F_Akkermansiaceae.G_Akkermansia.S_muciniphila 3.206793207693054 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Erwiniaceae.G_Pantoea.S_conspicua 3.6544795354419675 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Klebsiella.S_variicola 0.0 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Erwiniaceae.G_Pantoea.S_dispersa 0.0 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Staphylococcus.S_ureilyticus 3.155985009382931 WT_Control 3.615328396433999 0.0070583320485280935 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Lactobacillus.S_johnsonii 5.269361545044578 WT_Control 4.952237614096819 0.009023438818080319 K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Mammaliicoccus.S_sciuri 3.9987756407768873 - K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Corynebacteriales.F_Corynebacteriaceae.G_Corynebacterium.S_tuberculostearicum 2.173213103298496 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Erwiniaceae.G_Pantoea.S_brenneri 3.28485259414625 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Staphylococcus.S_capitis 0.0 - K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Erysipelotrichaceae.G_Dubosiella.S_newyorkensis 3.958316082674989 WT_Control 3.7694727133292423 0.008207736107348857 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Enterobacter.S_mori 5.1177651593741045 - K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Peptostreptococcaceae.G_Romboutsia.S_timonensis 3.313791049105451 WT_Control 3.2263096975008065 0.0070583320485280935 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Klebsiella.S_pneumoniae 0.0 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Carnobacteriaceae.G_Atopostipes.S_sp__MOT_201 3.4485825779174553 WT_Control 3.163736100828 0.018602929901135698 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Erwiniaceae.G_Mixta.S_calida 4.802837435175647 - K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Erysipelotrichaceae.G_Faecalibaculum.S_rodentium 2.5471979034961896 - K_Bacteria.P_Bacteroidetes.C_Bacteroidia.O_Bacteroidales.F_Muribaculaceae.G_Muribaculaceae__G_2_.S_bacterium_MOT_104_nov_90_802 4.185558591881434 WT_Control 3.9716033175682797 0.008207736107348857 K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Planococcaceae.G_Sporosarcina.S_siberiensis_nov_97_892 0.0 - K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Turicibacteraceae.G_Turicibacter.S_sanguinis_nov_96_262 2.4250110511616256 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Weissella.S_paramesenteroides_nov_94_614 0.9601564259328422 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus.S_faecalis_nov_94_614 1.032140444664131 - K_Bacteria.P_Bacteroidetes.C_Bacteroidia.O_Bacteroidales.F_Muribaculaceae.G_Muribaculaceae__G_2_.S_bacterium_MOT_104_nov_89_810 1.6099895720252582 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus.S_faecalis_nov_97_424 0.0 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus.S_faecalis_nov_94_626 4.172594882581851 WT_Control 3.846963615355831 0.027802962434649126 K_Bacteria.P_Cyanobacteria.C_Gloeobacteria.O_Gloeobacterales.F_Gloeobacteraceae.G_Gloeobacter.S_kilaueensis_nov_81_638 0.0 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Lactobacillus.S_johnsonii_nov_94_626 4.095191223313304 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus.S_multispecies_spp12_2 5.4856652942788795 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_multifamily.G_multigenus.S_multispecies_spp143_4 4.913293711156986 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Limosilactobacillus.S_multispecies_spp16_2 3.851607195955884 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_multigenus.S_multispecies_spp21_6 0.0 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Enterobacter.S_multispecies_spp22_4 5.0018074576996865 - K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Clostridiaceae.G_Clostridium.S_multispecies_spp28_2 2.3389026358734144 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus.S_multispecies_spp29_5 0.0 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Kluyvera.S_multispecies_spp39_2 0.0 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_multigenus.S_multispecies_spp41_2 0.0 - K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Lachnospiraceae.G_Blautia.S_multispecies_spp48_3 2.5199090970627784 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus.S_multispecies_spp57_3 3.4580507794294744 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Staphylococcus.S_multispecies_spp59_3 0.0 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Klebsiella.S_multispecies_spp71_2 0.0 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Enterobacter.S_multispecies_spp72_2 4.870103364717696 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_multifamily.G_multigenus.S_multispecies_spp76_2 2.776341398811957 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Staphylococcus.S_multispecies_spp82_2 4.328291171814343 - K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Bifidobacteriales.F_Bifidobacteriaceae.G_Bifidobacterium.S_multispecies_spp96_2 5.3143328014222595 WT_Control 5.074585685509224 0.01597069635378018 K_Bacteria.P_Proteobacteria.C_Alphaproteobacteria.O_Hyphomicrobiales.F_Parvibaculaceae.G_Rhodoligotrophos.S_multispecies_sppn5_2_nov_78_502 2.7092122385291297 WT_Control 2.9632960471745107 0.005345676872654241 K_Bacteria 5.999999999999999 - K_Bacteria.P_Firmicutes 5.732791346888163 - K_Bacteria.P_Firmicutes.C_Erysipelotrichia 3.9869250823794955 WT_Control 3.775459760087588 0.009023438818080319 K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales 3.9869250823794955 WT_Control 3.775459760087588 0.009023438818080319 K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Erysipelotrichaceae 3.9748498948324134 WT_Control 3.766280358521363 0.008207736107348857 K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Erysipelotrichaceae.G_Erysipelatoclostridium 0.0 - K_Bacteria.P_Firmicutes.C_Bacilli 5.732382026297763 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales 4.435484180907496 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae 4.435484180907496 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Mammaliicoccus 4.0230207653953824 WT_Control 3.953244534003403 0.005345676872654241 K_Bacteria.P_Actinobacteria 5.567464252001912 WT_Control 5.294321456383127 0.008815858177902031 K_Bacteria.P_Actinobacteria.C_Actinomycetia 5.567464252001912 WT_Control 5.294180345803932 0.008815858177902031 K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Corynebacteriales 5.212590486411491 WT_Control 4.894023885833165 0.018602929901135698 K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Corynebacteriales.F_Corynebacteriaceae 5.212590486411491 WT_Control 4.894024861858725 0.018602929901135698 K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Corynebacteriales.F_Corynebacteriaceae.G_Corynebacterium 5.212590486411491 WT_Control 4.894029062875454 0.018602929901135698 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales 5.714880509679779 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae 5.710491408581364 WT_Tooth+Lig+anti_IL17 5.153777379796717 0.04720176769014229 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus 5.710491408581364 WT_Tooth+Lig+anti_IL17 5.153777379796717 0.04720176769014229 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae 5.313512197678683 WT_Control 4.991756626239611 0.009023438818080319 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Weissella 2.53169303922962 WT_Control 3.267506062663422 0.018602929901135698 K_Bacteria.P_Verrucomicrobia 3.206793207693054 - K_Bacteria.P_Verrucomicrobia.C_Verrucomicrobiae 3.206793207693054 - K_Bacteria.P_Verrucomicrobia.C_Verrucomicrobiae.O_Verrucomicrobiales 3.206793207693054 - K_Bacteria.P_Verrucomicrobia.C_Verrucomicrobiae.O_Verrucomicrobiales.F_Akkermansiaceae 3.206793207693054 - K_Bacteria.P_Verrucomicrobia.C_Verrucomicrobiae.O_Verrucomicrobiales.F_Akkermansiaceae.G_Akkermansia 3.206793207693054 - K_Bacteria.P_Proteobacteria 5.661020451547308 WT_Tooth+Lig+anti_IL17 5.242623483624715 0.04720176769014229 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria 5.661020451547308 WT_Tooth+Lig+anti_IL17 5.243241095228137 0.04720176769014229 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales 5.661020451547308 WT_Tooth+Lig+anti_IL17 5.243241095228137 0.04720176769014229 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Erwiniaceae 4.844783586006577 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Erwiniaceae.G_Pantoea 3.80888710664084 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae 5.485316425193846 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Klebsiella 0.0 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Staphylococcus 4.328952028031106 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Lactobacillus 5.297510576471043 WT_Control 4.975600760487755 0.009023438818080319 K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Erysipelotrichaceae.G_Dubosiella 3.958316082674989 WT_Control 3.770140228962716 0.008207736107348857 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Enterobacter 5.485316425193846 - K_Bacteria.P_Firmicutes.C_Clostridia 3.3575275600194807 - K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales 3.3575275600194807 - K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Peptostreptococcaceae 3.313791049105451 WT_Control 3.211786941874215 0.0070583320485280935 K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Peptostreptococcaceae.G_Romboutsia 3.313791049105451 WT_Control 3.2133033924511927 0.0070583320485280935 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Carnobacteriaceae 3.4485825779174553 WT_Control 3.163742844109431 0.018602929901135698 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Carnobacteriaceae.G_Atopostipes 3.4485825779174553 WT_Control 3.16374373080991 0.018602929901135698 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Erwiniaceae.G_Mixta 4.802837435175647 - K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Erysipelotrichaceae.G_Faecalibaculum 2.5471979034961896 - K_Bacteria.P_Bacteroidetes 4.1867110865278825 WT_Control 3.972636343885508 0.008207736107348857 K_Bacteria.P_Bacteroidetes.C_Bacteroidia 4.1867110865278825 WT_Control 3.9725788445810704 0.008207736107348857 K_Bacteria.P_Bacteroidetes.C_Bacteroidia.O_Bacteroidales 4.1867110865278825 WT_Control 3.972557853347024 0.008207736107348857 K_Bacteria.P_Bacteroidetes.C_Bacteroidia.O_Bacteroidales.F_Muribaculaceae 4.1867110865278825 WT_Control 3.9726038503137926 0.008207736107348857 K_Bacteria.P_Bacteroidetes.C_Bacteroidia.O_Bacteroidales.F_Muribaculaceae.G_Muribaculaceae__G_2_ 4.1867110865278825 WT_Control 3.9726078639733102 0.008207736107348857 K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Planococcaceae 0.0 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Planococcaceae.G_Sporosarcina 0.0 - K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Turicibacteraceae 2.4250110511616256 - K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Turicibacteraceae.G_Turicibacter 2.4250110511616256 - K_Bacteria.P_Cyanobacteria 0.0 - K_Bacteria.P_Cyanobacteria.C_Gloeobacteria 0.0 - K_Bacteria.P_Cyanobacteria.C_Gloeobacteria.O_Gloeobacterales 0.0 - K_Bacteria.P_Cyanobacteria.C_Gloeobacteria.O_Gloeobacterales.F_Gloeobacteraceae 0.0 - K_Bacteria.P_Cyanobacteria.C_Gloeobacteria.O_Gloeobacterales.F_Gloeobacteraceae.G_Gloeobacter 0.0 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_multifamily 4.916450551533582 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_multifamily.G_multigenus 4.916450551533582 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Limosilactobacillus 3.851607195955884 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_multigenus 0.0 - K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Clostridiaceae 2.3389026358734144 - K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Clostridiaceae.G_Clostridium 2.3389026358734144 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Kluyvera 0.0 - K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Lachnospiraceae 2.5199090970627784 - K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Lachnospiraceae.G_Blautia 2.5199090970627784 - K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Bifidobacteriales 5.3143328014222595 WT_Control 5.074603219054384 0.01597069635378018 K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Bifidobacteriales.F_Bifidobacteriaceae 5.3143328014222595 WT_Control 5.074586310327625 0.01597069635378018 K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Bifidobacteriales.F_Bifidobacteriaceae.G_Bifidobacterium 5.3143328014222595 WT_Control 5.074587194104935 0.01597069635378018 K_Bacteria.P_Proteobacteria.C_Alphaproteobacteria 2.7092122385291297 WT_Control 2.968510718286342 0.005345676872654241 K_Bacteria.P_Proteobacteria.C_Alphaproteobacteria.O_Hyphomicrobiales 2.7092122385291297 WT_Control 2.964848463912143 0.005345676872654241 K_Bacteria.P_Proteobacteria.C_Alphaproteobacteria.O_Hyphomicrobiales.F_Parvibaculaceae 2.7092122385291297 WT_Control 2.9620174415700746 0.005345676872654241 K_Bacteria.P_Proteobacteria.C_Alphaproteobacteria.O_Hyphomicrobiales.F_Parvibaculaceae.G_Rhodoligotrophos 2.7092122385291297 WT_Control 2.9689522107451918 0.005345676872654241