K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Erysipelotrichaceae.G_Erysipelatoclostridium.S_ramosum 4.284795551113807 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Mammaliicoccus.S_lentus 4.307703629870244 WT_Imp+Lig+IgG 3.7431772028396897 0.015198983751237766 K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Corynebacteriales.F_Corynebacteriaceae.G_Corynebacterium.S_lowii 5.212193655651761 WT_Control 4.94778209918917 0.024227031852952635 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus.S_faecalis 5.7566809685598015 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Weissella.S_paramesenteroides 5.178476027116726 DB_Control 4.849513959281801 0.00035077561766689506 K_Bacteria.P_Verrucomicrobia.C_Verrucomicrobiae.O_Verrucomicrobiales.F_Akkermansiaceae.G_Akkermansia.S_muciniphila 4.02542549397091 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Erwiniaceae.G_Pantoea.S_conspicua 3.1748642127610007 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Klebsiella.S_variicola 0.0 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Erwiniaceae.G_Pantoea.S_dispersa 0.0 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Staphylococcus.S_ureilyticus 3.5088018503103977 WT_Imp+Lig+IgG 3.1080609446901257 0.0007319594265393062 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Lactobacillus.S_johnsonii 5.271745865843995 DB_Imp+Lig+IgG 4.996177527256062 0.01917460873075946 K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Mammaliicoccus.S_sciuri 4.40304466970195 - K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Corynebacteriales.F_Corynebacteriaceae.G_Corynebacterium.S_tuberculostearicum 2.6584879998526803 WT_Imp+Lig+anti_IL17 2.6846456316270175 0.010640002097527749 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Erwiniaceae.G_Pantoea.S_brenneri 3.2327388937782335 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Staphylococcus.S_capitis 3.638076825938749 - K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Erysipelotrichaceae.G_Dubosiella.S_newyorkensis 3.958316082674989 WT_Control 3.717073085286446 0.011732471055257866 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Enterobacter.S_mori 4.905176478592408 WT_Imp+Lig+anti_IL17 4.631066351535542 0.023654577034758005 K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Peptostreptococcaceae.G_Romboutsia.S_timonensis 3.5800021380461073 DB_Imp+Lig+IgG 3.2967143448762837 5.329543870376476e-05 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Klebsiella.S_pneumoniae 0.0 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Carnobacteriaceae.G_Atopostipes.S_sp__MOT_201 3.4485825779174553 WT_Control 3.1475606624615917 0.00028053701454593984 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Erwiniaceae.G_Mixta.S_calida 4.726642462132888 - K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Erysipelotrichaceae.G_Faecalibaculum.S_rodentium 4.246588270095888 - K_Bacteria.P_Bacteroidetes.C_Bacteroidia.O_Bacteroidales.F_Muribaculaceae.G_Muribaculaceae__G_2_.S_bacterium_MOT_104_nov_90_802 4.332309721323283 DB_Control 4.108576951978362 0.0009087827231564601 K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Planococcaceae.G_Sporosarcina.S_siberiensis_nov_97_892 3.4264553608838098 - K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Turicibacteraceae.G_Turicibacter.S_sanguinis_nov_96_262 4.160326358750153 DB_Control 3.9360671919751398 0.0023254373725873087 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Weissella.S_paramesenteroides_nov_94_614 4.091584404985806 DB_Control 3.8098254201306476 8.01457645640942e-05 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus.S_faecalis_nov_94_614 4.00948302304259 DB_Control 3.706773262481257 0.00015240680676341148 K_Bacteria.P_Bacteroidetes.C_Bacteroidia.O_Bacteroidales.F_Muribaculaceae.G_Muribaculaceae__G_2_.S_bacterium_MOT_104_nov_89_810 3.2495144341485465 DB_Control 3.054683912434358 0.0097097779989367 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus.S_faecalis_nov_97_424 2.5838537295890376 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus.S_faecalis_nov_94_626 4.290544154429747 DB_Control 3.9709406009221864 0.0027255649000004017 K_Bacteria.P_Cyanobacteria.C_Gloeobacteria.O_Gloeobacterales.F_Gloeobacteraceae.G_Gloeobacter.S_kilaueensis_nov_81_638 2.0190578093944787 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Lactobacillus.S_johnsonii_nov_94_626 4.230081400487001 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus.S_multispecies_spp12_2 5.6875140864720635 WT_Imp+Lig+IgG 5.391208652377557 0.002689290326773392 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_multifamily.G_multigenus.S_multispecies_spp143_4 5.337841466245032 DB_Imp+Lig+anti_IL17 4.935735003591452 0.02071162308212062 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Limosilactobacillus.S_multispecies_spp16_2 3.851607195955884 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_multigenus.S_multispecies_spp21_6 0.0 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Enterobacter.S_multispecies_spp22_4 4.781841977899934 - K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Clostridiaceae.G_Clostridium.S_multispecies_spp28_2 3.1015936928526457 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus.S_multispecies_spp29_5 2.4230218925469122 DB_Control 2.7926424392765608 0.0021229258772509254 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Kluyvera.S_multispecies_spp39_2 0.0 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_multigenus.S_multispecies_spp41_2 0.0 - K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Lachnospiraceae.G_Blautia.S_multispecies_spp48_3 2.5081596855635926 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus.S_multispecies_spp57_3 4.010788337287144 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Staphylococcus.S_multispecies_spp59_3 4.40153524297447 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Klebsiella.S_multispecies_spp71_2 0.0 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Enterobacter.S_multispecies_spp72_2 5.106459503288375 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_multifamily.G_multigenus.S_multispecies_spp76_2 3.3876671240911973 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Staphylococcus.S_multispecies_spp82_2 4.1841481645851095 WT_Control 3.886067895628997 0.02125209671562888 K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Bifidobacteriales.F_Bifidobacteriaceae.G_Bifidobacterium.S_multispecies_spp96_2 5.3143328014222595 - K_Bacteria.P_Proteobacteria.C_Alphaproteobacteria.O_Hyphomicrobiales.F_Parvibaculaceae.G_Rhodoligotrophos.S_multispecies_sppn5_2_nov_78_502 2.7092122385291297 WT_Control 2.5903675283159595 2.5506021991425736e-05 K_Bacteria 5.999999999999999 - K_Bacteria.P_Firmicutes 5.9382799870183565 - K_Bacteria.P_Firmicutes.C_Erysipelotrichia 4.304085853416705 DB_Imp+Lig+IgG 4.1436951674973415 0.01648637601919136 K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales 4.304085853416705 DB_Imp+Lig+IgG 4.140595152655004 0.01648637601919136 K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Erysipelotrichaceae 4.286125680329569 - K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Erysipelotrichaceae.G_Erysipelatoclostridium 4.284795551113807 - K_Bacteria.P_Firmicutes.C_Bacilli 5.930598814042088 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales 4.783617593387572 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae 4.783617593387572 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Mammaliicoccus 4.40304466970195 - K_Bacteria.P_Actinobacteria 5.567464252001912 WT_Control 5.287176024774718 0.007521755262188104 K_Bacteria.P_Actinobacteria.C_Actinomycetia 5.567464252001912 WT_Control 5.287175963193106 0.007521755262188104 K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Corynebacteriales 5.212590486411491 WT_Control 4.922131340312568 0.027593590931580647 K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Corynebacteriales.F_Corynebacteriaceae 5.212590486411491 WT_Control 4.922356299955302 0.027593590931580647 K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Corynebacteriales.F_Corynebacteriaceae.G_Corynebacterium 5.212590486411491 WT_Control 4.922216558470693 0.027593590931580647 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales 5.929508069100666 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae 5.818907271251665 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus 5.818907271251665 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae 5.499612021216544 DB_Control 5.188294871549444 0.01462011981582802 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Weissella 5.212649863205546 DB_Control 4.886406674925323 0.0003068191614465305 K_Bacteria.P_Verrucomicrobia 4.02542549397091 - K_Bacteria.P_Verrucomicrobia.C_Verrucomicrobiae 4.02542549397091 - K_Bacteria.P_Verrucomicrobia.C_Verrucomicrobiae.O_Verrucomicrobiales 4.02542549397091 - K_Bacteria.P_Verrucomicrobia.C_Verrucomicrobiae.O_Verrucomicrobiales.F_Akkermansiaceae 4.02542549397091 - K_Bacteria.P_Verrucomicrobia.C_Verrucomicrobiae.O_Verrucomicrobiales.F_Akkermansiaceae.G_Akkermansia 4.02542549397091 - K_Bacteria.P_Proteobacteria 5.58388997325017 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria 5.583737320951368 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales 5.583737320951368 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Erwiniaceae 4.752005059707982 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Erwiniaceae.G_Pantoea 3.5057948938972263 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae 5.340511065334383 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Klebsiella 0.0 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Staphylococcus 4.6066405486907875 WT_Imp+Lig+IgG 4.379797199917542 0.014982139643934569 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Lactobacillus 5.297510576471043 WT_Control 5.0179582467239765 0.023625052669938328 K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Erysipelotrichaceae.G_Dubosiella 3.958316082674989 WT_Control 3.7175759776083432 0.011732471055257866 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Enterobacter 5.340511065334383 - K_Bacteria.P_Firmicutes.C_Clostridia 3.704619434521082 DB_Imp+Lig+IgG 3.4544385536580906 0.017343360924647805 K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales 3.704619434521082 DB_Imp+Lig+IgG 3.460690610296795 0.017343360924647805 K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Peptostreptococcaceae 3.5800021380461073 DB_Imp+Lig+IgG 3.3264826299603145 5.329543870376476e-05 K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Peptostreptococcaceae.G_Romboutsia 3.5800021380461073 DB_Imp+Lig+IgG 3.349095864112893 5.329543870376476e-05 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Carnobacteriaceae 3.4485825779174553 WT_Control 3.1475748076763312 0.00028053701454593984 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Carnobacteriaceae.G_Atopostipes 3.4485825779174553 WT_Control 3.1476394382032282 0.00028053701454593984 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Erwiniaceae.G_Mixta 4.726642462132888 - K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Erysipelotrichaceae.G_Faecalibaculum 4.246588270095888 - K_Bacteria.P_Bacteroidetes 4.366794889658498 DB_Control 4.1433748681033284 0.0008828942956402728 K_Bacteria.P_Bacteroidetes.C_Bacteroidia 4.366794889658498 DB_Control 4.1433961563959585 0.0008828942956402728 K_Bacteria.P_Bacteroidetes.C_Bacteroidia.O_Bacteroidales 4.366794889658498 DB_Control 4.143367876931793 0.0008828942956402728 K_Bacteria.P_Bacteroidetes.C_Bacteroidia.O_Bacteroidales.F_Muribaculaceae 4.366794889658498 DB_Control 4.143392474283072 0.0008828942956402728 K_Bacteria.P_Bacteroidetes.C_Bacteroidia.O_Bacteroidales.F_Muribaculaceae.G_Muribaculaceae__G_2_ 4.366794889658498 DB_Control 4.1433687082511055 0.0008828942956402728 K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Planococcaceae 3.4264553608838098 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Planococcaceae.G_Sporosarcina 3.4264553608838098 - K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Turicibacteraceae 4.160326358750153 DB_Control 3.9360650512835837 0.0023254373725873087 K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Turicibacteraceae.G_Turicibacter 4.160326358750153 DB_Control 3.9360796116019388 0.0023254373725873087 K_Bacteria.P_Cyanobacteria 2.0190578093944787 - K_Bacteria.P_Cyanobacteria.C_Gloeobacteria 2.0190578093944787 - K_Bacteria.P_Cyanobacteria.C_Gloeobacteria.O_Gloeobacterales 2.0190578093944787 - K_Bacteria.P_Cyanobacteria.C_Gloeobacteria.O_Gloeobacterales.F_Gloeobacteraceae 2.0190578093944787 - K_Bacteria.P_Cyanobacteria.C_Gloeobacteria.O_Gloeobacterales.F_Gloeobacteraceae.G_Gloeobacter 2.0190578093944787 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_multifamily 5.338581076131282 DB_Imp+Lig+anti_IL17 4.902058142697846 0.034684040379089696 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_multifamily.G_multigenus 5.338581076131282 DB_Imp+Lig+anti_IL17 4.932115284824388 0.034684040379089696 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Limosilactobacillus 3.851607195955884 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_multigenus 0.0 - K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Clostridiaceae 3.1015936928526457 - K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Clostridiaceae.G_Clostridium 3.1015936928526457 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Kluyvera 0.0 - K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Lachnospiraceae 2.5081596855635926 - K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Lachnospiraceae.G_Blautia 2.5081596855635926 - K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Bifidobacteriales 5.3143328014222595 - K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Bifidobacteriales.F_Bifidobacteriaceae 5.3143328014222595 - K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Bifidobacteriales.F_Bifidobacteriaceae.G_Bifidobacterium 5.3143328014222595 - K_Bacteria.P_Proteobacteria.C_Alphaproteobacteria 2.7092122385291297 WT_Control 2.59006882537774 2.5506021991425736e-05 K_Bacteria.P_Proteobacteria.C_Alphaproteobacteria.O_Hyphomicrobiales 2.7092122385291297 WT_Control 2.5885065786212476 2.5506021991425736e-05 K_Bacteria.P_Proteobacteria.C_Alphaproteobacteria.O_Hyphomicrobiales.F_Parvibaculaceae 2.7092122385291297 WT_Control 2.587828225175423 2.5506021991425736e-05 K_Bacteria.P_Proteobacteria.C_Alphaproteobacteria.O_Hyphomicrobiales.F_Parvibaculaceae.G_Rhodoligotrophos 2.7092122385291297 WT_Control 2.5858333284276744 2.5506021991425736e-05