K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Erysipelotrichaceae.G_Erysipelatoclostridium.S_ramosum 4.278733327724799 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Mammaliicoccus.S_lentus 4.772094529586975 WT_Tooth+Lig+IgG 4.485603339291413 0.007616533148713935 K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Corynebacteriales.F_Corynebacteriaceae.G_Corynebacterium.S_lowii 5.212193655651761 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus.S_faecalis 5.702598843325122 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Weissella.S_paramesenteroides 5.178476027116726 DB_Control 4.862276297620306 5.871826896391104e-05 K_Bacteria.P_Verrucomicrobia.C_Verrucomicrobiae.O_Verrucomicrobiales.F_Akkermansiaceae.G_Akkermansia.S_muciniphila 3.206793207693054 WT_Control 2.8929445801540643 0.038327278922072515 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Erwiniaceae.G_Pantoea.S_conspicua 3.6544795354419675 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Klebsiella.S_variicola 4.802638425156734 DB_Tooth+Lig+anti_IL17 4.452788270149256 0.0459332278691278 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Erwiniaceae.G_Pantoea.S_dispersa 0.0 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Staphylococcus.S_ureilyticus 3.155985009382931 WT_Control 2.9715220171745385 0.0007942445996529516 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Lactobacillus.S_johnsonii 5.374731423384561 DB_Tooth+Lig+IgG 5.134126591714829 0.002285229295202718 K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Mammaliicoccus.S_sciuri 3.9987756407768873 - K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Corynebacteriales.F_Corynebacteriaceae.G_Corynebacterium.S_tuberculostearicum 2.173213103298496 WT_Control 2.497385731359453 0.005863543984964819 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Erwiniaceae.G_Pantoea.S_brenneri 3.28485259414625 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Staphylococcus.S_capitis 3.924547854018689 - K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Erysipelotrichaceae.G_Dubosiella.S_newyorkensis 3.958316082674989 WT_Control 3.6410431965632757 0.0001665142798518962 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Enterobacter.S_mori 5.1177651593741045 WT_Tooth+Lig+anti_IL17 4.772614263026356 0.010141203402847757 K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Peptostreptococcaceae.G_Romboutsia.S_timonensis 3.313791049105451 WT_Control 3.049504520716393 6.569801868036882e-05 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Klebsiella.S_pneumoniae 3.9424401117380157 DB_Tooth+Lig+anti_IL17 3.6050524438959224 0.0459332278691278 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Carnobacteriaceae.G_Atopostipes.S_sp__MOT_201 3.4485825779174553 WT_Control 3.178536214624862 0.00015378921174533146 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Erwiniaceae.G_Mixta.S_calida 4.802837435175647 - K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Erysipelotrichaceae.G_Faecalibaculum.S_rodentium 2.5471979034961896 WT_Control 2.5020923844248464 0.013013636393374297 K_Bacteria.P_Bacteroidetes.C_Bacteroidia.O_Bacteroidales.F_Muribaculaceae.G_Muribaculaceae__G_2_.S_bacterium_MOT_104_nov_90_802 4.332309721323283 DB_Control 4.1045245833043555 2.1344209542980517e-06 K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Planococcaceae.G_Sporosarcina.S_siberiensis_nov_97_892 0.0 - K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Turicibacteraceae.G_Turicibacter.S_sanguinis_nov_96_262 4.160326358750153 DB_Control 3.9468134538853286 0.0010905569275601427 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Weissella.S_paramesenteroides_nov_94_614 4.091584404985806 DB_Control 3.794153631846438 8.904922888601998e-05 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus.S_faecalis_nov_94_614 4.00948302304259 DB_Control 3.704189371371534 0.00015685197850775847 K_Bacteria.P_Bacteroidetes.C_Bacteroidia.O_Bacteroidales.F_Muribaculaceae.G_Muribaculaceae__G_2_.S_bacterium_MOT_104_nov_89_810 3.2495144341485465 DB_Control 3.0469289620509485 0.0003182426416283257 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus.S_faecalis_nov_97_424 1.6318073072164665 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus.S_faecalis_nov_94_626 4.290544154429747 DB_Control 4.002345067314821 0.0020811363752172986 K_Bacteria.P_Cyanobacteria.C_Gloeobacteria.O_Gloeobacterales.F_Gloeobacteraceae.G_Gloeobacter.S_kilaueensis_nov_81_638 0.0 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Lactobacillus.S_johnsonii_nov_94_626 4.230081400487001 DB_Control 3.9191498886261105 0.013002750368710339 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus.S_multispecies_spp12_2 5.651102325277935 WT_Tooth+Lig+IgG 5.342475987123862 0.0018765616009083815 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_multifamily.G_multigenus.S_multispecies_spp143_4 5.399846503139603 DB_Tooth+Lig+anti_IL17 5.090543566046498 0.006173344274481641 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Limosilactobacillus.S_multispecies_spp16_2 3.851607195955884 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_multigenus.S_multispecies_spp21_6 0.0 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Enterobacter.S_multispecies_spp22_4 5.0018074576996865 WT_Tooth+Lig+anti_IL17 4.656758762101227 0.040947729034806674 K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Clostridiaceae.G_Clostridium.S_multispecies_spp28_2 2.5328607217768107 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus.S_multispecies_spp29_5 2.4230218925469122 DB_Control 2.6107895731285273 0.001388453059225473 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Kluyvera.S_multispecies_spp39_2 0.0 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_multigenus.S_multispecies_spp41_2 0.0 - K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Lachnospiraceae.G_Blautia.S_multispecies_spp48_3 2.529009350658499 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus.S_multispecies_spp57_3 4.277920943148596 DB_Tooth+Lig+anti_IL17 4.007648298923978 0.006594212052061 K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Staphylococcus.S_multispecies_spp59_3 4.711447555724744 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Klebsiella.S_multispecies_spp71_2 3.981316665990998 DB_Tooth+Lig+anti_IL17 3.6520228061228788 0.0459332278691278 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Enterobacter.S_multispecies_spp72_2 5.16578770340354 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_multifamily.G_multigenus.S_multispecies_spp76_2 2.776341398811957 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Staphylococcus.S_multispecies_spp82_2 4.328291171814343 WT_Tooth+Lig+anti_IL17 3.9490804243821316 0.001484487101422312 K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Bifidobacteriales.F_Bifidobacteriaceae.G_Bifidobacterium.S_multispecies_spp96_2 5.3143328014222595 WT_Control 5.001289842635207 0.007339513381871844 K_Bacteria.P_Proteobacteria.C_Alphaproteobacteria.O_Hyphomicrobiales.F_Parvibaculaceae.G_Rhodoligotrophos.S_multispecies_sppn5_2_nov_78_502 2.7092122385291297 WT_Control 2.5602423691753287 4.192583817452245e-07 K_Bacteria 5.999999999999999 - K_Bacteria.P_Firmicutes 5.9382799870183565 - K_Bacteria.P_Firmicutes.C_Erysipelotrichia 4.309319049651034 WT_Tooth+Lig+IgG 4.07087663373282 0.0015643632014573521 K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales 4.309319049651034 WT_Tooth+Lig+IgG 4.0708070192439845 0.0015643632014573521 K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Erysipelotrichaceae 4.27879978868852 WT_Tooth+Lig+IgG 4.024731503928498 0.013827822594868592 K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Erysipelotrichaceae.G_Erysipelatoclostridium 4.278733327724799 - K_Bacteria.P_Firmicutes.C_Bacilli 5.930598814042088 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales 5.084006971489725 WT_Tooth+Lig+IgG 4.78370490538692 0.016226665806884547 K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae 5.084006971489725 WT_Tooth+Lig+IgG 4.783707471385685 0.016226665806884547 K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Mammaliicoccus 4.772094529586975 WT_Tooth+Lig+IgG 4.4990617244148385 0.011282035284419642 K_Bacteria.P_Actinobacteria 5.567464252001912 WT_Control 5.241123789879025 0.04048796814115598 K_Bacteria.P_Actinobacteria.C_Actinomycetia 5.567464252001912 WT_Control 5.240992575063061 0.04048796814115598 K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Corynebacteriales 5.212590486411491 WT_Control 4.8721972094078785 0.04411275420453701 K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Corynebacteriales.F_Corynebacteriaceae 5.212590486411491 WT_Control 4.872197222277789 0.04411275420453701 K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Corynebacteriales.F_Corynebacteriaceae.G_Corynebacterium 5.212590486411491 WT_Control 4.872197213319546 0.04411275420453701 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales 5.929508069100666 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae 5.789243062789053 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Enterococcaceae.G_Enterococcus 5.789243062789053 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae 5.499612021216544 DB_Control 5.208756565856216 0.0019987962293303795 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Weissella 5.212649863205546 DB_Control 4.897791796420336 5.636958637055519e-05 K_Bacteria.P_Verrucomicrobia 3.206793207693054 WT_Control 2.8947490619265888 0.038327278922072515 K_Bacteria.P_Verrucomicrobia.C_Verrucomicrobiae 3.206793207693054 WT_Control 2.892384766437435 0.038327278922072515 K_Bacteria.P_Verrucomicrobia.C_Verrucomicrobiae.O_Verrucomicrobiales 3.206793207693054 WT_Control 2.8949130719467373 0.038327278922072515 K_Bacteria.P_Verrucomicrobia.C_Verrucomicrobiae.O_Verrucomicrobiales.F_Akkermansiaceae 3.206793207693054 WT_Control 2.8913414469204004 0.038327278922072515 K_Bacteria.P_Verrucomicrobia.C_Verrucomicrobiae.O_Verrucomicrobiales.F_Akkermansiaceae.G_Akkermansia 3.206793207693054 WT_Control 2.894259384029764 0.038327278922072515 K_Bacteria.P_Proteobacteria 5.712479567716114 DB_Tooth+Lig+anti_IL17 5.306292956144895 0.011919030656704929 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria 5.712479567716114 DB_Tooth+Lig+anti_IL17 5.306292955852085 0.011919030656704929 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales 5.712479567716114 DB_Tooth+Lig+anti_IL17 5.306292955852085 0.011919030656704929 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Erwiniaceae 4.844783586006577 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Erwiniaceae.G_Pantoea 3.80888710664084 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae 5.485316425193846 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Klebsiella 4.9128480747297125 DB_Tooth+Lig+anti_IL17 4.571723606290534 0.0459332278691278 K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Staphylococcaceae.G_Staphylococcus 4.79359338506631 WT_Tooth+Lig+IgG 4.497399726166517 0.008237206955949938 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Lactobacillus 5.390605182734909 DB_Tooth+Lig+IgG 5.1489427185239585 0.0025300868977004677 K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Erysipelotrichaceae.G_Dubosiella 3.958316082674989 WT_Control 3.6410211565935287 0.0001665142798518962 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Enterobacter 5.485316425193846 - K_Bacteria.P_Firmicutes.C_Clostridia 3.3575275600194807 WT_Control 3.082948840307909 0.022086649693398745 K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales 3.3575275600194807 WT_Control 3.08282635658979 0.022086649693398745 K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Peptostreptococcaceae 3.313791049105451 WT_Control 3.0500717747079187 6.569801868036882e-05 K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Peptostreptococcaceae.G_Romboutsia 3.313791049105451 WT_Control 3.047209141339683 6.569801868036882e-05 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Carnobacteriaceae 3.4485825779174553 WT_Control 3.178536974443605 0.00015378921174533146 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Carnobacteriaceae.G_Atopostipes 3.4485825779174553 WT_Control 3.1785409838984346 0.00015378921174533146 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Erwiniaceae.G_Mixta 4.802837435175647 - K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Erysipelotrichaceae.G_Faecalibaculum 2.5471979034961896 WT_Control 2.5028038210733246 0.013013636393374297 K_Bacteria.P_Bacteroidetes 4.366794889658498 DB_Control 4.139564080051889 4.248522466788226e-06 K_Bacteria.P_Bacteroidetes.C_Bacteroidia 4.366794889658498 DB_Control 4.139564009077923 4.248522466788226e-06 K_Bacteria.P_Bacteroidetes.C_Bacteroidia.O_Bacteroidales 4.366794889658498 DB_Control 4.139563991673402 4.248522466788226e-06 K_Bacteria.P_Bacteroidetes.C_Bacteroidia.O_Bacteroidales.F_Muribaculaceae 4.366794889658498 DB_Control 4.1395640336818555 4.248522466788226e-06 K_Bacteria.P_Bacteroidetes.C_Bacteroidia.O_Bacteroidales.F_Muribaculaceae.G_Muribaculaceae__G_2_ 4.366794889658498 DB_Control 4.139564029445558 4.248522466788226e-06 K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Planococcaceae 0.0 - K_Bacteria.P_Firmicutes.C_Bacilli.O_Bacillales.F_Planococcaceae.G_Sporosarcina 0.0 - K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Turicibacteraceae 4.160326358750153 DB_Control 3.9468103049637433 0.0010905569275601427 K_Bacteria.P_Firmicutes.C_Erysipelotrichia.O_Erysipelotrichales.F_Turicibacteraceae.G_Turicibacter 4.160326358750153 DB_Control 3.946820650011119 0.0010905569275601427 K_Bacteria.P_Cyanobacteria 0.0 - K_Bacteria.P_Cyanobacteria.C_Gloeobacteria 0.0 - K_Bacteria.P_Cyanobacteria.C_Gloeobacteria.O_Gloeobacterales 0.0 - K_Bacteria.P_Cyanobacteria.C_Gloeobacteria.O_Gloeobacterales.F_Gloeobacteraceae 0.0 - K_Bacteria.P_Cyanobacteria.C_Gloeobacteria.O_Gloeobacterales.F_Gloeobacteraceae.G_Gloeobacter 0.0 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_multifamily 5.399846503139603 DB_Tooth+Lig+anti_IL17 5.091583628730744 0.006321306732438579 K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_multifamily.G_multigenus 5.399846503139603 DB_Tooth+Lig+anti_IL17 5.091533068727602 0.006321306732438579 K_Bacteria.P_Firmicutes.C_Bacilli.O_Lactobacillales.F_Lactobacillaceae.G_Limosilactobacillus 3.851607195955884 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_multigenus 0.0 - K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Clostridiaceae 2.5328607217768107 - K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Clostridiaceae.G_Clostridium 2.5328607217768107 - K_Bacteria.P_Proteobacteria.C_Gammaproteobacteria.O_Enterobacterales.F_Enterobacteriaceae.G_Kluyvera 0.0 - K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Lachnospiraceae 2.529009350658499 - K_Bacteria.P_Firmicutes.C_Clostridia.O_Eubacteriales.F_Lachnospiraceae.G_Blautia 2.529009350658499 - K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Bifidobacteriales 5.3143328014222595 WT_Control 5.001305004738768 0.007339513381871844 K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Bifidobacteriales.F_Bifidobacteriaceae 5.3143328014222595 WT_Control 5.001324992704396 0.007339513381871844 K_Bacteria.P_Actinobacteria.C_Actinomycetia.O_Bifidobacteriales.F_Bifidobacteriaceae.G_Bifidobacterium 5.3143328014222595 WT_Control 5.00122373704035 0.007339513381871844 K_Bacteria.P_Proteobacteria.C_Alphaproteobacteria 2.7092122385291297 WT_Control 2.5618653063548975 4.192583817452245e-07 K_Bacteria.P_Proteobacteria.C_Alphaproteobacteria.O_Hyphomicrobiales 2.7092122385291297 WT_Control 2.5611872772531177 4.192583817452245e-07 K_Bacteria.P_Proteobacteria.C_Alphaproteobacteria.O_Hyphomicrobiales.F_Parvibaculaceae 2.7092122385291297 WT_Control 2.5614458395397603 4.192583817452245e-07 K_Bacteria.P_Proteobacteria.C_Alphaproteobacteria.O_Hyphomicrobiales.F_Parvibaculaceae.G_Rhodoligotrophos 2.7092122385291297 WT_Control 2.5607553509046954 4.192583817452245e-07