Percentile	0.0	25.0	50.0	75.0	100.0	0.0	25.0	50.0	75.0	100.0
Group	Male Brain Genotype- SPM+ Treated	Male Brain Genotype- SPM+ Treated	Male Brain Genotype- SPM+ Treated	Male Brain Genotype- SPM+ Treated	Male Brain Genotype- SPM+ Treated	Male Ligature Genotype- SPM+ Treated	Male Ligature Genotype- SPM+ Treated	Male Ligature Genotype- SPM+ Treated	Male Ligature Genotype- SPM+ Treated	Male Ligature Genotype- SPM+ Treated
Porphyromonas gingivalis (SP1)	1.0	4387.5	8774.0	9986.0	11198.0	1.0	1.0	1.0	2.5	4.0
Enterococcus gallinarum (SP100)	1.0	1.0	1.0	786.0	1571.0	1.0	4.5	8.0	1034.5	2061.0
Fusobacterium nucleatum_subsp._vincentii (SP102)	1.0	1.0	1.0	1383.0	2765.0	1.0	1.0	1.0	3.5	6.0
Enterobacter cancerogenus (SP103)	1.0	32.0	63.0	273.0	483.0	1.0	1.0	1.0	1.0	1.0
Bacillus licheniformis (SP116)	1.0	1.0	1.0	1548.5	3096.0	1.0	1.0	1.0	1.0	1.0
Peptostreptococcus stomatis (SP117)	1.0	1.0	1.0	352.0	703.0	1.0	1.0	1.0	1.0	1.0
Fusobacterium nucleatum (SP13)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	4.5	8.0
Phocaeicola sartorii (SP132)	1.0	1.0	1.0	1.0	1.0	473.0	927.0	1381.0	2753.5	4126.0
Corynebacterium pilbarense (SP133)	1.0	1.0	1.0	1743.5	3486.0	1.0	1.0	1.0	1.0	1.0
Sphingomonas echinoides (SP134)	1.0	1.0	1.0	783.0	1565.0	1.0	1.0	1.0	1.0	1.0
Citrobacter koseri (SP142)	1.0	1.0	1.0	1917.0	3833.0	1.0	1.0	1.0	1.0	1.0
Chryseobacterium gambrini (SP143)	1.0	1.0	1.0	401.0	801.0	1.0	1.0	1.0	1.0	1.0
Enterobacter hormaechei (SP15)	1.0	2135.5	4270.0	5939.5	7609.0	1.0	1.0	1.0	1.0	1.0
Treponema sp. HMT257 (SP150)	1.0	1.0	1.0	1458.5	2916.0	1.0	1.0	1.0	1.0	1.0
Pseudomonas putida (SP151)	1.0	1.0	1.0	254.0	507.0	1.0	1.0	1.0	1.0	1.0
Veillonella atypica (SP155)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.5	4.0
Adlercreutzia mucosicola (SP16)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	4.0	7.0
Granulicatella adiacens (SP169)	1.0	1.0	1.0	431.5	862.0	1.0	1.0	1.0	1.0	1.0
Klebsiella pneumoniae (SP17)	1429.0	1604.5	1780.0	1856.5	1933.0	132834.0	151409.0	169984.0	178541.0	187098.0
Actinomyces sp. HMT170 (SP177)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	4.5	8.0
Ligilactobacillus murinus (SP18)	1.0	1.0	1.0	1.0	1.0	619.0	3407.5	6196.0	20580.0	34964.0
Streptococcus thermophilus (SP182)	1.0	1.0	1.0	550.5	1100.0	1.0	1.0	1.0	1.0	1.0
Adlercreutzia caecimuris (SP184)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	6.0	11.0
Bacteroides caccae (SP195)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	58.0	115.0
Kosakonia sacchari (SP20)	653.0	1325.0	1997.0	2871.5	3746.0	1.0	1.0	1.0	1.0	1.0
Micrococcus aloeverae (SP200)	1.0	1.0	1.0	2796.5	5592.0	1.0	1.0	1.0	1.0	1.0
Selenomonas sputigena (SP206)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.0	3.0
Streptococcus sanguinis (SP207)	1.0	1.0	1.0	715.5	1430.0	1.0	1.0	1.0	1.0	1.0
Lachnospiraceae_[G-8] bacterium HMT500 (SP210)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.5	4.0
Corynebacterium xerosis (SP211)	1.0	1.0	1.0	1708.5	3416.0	1.0	1.0	1.0	1.0	1.0
Corynebacterium mucifaciens (SP225)	1.0	1.0	1.0	5178.5	10356.0	1.0	1.0	1.0	1.0	1.0
Saccharibacteria_(TM7)_[G-1] bacterium HMT348 (SP232)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	4.5	8.0
Corynebacterium amycolatum (SP26)	1.0	1.0	1.0	7037.0	14073.0	1.0	1.0	1.0	1.0	1.0
Enterobacter cloacae (SP28)	1.0	9.5	18.0	432.5	847.0	1.0	6.0	11.0	246.5	482.0
Veillonella parvula (SP33)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.0	3.0
Enterococcus faecalis (SP37)	1.0	1.0	1.0	1.0	1.0	10196.0	31603.5	53011.0	68322.0	83633.0
Faecalibaculum rodentium (SP39)	1.0	1.0	1.0	1.0	1.0	1.0	103.0	205.0	5353.5	10502.0
Cutibacterium acnes (SP41)	1.0	4671.0	9341.0	12454.0	15567.0	10.0	274.0	538.0	591.0	644.0
Acinetobacter johnsonii (SP42)	1.0	1.0	1.0	4606.5	9212.0	1.0	1.0	1.0	1.0	1.0
Acinetobacter tjernbergiae (SP46)	1.0	1.0	1.0	1058.5	2116.0	1.0	1.0	1.0	1.0	1.0
Lawsonella clevelandensis (SP47)	1.0	1.0	1.0	472.0	943.0	1.0	1.0	1.0	1.0	1.0
Prevotella sp. HMT304 (SP50)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	3.0	5.0
Corynebacterium stationis (SP58)	1.0	1.0	1.0	528.5	1056.0	1.0	1.0	1.0	1.0	1.0
Limosilactobacillus reuteri (SP65)	1.0	1.0	1.0	1.0	1.0	1.0	3.5	6.0	6.5	7.0
Treponema sp. HMT237 (SP66)	1.0	1.0	1.0	432.0	863.0	1.0	1.0	1.0	3.0	5.0
Corynebacterium mastitidis (SP67)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	393.0	785.0
Mammaliicoccus lentus (SP68)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	8.5	16.0
Neisseriaceae_[G-1] bacterium_MOT-031 (SP69)	1.0	1.0	1.0	1.0	1.0	32.0	96.5	161.0	542.0	923.0
Streptococcus thoraltensis (SP70)	1.0	16487.0	32973.0	56515.5	80058.0	778.0	9258.0	17738.0	25773.0	33808.0
Streptococcus danieliae (SP73)	1.0	1.0	1.0	1.0	1.0	66.0	230.5	395.0	1974.0	3553.0
Streptococcus oralis_subsp._tigurinus_clade_070 (SP79)	1.0	1.0	1.0	635.5	1270.0	1.0	1.0	1.0	1.0	1.0
Proteus mirabilis (SP8)	1.0	1.0	1.0	467.5	934.0	1.0	1.0	1.0	248.5	496.0
Aggregatibacter sp. HMT512 (SP80)	1.0	1.0	1.0	45.5	90.0	1.0	1.0	1.0	1.0	1.0
Mammaliicoccus sciuri (SP85)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	147.5	294.0
Atopobium vaginae (SP86)	1.0	1.0	1.0	1726.5	3452.0	1.0	1.0	1.0	1.0	1.0
Peptoniphilus indolicus (SP87)	1.0	1.0	1.0	4010.5	8020.0	1.0	1.0	1.0	1.0	1.0
Faecalibaculum rodentium_nov_96.715% (SPN108)	1.0	1.0	1.0	1.0	1.0	1.0	67.0	133.0	569.0	1005.0
Muribaculaceae_[G-1] bacterium_MOT-129_nov_89.452% (SPN110)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.0	3.0
Lachnospiraceae_[G-3] bacterium_MOT-168_nov_93.319% (SPN114)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	6.5	12.0
Slackia piriformis_nov_88.985% (SPN116)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.0	3.0
Muribaculaceae_[G-2] bacterium_MOT-104_nov_90.600% (SPN117)	1.0	1.0	1.0	1.0	1.0	1.0	2.5	4.0	8.5	13.0
Prevotella shahii_nov_87.602% (SPN118)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.5	4.0
Duncaniella freteri_nov_89.113% (SPN120)	1.0	1.0	1.0	464.5	928.0	1.0	1.0	1.0	4.5	8.0
Duncaniella freteri_nov_89.718% (SPN127)	1.0	1.0	1.0	625.0	1249.0	1.0	1.0	1.0	6.5	12.0
Muribaculaceae_[G-1] bacterium_MOT-129_nov_85.887% (SPN131)	1.0	1.0	1.0	1.0	1.0	1.0	3.0	5.0	11.5	18.0
Duncaniella freteri_nov_90.612% (SPN132)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	7.0	13.0
Alloprevotella sp. HMT473 nov_89.366% (SPN134)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	16.0	31.0
Mageeibacillus indolicus_nov_87.730% (SPN135)	1.0	1.0	1.0	361.0	721.0	1.0	1.0	1.0	1.0	1.0
Peptoniphilus indolicus_nov_97.699% (SPN14)	1.0	1.0	1.0	1005.0	2009.0	1.0	1.0	1.0	1.0	1.0
Saccharibacteria_(TM7)_[G-3] bacterium HMT351 nov_95.400% (SPN17)	1.0	1.0	1.0	1.0	1.0	1.0	4.0	7.0	9.0	11.0
Parasutterella excrementihominis_nov_94.578% (SPN24)	1.0	1.0	1.0	1.0	1.0	1.0	47.5	94.0	98.0	102.0
Nocardioides salsibiostraticola_nov_84.805% (SPN27)	1.0	1.0	1.0	9.5	18.0	1.0	1.0	1.0	1.0	1.0
Duncaniella freteri_nov_93.293% (SPN35)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	3.5	6.0
Duncaniella freteri_nov_91.853% (SPN37)	1.0	1.0	1.0	483.5	966.0	1.0	1.0	1.0	1.0	1.0
Corynebacterium matruchotii_nov_88.330% (SPN39)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	8.0	15.0
Lachnospiraceae_[G-3] bacterium_MOT-168_nov_94.792% (SPN41)	1.0	1.0	1.0	428.5	856.0	1.0	1.0	1.0	1.0	1.0
Paludibaculum fermentans_nov_91.051% (SPN46)	1.0	1.0	1.0	339.0	677.0	1.0	1.0	1.0	1.0	1.0
Streptococcus thoraltensis_nov_91.881% (SPN47)	1.0	1.0	1.0	6.0	11.0	1.0	1.0	1.0	1.0	1.0
Muribaculaceae_[G-1] bacterium_MOT-129_nov_83.636% (SPN5)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	13.0	25.0
Streptococcus azizii_nov_95.171% (SPN52)	1.0	1.0	1.0	1.0	1.0	15.0	18.5	22.0	36.5	51.0
Acinetobacter johnsonii_nov_97.531% (SPN6)	1.0	1.0	1.0	1718.0	3435.0	1.0	1.0	1.0	1.0	1.0
Pseudoflavonifractor capillosus_nov_90.103% (SPN65)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	4.5	8.0
Piscirickettsia salmonis_nov_78.585% (SPN66)	1.0	1.0	1.0	4.5	8.0	1.0	1.0	1.0	1.0	1.0
Lachnospiraceae_[G-14] bacterium_MOT-185_nov_96.781% (SPN67)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	4.5	8.0
Gynuella sunshinyii_nov_78.384% (SPN69)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	4.5	8.0
Muribaculaceae_[G-2] bacterium_MOT-104_nov_86.600% (SPN7)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	15.5	30.0
Duncaniella freteri_nov_93.699% (SPN72)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.5	4.0
Desulfovibrio legallii_nov_94.545% (SPN76)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	3.5	6.0
Muribaculaceae_[G-1] bacterium_MOT-129_nov_87.045% (SPN8)	1.0	1.0	1.0	482.0	963.0	1.0	1.0	1.0	1.0	1.0
Desulfonatronum lacustre_nov_77.130% (SPN92)	1.0	1.0	1.0	7.0	13.0	1.0	1.0	1.0	1.0	1.0
Duncaniella freteri_nov_90.303% (SPN95)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.5	4.0
Staphylococcus multispecies_spp12_3 (SPP12)	1.0	1.0	1.0	1005.5	2010.0	1.0	459.0	917.0	10789.5	20662.0
Staphylococcus multispecies_spp15_2 (SPP15)	1.0	1.0	1.0	11558.0	23115.0	1.0	1.0	1.0	109.0	217.0
Selenomonas multispecies_spp2_2 (SPP2)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.5	4.0
Psychrobacter multispecies_spp8_2 (SPP8)	1.0	1.0	1.0	1318.0	2635.0	1.0	1.0	1.0	1.0	1.0
Staphylococcus multispecies_sppn6_2_nov_95.093% (SPPN6)	1.0	1.0	1.0	3.0	5.0	1.0	1.0	1.0	1.0	1.0