Percentile	0.0	25.0	50.0	75.0	100.0	0.0	25.0	50.0	75.0	100.0
Group	Female Brain Genotype- SPM+ Treated	Female Brain Genotype- SPM+ Treated	Female Brain Genotype- SPM+ Treated	Female Brain Genotype- SPM+ Treated	Female Brain Genotype- SPM+ Treated	Female Ligature Genotype- SPM+ Treated	Female Ligature Genotype- SPM+ Treated	Female Ligature Genotype- SPM+ Treated	Female Ligature Genotype- SPM+ Treated	Female Ligature Genotype- SPM+ Treated
Porphyromonas gingivalis (SP1)	1.0	67.25	133.5	199.75	266.0	1.0	1.0	1.0	1.0	1.0
Prevotella oulorum (SP10)	1.0	466.5	932.0	1397.5	1863.0	1.0	1.0	1.0	1.0	1.0
Fusobacterium nucleatum_subsp._vincentii (SP102)	1.0	408.0	815.0	1222.0	1629.0	1.0	1.0	1.0	1.0	1.0
Brochothrix thermosphacta (SP11)	1.0	14723.0	29445.0	44167.0	58889.0	1.0	1.0	1.0	1.0	1.0
Lactobacillus johnsonii (SP110)	1.0	1.0	1.0	1.0	1.0	1.0	21.0	41.0	93.0	145.0
Mogibacterium timidum (SP119)	1.0	191.75	382.5	573.25	764.0	1.0	1.0	1.0	1.0	1.0
Psychrobacter cibarius (SP121)	1.0	12221.25	24441.5	36661.75	48882.0	1.0	1.0	1.0	1.0	1.0
Kocuria rhizophila (SP126)	1.0	539.0	1077.0	1615.0	2153.0	1.0	1.0	1.0	1.0	1.0
Streptococcus mitis (SP128)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	14.5	28.0
Pseudomonas fragi (SP129)	1.0	975.0	1949.0	2923.0	3897.0	1.0	1.0	1.0	1.0	1.0
Fusobacterium nucleatum (SP13)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	29.0	57.0
Phocaeicola sartorii (SP132)	1.0	1.0	1.0	1.0	1.0	392.0	477.0	562.0	9831.5	19101.0
Alloprevotella tannerae (SP138)	1.0	48.75	96.5	144.25	192.0	1.0	1.0	1.0	1.0	1.0
Bacteroidales_[G-2] bacterium HMT274 (SP139)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	4.0	7.0
Pseudomonas psychrophila (SP144)	1.0	31.75	62.5	93.25	124.0	1.0	1.0	1.0	1.0	1.0
Akkermansia muciniphila (SP159)	1.0	1.0	1.0	1.0	1.0	1.0	2.5	4.0	9.5	15.0
Carnobacterium gallinarum (SP163)	1.0	208.75	416.5	624.25	832.0	1.0	1.0	1.0	1.0	1.0
Klebsiella pneumoniae (SP17)	1.0	1.0	1.0	1.0	1.0	620.0	93676.0	186732.0	235103.5	283475.0
Enterobacter asburiae (SP173)	1.0	1.0	1.0	1.0	1.0	1.0	44.5	88.0	11318.5	22549.0
Ligilactobacillus murinus (SP18)	1.0	1.0	1.0	1.0	1.0	136.0	1096.5	2057.0	3464.5	4872.0
Cutibacterium granulosum (SP186)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	3.0	5.0
Actinomyces sp. HMT414 (SP187)	1.0	257.0	513.0	769.0	1025.0	1.0	1.0	1.0	1.0	1.0
Acinetobacter lwoffii (SP189)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	3.5	6.0
Erysipelotrichaceae_[G-1] bacterium_MOT-189 (SP19)	1.0	101.0	201.0	301.0	401.0	1.0	1.0	1.0	1.0	1.0
Vagococcus salmoninarum (SP192)	1.0	69.75	138.5	207.25	276.0	1.0	1.0	1.0	1.0	1.0
Bacteroides caccae (SP195)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	10.0	19.0
Peptostreptococcaceae_[XI][G-9] [Eubacterium]_brachy (SP197)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	4.5	8.0
Streptococcus oralis_subsp._tigurinus_clade_071 (SP205)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	3.0	5.0
Streptococcus downei (SP217)	1.0	116.0	231.0	346.0	461.0	1.0	1.0	1.0	1.0	1.0
Streptococcus chosunense (SP218)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	53.0	105.0
Curtobacterium pusillum (SP229)	1.0	210.5	420.0	629.5	839.0	1.0	1.0	1.0	1.0	1.0
Treponema sp. HMT234 (SP238)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	11.0	21.0
Cellvibrio ostraviensis (SP240)	1.0	30.0	59.0	88.0	117.0	1.0	1.0	1.0	1.0	1.0
Shigella sonnei (SP241)	1.0	115.0	229.0	343.0	457.0	1.0	1.0	1.0	8.0	15.0
Veillonella parvula (SP33)	1.0	378.75	756.5	1134.25	1512.0	1.0	1.0	1.0	29.0	57.0
Pseudomonas marginalis (SP36)	1.0	255.5	510.0	764.5	1019.0	1.0	1.0	1.0	1.0	1.0
Enterococcus faecalis (SP37)	1.0	1.0	1.0	1.0	1.0	18957.0	25112.5	31268.0	37890.0	44512.0
Cutibacterium acnes (SP41)	1.0	63.75	126.5	189.25	252.0	1.0	9.0	17.0	6470.5	12924.0
Acinetobacter johnsonii (SP42)	167.0	344.75	522.5	700.25	878.0	1.0	1.0	1.0	18.5	36.0
Pseudomonas weihenstephanensis (SP54)	1.0	3578.75	7156.5	10734.25	14312.0	1.0	1.0	1.0	1.0	1.0
Psychrobacter urativorans (SP56)	1.0	546.5	1092.0	1637.5	2183.0	1.0	1.0	1.0	1.0	1.0
Arthrobacter psychrolactophilus (SP60)	1.0	1008.0	2015.0	3022.0	4029.0	1.0	1.0	1.0	1.0	1.0
Enterobacter kobei (SP61)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	28.0	55.0
Limosilactobacillus reuteri (SP65)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	27.5	54.0
Enterobacter mori (SP7)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	84235.0	168469.0
Streptococcus thoraltensis (SP70)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	5.5	10.0
Porphyromonas catoniae (SP71)	1.0	357.0	713.0	1069.0	1425.0	1.0	1.0	1.0	1.0	1.0
Streptococcus danieliae (SP73)	1.0	1.0	1.0	1.0	1.0	1.0	50.5	100.0	139.0	178.0
Treponema denticola (SP74)	1.0	327.75	654.5	981.25	1308.0	1.0	1.0	1.0	1.0	1.0
Arthrobacter psychrochitiniphilus (SP76)	1.0	698.75	1396.5	2094.25	2792.0	1.0	1.0	1.0	1.0	1.0
Lautropia mirabilis (SP78)	1.0	304.0	607.0	910.0	1213.0	1.0	1.0	1.0	1.0	1.0
Proteus mirabilis (SP8)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	8.5	16.0
Fretibacterium sp. HMT362 (SP83)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	5.0	9.0
Psychrobacter glacincola (SP99)	1.0	158.5	316.0	473.5	631.0	1.0	1.0	1.0	1.0	1.0
Flavobacterium antarcticum_nov_96.660% (SPN101)	1.0	65.75	130.5	195.25	260.0	1.0	1.0	1.0	1.0	1.0
Faecalibaculum rodentium_nov_96.715% (SPN108)	1.0	1.0	1.0	1.0	1.0	1.0	1796.5	3592.0	4839.5	6087.0
Acinetobacter pragensis_nov_97.510% (SPN109)	1.0	59.25	117.5	175.75	234.0	1.0	1.0	1.0	1.0	1.0
Muribaculaceae_[G-2] bacterium_MOT-104_nov_90.600% (SPN117)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	43.5	86.0
Prevotella shahii_nov_87.602% (SPN118)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	37.5	74.0
Oscillospiraceae_[G-3] bacterium_MOT-150_nov_90.722% (SPN12)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	14.5	28.0
Duncaniella freteri_nov_89.113% (SPN120)	1.0	93.25	185.5	277.75	370.0	1.0	1.0	1.0	1.0	1.0
Bacteroides rodentium_nov_92.057% (SPN122)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	18.5	36.0
Longibaculum muris_nov_93.568% (SPN124)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	68.5	136.0
Duncaniella freteri_nov_89.718% (SPN127)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	59.5	118.0
Muribaculaceae_[G-2] bacterium_MOT-104_nov_88.978% (SPN13)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	14.5	28.0
Acinetobacter lwoffii_nov_96.289% (SPN15)	1.0	473.5	946.0	1418.5	1891.0	1.0	1.0	1.0	1.0	1.0
Actinomyces sp. HMT896 nov_96.586% (SPN18)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	12.5	24.0
Enterobacter mori_nov_97.951% (SPN2)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	13713.5	27426.0
Actinomyces israelii_nov_94.882% (SPN20)	1.0	406.75	812.5	1218.25	1624.0	1.0	1.0	1.0	1.0	1.0
Parasutterella excrementihominis_nov_94.578% (SPN24)	1.0	1.0	1.0	1.0	1.0	1.0	12.0	23.0	60.0	97.0
Duncaniella freteri_nov_92.915% (SPN4)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	24.5	48.0
Ligilactobacillus murinus_nov_96.477% (SPN63)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	7.0	13.0
Agathobaculum desmolans_nov_90.814% (SPN77)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	3.5	6.0
Duncaniella freteri_nov_93.509% (SPN79)	1.0	83.75	166.5	249.25	332.0	1.0	1.0	1.0	1.0	1.0
Muribaculaceae_[G-1] bacterium_MOT-129_nov_87.045% (SPN8)	1.0	541.75	1082.5	1623.25	2164.0	1.0	1.0	1.0	1.0	1.0
Methylococcus thermophilus_nov_81.186% (SPN83)	1.0	2.0	3.0	4.0	5.0	1.0	1.0	1.0	1.0	1.0
Lachnospiraceae_[G-6] bacterium_MOT-171_nov_94.770% (SPN9)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	19.0	37.0
Lysinibacillus pakistanensis_nov_80.483% (SPN98)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.5	4.0
Bacillus multispecies_spp11_2 (SPP11)	1.0	30.75	60.5	90.25	120.0	1.0	1.0	1.0	1.0	1.0
Staphylococcus multispecies_spp12_3 (SPP12)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	235.0	469.0
Pseudomonas multispecies_spp14_2 (SPP14)	1.0	3029.75	6058.5	9087.25	12116.0	1.0	1.0	1.0	1.0	1.0
Staphylococcus multispecies_spp15_2 (SPP15)	1.0	1.0	1.0	1.0	1.0	1.0	24.0	47.0	77.5	108.0
Pseudomonas multispecies_spp5_2 (SPP5)	1.0	30.75	60.5	90.25	120.0	1.0	1.0	1.0	1.0	1.0
Peptostreptococcaceae_[XI][G-4] multispecies_spp7_2 (SPP7)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	5.5	10.0
Psychrobacter multispecies_spp8_2 (SPP8)	1.0	25363.0	50725.0	76087.0	101449.0	1.0	1.0	1.0	1.0	1.0
Psychrobacter multispecies_spp9_2 (SPP9)	1.0	289.5	578.0	866.5	1155.0	1.0	1.0	1.0	1.0	1.0
Psychrobacter multispecies_sppn3_2_nov_97.119% (SPPN3)	1.0	2.75	4.5	6.25	8.0	1.0	1.0	1.0	1.0	1.0
Faecalicatena multispecies_sppn7_2_nov_91.858% (SPPN7)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	38.5	76.0