Percentile	0.0	25.0	50.0	75.0	100.0	0.0	25.0	50.0	75.0	100.0
Group	Male Brain Genotype+ SPM- Nontreated	Male Brain Genotype+ SPM- Nontreated	Male Brain Genotype+ SPM- Nontreated	Male Brain Genotype+ SPM- Nontreated	Male Brain Genotype+ SPM- Nontreated	Male Ligature Genotype+ SPM- Nontreated	Male Ligature Genotype+ SPM- Nontreated	Male Ligature Genotype+ SPM- Nontreated	Male Ligature Genotype+ SPM- Nontreated	Male Ligature Genotype+ SPM- Nontreated
Porphyromonas gingivalis (SP1)	1.0	1.0	1.0	261.5	522.0	1.0	3.5	6.0	24.5	43.0
Lactobacillus johnsonii (SP110)	1.0	1.0	1.0	1.0	1.0	1.0	2.5	4.0	11.5	19.0
Staphylococcus ureilyticus (SP120)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	115.0	229.0
Saccharibacteria_(TM7)_[G-1] bacterium HMT349 (SP127)	1.0	1.0	1.0	1015.5	2030.0	1.0	1.0	1.0	1.0	1.0
Fusobacterium nucleatum (SP13)	1.0	1.0	1.0	786.0	1571.0	1.0	1.0	1.0	4.5	8.0
Jeotgalicoccus halotolerans (SP131)	1.0	1.0	1.0	240.5	480.0	1.0	2.0	3.0	4.0	5.0
Phocaeicola sartorii (SP132)	1.0	1.0	1.0	1.0	1.0	1.0	1880.5	3760.0	7439.5	11119.0
Citrobacter koseri (SP142)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	438.0	875.0
Triticum aestivum (SP146)	1.0	1.0	1.0	1.0	1.0	1.0	3.5	6.0	6.5	7.0
Acinetobacter radioresistens (SP148)	1.0	1.0	1.0	136.5	272.0	1.0	1.0	1.0	2.5	4.0
Campylobacter rectus (SP149)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	4.0	7.0
Enterobacter hormaechei (SP15)	1.0	1.0	1.0	483.0	965.0	1.0	1.0	1.0	39102.0	78203.0
Klebsiella pneumoniae (SP17)	1.0	1.0	1.0	2033.5	4066.0	81404.0	118272.0	155140.0	177471.0	199802.0
Prevotella nigrescens (SP172)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.5	4.0
Streptococcus salivarius (SP174)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	4.0	7.0
Ligilactobacillus murinus (SP18)	1.0	1.0	1.0	1.0	1.0	113.0	4897.0	9681.0	13571.0	17461.0
Fusobacterium sp. HMT203 (SP193)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	7.0	13.0
Pseudoramibacter alactolyticus (SP224)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	3.0	5.0
Devosia insulae (SP227)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	3.5	6.0
Tannerella sp. HMT808 (SP24)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	4.0	7.0
Sphingomonas oligophenolica (SP245)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	6.0	11.0
Prevotella saccharolytica (SP29)	1.0	1.0	1.0	559.5	1118.0	1.0	1.0	1.0	1.0	1.0
Prevotella sp. HMT317 (SP3)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	4.0	7.0
Sphingomonas leidyi (SP30)	1.0	1.0	1.0	173.5	346.0	1.0	1.0	1.0	1.0	1.0
Bacteroidetes_[G-3] bacterium HMT280 (SP31)	1.0	1.0	1.0	301.0	601.0	1.0	1.0	1.0	1.0	1.0
Filifactor alocis (SP32)	1.0	1.0	1.0	785.0	1569.0	1.0	1.0	1.0	1.0	1.0
Bacillus subtilis (SP35)	1.0	1.0	1.0	87.5	174.0	1.0	1.0	1.0	1.0	1.0
Enterococcus faecalis (SP37)	1.0	1.0	1.0	351.5	702.0	12.0	12378.5	24745.0	35523.5	46302.0
Faecalibaculum rodentium (SP39)	1.0	1.0	1.0	1.0	1.0	1.0	12.5	24.0	24.0	24.0
Bulleidia extructa (SP4)	1.0	1.0	1.0	5850.0	11699.0	1.0	1.0	1.0	1.0	1.0
Cutibacterium acnes (SP41)	1.0	1.0	1.0	1.0	1.0	1.0	16.5	32.0	546.0	1060.0
Acinetobacter johnsonii (SP42)	1.0	709.5	1418.0	1611.0	1804.0	1.0	1.0	1.0	4.0	7.0
Prevotella jejuni (SP57)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	5.0	9.0
Actinidia eriantha (SP64)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	18.0	35.0
Limosilactobacillus reuteri (SP65)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	8.5	16.0
Treponema sp. HMT237 (SP66)	1.0	1.0	1.0	197.5	394.0	1.0	1.0	1.0	1.0	1.0
Corynebacterium mastitidis (SP67)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	34.5	68.0
Mammaliicoccus lentus (SP68)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	127.5	254.0
Neisseriaceae_[G-1] bacterium_MOT-031 (SP69)	1.0	1.0	1.0	1.0	1.0	26.0	559.0	1092.0	2383.5	3675.0
Streptococcus thoraltensis (SP70)	1.0	1.0	1.0	104296.5	208592.0	139.0	17384.0	34629.0	45754.5	56880.0
Streptococcus danieliae (SP73)	1.0	1.0	1.0	1.0	1.0	79.0	86.5	94.0	298.5	503.0
Streptococcus oralis_subsp._tigurinus_clade_070 (SP79)	1.0	1.0	1.0	129.0	257.0	1.0	1.0	1.0	1.0	1.0
Proteus mirabilis (SP8)	1.0	1.0	1.0	671.0	1341.0	1.0	48.5	96.0	291.0	486.0
Prevotella oris (SP95)	1.0	1.0	1.0	1433.5	2866.0	1.0	1.0	1.0	1.0	1.0
Veillonellaceae_[G-1] bacterium HMT135 (SP96)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	5.0	9.0
Duncaniella freteri_nov_89.775% (SPN10)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	3.0	5.0
Mycolicibacillus trivialis_nov_84.855% (SPN107)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.0	3.0
Raoultibacter massiliensis_nov_88.312% (SPN115)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.0	3.0
Muribaculaceae_[G-2] bacterium_MOT-104_nov_90.600% (SPN117)	1.0	1.0	1.0	1.0	1.0	1.0	2.5	4.0	8.0	12.0
Prevotella shahii_nov_87.602% (SPN118)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	3.5	6.0
Duncaniella freteri_nov_89.718% (SPN127)	1.0	365.0	729.0	730.0	731.0	1.0	1.0	1.0	1.0	1.0
Duncaniella freteri_nov_91.429% (SPN128)	1.0	1.0	1.0	60.0	119.0	1.0	1.0	1.0	1.0	1.0
Muribaculaceae_[G-1] bacterium_MOT-129_nov_85.887% (SPN131)	1.0	1.0	1.0	99.0	197.0	1.0	1.0	1.0	1.0	1.0
Duncaniella freteri_nov_90.612% (SPN132)	1.0	1.0	1.0	194.0	387.0	1.0	1.0	1.0	12.5	24.0
Alloprevotella sp. HMT473 nov_89.366% (SPN134)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	13.0	25.0
Parasutterella excrementihominis_nov_94.578% (SPN24)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	302.0	603.0
Duncaniella freteri_nov_93.293% (SPN35)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	6.0	11.0
Muribaculaceae_[G-1] bacterium_MOT-129_nov_83.636% (SPN5)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	5.5	10.0
Culturomica massiliensis_nov_89.613% (SPN51)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.0	3.0
Streptococcus azizii_nov_95.171% (SPN52)	1.0	1.0	1.0	1.0	1.0	1.0	880.5	1760.0	6240.5	10721.0
Lacrimispora xylanolytica_nov_92.050% (SPN61)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	4.5	8.0
Muribaculaceae_[G-2] bacterium_MOT-104_nov_86.600% (SPN7)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.5	4.0
Duncaniella freteri_nov_93.699% (SPN72)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	4.0	7.0
Peptococcus sp. HMT167 nov_97.642% (SPN73)	1.0	1.0	1.0	206.5	412.0	1.0	1.0	1.0	1.0	1.0
Companilactobacillus mindensis_nov_85.039% (SPN82)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	7.0	13.0
Ihubacter massiliensis_nov_94.572% (SPN89)	1.0	1.0	1.0	154.0	307.0	1.0	1.0	1.0	1.0	1.0
Enterococcus faecium_nov_88.222% (SPN99)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.5	4.0
Veillonella multispecies_spp10_2 (SPP10)	1.0	1.0	1.0	1301.0	2601.0	1.0	1.0	1.0	2.5	4.0
Staphylococcus multispecies_spp12_3 (SPP12)	1.0	1.0	1.0	239.0	477.0	1.0	1.0	1.0	86.0	171.0
Staphylococcus multispecies_spp15_2 (SPP15)	1.0	1.0	1.0	1.0	1.0	11.0	20.0	29.0	30.5	32.0
Acinetobacter multispecies_spp6_2 (SPP6)	1.0	1.0	1.0	962.5	1924.0	1.0	1.0	1.0	1.0	1.0
