Percentile	0.0	25.0	50.0	75.0	100.0	0.0	25.0	50.0	75.0	100.0
Group	Female Brain Genotype+ SPM+ Treated	Female Brain Genotype+ SPM+ Treated	Female Brain Genotype+ SPM+ Treated	Female Brain Genotype+ SPM+ Treated	Female Brain Genotype+ SPM+ Treated	Female Ligature Genotype+ SPM+ Treated	Female Ligature Genotype+ SPM+ Treated	Female Ligature Genotype+ SPM+ Treated	Female Ligature Genotype+ SPM+ Treated	Female Ligature Genotype+ SPM+ Treated
Porphyromonas gingivalis (SP1)	1.0	1.0	1.0	4594.5	9188.0	1.0	1.0	1.0	1.0	1.0
Enterococcus gallinarum (SP100)	1.0	1.0	1.0	1.0	1.0	1.0	3.0	5.0	8.0	11.0
Enterobacter cancerogenus (SP103)	1.0	1.0	1.0	647.0	1293.0	1.0	1.0	1.0	32.0	63.0
Brochothrix thermosphacta (SP11)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.0	3.0
Tannerella forsythia (SP112)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	4.0	7.0
Peptostreptococcus stomatis (SP117)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	3.0	5.0
Mogibacterium timidum (SP119)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	4.5	8.0
Leptotrichia shahii (SP122)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	3.5	6.0
Fusobacterium nucleatum (SP13)	1.0	1.0	1.0	876.0	1751.0	1.0	1.0	1.0	3.0	5.0
Jeotgalicoccus halotolerans (SP131)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	6.5	12.0
Phocaeicola sartorii (SP132)	1.0	1.0	1.0	2660.0	5319.0	1.0	41.5	82.0	833.5	1585.0
Shigella boydii (SP135)	1.0	1.0	1.0	25.5	50.0	1.0	1.0	1.0	1.0	1.0
Mycoplasma faucium (SP137)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.5	4.0
Duncaniella freteri (SP14)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	6.0	11.0
Citrobacter koseri (SP142)	1.0	1.0	1.0	1340.5	2680.0	1.0	1.0	1.0	1.0	1.0
Chryseobacterium gambrini (SP143)	1.0	1.0	1.0	5637.5	11274.0	1.0	1.0	1.0	1.0	1.0
Enterobacter hormaechei (SP15)	1.0	1285.0	2569.0	14103.5	25638.0	1.0	15.0	29.0	97.0	165.0
Dialister invisus (SP152)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.0	3.0
Prevotella salivae (SP153)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	6.0	11.0
Akkermansia muciniphila (SP159)	1.0	1.0	1.0	7317.0	14633.0	1.0	1.0	1.0	1.0	1.0
Adlercreutzia mucosicola (SP16)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	32.0	63.0
Halopseudomonas formosensis (SP164)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.0	3.0
Lentilactobacillus kisonensis (SP165)	1.0	1.0	1.0	1330.5	2660.0	1.0	1.0	1.0	1.0	1.0
Campylobacter concisus (SP167)	1.0	1.0	1.0	1399.0	2797.0	1.0	1.0	1.0	1.0	1.0
Scardovia wiggsiae (SP168)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	3.5	6.0
Klebsiella pneumoniae (SP17)	1.0	9656.5	19312.0	58510.0	97708.0	90.0	3993.0	7896.0	87021.0	166146.0
Enterobacter asburiae (SP173)	1.0	1.0	1.0	1.0	1.0	1.0	10892.0	21783.0	21875.0	21967.0
Ligilactobacillus murinus (SP18)	1.0	1.0	1.0	4549.5	9098.0	1435.0	3290.0	5145.0	16879.0	28613.0
Aerococcus urinaeequi (SP180)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	18.5	36.0
Erysipelotrichaceae_[G-1] bacterium_MOT-189 (SP19)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	9.0	17.0
Staphylococcus warneri (SP191)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	33.0	65.0
Fusobacterium sp. HMT203 (SP193)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	4.5	8.0
Bacteroides caccae (SP195)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	351.5	702.0
Kosakonia sacchari (SP20)	1.0	1.0	1.0	2478.0	4955.0	1.0	1.0	1.0	1.0	1.0
Actinomyces sp. HMT897 (SP208)	1.0	1.0	1.0	3246.5	6492.0	1.0	1.0	1.0	1.0	1.0
Selenomonas sp. HMT137 (SP209)	1.0	1.0	1.0	5112.0	10223.0	1.0	1.0	1.0	1.0	1.0
Actinomyces dentalis (SP216)	1.0	1.0	1.0	2064.0	4127.0	1.0	1.0	1.0	1.0	1.0
Bacteroidetes_[G-3] bacterium HMT365 (SP220)	1.0	1.0	1.0	2665.0	5329.0	1.0	1.0	1.0	1.0	1.0
Deinococcus radiodurans (SP226)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	5.0	9.0
Streptococcus australis (SP23)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	3.5	6.0
Bifidobacterium pseudolongum (SP230)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	157.5	314.0
Enterobacter cloacae (SP28)	1.0	1.0	1.0	2305.0	4609.0	1.0	1.0	1.0	70.5	140.0
Sphingomonas leidyi (SP30)	1.0	1.0	1.0	67491.5	134982.0	1.0	1.0	1.0	1.0	1.0
Bacillus subtilis (SP35)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	5.0	9.0
Enterococcus faecalis (SP37)	1.0	1.0	1.0	1.0	1.0	31174.0	35009.0	38844.0	45890.5	52937.0
Cutibacterium acnes (SP41)	1.0	1.0	1.0	109844.0	219687.0	7.0	10.0	13.0	109.0	205.0
Porphyromonas endodontalis (SP52)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	3.0	5.0
Pseudomonas weihenstephanensis (SP54)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.0	3.0
Enterobacter mori (SP7)	1.0	1.0	1.0	1.0	1.0	1.0	79988.0	159975.0	160673.5	161372.0
Streptococcus thoraltensis (SP70)	1.0	1.0	1.0	1.0	1.0	1.0	17.0	33.0	291.5	550.0
Streptococcus danieliae (SP73)	1.0	1.0	1.0	1.0	1.0	293.0	823.0	1353.0	1426.5	1500.0
Neisseria bacilliformis (SP77)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	3.0	5.0
Proteus mirabilis (SP8)	1.0	4963.5	9926.0	66700.5	123475.0	1.0	20.5	40.0	1285.0	2530.0
Streptococcus cristatus_clade_578 (SP82)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	6.0	11.0
Fretibacterium sp. HMT362 (SP83)	1.0	1.0	1.0	1.0	1.0	1.0	4.0	7.0	10.0	13.0
Mammaliicoccus sciuri (SP85)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	15.0	29.0
Selenomonas noxia (SP89)	1.0	1.0	1.0	6915.5	13830.0	1.0	1.0	1.0	1.0	1.0
Porphyromonas pasteri (SP92)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	4.0	7.0
Gemella haemolysans (SP97)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	3.0	5.0
Fudania jinshanensis_nov_84.187% (SPN104)	1.0	1.0	1.0	2.5	4.0	1.0	1.0	1.0	1.0	1.0
Sporobacter termitidis_nov_87.580% (SPN105)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.0	3.0
Triticum aestivum_nov_97.931% (SPN106)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.0	3.0
Faecalibaculum rodentium_nov_96.715% (SPN108)	1.0	1.0	1.0	1.0	1.0	1.0	16.5	32.0	9745.0	19458.0
Prevotella shahii_nov_87.602% (SPN118)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.0	3.0
Adlercreutzia muris_nov_91.845% (SPN119)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	93.5	186.0
Duncaniella freteri_nov_89.113% (SPN120)	1.0	1.0	1.0	12593.5	25186.0	1.0	2.5	4.0	4.5	5.0
Chryseobacterium yeoncheonense_nov_97.484% (SPN121)	1.0	1.0	1.0	78.0	155.0	1.0	1.0	1.0	1.0	1.0
Duncaniella freteri_nov_89.718% (SPN127)	1.0	1.0	1.0	5818.0	11635.0	1.0	1.0	1.0	1.0	1.0
Oscillospiraceae_[G-4] bacterium_MOT-151_nov_94.387% (SPN130)	1.0	1.0	1.0	5592.0	11183.0	1.0	1.0	1.0	1.0	1.0
Muribaculaceae_[G-1] bacterium_MOT-129_nov_85.887% (SPN131)	1.0	1.0	1.0	4982.5	9964.0	1.0	1.0	1.0	1.0	1.0
Duncaniella freteri_nov_90.612% (SPN132)	1.0	1.0	1.0	4242.5	8484.0	1.0	1.0	1.0	1.0	1.0
Duncaniella freteri_nov_88.800% (SPN133)	1.0	1.0	1.0	4820.0	9639.0	1.0	1.0	1.0	1.0	1.0
Enterobacter mori_nov_97.951% (SPN2)	1.0	1.0	1.0	1.0	1.0	1.0	13551.5	27102.0	27165.5	27229.0
Parasutterella excrementihominis_nov_94.578% (SPN24)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	11.5	22.0
Duncaniella freteri_nov_93.293% (SPN31)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	6.5	12.0
Adlercreutzia caecimuris_nov_92.688% (SPN32)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	9.0	17.0
Duncaniella freteri_nov_92.915% (SPN4)	1.0	1.0	1.0	3205.0	6409.0	1.0	1.0	1.0	5.5	10.0
Selenomonas sp. HMT126 nov_89.450% (SPN40)	1.0	1.0	1.0	7.5	14.0	1.0	1.0	1.0	1.0	1.0
Oscillospiraceae_[G-2] bacterium_MOT-149_nov_93.319% (SPN56)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	3.0	5.0
Christensenella hongkongensis_nov_86.308% (SPN59)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	4.5	8.0
Rubritalea tangerina_nov_82.960% (SPN60)	1.0	1.0	1.0	4.5	8.0	1.0	1.0	1.0	1.0	1.0
Porphyromonas gingivalis_nov_95.688% (SPN62)	1.0	1.0	1.0	4.5	8.0	1.0	1.0	1.0	1.0	1.0
Grimontia marina_nov_87.470% (SPN81)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	3.0	5.0
Actinidia eriantha_nov_97.931% (SPN90)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	3.0	5.0
Bacillus multispecies_spp11_2 (SPP11)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	3.0	5.0
Staphylococcus multispecies_spp12_3 (SPP12)	1.0	1.0	1.0	1.0	1.0	1.0	3.0	5.0	14055.5	28106.0
Staphylococcus multispecies_spp13_2 (SPP13)	1.0	1.0	1.0	19541.0	39081.0	1.0	1.0	1.0	1.0	1.0
Staphylococcus multispecies_spp15_2 (SPP15)	1.0	1.0	1.0	1.0	1.0	7.0	8.0	9.0	18.5	28.0
Psychrobacter multispecies_spp3_4 (SPP3)	1.0	1.0	1.0	14.5	28.0	1.0	1.0	1.0	1.0	1.0
Psychrobacter multispecies_spp8_2 (SPP8)	1.0	1.0	1.0	7941.0	15881.0	1.0	1.0	1.0	1.0	1.0
Porphyromonas multispecies_sppn1_2_nov_89.959% (SPPN1)	1.0	1.0	1.0	10.5	20.0	1.0	1.0	1.0	1.0	1.0
Staphylococcus multispecies_sppn5_2_nov_96.566% (SPPN5)	1.0	1.0	1.0	4.0	7.0	1.0	1.0	1.0	1.0	1.0