Percentile	0.0	25.0	50.0	75.0	100.0	0.0	25.0	50.0	75.0	100.0
Group	Day 15 Microbiome Only	Day 15 Microbiome Only	Day 15 Microbiome Only	Day 15 Microbiome Only	Day 15 Microbiome Only	Probiotics 2 Day 0	Probiotics 2 Day 0	Probiotics 2 Day 0	Probiotics 2 Day 0	Probiotics 2 Day 0
Selenomonas sputigena (SP10)	1.0	1.0	1.0	1.0	1.0	118.0	122.0	142.0	177.0	206.0
Bergeyella sp. HMT322 (SP100)	1.0	1.0	1.0	1.0	1.0	72.0	87.0	121.0	124.0	168.0
Capnocytophaga sputigena (SP103)	5.0	5.5	6.0	6.5	7.0	311.0	368.0	469.0	476.0	507.0
Streptococcus oralis_subsp._tigurinus_clade_070 (SP105)	3786.0	4248.25	4710.5	5172.75	5635.0	604.0	685.0	707.0	959.0	1713.0
Streptococcus cristatus_clade_578 (SP107)	889.0	903.75	918.5	933.25	948.0	1175.0	1247.0	1347.0	1503.0	2157.0
Fretibacterium sp. HMT359 (SP108)	1.0	1.0	1.0	1.0	1.0	215.0	244.0	478.0	504.0	515.0
Leptotrichia sp. HMT417 (SP11)	1.0	1.0	1.0	1.0	1.0	366.0	497.0	568.0	661.0	1186.0
Actinomyces sp. HMT896 (SP110)	1.0	1.0	1.0	1.0	1.0	249.0	302.0	393.0	464.0	469.0
Porphyromonas gingivalis (SP111)	2311.0	2718.5	3126.0	3533.5	3941.0	353.0	365.0	580.0	1017.0	2919.0
Dialister invisus (SP112)	22.0	23.0	24.0	25.0	26.0	333.0	356.0	370.0	440.0	838.0
Oribacterium sp. HMT078 (SP113)	1.0	1.0	1.0	1.0	1.0	121.0	183.0	190.0	220.0	254.0
Capnocytophaga granulosa (SP114)	1.0	1.0	1.0	1.0	1.0	693.0	702.0	704.0	832.0	833.0
Actinomyces sp. HMT525 (SP118)	1.0	1.0	1.0	1.0	1.0	416.0	517.0	545.0	619.0	1066.0
Slackia exigua (SP119)	299.0	327.75	356.5	385.25	414.0	30.0	34.0	70.0	74.0	105.0
Peptostreptococcaceae_[XI][G-7] [Eubacterium]_yurii_subsps._yurii_&_margaretiae (SP12)	775.0	896.75	1018.5	1140.25	1262.0	149.0	154.0	189.0	210.0	216.0
Fusobacterium periodonticum (SP121)	31.0	33.25	35.5	37.75	40.0	68.0	128.0	134.0	201.0	472.0
Gemella morbillorum (SP123)	642.0	679.75	717.5	755.25	793.0	1486.0	1780.0	1868.0	1907.0	2353.0
Aggregatibacter sp. HMT512 (SP124)	156.0	196.0	236.0	276.0	316.0	1.0	1.0	1.0	25.0	26.0
Arachnia propionica (SP125)	1.0	2.5	4.0	5.5	7.0	715.0	799.0	860.0	1048.0	1628.0
Schaalia sp. HMT180 (SP129)	72.0	72.5	73.0	73.5	74.0	189.0	255.0	256.0	272.0	347.0
Prevotella sp. HMT317 (SP13)	1.0	1.25	1.5	1.75	2.0	1738.0	1741.0	1861.0	1865.0	2963.0
Streptococcus sp. HMT423 (SP130)	2169.0	2363.25	2557.5	2751.75	2946.0	2419.0	2679.0	2744.0	3327.0	3505.0
Streptococcus salivarius (SP131)	1583.0	1749.5	1916.0	2082.5	2249.0	10.0	14.0	15.0	20.0	21.0
Campylobacter gracilis (SP136)	1.0	1.0	1.0	1.0	1.0	515.0	540.0	558.0	558.0	793.0
Actinomyces sp. HMT169 (SP138)	1.0	1.0	1.0	1.0	1.0	357.0	396.0	457.0	461.0	510.0
Actinomyces sp. HMT175 (SP139)	1.0	1.0	1.0	1.0	1.0	152.0	187.0	194.0	299.0	535.0
Streptococcus oralis (SP140)	6685.0	6958.75	7232.5	7506.25	7780.0	1472.0	1509.0	1566.0	1593.0	1906.0
Ottowia sp. HMT894 (SP141)	2150.0	3112.5	4075.0	5037.5	6000.0	82.0	108.0	136.0	140.0	273.0
Tannerella forsythia (SP142)	168.0	220.25	272.5	324.75	377.0	546.0	1036.0	1134.0	1232.0	1541.0
Olsenella sp. HMT807 (SP144)	1.0	1.0	1.0	1.0	1.0	639.0	707.0	734.0	771.0	804.0
Leptotrichia hofstadii (SP145)	1.0	1.0	1.0	1.0	1.0	294.0	325.0	406.0	410.0	479.0
Porphyromonas endodontalis (SP149)	75.0	83.5	92.0	100.5	109.0	219.0	264.0	294.0	310.0	508.0
Prevotella oris (SP154)	1.0	3.25	5.5	7.75	10.0	349.0	509.0	615.0	633.0	824.0
Fretibacterium fastidiosum (SP162)	13.0	15.0	17.0	19.0	21.0	127.0	139.0	262.0	306.0	499.0
Solobacterium moorei (SP164)	1084.0	1220.0	1356.0	1492.0	1628.0	90.0	97.0	155.0	197.0	212.0
Saccharibacteria_(TM7)_[G-1] bacterium HMT348 (SP165)	1.0	1.0	1.0	1.0	1.0	158.0	209.0	227.0	243.0	411.0
Peptoanaerobacter [Eubacterium] yurii (SP167)	1.0	1.0	1.0	1.0	1.0	58.0	71.0	87.0	143.0	311.0
Porphyromonas pasteri (SP17)	3.0	4.0	5.0	6.0	7.0	493.0	744.0	866.0	954.0	1040.0
Prevotella sp. HMT300 (SP172)	18.0	28.75	39.5	50.25	61.0	198.0	228.0	243.0	246.0	359.0
Leptotrichia wadei (SP176)	1.0	1.0	1.0	1.0	1.0	426.0	470.0	805.0	823.0	905.0
Selenomonas noxia (SP179)	1.0	1.0	1.0	1.0	1.0	171.0	314.0	336.0	358.0	383.0
Porphyromonas catoniae (SP18)	21.0	21.25	21.5	21.75	22.0	222.0	333.0	379.0	399.0	457.0
Prevotella denticola (SP184)	1.0	1.0	1.0	1.0	1.0	188.0	195.0	214.0	259.0	306.0
Eikenella corrodens (SP185)	52.0	65.5	79.0	92.5	106.0	349.0	509.0	616.0	754.0	901.0
Actinomyces johnsonii (SP189)	1.0	1.0	1.0	1.0	1.0	435.0	627.0	786.0	983.0	1010.0
Prevotella melaninogenica (SP19)	1.0	1.0	1.0	1.0	1.0	123.0	159.0	211.0	225.0	255.0
Abiotrophia defectiva (SP190)	14.0	18.0	22.0	26.0	30.0	383.0	446.0	499.0	513.0	543.0
Streptococcus chosunense (SP191)	622.0	760.75	899.5	1038.25	1177.0	486.0	658.0	666.0	675.0	685.0
Streptococcus oralis_subsp._dentisani_clade_058 (SP192)	561.0	622.25	683.5	744.75	806.0	408.0	556.0	670.0	692.0	787.0
Schaalia odontolytica (SP198)	19.0	23.25	27.5	31.75	36.0	189.0	228.0	247.0	252.0	309.0
Veillonella dispar (SP20)	158.0	168.5	179.0	189.5	200.0	73.0	87.0	119.0	120.0	127.0
Rothia aeria (SP205)	1.0	1.0	1.0	1.0	1.0	512.0	568.0	644.0	660.0	920.0
Bacteroides heparinolyticus (SP208)	1444.0	1459.25	1474.5	1489.75	1505.0	1.0	1.0	1.0	1.0	4.0
Parvimonas micra (SP214)	230.0	235.5	241.0	246.5	252.0	777.0	946.0	1029.0	1485.0	1535.0
Streptococcus mitis (SP217)	1.0	1.0	1.0	1.0	1.0	130.0	140.0	153.0	158.0	205.0
Saccharibacteria_(TM7)_[G-1] bacterium HMT349 (SP218)	1.0	1.0	1.0	1.0	1.0	142.0	143.0	159.0	240.0	538.0
Lachnospiraceae_[G-3] bacterium HMT100 (SP222)	1.0	1.0	1.0	1.0	1.0	484.0	526.0	566.0	575.0	824.0
Actinomyces massiliensis (SP229)	1.0	1.0	1.0	1.0	1.0	730.0	735.0	896.0	914.0	962.0
Fretibacterium sp. HMT360 (SP23)	155.0	168.0	181.0	194.0	207.0	335.0	341.0	559.0	566.0	703.0
Schaalia sp. HMT877 (SP230)	1.0	1.0	1.0	1.0	1.0	243.0	267.0	269.0	305.0	404.0
Filifactor alocis (SP234)	154.0	180.75	207.5	234.25	261.0	171.0	276.0	293.0	357.0	823.0
Saccharibacteria_(TM7)_[G-1] bacterium HMT346 (SP240)	1.0	1.0	1.0	1.0	1.0	448.0	643.0	764.0	768.0	777.0
Lachnoanaerobaculum saburreum (SP241)	1.0	1.0	1.0	1.0	1.0	238.0	255.0	317.0	333.0	359.0
Schaalia cardiffensis (SP247)	997.0	1476.5	1956.0	2435.5	2915.0	1.0	32.0	44.0	51.0	75.0
Leptotrichia sp. HMT212 (SP25)	1.0	1.0	1.0	1.0	1.0	267.0	306.0	394.0	430.0	472.0
Streptococcus constellatus (SP252)	117.0	118.5	120.0	121.5	123.0	209.0	296.0	341.0	412.0	594.0
Schaalia sp. HMT178 (SP255)	1.0	2.0	3.0	4.0	5.0	285.0	316.0	357.0	410.0	545.0
Peptostreptococcus stomatis (SP256)	3853.0	3855.0	3857.0	3859.0	3861.0	140.0	159.0	195.0	195.0	250.0
Aggregatibacter segnis (SP26)	481.0	503.75	526.5	549.25	572.0	170.0	236.0	266.0	311.0	536.0
Cardiobacterium hominis (SP261)	1.0	1.0	1.0	1.0	1.0	158.0	181.0	224.0	285.0	285.0
Streptococcus sp. HMT064 (SP262)	917.0	1081.75	1246.5	1411.25	1576.0	697.0	724.0	742.0	798.0	918.0
Gemella haemolysans (SP265)	7.0	7.0	7.0	7.0	7.0	64.0	65.0	71.0	75.0	81.0
Prevotella buccae (SP269)	210.0	212.25	214.5	216.75	219.0	1.0	1.0	20.0	40.0	51.0
Streptococcus anginosus (SP271)	85.0	86.5	88.0	89.5	91.0	22.0	28.0	31.0	35.0	41.0
Saccharibacteria_(TM7)_[G-1] bacterium HMT957 (SP277)	1.0	3.75	6.5	9.25	12.0	42.0	80.0	88.0	92.0	93.0
Serratia marcescens (SP278)	10414.0	11246.75	12079.5	12912.25	13745.0	1.0	1.0	1.0	1.0	1.0
Neisseria flava (SP28)	747.0	774.5	802.0	829.5	857.0	552.0	605.0	706.0	944.0	1083.0
Peptostreptococcaceae_[XI][G-1] [Eubacterium]_infirmum (SP284)	612.0	632.25	652.5	672.75	693.0	25.0	42.0	46.0	54.0	105.0
Neisseria subflava (SP286)	2271.0	2309.25	2347.5	2385.75	2424.0	293.0	311.0	380.0	569.0	579.0
Saccharibacteria_(TM7)_[G-5] bacterium HMT356 (SP287)	1.0	1.0	1.0	1.0	1.0	32.0	33.0	33.0	75.0	128.0
Streptococcus gordonii (SP289)	1010.0	1217.75	1425.5	1633.25	1841.0	1741.0	2053.0	2074.0	2157.0	2517.0
Enterobacter cloacae (SP29)	613.0	1079.0	1545.0	2011.0	2477.0	1.0	1.0	1.0	1.0	1.0
Neisseria flavescens (SP294)	10.0	10.25	10.5	10.75	11.0	103.0	108.0	124.0	152.0	1326.0
Saccharibacteria_(TM7)_[G-4] bacterium HMT355 (SP295)	66.0	77.0	88.0	99.0	110.0	1.0	1.0	1.0	1.0	11.0
Neisseria sicca (SP296)	288.0	289.0	290.0	291.0	292.0	192.0	209.0	210.0	369.0	383.0
Cardiobacterium valvarum (SP297)	1.0	1.0	1.0	1.0	1.0	335.0	339.0	379.0	397.0	575.0
Fusobacterium nucleatum_subsp._animalis (SP3)	1.0	1.0	1.0	1.0	1.0	126.0	159.0	241.0	333.0	349.0
Capnocytophaga gingivalis (SP30)	1.0	1.0	1.0	1.0	1.0	304.0	318.0	321.0	351.0	426.0
Saccharibacteria_(TM7)_[G-6] bacterium HMT870 (SP301)	1.0	1.0	1.0	1.0	1.0	11.0	18.0	27.0	30.0	31.0
Parvimonas sp. HMT110 (SP310)	1.0	1.0	1.0	1.0	1.0	29.0	76.0	118.0	144.0	159.0
Peptidiphaga gingivicola (SP313)	1.0	1.0	1.0	1.0	1.0	170.0	212.0	225.0	228.0	439.0
Alloprevotella tannerae (SP32)	14.0	15.5	17.0	18.5	20.0	918.0	995.0	1075.0	1156.0	1554.0
Streptococcus oralis_subsp._tigurinus_clade_071 (SP330)	310.0	312.5	315.0	317.5	320.0	40.0	54.0	79.0	99.0	121.0
Peptidiphaga sp. HMT183 (SP332)	1.0	1.0	1.0	1.0	1.0	747.0	988.0	1247.0	2346.0	3007.0
Streptococcus sp. HMT056 (SP334)	1.0	2.25	3.5	4.75	6.0	100.0	131.0	148.0	182.0	190.0
Bacteroidales_[G-2] bacterium HMT274 (SP34)	102.0	116.0	130.0	144.0	158.0	933.0	938.0	1009.0	1742.0	2537.0
Leptotrichia sp. HMT392 (SP35)	1.0	1.0	1.0	1.0	1.0	763.0	839.0	960.0	975.0	977.0
Peptostreptococcaceae_[XI][G-9] [Eubacterium]_brachy (SP359)	16.0	18.5	21.0	23.5	26.0	217.0	252.0	345.0	402.0	421.0
Prevotella nigrescens (SP36)	90.0	98.5	107.0	115.5	124.0	970.0	1066.0	1208.0	1691.0	2086.0
Rothia dentocariosa (SP366)	1.0	2.25	3.5	4.75	6.0	780.0	798.0	815.0	945.0	984.0
Actinomyces sp. HMT414 (SP368)	1.0	1.0	1.0	1.0	1.0	214.0	233.0	286.0	319.0	825.0
Centipeda periodontii (SP37)	18.0	18.75	19.5	20.25	21.0	83.0	88.0	99.0	124.0	730.0
Actinomyces naeslundii (SP38)	1.0	2.5	4.0	5.5	7.0	1707.0	1735.0	1828.0	2026.0	2093.0
Streptococcus intermedius (SP384)	1.0	1.0	1.0	1.0	1.0	71.0	159.0	176.0	196.0	253.0
Peptoanaerobacter stomatis (SP387)	4.0	6.0	8.0	10.0	12.0	1.0	1.0	9.0	11.0	16.0
Kingella oralis (SP393)	1.0	1.0	1.0	1.0	1.0	227.0	230.0	256.0	289.0	401.0
Actinomyces sp. HMT448 (SP394)	1.0	1.0	1.0	1.0	1.0	181.0	477.0	494.0	956.0	973.0
Leptotrichia sp. HMT225 (SP40)	1.0	1.0	1.0	1.0	1.0	327.0	453.0	481.0	504.0	634.0
Fusobacterium sp. HMT203 (SP42)	1.0	1.0	1.0	1.0	1.0	92.0	185.0	314.0	415.0	463.0
Neisseria elongata (SP45)	2714.0	4434.75	6155.5	7876.25	9597.0	464.0	634.0	694.0	741.0	847.0
Treponema maltophilum (SP46)	42.0	44.0	46.0	48.0	50.0	68.0	149.0	163.0	226.0	239.0
Selenomonas infelix (SP49)	111.0	114.25	117.5	120.75	124.0	236.0	257.0	273.0	320.0	344.0
Treponema sp. HMT237 (SP5)	1.0	1.0	1.0	1.0	1.0	35.0	61.0	79.0	88.0	227.0
Actinomyces dentalis (SP51)	1.0	1.0	1.0	1.0	1.0	801.0	850.0	1006.0	1281.0	1624.0
Fusobacterium nucleatum_subsp._vincentii (SP54)	179.0	235.0	291.0	347.0	403.0	198.0	398.0	497.0	539.0	752.0
Leptotrichia sp. HMT215 (SP57)	1.0	1.0	1.0	1.0	1.0	186.0	281.0	299.0	343.0	411.0
Streptococcus downii (SP58)	1529.0	1592.5	1656.0	1719.5	1783.0	790.0	1040.0	1127.0	1157.0	1253.0
Corynebacterium matruchotii (SP6)	1.0	1.0	1.0	1.0	1.0	2414.0	2452.0	2649.0	3855.0	4249.0
Treponema denticola (SP60)	14.0	15.25	16.5	17.75	19.0	178.0	182.0	193.0	212.0	710.0
Veillonella parvula (SP63)	758.0	871.75	985.5	1099.25	1213.0	589.0	885.0	951.0	1071.0	1191.0
Lautropia mirabilis (SP64)	174.0	179.75	185.5	191.25	197.0	730.0	857.0	872.0	1090.0	1351.0
Fusobacterium nucleatum (SP7)	46.0	73.75	101.5	129.25	157.0	1930.0	2431.0	2968.0	3624.0	4028.0
Lachnoanaerobaculum umeaense (SP70)	1.0	13.0	25.0	37.0	49.0	154.0	191.0	195.0	227.0	347.0
Capnocytophaga leadbetteri (SP71)	1.0	1.0	1.0	1.0	1.0	606.0	612.0	664.0	778.0	811.0
Haemophilus parainfluenzae (SP72)	1.0	4.75	8.5	12.25	16.0	552.0	700.0	743.0	867.0	968.0
Catonella morbi (SP76)	67.0	77.25	87.5	97.75	108.0	472.0	516.0	529.0	547.0	747.0
Leptotrichia buccalis (SP82)	1.0	2.5	4.0	5.5	7.0	1108.0	1222.0	1675.0	1762.0	1835.0
Leptotrichia shahii (SP86)	1.0	1.0	1.0	1.0	1.0	417.0	627.0	700.0	1075.0	2703.0
Fusobacterium sp. HMT204 (SP87)	1.0	1.0	1.0	1.0	1.0	33.0	40.0	59.0	83.0	100.0
Actinomyces sp. HMT897 (SP88)	1.0	1.0	1.0	1.0	1.0	309.0	418.0	532.0	571.0	899.0
Campylobacter showae (SP9)	849.0	926.0	1003.0	1080.0	1157.0	178.0	202.0	251.0	270.0	343.0
Prevotella intermedia (SP92)	2035.0	2126.25	2217.5	2308.75	2400.0	440.0	575.0	662.0	783.0	1001.0
Streptococcus sanguinis (SP95)	697.0	796.5	896.0	995.5	1095.0	1713.0	1802.0	1835.0	2238.0	2379.0
Granulicatella adiacens (SP96)	1154.0	1742.25	2330.5	2918.75	3507.0	869.0	1121.0	1135.0	1296.0	1525.0
Enterobacter cancerogenus (SP97)	1164.0	1992.25	2820.5	3648.75	4477.0	1.0	1.0	1.0	1.0	1.0
Treponema socranskii (SP98)	98.0	105.0	112.0	119.0	126.0	167.0	264.0	300.0	352.0	586.0
Lacrimispora xylanolytica_nov_88.613% (SPN105)	1.0	1.0	1.0	1.0	1.0	270.0	280.0	303.0	347.0	953.0
Porphyromonas sp. HMT284 nov_97.746% (SPN108)	1.0	1.0	1.0	1.0	1.0	163.0	203.0	254.0	347.0	394.0
Prevotella sp. HMT305 nov_93.456% (SPN122)	1.0	4.0	7.0	10.0	13.0	1.0	1.0	1.0	1.0	1.0
Actinomyces israelii_nov_96.838% (SPN134)	1.0	1.0	1.0	1.0	1.0	309.0	314.0	321.0	433.0	571.0
Streptococcus sanguinis_nov_97.782% (SPN153)	42.0	53.0	64.0	75.0	86.0	135.0	146.0	318.0	345.0	481.0
Bergeyella zoohelcum_nov_93.004% (SPN8)	11.0	106.0	201.0	296.0	391.0	4.0	7.0	7.0	7.0	12.0
Veillonella multispecies_spp11_2 (SPP11)	2451.0	2716.0	2981.0	3246.0	3511.0	2103.0	2321.0	2334.0	2797.0	2893.0
Serratia multispecies_spp15_2 (SPP15)	1678.0	1795.5	1913.0	2030.5	2148.0	1.0	1.0	1.0	1.0	1.0
Fusobacterium multispecies_spp21_2 (SPP21)	39.0	46.25	53.5	60.75	68.0	143.0	159.0	275.0	289.0	316.0
Fusobacterium multispecies_sppn10_3_nov_97.845% (SPPN10)	1.0	1.0	1.0	1.0	1.0	21.0	34.0	75.0	119.0	222.0