Percentile	0.0	25.0	50.0	75.0	100.0	0.0	25.0	50.0	75.0	100.0
Group	Baseline P2 +PMA	Baseline P2 +PMA	Baseline P2 +PMA	Baseline P2 +PMA	Baseline P2 +PMA	Saliva P2 +PMA	Saliva P2 +PMA	Saliva P2 +PMA	Saliva P2 +PMA	Saliva P2 +PMA
Streptococcus sp. HMT057 (SP103)	1.0	1.0	1.0	1.0	1.0	15.0	16.5	22.0	26.0	28.0
Eikenella corrodens (SP104)	93.0	149.0	206.5	338.0	477.0	21.0	25.0	25.5	31.25	41.0
Lautropia mirabilis (SP106)	5.0	10.25	17.5	33.75	68.0	124.0	169.75	186.5	213.0	400.0
Veillonella tobetsuensis (SP107)	76.0	126.25	138.0	179.25	205.0	237.0	250.0	262.5	272.0	277.0
Schaalia sp. HMT180 (SP109)	1.0	1.0	1.0	1.0	10.0	136.0	139.25	149.0	161.0	174.0
Aggregatibacter segnis (SP111)	247.0	436.75	493.0	534.5	769.0	10.0	17.5	22.0	27.25	30.0
Prevotella melaninogenica (SP120)	64.0	143.0	300.5	836.75	1170.0	6187.0	6849.25	7149.5	7190.25	7876.0
Oribacterium sinus (SP123)	1.0	1.0	1.0	1.0	1.0	161.0	172.25	198.5	224.75	293.0
Alloprevotella sp. HMT914 (SP126)	1.0	1.0	1.0	1.5	11.0	146.0	148.25	153.5	181.25	189.0
Fusobacterium hwasookii (SP127)	1.0	1.0	1.0	17.25	38.0	8.0	28.75	31.5	37.25	45.0
Fusobacterium periodonticum (SP130)	162.0	262.5	359.0	440.5	819.0	1639.0	1961.25	2132.5	2429.75	2520.0
Aggregatibacter sp. HMT458 (SP136)	15.0	21.75	47.0	136.0	444.0	21.0	24.25	26.5	30.25	36.0
Haemophilus parainfluenzae (SP14)	10286.0	15059.0	15814.5	19025.75	27948.0	3784.0	4224.75	4503.5	4594.0	5078.0
Prevotella jejuni (SP143)	1.0	1.0	1.0	7.0	12.0	387.0	421.5	467.5	506.75	745.0
Streptococcus gordonii (SP144)	1.0	1.0	3.5	11.0	31.0	16.0	22.0	27.0	29.0	43.0
Neisseria elongata (SP145)	35.0	64.25	739.5	2451.75	4165.0	53.0	56.5	61.0	70.0	73.0
Streptococcus infantis_clade_431 (SP148)	1.0	1.0	1.0	3.5	19.0	325.0	354.0	371.5	390.5	439.0
Porphyromonas catoniae (SP15)	21.0	56.25	82.0	153.0	262.0	40.0	45.25	46.5	50.75	52.0
Haemophilus haemolyticus (SP163)	1.0	7.75	12.0	21.25	33.0	84.0	84.75	94.0	104.75	109.0
Prevotella shahii (SP165)	1.0	1.0	3.5	10.0	21.0	179.0	209.75	225.5	230.75	250.0
Haemophilus pittmaniae (SP169)	1.0	1.0	25.5	51.0	176.0	1.0	1.0	7.5	15.5	20.0
Streptococcus australis (SP17)	1.0	1.0	1.0	1.0	1.0	149.0	179.25	226.5	252.75	263.0
Lancefieldella parvula (SP174)	1.0	1.0	1.0	1.0	1.0	103.0	129.0	137.5	152.75	157.0
Streptococcus sanguinis (SP179)	1.0	1.0	1.0	7.75	12.0	86.0	100.25	128.5	138.75	153.0
Alloprevotella sp. HMT473 (SP181)	8.0	13.75	16.0	19.0	47.0	138.0	152.25	164.0	170.5	200.0
Streptococcus chosunense (SP182)	1.0	1.0	1.0	1.0	1.0	104.0	126.75	144.5	146.5	153.0
Enterobacter cancerogenus (SP184)	1.0	1.0	1.0	1.0	5393.0	1.0	1.0	1.0	1.0	1.0
Leptotrichia sp. HMT417 (SP185)	1.0	1.0	1.0	1.0	1.0	636.0	702.5	795.5	867.5	1364.0
Haemophilus sp. HMT036 (SP188)	1.0	14.0	21.5	38.5	71.0	166.0	174.75	188.5	195.5	212.0
Schaalia odontolytica (SP19)	1.0	1.0	3.5	7.5	14.0	901.0	944.25	978.0	1134.0	1227.0
Enterobacter asburiae (SP199)	1.0	1.0	1.0	1.0	2607.0	1.0	1.0	1.0	1.0	1.0
Veillonella parvula (SP2)	850.0	1736.25	1959.0	2089.25	2686.0	399.0	454.5	506.5	536.0	566.0
Lachnoanaerobaculum gingivalis (SP20)	1.0	1.0	1.0	1.0	1.0	16.0	30.25	34.5	50.75	65.0
Neisseria subflava (SP200)	321.0	460.25	625.0	1011.75	1632.0	115.0	125.5	145.5	164.0	173.0
Rothia dentocariosa (SP201)	1.0	1.0	5.0	7.75	11.0	46.0	48.5	58.0	61.5	72.0
Prevotella vespertina (SP204)	1.0	1.0	1.0	1.0	22.0	297.0	315.0	334.0	375.5	446.0
Actinomyces sp. HMT175 (SP205)	1.0	1.0	1.0	1.0	1.0	1.0	3.25	15.0	25.25	39.0
Saccharibacteria_(TM7)_[G-6] bacterium HMT870 (SP207)	1.0	1.0	5.0	7.25	20.0	110.0	111.0	121.0	135.5	142.0
Cutibacterium acnes (SP222)	1.0	1.0	1.0	1.0	13.0	1.0	1.0	1.0	1.0	3.0
Streptococcus cristatus_clade_578 (SP24)	1.0	1.0	1.0	1.0	14.0	9.0	14.25	15.5	19.75	23.0
Streptococcus sp. HMT066 (SP246)	1.0	1.0	1.0	1.0	1.0	127.0	152.25	169.5	184.5	214.0
Streptococcus mitis (SP249)	1.0	1.0	1.0	1.0	1.0	419.0	543.0	587.0	602.5	606.0
Prevotella nanceiensis (SP25)	1.0	4.5	42.0	207.75	299.0	1448.0	1531.75	1607.5	1640.5	1753.0
Aggregatibacter sp. HMT513 (SP252)	35.0	101.5	139.0	169.25	318.0	1.0	6.0	23.0	25.75	32.0
Campylobacter showae (SP265)	1.0	1.0	36.5	172.25	221.0	25.0	27.75	35.0	37.75	66.0
Streptococcus oralis_subsp._dentisani_clade_058 (SP269)	1.0	1.0	1.0	5.0	28.0	17.0	27.0	35.0	37.0	47.0
Lachnospiraceae_[G-2] bacterium HMT096 (SP27)	1.0	1.0	1.0	1.0	1.0	258.0	328.5	467.0	640.0	956.0
Gemella sanguinis (SP285)	1.0	3.25	9.0	15.0	23.0	50.0	59.25	72.0	82.5	92.0
Novosphingobium clariflavum (SP287)	1.0	1.0	1.0	4.0	8.0	1.0	1.0	1.0	1.0	1.0
Prevotella aurantiaca (SP288)	1.0	1.0	1.0	1.0	5.0	220.0	231.5	235.5	247.0	253.0
Streptococcus oralis_subsp._tigurinus_clade_071 (SP29)	1.0	9.75	16.5	23.75	31.0	1.0	1.0	1.0	1.0	14.0
Veillonella dispar (SP3)	433.0	554.5	637.0	1046.75	1607.0	699.0	877.0	892.5	903.5	913.0
Alloprevotella tannerae (SP315)	1.0	1.0	1.0	10.0	38.0	169.0	180.75	199.0	205.25	236.0
Klebsiella aerogenes (SP327)	1.0	1.0	1.0	1.0	1268.0	1.0	1.0	1.0	1.0	1.0
Enterobacter mori (SP330)	1.0	1.0	1.0	1.0	1168.0	1.0	1.0	1.0	1.0	1.0
Porphyromonas pasteri (SP34)	412.0	856.0	1038.0	1716.5	2299.0	3980.0	4241.5	4578.5	4695.0	4915.0
Fusobacterium sp. HMT204 (SP343)	1.0	1.0	1.0	6.75	18.0	1.0	8.25	9.5	13.0	18.0
Neisseria mucosa (SP346)	1.0	141.75	571.5	1355.0	2044.0	153.0	162.75	167.5	177.5	221.0
Veillonella atypica (SP35)	262.0	337.75	1304.0	2549.25	3265.0	967.0	1045.5	1109.0	1163.5	1220.0
Streptococcus sp. HMT061 (SP366)	1.0	1.0	1.0	2.25	7.0	68.0	80.25	82.0	90.5	118.0
Agrobacterium tumefaciens (SP369)	1.0	1.0	1.0	1.0	5.0	1.0	1.0	1.0	1.0	1.0
Haemophilus sputorum (SP371)	1.0	1.0	80.0	340.75	390.0	162.0	207.0	231.0	242.25	260.0
Rothia mucilaginosa (SP391)	1.0	8.25	14.0	29.5	102.0	295.0	360.0	392.0	421.0	537.0
Streptococcus sp. HMT423 (SP4)	1.0	7.0	38.5	91.0	251.0	161.0	260.5	279.0	298.25	311.0
Leptotrichia sp. HMT215 (SP40)	1.0	1.0	1.0	1.0	4.0	195.0	218.5	235.0	268.75	357.0
Gemella haemolysans (SP41)	1.0	1.0	1.0	1.0	9.0	22.0	29.25	36.0	42.75	51.0
Actinomyces graevenitzii (SP42)	1.0	1.0	1.0	1.0	1.0	81.0	97.0	114.0	119.0	142.0
Phyllobacterium myrsinacearum (SP44)	1.0	1.0	1.0	1.0	4.0	1.0	1.0	1.0	1.0	1.0
Streptococcus sp. HMT064 (SP443)	1.0	1.0	1.0	1.75	9.0	1.0	35.0	41.0	44.75	48.0
Campylobacter concisus (SP45)	100.0	224.0	957.5	3403.5	4310.0	756.0	858.0	875.5	899.0	945.0
Granulicatella adiacens (SP46)	12.0	18.25	30.0	66.0	124.0	347.0	357.5	368.0	408.5	444.0
Prevotella salivae (SP47)	1.0	1.0	7.0	39.75	60.0	343.0	381.0	430.0	472.25	495.0
Schaalia lingnae (SP49)	1.0	1.0	1.0	1.0	5.0	99.0	113.75	122.5	129.75	135.0
Stomatobaculum sp. HMT097 (SP5)	1.0	1.0	1.0	1.0	1.0	36.0	43.25	54.0	66.25	80.0
Riemerella sp. HMT322 (SP51)	1.0	1.0	1.0	4.25	13.0	133.0	146.0	153.0	162.25	169.0
Alloprevotella sp. HMT308 (SP52)	1.0	1.0	1.0	2.5	13.0	499.0	550.75	589.5	664.25	761.0
Neisseria flava (SP53)	5948.0	7168.0	9158.5	10765.25	19952.0	290.0	307.75	351.0	362.0	366.0
Absconditabacteria_(SR1)_[G-1] bacterium HMT875 (SP553)	1.0	1.0	1.0	14.0	22.0	106.0	107.25	120.0	137.25	140.0
Fusobacterium nucleatum (SP56)	1.0	15.25	25.5	37.25	112.0	77.0	91.75	107.0	114.75	119.0
Schaalia sp. HMT172 (SP57)	1.0	1.0	1.0	1.0	1.0	111.0	121.75	153.0	170.75	174.0
Catonella morbi (SP58)	1.0	1.0	1.0	1.0	1.0	138.0	155.0	167.0	184.25	203.0
Capnocytophaga sputigena (SP59)	1.0	1.0	5.0	16.75	23.0	58.0	65.75	69.0	77.5	88.0
Neisseria sicca (SP614)	1.0	97.75	156.0	249.25	1177.0	1.0	1.0	1.0	1.0	1.0
Acinetobacter johnsonii (SP62)	1.0	1.0	1.0	4.25	8.0	1.0	1.0	1.0	1.0	1.0
Klebsiella pneumoniae (SP63)	1.0	18.5	75.5	337.75	728.0	1.0	1.0	1.0	2.5	4.0
Neisseria flavescens (SP68)	586.0	791.75	1613.5	3840.25	5216.0	1197.0	1268.25	1438.5	1485.0	1561.0
Raoultella planticola (SP69)	1.0	1.0	1.0	1.0	1262.0	1.0	1.0	1.0	1.0	1.0
Streptococcus downii (SP70)	1.0	1.0	1.0	1.0	4.0	182.0	208.0	216.0	227.75	248.0
Saccharibacteria_(TM7)_[G-1] bacterium HMT352 (SP75)	1.0	6.5	24.0	79.25	127.0	253.0	264.5	297.5	308.75	347.0
Prevotella pallens (SP76)	1.0	1.0	7.0	14.75	23.0	1094.0	1162.25	1270.0	1371.0	1395.0
Prevotella histicola (SP79)	1.0	1.0	1.0	11.75	26.0	354.0	524.5	534.0	542.75	757.0
Gemella morbillorum (SP8)	1.0	1.0	1.0	1.0	12.0	1.0	1.0	1.0	1.0	1.0
Streptococcus oralis (SP80)	1.0	9.75	53.5	145.5	179.0	29.0	31.5	38.5	41.75	84.0
Streptococcus oralis_subsp._tigurinus_clade_070 (SP82)	1.0	1.0	4.5	16.5	32.0	3.0	5.5	7.5	9.5	11.0
Aggregatibacter aphrophilus (SP84)	1.0	29.5	46.0	76.25	159.0	29.0	31.25	46.5	63.25	71.0
Streptococcus parasanguinis_clade_411 (SP88)	1.0	1.0	1.0	1.0	1.0	217.0	253.5	296.5	314.0	326.0
Streptococcus salivarius (SP89)	1.0	3.25	53.5	179.75	305.0	1572.0	1606.0	1640.5	1780.75	2140.0
Solobacterium moorei (SP9)	1.0	1.0	1.0	1.0	14.0	70.0	79.5	88.5	96.0	104.0
Veillonella rogosae (SP90)	1862.0	2849.0	3588.5	7116.75	10720.0	2998.0	3464.0	3552.0	3649.75	4003.0
Neisseria perflava (SP94)	767.0	952.75	2414.0	6377.25	9141.0	2974.0	3300.0	3654.5	3758.5	3919.0
Actinomyces sp. HMT169 (SP95)	1.0	1.0	1.0	1.0	1.0	54.0	93.25	101.5	112.0	119.0
Granulicatella elegans (SP99)	1.0	1.0	1.0	1.0	1.0	1.0	11.75	18.0	23.5	30.0
Enterobacter mori_nov_97.951% (SPN106)	1.0	1.0	1.0	1.0	1172.0	1.0	1.0	1.0	1.0	1.0
Prevotella sp. HMT305 nov_93.865% (SPN148)	1.0	1.0	1.0	1.0	8.0	189.0	193.75	207.5	232.5	243.0
Campylobacter concisus_nov_96.963% (SPN15)	6.0	20.25	274.0	945.5	1159.0	13.0	15.25	16.0	16.75	21.0
Neisseria sp. HMT020 nov_94.070% (SPN248)	10.0	15.75	84.5	286.25	699.0	7.0	8.0	9.5	11.75	16.0
Leptotrichia sp. HMT215 nov_96.963% (SPN370)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	22.0
Haemophilus haemolyticus_nov_97.947% (SPN447)	1.0	1.0	1.0	1.5	6.0	5.0	7.5	9.5	14.5	17.0
Alloprevotella sp. HMT473 nov_97.347% (SPN70)	1.0	1.0	1.0	1.0	10.0	463.0	490.0	518.5	567.25	578.0
Oribacterium multispecies_spp10_2 (SPP10)	1.0	1.0	1.0	1.0	1.0	92.0	108.25	127.0	143.5	167.0
Veillonella multispecies_spp25_2 (SPP25)	2998.0	5337.0	8157.0	10897.25	14450.0	478.0	502.75	559.0	575.5	603.0
Streptococcus multispecies_spp29_2 (SPP29)	1.0	1.0	1.0	1.0	10.0	546.0	556.75	572.0	586.5	708.0
Mycolicibacterium multispecies_spp31_2 (SPP31)	1.0	1.0	1.0	1.0	5.0	1.0	1.0	1.0	1.0	1.0
Streptococcus multispecies_spp53_2 (SPP53)	1.0	1.0	1.0	5.5	11.0	70.0	91.0	96.5	99.75	110.0
Veillonella multispecies_spp6_3 (SPP6)	390.0	486.0	595.5	929.75	1607.0	531.0	600.5	654.0	669.25	715.0
Streptococcus multispecies_sppn11_2_nov_97.976% (SPPN11)	1.0	1.0	1.0	1.0	4.0	41.0	41.75	44.5	50.25	53.0