Taxon	A.1	A.2	A.3	A.4	A.5	Y.1	Y.2	Y.3	Y.4	Y.5	CS.1	CS.2	CS.3	CS.4	CS.5

GLYCOGENSYNTH-PWY: glycogen biosynthesis I (from ADP-D-Glucose)	100.307	169.754	211.721	323.372	1e-09	63.509	47.194	564.557	49.4432	16.2282	256.972	733.344	483.539	644.31	77.6747
PWY0-1296: purine ribonucleosides degradation	12.4382	35.0352	25.2567	108.372	1e-09	154.896	84.3184	536.23	39.6907	5.69817	299.212	785.397	189.531	268.515	42.4975
PWY-1042: glycolysis IV	36.8693	71.5113	239.936	121.555	1e-09	75.9544	0	0	0	0	148.564	619.102	677.785	168.895	0
PWY-6122: 5-aminoimidazole ribonucleotide biosynthesis II	40.2298	54.27	256.636	158.68	1e-09	228.678	62.4617	348.421	85.7063	16.2584	64.9097	462.979	208.905	106.35	22.1235
PWY-6277: superpathway of 5-aminoimidazole ribonucleotide biosynthesis	40.2298	54.27	256.636	158.68	1e-09	228.678	62.4617	348.421	85.7063	16.2584	64.9097	462.979	208.905	106.35	22.1235
PWY-5100: pyruvate fermentation to acetate and lactate II	0	0	0	0	1e-09	0	0	109.767	51.8475	0	485.892	711.338	156.134	544.343	0
PWY-6121: 5-aminoimidazole ribonucleotide biosynthesis I	40.3539	54.2054	233.525	151.987	1e-09	225.792	63.9379	349.827	83.1789	15.839	59.0017	440.482	210.386	97.034	22.317
PWY-6527: stachyose degradation	0	0	74.8947	90.3529	1e-09	376.625	273.629	350.509	91.7781	0	73.2464	408.182	109.982	124.219	21.5661
PWY-7238: sucrose biosynthesis II	116.08	191.8	328.907	308.99	1e-09	16.2176	0	141.966	70.0236	9.15687	0	214.201	299.527	25.4924	26.5466
PWY-6609: adenine and adenosine salvage III	23.2846	51.1908	60.0518	159.633	1e-09	93.6387	50.2053	310.332	52.3388	8.78056	56.1117	413.409	202.394	93.8134	28.8762
DTDPRHAMSYN-PWY: dTDP-β-L-rhamnose biosynthesis	21.2259	51.3349	218.85	121.882	1e-09	98.0781	64.3191	246.073	30.6726	14.1357	65.7324	328.074	204.727	90.5927	40.7379
PWY-7221: guanosine ribonucleotides de novo biosynthesis	8.69747	40.9078	206.533	121.649	1e-09	65.9102	37.0802	258.134	65.9308	6.1138	65.7566	278.511	198.368	114.379	25.7448
PWY-6123: inosine-5'-phosphate biosynthesis I	0	0	89.1045	58.8479	1e-09	196.648	66.7443	372.273	76.1143	0	73.6285	369.216	77.1186	68.6978	0
PWY-7234: inosine-5'-phosphate biosynthesis III	0	0	89.1045	39.496	1e-09	195.744	66.7247	372.273	72.281	0	73.6285	369.216	77.1186	68.6978	0
PWY-6151: S-adenosyl-L-methionine salvage I	31.0237	66.7094	138.003	65.1392	1e-09	59.3694	39.2061	196.777	28.6606	10.2602	68.0953	327.441	195.339	172.538	0
VALSYN-PWY: L-valine biosynthesis	29.3978	47.3472	141.369	162.914	1e-09	22.5393	0	135.384	62.1823	9.89959	102.513	280.352	192.251	122.362	15.3433
P41-PWY: pyruvate fermentation to acetate and (S)-lactate I	0	0	0	0	1e-09	0	0	109.767	51.8475	0	364.626	417.162	96.5896	262.968	0
PWY-6124: inosine-5'-phosphate biosynthesis II	0	0	63.0477	52.3554	1e-09	174.325	54.8036	334.342	83.0991	0	63.5364	322.329	58.9161	55.3389	0
PWY-5686: UMP biosynthesis I	16.1769	34.9138	199.891	89.2653	1e-09	74.8326	48.879	183.918	70.4733	7.17909	47.1942	277.234	122.371	80.4988	0
PWY-7791: UMP biosynthesis III	16.1769	34.9138	199.891	89.2653	1e-09	74.8326	48.879	183.918	70.4733	7.17909	35.3334	277.234	122.371	66.0081	0
PWY-7790: UMP biosynthesis II	16.1769	34.9138	199.891	89.2653	1e-09	74.8326	48.879	183.918	70.4733	7.17909	35.3334	277.234	122.371	66.0081	0
LACTOSECAT-PWY: lactose and galactose degradation I	0	0	0	36.3069	1e-09	0	0	67.972	9.35405	0	330.633	187.77	96.8113	466.888	0
ILEUSYN-PWY: L-isoleucine biosynthesis I (from threonine)	0	0	103.698	113.399	1e-09	8.41475	0	64.5349	29.0602	0	73.3774	230.636	155.591	99.6971	0
PWY-6386: UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)	0	33.6243	96.696	73.1501	1e-09	41.3084	27.167	144.04	22.5278	0	31.9207	157.548	126.065	55.3464	12.4419
PWY-6387: UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)	11.9779	34.6028	106.767	77.1865	1e-09	38.6966	24.0928	129.952	20.3326	0	28.0376	148.887	123.235	60.2034	13.3514
OANTIGEN-PWY: O-antigen building blocks biosynthesis (E. coli)	0	0	82.4235	15.4095	1e-09	64.6141	43.2369	150.75	26.3135	0	56.6791	216.878	78.0463	69.3966	0
GLYCOLYSIS: glycolysis I (from glucose 6-phosphate)	0	0	0	6.45115	1e-09	0	0	0	0	0	135.644	367.846	79.7938	199.945	0
PWY-3841: folate transformations II (plants)	0	16.8756	74.8232	95.7989	1e-09	28.1616	19.0033	135.388	24.9363	0	29.301	144.073	118.208	84.3813	16.9882
BRANCHED-CHAIN-AA-SYN-PWY: superpathway of branched chain amino acid biosynthesis	0	0	81.7659	94.8744	1e-09	7.64679	0	61.1218	26.3319	0	75.2025	220.155	123.12	94.0651	0
PWY-2942: L-lysine biosynthesis III	0	0	34.3291	84.1349	1e-09	32.2835	26.223	212.496	29.3613	0	45.4054	144.657	105.76	67.2942	0
UDPNAGSYN-PWY: UDP-N-acetyl-D-glucosamine biosynthesis I	0	0	67.6819	11.9093	1e-09	59.6608	38.8293	162.296	35.5354	0	57.9367	207.83	65.3933	68.0846	0
PWY-6317: D-galactose degradation I (Leloir pathway)	0	0	30.6165	102.006	1e-09	0	0	219.396	102.505	0	15.2338	106.126	77.4353	59.8176	35.716
PWY-7229: superpathway of adenosine nucleotides de novo biosynthesis I	0	0	0	0	1e-09	0	0	99.6912	0	0	107.54	332.985	86.155	113.971	0
PEPTIDOGLYCANSYN-PWY: peptidoglycan biosynthesis I (meso-diaminopimelate containing)	9.90208	26.3972	91.5714	68.9325	1e-09	35.2236	20.7376	115.009	19.998	0	27.0293	136.055	107.021	56.7965	13.3043
TRNA-CHARGING-PWY: tRNA charging	0	0	88.0018	86.6317	1e-09	32.1603	0	135.028	32.5178	0	21.4188	160.191	103.127	59.8183	0
PWY-5103: L-isoleucine biosynthesis III	0	0	84.3321	93.3108	1e-09	5.92496	0	47.8712	21.9486	0	58.4744	192.5	131.757	82.5158	0
PWY-5484: glycolysis II (from fructose 6-phosphate)	0	0	0	6.40704	1e-09	0	0	0	0	0	89.5741	310.345	78.3225	155.424	0
COA-PWY: coenzyme A biosynthesis I (prokaryotic)	11.1035	28.6901	47.5419	86.4734	1e-09	17.824	7.34404	83.0195	22.6151	7.61523	27.2733	99.4784	89.0928	68.5137	31.7041
PWY-7953: UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)	11.0095	30.999	93.9321	75.6498	1e-09	15.7112	0	4.5298	0	0	25.9918	155.077	112.772	79.8926	12.7299
PWY-6126: superpathway of adenosine nucleotides de novo biosynthesis II	0	0	0	0	1e-09	0	0	68.4069	0	0	96.0679	279.504	64.9984	102.56	0
COA-PWY-1: superpathway of coenzyme A biosynthesis III (mammals)	11.2849	30.0101	53.3724	85.7485	1e-09	15.8195	8.47425	92.3041	24.3748	0	27.3402	106.684	79.4874	60.679	14.6094
PWY-7228: superpathway of guanosine nucleotides de novo biosynthesis I	0	0	0	0	1e-09	0	0	59.2507	0	0	72.0794	273.963	93.4259	109.563	0
PWY-841: superpathway of purine nucleotides de novo biosynthesis I	0	0	0	0	1e-09	0	0	91.7399	0	0	67.3438	288.297	75.5967	81.3312	0
PWY-5097: L-lysine biosynthesis VI	0	0	35.7166	64.2908	1e-09	25.7739	19.4742	142.594	23.8289	0	24.7565	111.174	89.6519	61.9814	0
PWY-7851: coenzyme A biosynthesis II (eukaryotic)	11.1035	28.6901	47.5419	84.2581	1e-09	14.1061	7.34404	83.0195	22.4104	0	26.0326	99.4784	73.5426	59.3903	15.6256
PWY-2941: L-lysine biosynthesis II	0	0	17.7067	10.2842	1e-09	29.8202	23.0793	182.102	23.8656	0	33.4051	110.284	62.8176	57.6917	0
PWY-7208: superpathway of pyrimidine nucleobases salvage	0	0	0	0	1e-09	0	0	42.5617	0	0	65.8153	272.405	81.9641	82.2352	0
PWY66-429: fatty acid biosynthesis initiation (mitochondria)	5.85217	12.3613	44.2842	15.7396	1e-09	8.37215	0	8.18815	0	6.23178	86.2294	215.686	72.495	69.1273	0
PWY-5973: cis-vaccenate biosynthesis	0	0	18.1115	68.0889	1e-09	0	0	0	0	0	109.859	199.515	48.2673	100.111	0
PWY-6385: peptidoglycan biosynthesis III (mycobacteria)	0	26.3972	91.5714	68.9325	1e-09	17.9945	0	6.32545	0	0	27.4759	131.915	98.2641	48.7104	11.8985
ARGSYNBSUB-PWY: L-arginine biosynthesis II (acetyl cycle)	11.1764	16.9447	70.386	62.2502	1e-09	4.34736	0	26.1466	19.5881	4.42557	32.5042	108.043	96.6985	55.9213	16.0253
PWY-7663: gondoate biosynthesis (anaerobic)	0	0	14.8386	63.8473	1e-09	0	0	0	0	0	102.741	183.576	42.6509	92.5672	0
ARGSYN-PWY: L-arginine biosynthesis I (via L-ornithine)	10.8176	14.725	62.9909	65.2504	1e-09	5.80399	0	32.4678	17.7748	0	17.2324	93.5059	108.655	49.0179	14.4424
PWY-6125: superpathway of guanosine nucleotides de novo biosynthesis II	0	0	0	0	1e-09	0	0	48.8119	0	0	63.0728	221.31	56.545	95.8626	0
PWY-6700: queuosine biosynthesis I (de novo)	4.42285	11.7091	69.5038	54.7245	1e-09	17.0332	13.2821	65.7793	7.06307	0	12.5337	76.0408	47.741	31.0052	11.9509
PWY0-162: superpathway of pyrimidine ribonucleotides de novo biosynthesis	0	0	0	0	1e-09	0	0	0	0	0	42.549	247.199	57.0475	69.5458	0
NONMEVIPP-PWY: methylerythritol phosphate pathway I	17.1009	37.5717	54.7004	63.4889	1e-09	5.5031	0	16.813	7.95507	7.03361	5.89329	49.6107	94.7465	28.8562	14.8069
PWY-7220: adenosine deoxyribonucleotides de novo biosynthesis II	0	0	0	0	1e-09	0	0	32.9873	0	0	75.9821	177.672	32.3838	83.0735	0
PWY-7222: guanosine deoxyribonucleotides de novo biosynthesis II	0	0	0	0	1e-09	0	0	32.9873	0	0	75.9821	177.672	32.3838	83.0735	0
ANAGLYCOLYSIS-PWY: glycolysis III (from glucose)	0	0	0	0	1e-09	0	0	0	0	0	57.5594	210.397	22.0839	86.4437	0
SER-GLYSYN-PWY: superpathway of L-serine and glycine biosynthesis I	0	0	0	73.1012	1e-09	0	0	0	0	0	45.663	86.8129	22.3963	69.0732	0
GLUTORN-PWY: L-ornithine biosynthesis I	9.0797	17.5273	54.9738	43.6748	1e-09	2.47146	0	14.7898	6.21441	3.17279	5.37877	48.5835	44.3088	25.0736	17.2119
PWY-7111: pyruvate fermentation to isobutanol (engineered)	0	0	0	0	1e-09	0	0	0	0	0	50.3111	118.036	33.2222	63.1861	0
PWY-I9: L-cysteine biosynthesis VI (from L-methionine)	0	0	0	0	1e-09	0	0	0	0	0	58.8673	130.446	18.5868	55.7202	0
PWY-7197: pyrimidine deoxyribonucleotide phosphorylation	0	0	0	0	1e-09	0	0	27.6976	0	0	34.1332	104.861	31.5262	61.6344	0
PWY0-1319: CDP-diacylglycerol biosynthesis II	4.39968	10.5735	54.1381	38.0784	1e-09	2.79486	0	0	0	0	10.1436	51.5097	51.4408	27.2814	8.45785
PWY-5667: CDP-diacylglycerol biosynthesis I	4.39968	10.5735	54.1381	38.0784	1e-09	2.79486	0	0	0	0	10.1436	51.5097	51.4408	27.2814	8.45785
CALVIN-PWY: Calvin-Benson-Bassham cycle	0	0	0	0	1e-09	0	0	0	0	0	60.7646	110.009	20.9672	61.9982	0
PANTOSYN-PWY: superpathway of coenzyme A biosynthesis I (bacteria)	8.30518	20.9939	33.9777	31.5181	1e-09	7.97567	0	10.5924	0	0	15.2852	46.8888	56.8132	20.4681	0
ASPASN-PWY: superpathway of L-aspartate and L-asparagine biosynthesis	0	0	0	1.80017	1e-09	0	0	0	0	0	49.3519	109.171	46.9319	43.7888	0
ANAEROFRUCAT-PWY: homolactic fermentation	0	0	0	0	1e-09	0	0	0	0	0	36.1199	131.638	14.0029	57.8076	0
GLUCONEO-PWY: gluconeogenesis I	0	0	0	0	1e-09	0	0	0	0	0	36.3959	132.149	14.7454	53.3824	0
PWY-6163: chorismate biosynthesis from 3-dehydroquinate	5.72846	19.3273	35.1633	39.2689	1e-09	0	0	3.68283	0	0	15.5743	44.0843	39.4146	24.3807	9.34164
PWY-724: superpathway of L-lysine, L-threonine and L-methionine biosynthesis II	0	0	23.3558	17.9387	1e-09	0	0	0	0	0	20.8266	68.9616	63.4591	39.7936	0
ARO-PWY: chorismate biosynthesis I	5.33847	15.2588	38.7218	32.6466	1e-09	0	0	4.47027	0	0	16.7866	47.4632	37.076	25.8865	9.39046