Percentile	0.0	25.0	50.0	75.0	100.0	0.0	25.0	50.0	75.0	100.0
Group	Healthy-Control	Healthy-Control	Healthy-Control	Healthy-Control	Healthy-Control	Healthy-Dfx_0.2mM	Healthy-Dfx_0.2mM	Healthy-Dfx_0.2mM	Healthy-Dfx_0.2mM	Healthy-Dfx_0.2mM
Prevotella melaninogenica (SP10)	52.0	60.0	68.0	89.5	111.0	1.0	2.0	3.0	39.0	75.0
Selenomonas sp. HMT138 (SP101)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.5	2.0
Fusobacterium periodonticum (SP104)	2.0	2.0	2.0	2.5	3.0	1.0	1.0	1.0	1.5	2.0
Abiotrophia defectiva (SP107)	6.0	12.5	19.0	21.0	23.0	1.0	1.0	1.0	1.0	1.0
Prevotella sp. HMT317 (SP108)	2.0	2.5	3.0	15.5	28.0	1.0	1.0	1.0	1.0	1.0
Capnocytophaga sp. HMT864 (SP109)	5.0	9.0	13.0	14.0	15.0	1.0	1.0	1.0	1.0	1.0
Selenomonas flueggei (SP112)	1.0	1.0	1.0	2.0	3.0	1.0	2.5	4.0	6.0	8.0
Porphyromonas catoniae (SP113)	29.0	30.0	31.0	44.0	57.0	1.0	1.0	1.0	1.0	1.0
Haemophilus parainfluenzae (SP12)	2.0	18.5	35.0	54.5	74.0	257.0	324.0	391.0	393.5	396.0
Oribacterium sp. HMT078 (SP122)	1.0	1.0	1.0	2.0	3.0	1.0	1.0	1.0	1.5	2.0
Streptococcus pneumoniae (SP124)	14.0	15.0	16.0	18.0	20.0	2.0	2.0	2.0	2.0	2.0
Selenomonas sp._Oral_Taxon_H23 (SP126)	8.0	12.5	17.0	20.5	24.0	2.0	2.0	2.0	2.5	3.0
Dialister invisus (SP13)	1.0	1.5	2.0	2.0	2.0	1.0	1.0	1.0	1.0	1.0
Selenomonas sp._Oral_Taxon_F85 (SP130)	1.0	1.5	2.0	2.5	3.0	5.0	11.0	17.0	19.5	22.0
Streptococcus sp. HMT056 (SP131)	1.0	2.0	3.0	30.0	57.0	1.0	1.0	1.0	1.0	1.0
Selenomonas sp._Oral_Taxon_G51 (SP133)	1.0	1.0	1.0	1.0	1.0	1.0	1.5	2.0	3.5	5.0
Streptococcus sp._Oral_Taxon_B66 (SP139)	4.0	5.0	6.0	6.5	7.0	1.0	1.5	2.0	2.5	3.0
Prevotella buccae (SP140)	4.0	4.5	5.0	5.0	5.0	1.0	1.0	1.0	1.5	2.0
Streptococcus oralis_subsp._tigurinus_clade_070 (SP145)	1.0	1.5	2.0	2.5	3.0	1.0	1.0	1.0	1.0	1.0
Veillonella sp._Oral_Taxon_G61 (SP147)	6.0	6.5	7.0	9.0	11.0	26.0	27.5	29.0	47.5	66.0
Selenomonas sp._Oral_Taxon_E20 (SP149)	4.0	5.0	6.0	12.0	18.0	2.0	3.0	4.0	4.0	4.0
Prevotella pallens (SP15)	2068.0	2174.0	2280.0	2381.5	2483.0	1.0	1.0	1.0	1.0	1.0
Selenomonas sputigena (SP151)	2.0	3.5	5.0	6.0	7.0	2.0	2.5	3.0	5.5	8.0
Capnocytophaga sputigena (SP155)	6.0	7.5	9.0	15.5	22.0	1.0	1.0	1.0	1.0	1.0
Campylobacter showae (SP156)	6.0	13.5	21.0	30.0	39.0	14.0	14.5	15.0	21.5	28.0
Prevotella saccharolytica (SP167)	1.0	1.0	1.0	6.5	12.0	1.0	1.0	1.0	1.0	1.0
Bergeyella sp. HMT900 (SP168)	2.0	2.5	3.0	3.5	4.0	1.0	1.0	1.0	1.0	1.0
Porphyromonas gingivalis (SP17)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.5	2.0
Streptococcus pseudopneumoniae (SP170)	1.0	2.0	3.0	6.0	9.0	1.0	1.0	1.0	1.5	2.0
Streptococcus sp._str._2136FAA (SP172)	1.0	1.5	2.0	2.0	2.0	1.0	1.0	1.0	1.0	1.0
Selenomonas sp. HMT134 (SP174)	1.0	1.0	1.0	1.0	1.0	1.0	1.5	2.0	2.0	2.0
Bacteroidales_[G-2] sp._Oral_Taxon_274 (SP176)	4.0	5.5	7.0	36.0	65.0	1.0	1.0	1.0	1.0	1.0
Selenomonas artemidis (SP177)	3.0	3.5	4.0	6.5	9.0	1.0	1.5	2.0	2.0	2.0
Streptococcus intermedius (SP178)	3.0	4.0	5.0	6.5	8.0	1.0	1.0	1.0	1.5	2.0
Veillonella dispar (SP18)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.5	2.0
Veillonella parvula (SP19)	5.0	7.0	9.0	9.5	10.0	39.0	41.5	44.0	48.5	53.0
Bergeyella sp. HMT322 (SP204)	2.0	2.0	2.0	3.0	4.0	1.0	1.0	1.0	1.0	1.0
Porphyromonas pasteri (SP22)	48.0	73.0	98.0	103.5	109.0	1.0	1.0	1.0	1.0	1.0
Streptococcus mitis (SP25)	72.0	111.0	150.0	385.0	620.0	8.0	35.5	63.0	109.5	156.0
Streptococcus gordonii (SP26)	37.0	45.0	53.0	66.5	80.0	53.0	56.5	60.0	133.5	207.0
Streptococcus sp. HMT064 (SP27)	12.0	17.0	22.0	28.5	35.0	1.0	3.5	6.0	7.5	9.0
Solobacterium moorei (SP28)	4.0	4.0	4.0	9.0	14.0	2.0	2.5	3.0	3.0	3.0
Streptococcus oralis_subsp._dentisani_clade_058 (SP29)	1.0	1.0	1.0	3.5	6.0	4.0	7.5	11.0	14.0	17.0
Streptococcus cristatus_clade_578 (SP3)	126.0	141.5	157.0	158.5	160.0	1469.0	2204.5	2940.0	3077.5	3215.0
Selenomonas sp. HMT146 (SP30)	56.0	95.0	134.0	152.0	170.0	10.0	19.0	28.0	34.0	40.0
Alloprevotella sp. HMT473 (SP31)	1.0	1.0	1.0	1.5	2.0	1.0	1.0	1.0	1.5	2.0
Streptococcus oralis_subsp._tigurinus_clade_071 (SP32)	129.0	153.0	177.0	272.5	368.0	42.0	43.0	44.0	48.0	52.0
Fusobacterium sp. HMT204 (SP33)	11.0	237.5	464.0	530.0	596.0	1.0	1.5	2.0	2.0	2.0
Streptococcus sp._str._C300 (SP35)	127.0	183.0	239.0	286.5	334.0	30.0	38.0	46.0	56.5	67.0
Porphyromonas sp. HMT278 (SP36)	30.0	44.0	58.0	60.5	63.0	1.0	1.0	1.0	1.0	1.0
Anaeroglobus geminatus (SP38)	1.0	1.0	1.0	4.5	8.0	1.0	2.0	3.0	3.0	3.0
Catonella morbi (SP39)	1.0	1.0	1.0	1.5	2.0	1.0	1.0	1.0	1.0	1.0
Campylobacter concisus (SP4)	94.0	101.0	108.0	120.5	133.0	2976.0	3309.0	3642.0	4504.5	5367.0
Fusobacterium nucleatum_subsp._vincentii (SP40)	2.0	5.5	9.0	9.5	10.0	1.0	1.0	1.0	1.0	1.0
Prevotella oralis (SP42)	1.0	4.5	8.0	10.5	13.0	1.0	61.0	121.0	125.5	130.0
Selenomonas sp._Oral_Taxon_F29 (SP43)	23.0	31.0	39.0	48.5	58.0	3.0	7.0	11.0	12.5	14.0
Campylobacter curvus (SP44)	2.0	3.0	4.0	5.0	6.0	90.0	157.5	225.0	292.0	359.0
Bacteroidales_[G-2] bacterium HMT274 (SP45)	6.0	11.5	17.0	28.0	39.0	1.0	1.0	1.0	1.0	1.0
Selenomonas sp._Oral_Taxon_H64 (SP46)	6.0	7.0	8.0	8.5	9.0	7.0	9.0	11.0	13.0	15.0
Streptococcus sanguinis (SP47)	142.0	151.0	160.0	178.0	196.0	24.0	26.0	28.0	34.5	41.0
Alloprevotella tannerae (SP48)	1.0	1.5	2.0	29.5	57.0	1.0	1.0	1.0	1.5	2.0
Selenomonas dianae (SP5)	49.0	55.5	62.0	69.5	77.0	50.0	68.5	87.0	95.5	104.0
Selenomonas sp. HMT481 (SP50)	30.0	33.0	36.0	36.0	36.0	29.0	38.5	48.0	49.0	50.0
Capnocytophaga gingivalis (SP53)	16.0	20.0	24.0	31.5	39.0	1.0	1.0	1.0	1.0	1.0
Prevotella denticola (SP54)	1.0	3.0	5.0	14.5	24.0	1.0	1.0	1.0	1.0	1.0
Streptococcus chosunense (SP56)	186.0	199.0	212.0	253.5	295.0	14.0	46.5	79.0	95.5	112.0
Centipeda sp._Oral_Taxon_D18 (SP57)	1.0	1.5	2.0	6.0	10.0	1.0	3.0	5.0	7.0	9.0
Prevotella oulorum (SP60)	2.0	3.0	4.0	5.0	6.0	1.0	1.0	1.0	1.0	1.0
Eikenella corrodens (SP62)	36.0	43.5	51.0	51.5	52.0	15.0	19.5	24.0	33.0	42.0
Alloprevotella sp. HMT308 (SP63)	308.0	336.0	364.0	431.0	498.0	1.0	1.0	1.0	1.0	1.0
Selenomonas sp. HMT149 (SP64)	1.0	1.0	1.0	1.5	2.0	2.0	2.0	2.0	2.5	3.0
Parvimonas micra (SP67)	8.0	26.0	44.0	64.0	84.0	1.0	1.0	1.0	1.0	1.0
Granulicatella adiacens (SP68)	299.0	347.0	395.0	413.5	432.0	29.0	56.0	83.0	86.0	89.0
Fusobacterium sp._Oral_Taxon_H27 (SP69)	1.0	1.5	2.0	19.5	37.0	1.0	1.0	1.0	1.0	1.0
Oribacterium sinus (SP70)	1.0	1.0	1.0	31.0	61.0	1.0	1.0	1.0	1.0	1.0
Selenomonas infelix (SP71)	1.0	3.0	5.0	5.0	5.0	11.0	12.0	13.0	16.5	20.0
Selenomonas sp._Oral_Taxon_G67 (SP72)	4.0	4.5	5.0	5.5	6.0	2.0	2.5	3.0	9.0	15.0
Parvimonas sp. HMT110 (SP75)	1.0	1.0	1.0	1.5	2.0	1.0	1.0	1.0	1.0	1.0
Gemella morbillorum (SP78)	53.0	59.5	66.0	133.0	200.0	1.0	1.0	1.0	1.5	2.0
Fusobacterium nucleatum (SP8)	2.0	2.5	3.0	15.0	27.0	1.0	1.0	1.0	1.0	1.0
Selenomonas sp._Oral_Taxon_G55 (SP80)	1.0	1.5	2.0	2.0	2.0	17.0	19.0	21.0	26.0	31.0
Schaalia sp. HMT180 (SP81)	1.0	2.0	3.0	3.0	3.0	1.0	1.5	2.0	2.0	2.0
Peptostreptococcaceae_[XI][G-7] [Eubacterium]_yurii_subsps._yurii_&_margaretiae (SP83)	1.0	1.0	1.0	1.5	2.0	1.0	1.0	1.0	1.0	1.0
Lautropia mirabilis (SP86)	1.0	1.0	1.0	1.0	1.0	18.0	67.0	116.0	147.5	179.0
Porphyromonas sp. HMT275 (SP88)	2.0	88.0	174.0	215.5	257.0	1.0	1.0	1.0	1.0	1.0
Fusobacterium hwasookii (SP9)	4.0	4.5	5.0	5.0	5.0	1.0	2.5	4.0	8.0	12.0
Streptococcus constellatus (SP93)	2.0	2.0	2.0	2.0	2.0	1.0	1.0	1.0	1.0	1.0
Selenomonas sp. HMT136 (SP99)	5.0	5.5	6.0	8.0	10.0	92.0	94.5	97.0	233.0	369.0
Abiotrophia defectiva_nov_97.500% (SPN1)	2.0	2.5	3.0	4.5	6.0	1.0	1.0	1.0	1.0	1.0
Selenomonas sp._Oral_Taxon_F85_nov_97.518% (SPN19)	1.0	1.0	1.0	1.5	2.0	4.0	5.5	7.0	14.5	22.0
Granulicatella adiacens_nov_97.857% (SPN2)	2.0	2.5	3.0	4.5	6.0	1.0	1.5	2.0	2.5	3.0
Selenomonas dianae_nov_97.527% (SPN3)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.5	2.0
Streptococcus sp. HMT056 nov_97.857% (SPN36)	3.0	4.5	6.0	7.0	8.0	9.0	10.5	12.0	15.5	19.0
Streptococcus gordonii_nov_97.857% (SPN4)	1.0	1.0	1.0	1.5	2.0	2.0	2.5	3.0	3.5	4.0
Streptococcus gordonii_nov_96.429% (SPN5)	1.0	1.0	1.0	1.0	1.0	1.0	2.0	3.0	4.5	6.0
Selenomonas artemidis_nov_97.857% (SPN57)	4.0	6.5	9.0	9.5	10.0	1.0	1.5	2.0	2.0	2.0
Selenomonas sp._Oral_Taxon_F87_nov_97.857% (SPN67)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.5	2.0
Prevotella melaninogenica_nov_97.865% (SPN73)	2.0	3.0	4.0	6.0	8.0	1.0	1.0	1.0	1.0	1.0
Prevotella pallens_nov_97.865% (SPN74)	3.0	3.5	4.0	5.0	6.0	1.0	1.0	1.0	1.0	1.0
Porphyromonas multispecies_spp15_2 (SPP15)	2.0	3.0	4.0	4.0	4.0	1.0	1.0	1.0	1.0	1.0
Porphyromonas multispecies_spp22_2 (SPP22)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.5	2.0
Veillonella multispecies_spp25_2 (SPP25)	1.0	2.0	3.0	4.5	6.0	1.0	1.5	2.0	5.0	8.0
Veillonella multispecies_spp26_3 (SPP26)	291.0	292.5	294.0	332.5	371.0	410.0	483.0	556.0	659.5	763.0
Aggregatibacter multispecies_spp29_2 (SPP29)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.5	2.0
Streptococcus multispecies_spp31_3 (SPP31)	1.0	1.0	1.0	1.5	2.0	17.0	17.0	17.0	30.0	43.0
Streptococcus multispecies_spp32_2 (SPP32)	2.0	2.5	3.0	8.5	14.0	2.0	2.5	3.0	4.0	5.0
Streptococcus multispecies_spp33_2 (SPP33)	1.0	1.0	1.0	2.5	4.0	1.0	1.0	1.0	1.5	2.0
Streptococcus multispecies_spp36_2 (SPP36)	1032.0	1332.0	1632.0	1716.0	1800.0	8.0	23.0	38.0	46.0	54.0
Streptococcus multispecies_spp37_2 (SPP37)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.5	4.0
Fusobacterium multispecies_spp38_2 (SPP38)	3.0	87.5	172.0	380.0	588.0	1.0	1.0	1.0	1.0	1.0
Fusobacterium multispecies_spp39_2 (SPP39)	1.0	1.5	2.0	12.5	23.0	1.0	1.0	1.0	1.0	1.0
Parvimonas multispecies_spp42_2 (SPP42)	7.0	13.5	20.0	150.5	281.0	1.0	1.5	2.0	2.0	2.0
Fusobacterium multispecies_spp43_3 (SPP43)	497.0	508.5	520.0	601.5	683.0	6.0	162.5	319.0	414.5	510.0
Fusobacterium multispecies_spp44_4 (SPP44)	15.0	28.5	42.0	102.0	162.0	2.0	37.5	73.0	95.5	118.0
Lancefieldella rimae (SPP46)	6.0	6.5	7.0	10.5	14.0	1.0	1.5	2.0	5.0	8.0
Streptococcus multispecies_spp47_2 (SPP47)	1.0	2.0	3.0	8.0	13.0	1.0	1.0	1.0	9.5	18.0
multigenus multispecies_spp48_2 (SPP48)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.5	2.0
Granulicatella multispecies_spp6_2 (SPP6)	11.0	11.5	12.0	15.0	18.0	1.0	2.0	3.0	4.0	5.0
multigenus multispecies_spp8_2 (SPP8)	3.0	3.5	4.0	5.5	7.0	1.0	2.0	3.0	3.5	4.0
Fusobacterium multispecies_sppn8_3_nov_97.436% (SPPN8)	1.0	1.5	2.0	3.0	4.0	1.0	1.0	1.0	1.0	1.0