Percentile	0.0	25.0	50.0	75.0	100.0	0.0	25.0	50.0	75.0	100.0
Group	Healthy-Control	Healthy-Control	Healthy-Control	Healthy-Control	Healthy-Control	Healthy-Dfx_1mM	Healthy-Dfx_1mM	Healthy-Dfx_1mM	Healthy-Dfx_1mM	Healthy-Dfx_1mM
Porphyromonas pasteri (SP10)	11.0	32.5	54.0	54.0	54.0	89.0	100.0	111.0	317.0	523.0
Selenomonas sp._Oral_Taxon_G67 (SP101)	5.0	8.0	11.0	12.0	13.0	4.0	5.5	7.0	7.5	8.0
Prevotella oralis (SP102)	2.0	5.5	9.0	17.5	26.0	9.0	12.5	16.0	17.0	18.0
Selenomonas sp. HMT481 (SP104)	3.0	12.5	22.0	24.0	26.0	11.0	14.0	17.0	18.0	19.0
Fretibacterium sp. HMT360 (SP105)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.5	2.0
Prevotella oulorum (SP108)	4.0	13.0	22.0	24.0	26.0	1.0	6.0	11.0	18.0	25.0
Selenomonas sp._Oral_Taxon_F29 (SP110)	20.0	25.0	30.0	33.0	36.0	21.0	23.0	25.0	31.5	38.0
Capnocytophaga sputigena (SP111)	12.0	13.5	15.0	25.5	36.0	1.0	3.5	6.0	13.5	21.0
Prevotella salivae (SP124)	3.0	4.0	5.0	7.0	9.0	1.0	2.0	3.0	3.5	4.0
Megasphaera micronuciformis (SP127)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	5.0	9.0
Selenomonas sp. HMT136 (SP130)	16.0	17.5	19.0	35.5	52.0	9.0	12.5	16.0	19.5	23.0
Slackia exigua (SP135)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.0	3.0
Streptococcus constellatus (SP136)	1.0	1.0	1.0	1.5	2.0	1.0	1.5	2.0	3.5	5.0
Porphyromonas sp. HMT275 (SP14)	1.0	1.0	1.0	1.5	2.0	3.0	82.0	161.0	222.5	284.0
Oribacterium sp. HMT078 (SP141)	1.0	1.0	1.0	1.0	1.0	1.0	1.5	2.0	2.0	2.0
Streptococcus pneumoniae (SP142)	7.0	7.5	8.0	8.0	8.0	8.0	11.5	15.0	18.0	21.0
Fusobacterium sp._Oral_Taxon_H27 (SP144)	1.0	3.5	6.0	7.0	8.0	1.0	1.5	2.0	25.5	49.0
Campylobacter curvus (SP145)	1.0	1.0	1.0	1.5	2.0	22.0	44.0	66.0	74.5	83.0
Selenomonas sp._Oral_Taxon_H64 (SP149)	3.0	3.0	3.0	6.0	9.0	1.0	2.5	4.0	4.0	4.0
Porphyromonas endodontalis (SP15)	1.0	1.0	1.0	1.5	2.0	1.0	1.0	1.0	1.0	1.0
Stomatobaculum longum (SP156)	1.0	2.0	3.0	3.5	4.0	1.0	1.0	1.0	1.0	1.0
Selenomonas sp._Oral_Taxon_G55 (SP158)	2.0	2.0	2.0	3.5	5.0	1.0	2.0	3.0	3.0	3.0
Alloprevotella sp. HMT308 (SP16)	146.0	167.5	189.0	237.0	285.0	197.0	244.5	292.0	429.5	567.0
Capnocytophaga sp. HMT864 (SP164)	7.0	8.5	10.0	13.5	17.0	7.0	8.0	9.0	30.0	51.0
Fusobacterium hwasookii (SP17)	6.0	12.0	18.0	19.5	21.0	8.0	15.5	23.0	28.0	33.0
Porphyromonas sp. HMT278 (SP18)	1.0	2.0	3.0	3.0	3.0	1.0	5.5	10.0	10.0	10.0
Streptococcus sp._Oral_Taxon_B66 (SP183)	2.0	2.5	3.0	5.0	7.0	1.0	1.5	2.0	2.0	2.0
Selenomonas sputigena (SP185)	1.0	2.0	3.0	4.5	6.0	2.0	2.0	2.0	2.5	3.0
Mycoplasma salivarium (SP186)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.0	3.0
Prevotella pallens (SP19)	792.0	901.0	1010.0	1595.5	2181.0	1288.0	1673.0	2058.0	2094.5	2131.0
Streptococcus sp._str._2136FAA (SP192)	1.0	1.0	1.0	1.0	1.0	1.0	2.0	3.0	3.5	4.0
Streptococcus mitis (SP2)	25.0	30.5	36.0	43.5	51.0	19.0	27.0	35.0	43.5	52.0
Prevotella maculosa (SP20)	1.0	1.0	1.0	2.5	4.0	1.0	1.0	1.0	1.0	1.0
Selenomonas sp._Oral_Taxon_H23 (SP200)	1.0	1.0	1.0	3.5	6.0	1.0	1.0	1.0	1.5	2.0
Prevotella intermedia (SP21)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.5	2.0
Oribacterium sinus (SP22)	1.0	1.0	1.0	3.0	5.0	1.0	1.0	1.0	10.0	19.0
Parvimonas micra (SP23)	37.0	40.0	43.0	44.0	45.0	52.0	52.5	53.0	61.0	69.0
Streptococcus sp. HMT064 (SP24)	3.0	4.0	5.0	10.5	16.0	11.0	14.0	17.0	25.5	34.0
Prevotella buccae (SP25)	2.0	3.0	4.0	5.5	7.0	3.0	3.5	4.0	6.5	9.0
Streptococcus sp. HMT056 (SP26)	1.0	10.5	20.0	21.5	23.0	9.0	12.5	16.0	17.5	19.0
Centipeda sp._Oral_Taxon_D18 (SP27)	1.0	2.5	4.0	4.5	5.0	2.0	6.0	10.0	10.5	11.0
Granulicatella adiacens (SP28)	72.0	101.0	130.0	134.0	138.0	113.0	139.0	165.0	206.5	248.0
Streptococcus sp._str._C300 (SP29)	82.0	86.5	91.0	160.0	229.0	169.0	221.0	273.0	296.0	319.0
Gemella morbillorum (SP31)	29.0	34.5	40.0	69.0	98.0	8.0	11.5	15.0	54.0	93.0
Bacteroidales_[G-2] bacterium HMT274 (SP32)	47.0	108.0	169.0	183.0	197.0	77.0	226.5	376.0	472.5	569.0
Capnocytophaga gingivalis (SP33)	14.0	27.0	40.0	44.0	48.0	9.0	17.5	26.0	29.0	32.0
Prevotella melaninogenica (SP34)	123.0	136.5	150.0	250.0	350.0	242.0	304.5	367.0	425.5	484.0
Campylobacter showae (SP35)	6.0	10.0	14.0	19.0	24.0	8.0	13.0	18.0	23.5	29.0
Eikenella corrodens (SP37)	12.0	18.5	25.0	25.0	25.0	20.0	22.0	24.0	25.0	26.0
Campylobacter concisus (SP38)	17.0	22.5	28.0	31.0	34.0	26.0	60.0	94.0	102.5	111.0
Prevotella denticola (SP39)	1.0	14.5	28.0	41.0	54.0	17.0	35.0	53.0	77.0	101.0
Fusobacterium nucleatum (SP4)	1.0	1.5	2.0	2.5	3.0	1.0	1.5	2.0	2.5	3.0
Haemophilus parainfluenzae (SP40)	16.0	24.5	33.0	35.5	38.0	15.0	26.5	38.0	42.0	46.0
Streptococcus oralis_subsp._dentisani_clade_058 (SP41)	2.0	2.5	3.0	4.0	5.0	1.0	1.5	2.0	6.0	10.0
Streptococcus oralis_subsp._tigurinus_clade_071 (SP42)	70.0	101.5	133.0	136.5	140.0	111.0	173.5	236.0	310.5	385.0
Alloprevotella rava (SP43)	1.0	1.0	1.0	1.5	2.0	1.0	1.0	1.0	1.0	1.0
Streptococcus gordonii (SP44)	49.0	52.0	55.0	58.5	62.0	10.0	32.5	55.0	59.5	64.0
Selenomonas sp. HMT146 (SP47)	45.0	62.0	79.0	86.5	94.0	32.0	46.5	61.0	72.5	84.0
Streptococcus oralis_subsp._tigurinus_clade_070 (SP48)	1.0	1.0	1.0	2.0	3.0	1.0	1.0	1.0	1.5	2.0
Anaeroglobus geminatus (SP49)	1.0	5.5	10.0	25.5	41.0	6.0	11.0	16.0	30.0	44.0
Fusobacterium nucleatum_subsp._vincentii (SP52)	1.0	2.5	4.0	5.5	7.0	1.0	1.0	1.0	2.5	4.0
Alloprevotella tannerae (SP53)	1.0	1.0	1.0	57.0	113.0	6.0	7.0	8.0	36.0	64.0
Streptococcus cristatus_clade_578 (SP56)	227.0	302.0	377.0	488.0	599.0	338.0	422.0	506.0	568.0	630.0
Selenomonas sp._Oral_Taxon_G51 (SP61)	1.0	1.5	2.0	2.0	2.0	1.0	1.5	2.0	3.0	4.0
Selenomonas sp. HMT892 (SP62)	2.0	3.0	4.0	5.0	6.0	2.0	2.0	2.0	2.0	2.0
Peptostreptococcaceae_[XI][G-7] [Eubacterium]_yurii_subsps._yurii_&_margaretiae (SP64)	1.0	1.0	1.0	1.5	2.0	1.0	1.0	1.0	1.0	1.0
Streptococcus chosunense (SP68)	104.0	126.0	148.0	166.0	184.0	82.0	152.0	222.0	302.0	382.0
Bacteroidales_[G-2] sp._Oral_Taxon_274 (SP69)	11.0	13.0	15.0	36.0	57.0	2.0	6.0	10.0	15.5	21.0
Veillonella parvula (SP7)	13.0	13.5	14.0	32.5	51.0	7.0	10.5	14.0	28.5	43.0
Selenomonas dianae (SP70)	7.0	17.5	28.0	28.0	28.0	21.0	22.0	23.0	31.0	39.0
Solobacterium moorei (SP71)	4.0	7.0	10.0	37.0	64.0	4.0	8.5	13.0	17.0	21.0
Fusobacterium sp. HMT204 (SP72)	5.0	14.0	23.0	113.0	203.0	1.0	1.0	1.0	1.5	2.0
Selenomonas infelix (SP74)	8.0	24.0	40.0	52.0	64.0	34.0	40.0	46.0	49.5	53.0
Parvimonas sp. HMT110 (SP76)	1.0	1.0	1.0	1.5	2.0	1.0	1.0	1.0	1.0	1.0
Porphyromonas catoniae (SP77)	23.0	23.5	24.0	31.5	39.0	4.0	4.0	4.0	7.0	10.0
Catonella morbi (SP78)	1.0	1.0	1.0	1.5	2.0	1.0	1.0	1.0	1.0	1.0
Schaalia sp. HMT180 (SP79)	2.0	3.0	4.0	4.5	5.0	1.0	1.5	2.0	3.0	4.0
Abiotrophia defectiva (SP81)	3.0	4.5	6.0	9.5	13.0	6.0	6.0	6.0	13.5	21.0
Selenomonas flueggei (SP82)	2.0	3.0	4.0	4.0	4.0	1.0	2.5	4.0	4.5	5.0
Veillonella sp._Oral_Taxon_G61 (SP83)	3.0	3.5	4.0	13.5	23.0	8.0	12.5	17.0	20.0	23.0
Selenomonas sp. HMT149 (SP84)	1.0	1.5	2.0	3.5	5.0	1.0	1.0	1.0	4.5	8.0
Prevotella sp. HMT317 (SP85)	3.0	9.5	16.0	22.0	28.0	2.0	4.0	6.0	7.5	9.0
Streptococcus pseudopneumoniae (SP86)	3.0	3.0	3.0	3.5	4.0	4.0	4.0	4.0	6.5	9.0
Dialister invisus (SP88)	1.0	1.0	1.0	4.5	8.0	3.0	3.0	3.0	3.0	3.0
Fusobacterium periodonticum (SP89)	2.0	2.0	2.0	10.0	18.0	1.0	2.0	3.0	5.5	8.0
Veillonella dispar (SP9)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.0	3.0
Streptococcus sanguinis (SP90)	35.0	35.5	36.0	55.0	74.0	23.0	30.0	37.0	59.5	82.0
Leptotrichia sp. HMT215 (SP91)	1.0	10.0	19.0	36.5	54.0	1.0	1.0	1.0	1.0	1.0
Streptococcus anginosus (SP96)	1.0	1.0	1.0	1.5	2.0	1.0	1.0	1.0	1.0	1.0
Prevotella melaninogenica_nov_97.865% (SPN10)	4.0	5.5	7.0	9.0	11.0	7.0	13.0	19.0	24.0	29.0
Selenomonas artemidis_nov_97.857% (SPN17)	1.0	1.5	2.0	2.0	2.0	1.0	1.0	1.0	1.0	1.0
Abiotrophia defectiva_nov_97.491% (SPN2)	1.0	1.0	1.0	3.0	5.0	1.0	1.0	1.0	3.5	6.0
Fusobacterium hwasookii_nov_97.802% (SPN42)	2.0	3.5	5.0	9.0	13.0	4.0	6.5	9.0	9.5	10.0
Fusobacterium hwasookii_nov_96.774% (SPN46)	1.0	1.5	2.0	2.0	2.0	1.0	1.0	1.0	4.5	8.0
Fusobacterium hwasookii_nov_94.139% (SPN57)	1.0	1.0	1.0	1.5	2.0	1.0	1.5	2.0	2.5	3.0
Prevotella pallens_nov_97.865% (SPN61)	1.0	2.5	4.0	4.5	5.0	3.0	6.5	10.0	14.0	18.0
Streptococcus oralis_subsp._dentisani_clade_058_nov_97.857% (SPN63)	2.0	3.5	5.0	5.0	5.0	1.0	2.0	3.0	5.0	7.0
Fusobacterium multispecies_spp17_4 (SPP17)	425.0	427.5	430.0	627.0	824.0	120.0	521.5	923.0	928.5	934.0
Streptococcus multispecies_spp20_3 (SPP20)	1.0	2.0	3.0	4.0	5.0	2.0	3.0	4.0	4.5	5.0
Streptococcus multispecies_spp21_2 (SPP21)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.5	2.0
Granulicatella multispecies_spp23_2 (SPP23)	3.0	5.0	7.0	8.0	9.0	3.0	3.5	4.0	6.5	9.0
Streptococcus multispecies_spp24_2 (SPP24)	462.0	492.5	523.0	529.0	535.0	790.0	806.5	823.0	854.5	886.0
Fusobacterium multispecies_spp26_2 (SPP26)	6.0	11.5	17.0	26.0	35.0	4.0	15.0	26.0	57.0	88.0
Fusobacterium multispecies_spp27_2 (SPP27)	1.0	1.5	2.0	2.5	3.0	1.0	1.0	1.0	12.5	24.0
Fusobacterium multispecies_spp30_2 (SPP30)	1.0	1.0	1.0	33.5	66.0	1.0	1.0	1.0	1.5	2.0
Fusobacterium multispecies_spp31_2 (SPP31)	2.0	2.5	3.0	9.0	15.0	3.0	3.0	3.0	11.0	19.0
Fusobacterium multispecies_spp32_3 (SPP32)	753.0	867.5	982.0	1510.0	2038.0	213.0	871.5	1530.0	1676.0	1822.0
Selenomonas multispecies_spp35_2 (SPP35)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.5	2.0
Veillonella multispecies_spp38_3 (SPP38)	194.0	250.5	307.0	422.0	537.0	378.0	400.5	423.0	529.5	636.0
Veillonella multispecies_spp39_2 (SPP39)	1.0	2.0	3.0	5.0	7.0	1.0	2.0	3.0	4.5	6.0
Porphyromonas multispecies_spp4_2 (SPP4)	1.0	1.0	1.0	1.0	1.0	4.0	5.5	7.0	10.0	13.0
Lancefieldella rimae (SPP40)	5.0	7.5	10.0	14.5	19.0	11.0	11.0	11.0	22.0	33.0
multigenus multispecies_spp5_2 (SPP5)	1.0	1.5	2.0	3.0	4.0	1.0	1.5	2.0	3.5	5.0
Fusobacterium multispecies_sppn2_3_nov_96.970% (SPPN2)	1.0	1.0	1.0	1.0	1.0	1.0	2.0	3.0	6.0	9.0