Percentile	0.0	25.0	50.0	75.0	100.0	0.0	25.0	50.0	75.0	100.0
Group	Perio-Control	Perio-Control	Perio-Control	Perio-Control	Perio-Control	Perio-Dfx_2mM	Perio-Dfx_2mM	Perio-Dfx_2mM	Perio-Dfx_2mM	Perio-Dfx_2mM
Porphyromonas pasteri (SP10)	930.0	984.0	1038.0	1196.0	1354.0	709.0	742.0	775.0	1053.5	1332.0
Selenomonas sp._Oral_Taxon_G67 (SP101)	2.0	2.5	3.0	4.5	6.0	3.0	3.5	4.0	5.5	7.0
Prevotella oralis (SP102)	4.0	8.0	12.0	12.5	13.0	1.0	3.5	6.0	6.5	7.0
Selenomonas sp. HMT481 (SP104)	1.0	1.5	2.0	2.0	2.0	1.0	1.0	1.0	1.0	1.0
Fretibacterium sp. HMT360 (SP105)	27.0	28.5	30.0	41.5	53.0	40.0	40.0	40.0	47.5	55.0
Selenomonas sp._Oral_Taxon_E83 (SP106)	2.0	2.5	3.0	3.0	3.0	2.0	2.5	3.0	5.5	8.0
Prevotella oulorum (SP108)	2.0	2.5	3.0	6.5	10.0	3.0	5.0	7.0	8.5	10.0
Actinomyces odontolyticus (SP109)	3.0	4.0	5.0	6.0	7.0	2.0	7.0	12.0	15.0	18.0
Veillonellaceae_[G-1] bacterium HMT129 (SP11)	1.0	1.5	2.0	2.0	2.0	1.0	2.5	4.0	5.0	6.0
Selenomonas sp._Oral_Taxon_F29 (SP110)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.5	2.0
Capnocytophaga sputigena (SP111)	4.0	4.0	4.0	5.0	6.0	2.0	2.5	3.0	4.0	5.0
Prevotella baroniae (SP119)	5.0	6.0	7.0	11.0	15.0	7.0	9.5	12.0	14.0	16.0
Porphyromonas gingivalis (SP12)	1.0	2.0	3.0	15.0	27.0	13.0	15.5	18.0	21.5	25.0
Megasphaera micronuciformis (SP127)	1.0	1.0	1.0	1.5	2.0	2.0	2.5	3.0	7.5	12.0
Selenomonas sp. HMT136 (SP130)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.5	2.0
Slackia exigua (SP135)	1.0	1.0	1.0	1.0	1.0	2.0	2.5	3.0	4.0	5.0
Streptococcus constellatus (SP136)	2.0	2.0	2.0	3.5	5.0	1.0	2.0	3.0	5.0	7.0
Porphyromonas sp. HMT275 (SP14)	5.0	7.0	9.0	20.0	31.0	11.0	13.0	15.0	26.0	37.0
Oribacterium sp. HMT078 (SP141)	1.0	1.0	1.0	2.5	4.0	2.0	2.5	3.0	4.5	6.0
Streptococcus pneumoniae (SP142)	1.0	1.0	1.0	1.5	2.0	1.0	1.0	1.0	1.0	1.0
Dialister pneumosintes (SP143)	1.0	1.5	2.0	6.0	10.0	1.0	1.0	1.0	8.0	15.0
Fusobacterium sp._Oral_Taxon_H27 (SP144)	1.0	1.0	1.0	4.5	8.0	2.0	2.5	3.0	3.5	4.0
Selenomonas sp._Oral_Taxon_H64 (SP149)	1.0	1.0	1.0	1.0	1.0	1.0	1.5	2.0	2.0	2.0
Porphyromonas endodontalis (SP15)	6.0	124.5	243.0	558.5	874.0	217.0	241.0	265.0	310.5	356.0
Stomatobaculum longum (SP156)	1.0	1.0	1.0	1.5	2.0	1.0	2.0	3.0	3.5	4.0
Selenomonas sp._Oral_Taxon_G55 (SP158)	1.0	1.5	2.0	2.0	2.0	1.0	1.5	2.0	2.0	2.0
Alloprevotella sp. HMT308 (SP16)	8.0	29.5	51.0	62.5	74.0	4.0	15.5	27.0	30.5	34.0
Selenomonas sp. HMT919 (SP169)	10.0	10.5	11.0	12.0	13.0	3.0	6.5	10.0	10.5	11.0
Fusobacterium hwasookii (SP17)	8.0	10.0	12.0	13.0	14.0	14.0	14.0	14.0	15.5	17.0
Porphyromonas sp. HMT278 (SP18)	290.0	519.5	749.0	779.0	809.0	463.0	465.0	467.0	643.0	819.0
Selenomonas sputigena (SP185)	2.0	3.0	4.0	7.0	10.0	3.0	3.0	3.0	3.0	3.0
Mycoplasma salivarium (SP186)	1.0	1.0	1.0	2.5	4.0	2.0	2.0	2.0	4.0	6.0
Prevotella pallens (SP19)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.0	3.0
Prevotella sp. HMT376 (SP190)	1.0	1.5	2.0	2.5	3.0	1.0	1.0	1.0	2.5	4.0
Prevotella sp. HMT301 (SP191)	2.0	3.0	4.0	4.5	5.0	1.0	1.0	1.0	2.5	4.0
Streptococcus sp._str._2136FAA (SP192)	2.0	2.0	2.0	2.5	3.0	1.0	1.0	1.0	1.0	1.0
Streptococcus mitis (SP2)	1.0	1.5	2.0	2.5	3.0	1.0	1.0	1.0	1.0	1.0
Prevotella maculosa (SP20)	20.0	23.5	27.0	28.5	30.0	11.0	15.5	20.0	20.5	21.0
Selenomonas sp._Oral_Taxon_H23 (SP200)	1.0	1.0	1.0	1.5	2.0	1.0	1.5	2.0	3.5	5.0
Prevotella intermedia (SP21)	146.0	167.0	188.0	273.0	358.0	47.0	68.5	90.0	139.0	188.0
Oribacterium sinus (SP22)	8.0	14.0	20.0	24.5	29.0	16.0	17.5	19.0	20.0	21.0
Parvimonas micra (SP23)	6.0	8.5	11.0	18.0	25.0	6.0	8.0	10.0	11.5	13.0
Streptococcus sp. HMT064 (SP24)	6.0	6.5	7.0	8.5	10.0	1.0	2.0	3.0	4.5	6.0
Prevotella buccae (SP25)	4.0	5.0	6.0	6.0	6.0	4.0	4.5	5.0	5.0	5.0
Streptococcus sp. HMT056 (SP26)	1.0	1.0	1.0	1.5	2.0	1.0	1.0	1.0	1.0	1.0
Centipeda sp._Oral_Taxon_D18 (SP27)	1.0	1.0	1.0	1.5	2.0	1.0	1.0	1.0	1.0	1.0
Granulicatella adiacens (SP28)	10.0	24.0	38.0	64.5	91.0	13.0	15.0	17.0	29.0	41.0
Streptococcus sp._str._C300 (SP29)	5.0	6.0	7.0	7.5	8.0	3.0	5.5	8.0	9.0	10.0
Gemella morbillorum (SP31)	12.0	13.0	14.0	17.0	20.0	14.0	22.5	31.0	48.0	65.0
Bacteroidales_[G-2] bacterium HMT274 (SP32)	28.0	29.5	31.0	36.0	41.0	7.0	8.5	10.0	14.5	19.0
Capnocytophaga gingivalis (SP33)	7.0	7.5	8.0	8.5	9.0	5.0	8.0	11.0	13.0	15.0
Prevotella melaninogenica (SP34)	2.0	2.5	3.0	6.0	9.0	1.0	1.5	2.0	6.5	11.0
Campylobacter showae (SP35)	1.0	1.0	1.0	1.5	2.0	1.0	1.0	1.0	1.5	2.0
Eikenella corrodens (SP37)	10.0	12.5	15.0	15.0	15.0	14.0	17.0	20.0	22.0	24.0
Campylobacter concisus (SP38)	5.0	7.0	9.0	9.5	10.0	7.0	9.5	12.0	15.5	19.0
Prevotella denticola (SP39)	1.0	2.5	4.0	19.0	34.0	11.0	12.0	13.0	23.5	34.0
Fusobacterium nucleatum (SP4)	1.0	1.0	1.0	2.0	3.0	1.0	1.0	1.0	1.0	1.0
Haemophilus parainfluenzae (SP40)	1.0	1.0	1.0	2.5	4.0	1.0	1.0	1.0	1.5	2.0
Streptococcus oralis_subsp._dentisani_clade_058 (SP41)	2.0	3.0	4.0	4.0	4.0	3.0	3.5	4.0	7.5	11.0
Streptococcus oralis_subsp._tigurinus_clade_071 (SP42)	11.0	13.0	15.0	17.5	20.0	6.0	9.5	13.0	14.0	15.0
Alloprevotella rava (SP43)	263.0	306.5	350.0	634.5	919.0	527.0	552.5	578.0	653.0	728.0
Streptococcus gordonii (SP44)	3.0	6.5	10.0	14.5	19.0	5.0	6.0	7.0	9.5	12.0
Selenomonas sp. HMT146 (SP47)	1.0	1.0	1.0	1.5	2.0	1.0	1.0	1.0	1.0	1.0
Streptococcus oralis_subsp._tigurinus_clade_070 (SP48)	5.0	8.0	11.0	15.5	20.0	7.0	9.5	12.0	13.0	14.0
Anaeroglobus geminatus (SP49)	1.0	3.5	6.0	13.5	21.0	9.0	12.0	15.0	16.5	18.0
Fusobacterium nucleatum_subsp._vincentii (SP52)	3.0	5.5	8.0	8.5	9.0	3.0	5.5	8.0	10.0	12.0
Alloprevotella tannerae (SP53)	30.0	51.5	73.0	99.5	126.0	52.0	61.0	70.0	125.0	180.0
Prevotella marshii (SP54)	21.0	35.5	50.0	54.0	58.0	14.0	20.5	27.0	40.0	53.0
Streptococcus cristatus_clade_578 (SP56)	26.0	29.5	33.0	61.5	90.0	36.0	42.0	48.0	71.5	95.0
Selenomonas sp._Oral_Taxon_G51 (SP61)	1.0	2.0	3.0	3.5	4.0	1.0	1.0	1.0	1.5	2.0
Campylobacter sp._Oral_Taxon_E65 (SP63)	2.0	2.0	2.0	2.5	3.0	38.0	59.0	80.0	98.5	117.0
Peptostreptococcaceae_[XI][G-7] [Eubacterium]_yurii_subsps._yurii_&_margaretiae (SP64)	64.0	65.5	67.0	72.5	78.0	35.0	49.5	64.0	66.5	69.0
Prevotella sp. HMT314 (SP65)	11.0	16.0	21.0	23.5	26.0	3.0	8.5	14.0	33.0	52.0
Streptococcus chosunense (SP68)	6.0	8.0	10.0	17.5	25.0	7.0	8.0	9.0	12.0	15.0
Veillonella parvula (SP7)	36.0	41.5	47.0	55.5	64.0	22.0	29.5	37.0	43.0	49.0
Selenomonas dianae (SP70)	27.0	28.5	30.0	42.5	55.0	32.0	33.5	35.0	41.5	48.0
Solobacterium moorei (SP71)	111.0	131.0	151.0	156.0	161.0	76.0	83.0	90.0	110.5	131.0
Fusobacterium sp. HMT204 (SP72)	1.0	4.5	8.0	12.0	16.0	4.0	4.0	4.0	8.0	12.0
Alloprevotella sp. HMT473 (SP73)	1.0	168.5	336.0	543.0	750.0	14.0	17.5	21.0	268.0	515.0
Selenomonas infelix (SP74)	2.0	2.5	3.0	5.0	7.0	5.0	5.5	6.0	6.0	6.0
Fusobacterium sp._Oral_Taxon_D95 (SP75)	11.0	14.5	18.0	25.5	33.0	18.0	19.0	20.0	28.0	36.0
Parvimonas sp. HMT110 (SP76)	4.0	28.0	52.0	78.0	104.0	1.0	1.5	2.0	3.5	5.0
Catonella morbi (SP78)	1.0	10.0	19.0	112.0	205.0	20.0	76.0	132.0	183.0	234.0
Schaalia sp. HMT180 (SP79)	1.0	1.0	1.0	1.0	1.0	1.0	1.0	1.0	2.5	4.0
Streptococcus sp._Oral_Taxon_F53 (SP80)	4.0	4.0	4.0	7.0	10.0	4.0	6.5	9.0	9.5	10.0
Abiotrophia defectiva (SP81)	3.0	3.0	3.0	5.0	7.0	4.0	6.0	8.0	9.5	11.0
Selenomonas flueggei (SP82)	2.0	4.0	6.0	7.0	8.0	1.0	1.5	2.0	3.5	5.0
Veillonella sp._Oral_Taxon_G61 (SP83)	1.0	2.5	4.0	4.5	5.0	1.0	1.0	1.0	2.0	3.0
Selenomonas sp. HMT149 (SP84)	1.0	1.0	1.0	2.5	4.0	1.0	1.0	1.0	1.5	2.0
Prevotella sp. HMT317 (SP85)	3.0	10.5	18.0	24.0	30.0	6.0	8.0	10.0	10.0	10.0
Streptococcus cristatus (SP87)	1.0	1.5	2.0	3.5	5.0	1.0	1.5	2.0	2.5	3.0
Dialister invisus (SP88)	52.0	62.0	72.0	78.0	84.0	65.0	67.0	69.0	101.5	134.0
Fusobacterium periodonticum (SP89)	6.0	6.5	7.0	10.0	13.0	7.0	8.0	9.0	10.0	11.0
Veillonella dispar (SP9)	8.0	8.5	9.0	9.5	10.0	4.0	5.5	7.0	7.5	8.0
Streptococcus sanguinis (SP90)	15.0	19.0	23.0	25.5	28.0	15.0	16.0	17.0	25.5	34.0
Leptotrichia sp. HMT215 (SP91)	1.0	1.5	2.0	3.5	5.0	1.0	1.0	1.0	2.5	4.0
Streptococcus anginosus (SP96)	2.0	3.0	4.0	5.5	7.0	2.0	3.0	4.0	4.0	4.0
Prevotella sp. HMT472 (SP98)	2.0	3.5	5.0	8.5	12.0	1.0	1.0	1.0	1.0	1.0
Alloprevotella rava_nov_97.865% (SPN1)	1.0	1.0	1.0	1.0	1.0	2.0	3.0	4.0	5.0	6.0
Selenomonas artemidis_nov_97.857% (SPN17)	3.0	3.0	3.0	4.0	5.0	3.0	3.5	4.0	5.0	6.0
Selenomonas dianae_nov_97.527% (SPN22)	10.0	11.0	12.0	13.5	15.0	9.0	9.5	10.0	14.5	19.0
Alloprevotella sp. HMT473 nov_97.153% (SPN31)	2.0	5.5	9.0	15.0	21.0	1.0	4.0	7.0	8.5	10.0
Fusobacterium hwasookii_nov_97.802% (SPN42)	2.0	3.0	4.0	4.0	4.0	1.0	2.0	3.0	3.5	4.0
Fusobacterium hwasookii_nov_96.774% (SPN46)	2.0	2.5	3.0	3.0	3.0	1.0	1.5	2.0	3.5	5.0
Selenomonas sp. HMT481 nov_96.786% (SPN54)	9.0	9.0	9.0	9.0	9.0	4.0	5.5	7.0	7.5	8.0
Fusobacterium hwasookii_nov_94.139% (SPN57)	1.0	3.0	5.0	5.5	6.0	2.0	2.0	2.0	4.0	6.0
Porphyromonas pasteri_nov_97.865% (SPN62)	1.0	1.0	1.0	6.5	12.0	1.0	4.5	8.0	10.0	12.0
Streptococcus oralis_subsp._dentisani_clade_058_nov_97.857% (SPN63)	1.0	1.0	1.0	1.5	2.0	1.0	1.0	1.0	1.0	1.0
Porphyromonas endodontalis_nov_97.865% (SPN64)	1.0	1.0	1.0	2.5	4.0	2.0	4.0	6.0	6.0	6.0
Porphyromonas sp. HMT278 nov_97.865% (SPN65)	2.0	2.5	3.0	3.5	4.0	3.0	3.0	3.0	3.5	4.0
Bacteroides heparinolyticus_nov_95.745% (SPN7)	34.0	39.5	45.0	61.5	78.0	58.0	63.5	69.0	70.5	72.0
Selenomonas multispecies_spp11_2 (SPP11)	2.0	2.5	3.0	4.5	6.0	2.0	2.5	3.0	4.0	5.0
multigenus multispecies_spp15_2 (SPP15)	1.0	1.0	1.0	1.5	2.0	5.0	5.0	5.0	5.5	6.0
Fusobacterium multispecies_spp17_4 (SPP17)	11.0	13.0	15.0	16.5	18.0	4.0	6.0	8.0	9.0	10.0
Streptococcus multispecies_spp20_3 (SPP20)	356.0	404.5	453.0	594.0	735.0	283.0	465.5	648.0	655.0	662.0
Streptococcus multispecies_spp21_2 (SPP21)	5.0	6.0	7.0	7.0	7.0	1.0	1.5	2.0	4.0	6.0
Granulicatella multispecies_spp23_2 (SPP23)	12.0	15.5	19.0	19.5	20.0	2.0	10.0	18.0	19.5	21.0
Streptococcus multispecies_spp24_2 (SPP24)	3.0	3.0	3.0	6.0	9.0	2.0	2.0	2.0	3.5	5.0
Fusobacterium multispecies_spp26_2 (SPP26)	27.0	28.0	29.0	40.0	51.0	88.0	88.5	89.0	95.5	102.0
Fusobacterium multispecies_spp27_2 (SPP27)	2.0	3.5	5.0	6.5	8.0	1.0	1.0	1.0	2.0	3.0
Fusobacterium multispecies_spp30_2 (SPP30)	2.0	3.0	4.0	4.5	5.0	1.0	1.5	2.0	4.0	6.0
Fusobacterium multispecies_spp31_2 (SPP31)	34.0	36.5	39.0	58.0	77.0	24.0	36.5	49.0	49.0	49.0
Fusobacterium multispecies_spp32_3 (SPP32)	1332.0	1484.5	1637.0	2093.5	2550.0	1337.0	1639.0	1941.0	1991.5	2042.0
Fusobacterium multispecies_spp33_2 (SPP33)	1.0	2.0	3.0	4.0	5.0	1.0	4.0	7.0	10.0	13.0
Streptococcus multispecies_spp34_2 (SPP34)	1.0	4.5	8.0	15.5	23.0	10.0	12.0	14.0	16.0	18.0
Selenomonas multispecies_spp35_2 (SPP35)	8.0	9.5	11.0	15.5	20.0	11.0	12.5	14.0	20.0	26.0
multigenus multispecies_spp36_2 (SPP36)	162.0	163.5	165.0	167.5	170.0	75.0	107.5	140.0	154.5	169.0
Veillonella multispecies_spp38_3 (SPP38)	54.0	57.0	60.0	61.0	62.0	25.0	35.0	45.0	48.0	51.0
Veillonella multispecies_spp39_2 (SPP39)	9.0	10.5	12.0	14.5	17.0	3.0	3.5	4.0	8.5	13.0
Lancefieldella rimae (SPP40)	22.0	23.5	25.0	30.0	35.0	8.0	15.0	22.0	22.0	22.0
multigenus multispecies_spp5_2 (SPP5)	3.0	4.5	6.0	6.5	7.0	4.0	4.0	4.0	5.5	7.0
Capnocytophaga multispecies_spp6_2 (SPP6)	1.0	2.5	4.0	4.5	5.0	2.0	2.0	2.0	3.0	4.0
Porphyromonas multispecies_spp8_2 (SPP8)	2.0	31.0	60.0	852.0	1644.0	275.0	1108.5	1942.0	2056.5	2171.0
Streptococcus multispecies_sppn1_2_nov_97.509% (SPPN1)	2.0	2.5	3.0	5.0	7.0	1.0	3.0	5.0	5.5	6.0
Fusobacterium multispecies_sppn2_3_nov_96.970% (SPPN2)	6.0	7.0	8.0	9.0	10.0	6.0	7.0	8.0	17.0	26.0
Porphyromonas multispecies_sppn3_2_nov_97.865% (SPPN3)	1.0	1.0	1.0	3.0	5.0	2.0	3.0	4.0	4.0	4.0
multigenus multispecies_sppn7_2_nov_96.071% (SPPN7)	2.0	3.5	5.0	6.5	8.0	2.0	2.5	3.0	8.5	14.0
Fusobacterium multispecies_sppn9_3_nov_96.337% (SPPN9)	1.0	1.0	1.0	6.5	12.0	1.0	1.5	2.0	5.0	8.0