Table of Content
I.Project Summary
II.Workflow Checklist
III.NGS Sequencing Results
IV.Complete Report Download
V.Raw Sequence Data Download
VI.Analysis - DADA2 Read Processing
 Sample Meta Info
 Read Count by Sample
VII.Analysis - Read Taxonomy Assignment
 Taxonomy Barplots
VIII.Analysis - Alpha Diversity
IX.Analysis - Beta Diversity
X.Analysis - Differential Abundance
 ANCOM Result
 LEfSe Result
XI.Analysis - Heatmap Profile
XII.Analysis - Network Association
XIII.Disclaimer

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FOMC Service Report

16S rRNA Gene V1V3 Amplicon Sequencing

Version V1.52

Version History

The Forsyth Institute, Cambridge, MA, USA
May 18, 2026

Project ID: FOMC28914_2

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I. Project Summary

Project FOMC28914_2 services include NGS sequencing of the V1V3 region of the 16S rRNA gene amplicons from the samples. First and foremost, please download this report, as well as the sequence raw data from the download links provided below. These links will expire after 60 days. We cannot guarantee the availability of your data after 60 days.

Full Bioinformatics analysis service was requested. We provide many analyses, starting from the raw sequence quality and noise filtering, pair reads merging, as well as chimera filtering for the sequences, using the DADA2 denosing algorithm and pipeline.

We also provide many downstream analyses such as taxonomy assignment, alpha and beta diversity analyses, and differential abundance analysis.

For taxonomy assignment, most informative would be the taxonomy barplots. We provide an interactive barplots to show the relative abundance of microbes at different taxonomy levels (from Phylum to species) that you can choose.

If you specify which groups of samples you want to compare for differential abundance, we provide both ANCOM and LEfSe differential abundance analysis.

 

II. Workflow Checklist

☑1.Sample Received
☑2.Sample Quality Evaluated
☑3.Sample Prepared for Sequencing
☑4.Next-Gen Sequencing
☑5.Sequence Quality Check
☑6.Absolute Abundance
☑7.Report and Raw Sequence Data Available for Download
☑8.Bioinformatics Analysis - Reads Processing (DADA2 Quality Trimming, Denoising, Paired Reads Merging)
☑9.Bioinformatics Analysis - Reads Taxonomy Assignment
☑10.Bioinformatics Analysis - Alpha Diversity Analysis
☑11.Bioinformatics Analysis - Beta Diversity Analysis
☑12.Bioinformatics Analysis - Differential Abundance Analysis
☑13.Bioinformatics Analysis - Heatmap Profile
☑14.Bioinformatics Analysis - Network Association
 

III. NGS Sequencing

The samples were processed and analyzed with the ZymoBIOMICS® Service: Targeted Metagenomic Sequencing (Zymo Research, Irvine, CA).

DNA Extraction: If DNA extraction was performed, the following DNA extraction kit was used according to the manufacturer’s instructions:

☑ZymoBIOMICS®-96 MagBead DNA Kit (Zymo Research, Irvine, CA)
☐N/A (DNA Extraction Not Performed)
Elution Volume: 50µL
Additional Notes: NA

Targeted Library Preparation: The DNA samples were prepared for targeted sequencing with the Quick-16S™ NGS Library Prep Kit (Zymo Research, Irvine, CA). These primers were custom designed by Zymo Research to provide the best coverage of the 16S gene while maintaining high sensitivity. The primer sets used in this project are marked below:

☐Quick-16S™ Primer Set V1-V2 (Zymo Research, Irvine, CA)
☑Quick-16S™ Primer Set V1-V3 (Zymo Research, Irvine, CA)
☐Quick-16S™ Primer Set V3-V4 (Zymo Research, Irvine, CA)
☐Quick-16S™ Primer Set V4 (Zymo Research, Irvine, CA)
☐Quick-16S™ Primer Set V6-V8 (Zymo Research, Irvine, CA)
Additional Notes: NA

The sequencing library was prepared using an innovative library preparation process in which PCR reactions were performed in real-time PCR machines to control cycles and therefore limit PCR chimera formation. The final PCR products were quantified with qPCR fluorescence readings and pooled together based on equal molarity. The final pooled library was cleaned up with the Select-a-Size DNA Clean & Concentrator™ (Zymo Research, Irvine, CA), then quantified with TapeStation® (Agilent Technologies, Santa Clara, CA) and Qubit® (Thermo Fisher Scientific, Waltham, WA).

Control Samples: The ZymoBIOMICS® Microbial Community Standard (Zymo Research, Irvine, CA) was used as a positive control for each DNA extraction, if performed. The ZymoBIOMICS® Microbial Community DNA Standard (Zymo Research, Irvine, CA) was used as a positive control for each targeted library preparation. Negative controls (i.e. blank extraction control, blank library preparation control) were included to assess the level of bioburden carried by the wet-lab process.

Sequencing: The final library was sequenced on Illumina® NextSeq 2000™ with a p1 (Illumina, Sand Diego, CA) reagent kit (600 cycles). The sequencing was performed with 25% PhiX spike-in.

Absolute Abundance Quantification*: A quantitative real-time PCR was set up with a standard curve. The standard curve was made with plasmid DNA containing one copy of the 16S gene and one copy of the fungal ITS2 region prepared in 10-fold serial dilutions. The primers used were the same as those used in Targeted Library Preparation. The equation generated by the plasmid DNA standard curve was used to calculate the number of gene copies in the reaction for each sample. The PCR input volume (2 µl) was used to calculate the number of gene copies per microliter in each DNA sample.
The number of genome copies per microliter DNA sample was calculated by dividing the gene copy number by an assumed number of gene copies per genome. The value used for 16S copies per genome is 4. The value used for ITS copies per genome is 200. The amount of DNA per microliter DNA sample was calculated using an assumed genome size of 4.64 x 106 bp, the genome size of Escherichia coli, for 16S samples, or an assumed genome size of 1.20 x 107 bp, the genome size of Saccharomyces cerevisiae, for ITS samples. This calculation is shown below:

Calculated Total DNA = Calculated Total Genome Copies × Assumed Genome Size (4.64 × 106 bp) ×
Average Molecular Weight of a DNA bp (660 g/mole/bp) ÷ Avogadro’s Number (6.022 x 1023/mole)


* Absolute Abundance Quantification is only available for 16S and ITS analyses.

The absolute abundance standard curve data can be viewed in Excel here:

The absolute abundance standard curve is shown below:

Absolute Abundance Standard Curve

 

IV. Complete Report Download

The complete report of your project, including all links in this report, can be downloaded by clicking the link provided below. The downloaded file is a compressed ZIP file and once unzipped, open the file “REPORT.html” (may only shown as "REPORT" in your computer) by double clicking it. Your default web browser will open it and you will see the exact content of this report.

Please download and save the file to your computer storage device. The download link will expire after 60 days upon your receiving of this report.

Complete report download link:

To view the report, please follow the following steps:

1.Download the .zip file from the report link above.
2.Extract all the contents of the downloaded .zip file to your desktop.
3.Open the extracted folder and find the "REPORT.html" (may shown as only "REPORT").
4.Open (double-clicking) the REPORT.html file. Your default browser will open the top age of the complete report. Within the report, there are links to view all the analyses performed for the project.

 

V. Raw Sequence Data Download

The raw NGS sequence data is available for download with the link provided below. The data is a compressed ZIP file and can be unzipped to individual sequence files. Since this is a Pac-Bio full-length (V1V9) 16S rRNA amplicon sequencing, raw sequences are available for download in a single compressed zip file in the download link below. After unzipping, you will find individual sequence files for each of your samples with the file extension “*.fastq.gz”. The files are in FASTQ format and are compressed. FASTQ format is a text-based data format for storing both a biological sequence and its corresponding quality scores. Most sequence analysis software will be able to open them. The Sample IDs associated with the fastq files are listed in the table below:



Sample IDOriginal Sample IDRead 1 File NameRead 2 File Name


F28914.S100original sample ID herezr28914_100V1V3_R1.fastq.gzzr28914_100V1V3_R2.fastq.gz


F28914.S101original sample ID herezr28914_101V1V3_R1.fastq.gzzr28914_101V1V3_R2.fastq.gz


F28914.S102original sample ID herezr28914_102V1V3_R1.fastq.gzzr28914_102V1V3_R2.fastq.gz


F28914.S103original sample ID herezr28914_103V1V3_R1.fastq.gzzr28914_103V1V3_R2.fastq.gz


F28914.S104original sample ID herezr28914_104V1V3_R1.fastq.gzzr28914_104V1V3_R2.fastq.gz


F28914.S105original sample ID herezr28914_105V1V3_R1.fastq.gzzr28914_105V1V3_R2.fastq.gz


F28914.S106original sample ID herezr28914_106V1V3_R1.fastq.gzzr28914_106V1V3_R2.fastq.gz


F28914.S107original sample ID herezr28914_107V1V3_R1.fastq.gzzr28914_107V1V3_R2.fastq.gz


F28914.S108original sample ID herezr28914_108V1V3_R1.fastq.gzzr28914_108V1V3_R2.fastq.gz


F28914.S109original sample ID herezr28914_109V1V3_R1.fastq.gzzr28914_109V1V3_R2.fastq.gz


F28914.S010original sample ID herezr28914_10V1V3_R1.fastq.gzzr28914_10V1V3_R2.fastq.gz


F28914.S110original sample ID herezr28914_110V1V3_R1.fastq.gzzr28914_110V1V3_R2.fastq.gz


F28914.S111original sample ID herezr28914_111V1V3_R1.fastq.gzzr28914_111V1V3_R2.fastq.gz


F28914.S112original sample ID herezr28914_112V1V3_R1.fastq.gzzr28914_112V1V3_R2.fastq.gz


F28914.S113original sample ID herezr28914_113V1V3_R1.fastq.gzzr28914_113V1V3_R2.fastq.gz


F28914.S114original sample ID herezr28914_114V1V3_R1.fastq.gzzr28914_114V1V3_R2.fastq.gz


F28914.S115original sample ID herezr28914_115V1V3_R1.fastq.gzzr28914_115V1V3_R2.fastq.gz


F28914.S116original sample ID herezr28914_116V1V3_R1.fastq.gzzr28914_116V1V3_R2.fastq.gz


F28914.S117original sample ID herezr28914_117V1V3_R1.fastq.gzzr28914_117V1V3_R2.fastq.gz


F28914.S118original sample ID herezr28914_118V1V3_R1.fastq.gzzr28914_118V1V3_R2.fastq.gz


F28914.S119original sample ID herezr28914_119V1V3_R1.fastq.gzzr28914_119V1V3_R2.fastq.gz


F28914.S011original sample ID herezr28914_11V1V3_R1.fastq.gzzr28914_11V1V3_R2.fastq.gz


F28914.S120original sample ID herezr28914_120V1V3_R1.fastq.gzzr28914_120V1V3_R2.fastq.gz


F28914.S121original sample ID herezr28914_121V1V3_R1.fastq.gzzr28914_121V1V3_R2.fastq.gz


F28914.S122original sample ID herezr28914_122V1V3_R1.fastq.gzzr28914_122V1V3_R2.fastq.gz


F28914.S123original sample ID herezr28914_123V1V3_R1.fastq.gzzr28914_123V1V3_R2.fastq.gz


F28914.S124original sample ID herezr28914_124V1V3_R1.fastq.gzzr28914_124V1V3_R2.fastq.gz


F28914.S125original sample ID herezr28914_125V1V3_R1.fastq.gzzr28914_125V1V3_R2.fastq.gz


F28914.S126original sample ID herezr28914_126V1V3_R1.fastq.gzzr28914_126V1V3_R2.fastq.gz


F28914.S127original sample ID herezr28914_127V1V3_R1.fastq.gzzr28914_127V1V3_R2.fastq.gz


F28914.S128original sample ID herezr28914_128V1V3_R1.fastq.gzzr28914_128V1V3_R2.fastq.gz


F28914.S129original sample ID herezr28914_129V1V3_R1.fastq.gzzr28914_129V1V3_R2.fastq.gz


F28914.S012original sample ID herezr28914_12V1V3_R1.fastq.gzzr28914_12V1V3_R2.fastq.gz


F28914.S130original sample ID herezr28914_130V1V3_R1.fastq.gzzr28914_130V1V3_R2.fastq.gz


F28914.S131original sample ID herezr28914_131V1V3_R1.fastq.gzzr28914_131V1V3_R2.fastq.gz


F28914.S132original sample ID herezr28914_132V1V3_R1.fastq.gzzr28914_132V1V3_R2.fastq.gz


F28914.S133original sample ID herezr28914_133V1V3_R1.fastq.gzzr28914_133V1V3_R2.fastq.gz


F28914.S134original sample ID herezr28914_134V1V3_R1.fastq.gzzr28914_134V1V3_R2.fastq.gz


F28914.S135original sample ID herezr28914_135V1V3_R1.fastq.gzzr28914_135V1V3_R2.fastq.gz


F28914.S136original sample ID herezr28914_136V1V3_R1.fastq.gzzr28914_136V1V3_R2.fastq.gz


F28914.S137original sample ID herezr28914_137V1V3_R1.fastq.gzzr28914_137V1V3_R2.fastq.gz


F28914.S138original sample ID herezr28914_138V1V3_R1.fastq.gzzr28914_138V1V3_R2.fastq.gz


F28914.S139original sample ID herezr28914_139V1V3_R1.fastq.gzzr28914_139V1V3_R2.fastq.gz


F28914.S013original sample ID herezr28914_13V1V3_R1.fastq.gzzr28914_13V1V3_R2.fastq.gz


F28914.S140original sample ID herezr28914_140V1V3_R1.fastq.gzzr28914_140V1V3_R2.fastq.gz


F28914.S141original sample ID herezr28914_141V1V3_R1.fastq.gzzr28914_141V1V3_R2.fastq.gz


F28914.S142original sample ID herezr28914_142V1V3_R1.fastq.gzzr28914_142V1V3_R2.fastq.gz


F28914.S143original sample ID herezr28914_143V1V3_R1.fastq.gzzr28914_143V1V3_R2.fastq.gz


F28914.S144original sample ID herezr28914_144V1V3_R1.fastq.gzzr28914_144V1V3_R2.fastq.gz


F28914.S145original sample ID herezr28914_145V1V3_R1.fastq.gzzr28914_145V1V3_R2.fastq.gz


F28914.S146original sample ID herezr28914_146V1V3_R1.fastq.gzzr28914_146V1V3_R2.fastq.gz


F28914.S147original sample ID herezr28914_147V1V3_R1.fastq.gzzr28914_147V1V3_R2.fastq.gz


F28914.S148original sample ID herezr28914_148V1V3_R1.fastq.gzzr28914_148V1V3_R2.fastq.gz


F28914.S149original sample ID herezr28914_149V1V3_R1.fastq.gzzr28914_149V1V3_R2.fastq.gz


F28914.S014original sample ID herezr28914_14V1V3_R1.fastq.gzzr28914_14V1V3_R2.fastq.gz


F28914.S150original sample ID herezr28914_150V1V3_R1.fastq.gzzr28914_150V1V3_R2.fastq.gz


F28914.S151original sample ID herezr28914_151V1V3_R1.fastq.gzzr28914_151V1V3_R2.fastq.gz


F28914.S152original sample ID herezr28914_152V1V3_R1.fastq.gzzr28914_152V1V3_R2.fastq.gz


F28914.S153original sample ID herezr28914_153V1V3_R1.fastq.gzzr28914_153V1V3_R2.fastq.gz


F28914.S154original sample ID herezr28914_154V1V3_R1.fastq.gzzr28914_154V1V3_R2.fastq.gz


F28914.S155original sample ID herezr28914_155V1V3_R1.fastq.gzzr28914_155V1V3_R2.fastq.gz


F28914.S156original sample ID herezr28914_156V1V3_R1.fastq.gzzr28914_156V1V3_R2.fastq.gz


F28914.S157original sample ID herezr28914_157V1V3_R1.fastq.gzzr28914_157V1V3_R2.fastq.gz


F28914.S158original sample ID herezr28914_158V1V3_R1.fastq.gzzr28914_158V1V3_R2.fastq.gz


F28914.S159original sample ID herezr28914_159V1V3_R1.fastq.gzzr28914_159V1V3_R2.fastq.gz


F28914.S015original sample ID herezr28914_15V1V3_R1.fastq.gzzr28914_15V1V3_R2.fastq.gz


F28914.S160original sample ID herezr28914_160V1V3_R1.fastq.gzzr28914_160V1V3_R2.fastq.gz


F28914.S161original sample ID herezr28914_161V1V3_R1.fastq.gzzr28914_161V1V3_R2.fastq.gz


F28914.S162original sample ID herezr28914_162V1V3_R1.fastq.gzzr28914_162V1V3_R2.fastq.gz


F28914.S163original sample ID herezr28914_163V1V3_R1.fastq.gzzr28914_163V1V3_R2.fastq.gz


F28914.S164original sample ID herezr28914_164V1V3_R1.fastq.gzzr28914_164V1V3_R2.fastq.gz


F28914.S165original sample ID herezr28914_165V1V3_R1.fastq.gzzr28914_165V1V3_R2.fastq.gz


F28914.S166original sample ID herezr28914_166V1V3_R1.fastq.gzzr28914_166V1V3_R2.fastq.gz


F28914.S167original sample ID herezr28914_167V1V3_R1.fastq.gzzr28914_167V1V3_R2.fastq.gz


F28914.S168original sample ID herezr28914_168V1V3_R1.fastq.gzzr28914_168V1V3_R2.fastq.gz


F28914.S169original sample ID herezr28914_169V1V3_R1.fastq.gzzr28914_169V1V3_R2.fastq.gz


F28914.S016original sample ID herezr28914_16V1V3_R1.fastq.gzzr28914_16V1V3_R2.fastq.gz


F28914.S170original sample ID herezr28914_170V1V3_R1.fastq.gzzr28914_170V1V3_R2.fastq.gz


F28914.S171original sample ID herezr28914_171V1V3_R1.fastq.gzzr28914_171V1V3_R2.fastq.gz


F28914.S172original sample ID herezr28914_172V1V3_R1.fastq.gzzr28914_172V1V3_R2.fastq.gz


F28914.S173original sample ID herezr28914_173V1V3_R1.fastq.gzzr28914_173V1V3_R2.fastq.gz


F28914.S174original sample ID herezr28914_174V1V3_R1.fastq.gzzr28914_174V1V3_R2.fastq.gz


F28914.S175original sample ID herezr28914_175V1V3_R1.fastq.gzzr28914_175V1V3_R2.fastq.gz


F28914.S176original sample ID herezr28914_176V1V3_R1.fastq.gzzr28914_176V1V3_R2.fastq.gz


F28914.S177original sample ID herezr28914_177V1V3_R1.fastq.gzzr28914_177V1V3_R2.fastq.gz


F28914.S178original sample ID herezr28914_178V1V3_R1.fastq.gzzr28914_178V1V3_R2.fastq.gz


F28914.S179original sample ID herezr28914_179V1V3_R1.fastq.gzzr28914_179V1V3_R2.fastq.gz


F28914.S017original sample ID herezr28914_17V1V3_R1.fastq.gzzr28914_17V1V3_R2.fastq.gz


F28914.S180original sample ID herezr28914_180V1V3_R1.fastq.gzzr28914_180V1V3_R2.fastq.gz


F28914.S181original sample ID herezr28914_181V1V3_R1.fastq.gzzr28914_181V1V3_R2.fastq.gz


F28914.S182original sample ID herezr28914_182V1V3_R1.fastq.gzzr28914_182V1V3_R2.fastq.gz


F28914.S183original sample ID herezr28914_183V1V3_R1.fastq.gzzr28914_183V1V3_R2.fastq.gz


F28914.S184original sample ID herezr28914_184V1V3_R1.fastq.gzzr28914_184V1V3_R2.fastq.gz


F28914.S185original sample ID herezr28914_185V1V3_R1.fastq.gzzr28914_185V1V3_R2.fastq.gz


F28914.S186original sample ID herezr28914_186V1V3_R1.fastq.gzzr28914_186V1V3_R2.fastq.gz


F28914.S187original sample ID herezr28914_187V1V3_R1.fastq.gzzr28914_187V1V3_R2.fastq.gz


F28914.S188original sample ID herezr28914_188V1V3_R1.fastq.gzzr28914_188V1V3_R2.fastq.gz


F28914.S189original sample ID herezr28914_189V1V3_R1.fastq.gzzr28914_189V1V3_R2.fastq.gz


F28914.S018original sample ID herezr28914_18V1V3_R1.fastq.gzzr28914_18V1V3_R2.fastq.gz


F28914.S190original sample ID herezr28914_190V1V3_R1.fastq.gzzr28914_190V1V3_R2.fastq.gz


F28914.S191original sample ID herezr28914_191V1V3_R1.fastq.gzzr28914_191V1V3_R2.fastq.gz


F28914.S192original sample ID herezr28914_192V1V3_R1.fastq.gzzr28914_192V1V3_R2.fastq.gz


F28914.S193original sample ID herezr28914_193V1V3_R1.fastq.gzzr28914_193V1V3_R2.fastq.gz


F28914.S194original sample ID herezr28914_194V1V3_R1.fastq.gzzr28914_194V1V3_R2.fastq.gz


F28914.S195original sample ID herezr28914_195V1V3_R1.fastq.gzzr28914_195V1V3_R2.fastq.gz


F28914.S196original sample ID herezr28914_196V1V3_R1.fastq.gzzr28914_196V1V3_R2.fastq.gz


F28914.S197original sample ID herezr28914_197V1V3_R1.fastq.gzzr28914_197V1V3_R2.fastq.gz


F28914.S198original sample ID herezr28914_198V1V3_R1.fastq.gzzr28914_198V1V3_R2.fastq.gz


F28914.S199original sample ID herezr28914_199V1V3_R1.fastq.gzzr28914_199V1V3_R2.fastq.gz


F28914.S019original sample ID herezr28914_19V1V3_R1.fastq.gzzr28914_19V1V3_R2.fastq.gz


F28914.S001original sample ID herezr28914_1V1V3_R1.fastq.gzzr28914_1V1V3_R2.fastq.gz


F28914.S200original sample ID herezr28914_200V1V3_R1.fastq.gzzr28914_200V1V3_R2.fastq.gz


F28914.S201original sample ID herezr28914_201V1V3_R1.fastq.gzzr28914_201V1V3_R2.fastq.gz


F28914.S202original sample ID herezr28914_202V1V3_R1.fastq.gzzr28914_202V1V3_R2.fastq.gz


F28914.S203original sample ID herezr28914_203V1V3_R1.fastq.gzzr28914_203V1V3_R2.fastq.gz


F28914.S204original sample ID herezr28914_204V1V3_R1.fastq.gzzr28914_204V1V3_R2.fastq.gz


F28914.S205original sample ID herezr28914_205V1V3_R1.fastq.gzzr28914_205V1V3_R2.fastq.gz


F28914.S206original sample ID herezr28914_206V1V3_R1.fastq.gzzr28914_206V1V3_R2.fastq.gz


F28914.S207original sample ID herezr28914_207V1V3_R1.fastq.gzzr28914_207V1V3_R2.fastq.gz


F28914.S208original sample ID herezr28914_208V1V3_R1.fastq.gzzr28914_208V1V3_R2.fastq.gz


F28914.S209original sample ID herezr28914_209V1V3_R1.fastq.gzzr28914_209V1V3_R2.fastq.gz


F28914.S020original sample ID herezr28914_20V1V3_R1.fastq.gzzr28914_20V1V3_R2.fastq.gz


F28914.S210original sample ID herezr28914_210V1V3_R1.fastq.gzzr28914_210V1V3_R2.fastq.gz


F28914.S211original sample ID herezr28914_211V1V3_R1.fastq.gzzr28914_211V1V3_R2.fastq.gz


F28914.S212original sample ID herezr28914_212V1V3_R1.fastq.gzzr28914_212V1V3_R2.fastq.gz


F28914.S213original sample ID herezr28914_213V1V3_R1.fastq.gzzr28914_213V1V3_R2.fastq.gz


F28914.S214original sample ID herezr28914_214V1V3_R1.fastq.gzzr28914_214V1V3_R2.fastq.gz


F28914.S215original sample ID herezr28914_215V1V3_R1.fastq.gzzr28914_215V1V3_R2.fastq.gz


F28914.S216original sample ID herezr28914_216V1V3_R1.fastq.gzzr28914_216V1V3_R2.fastq.gz


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F28914.S074original sample ID herezr28914_74V1V3_R1.fastq.gzzr28914_74V1V3_R2.fastq.gz


F28914.S075original sample ID herezr28914_75V1V3_R1.fastq.gzzr28914_75V1V3_R2.fastq.gz


F28914.S076original sample ID herezr28914_76V1V3_R1.fastq.gzzr28914_76V1V3_R2.fastq.gz


F28914.S077original sample ID herezr28914_77V1V3_R1.fastq.gzzr28914_77V1V3_R2.fastq.gz


F28914.S078original sample ID herezr28914_78V1V3_R1.fastq.gzzr28914_78V1V3_R2.fastq.gz


F28914.S079original sample ID herezr28914_79V1V3_R1.fastq.gzzr28914_79V1V3_R2.fastq.gz


F28914.S007original sample ID herezr28914_7V1V3_R1.fastq.gzzr28914_7V1V3_R2.fastq.gz


F28914.S080original sample ID herezr28914_80V1V3_R1.fastq.gzzr28914_80V1V3_R2.fastq.gz


F28914.S081original sample ID herezr28914_81V1V3_R1.fastq.gzzr28914_81V1V3_R2.fastq.gz


F28914.S082original sample ID herezr28914_82V1V3_R1.fastq.gzzr28914_82V1V3_R2.fastq.gz


F28914.S083original sample ID herezr28914_83V1V3_R1.fastq.gzzr28914_83V1V3_R2.fastq.gz


F28914.S084original sample ID herezr28914_84V1V3_R1.fastq.gzzr28914_84V1V3_R2.fastq.gz


F28914.S085original sample ID herezr28914_85V1V3_R1.fastq.gzzr28914_85V1V3_R2.fastq.gz


F28914.S086original sample ID herezr28914_86V1V3_R1.fastq.gzzr28914_86V1V3_R2.fastq.gz


F28914.S087original sample ID herezr28914_87V1V3_R1.fastq.gzzr28914_87V1V3_R2.fastq.gz


F28914.S088original sample ID herezr28914_88V1V3_R1.fastq.gzzr28914_88V1V3_R2.fastq.gz


F28914.S089original sample ID herezr28914_89V1V3_R1.fastq.gzzr28914_89V1V3_R2.fastq.gz


F28914.S008original sample ID herezr28914_8V1V3_R1.fastq.gzzr28914_8V1V3_R2.fastq.gz


F28914.S090original sample ID herezr28914_90V1V3_R1.fastq.gzzr28914_90V1V3_R2.fastq.gz


F28914.S091original sample ID herezr28914_91V1V3_R1.fastq.gzzr28914_91V1V3_R2.fastq.gz


F28914.S092original sample ID herezr28914_92V1V3_R1.fastq.gzzr28914_92V1V3_R2.fastq.gz


F28914.S093original sample ID herezr28914_93V1V3_R1.fastq.gzzr28914_93V1V3_R2.fastq.gz


F28914.S094original sample ID herezr28914_94V1V3_R1.fastq.gzzr28914_94V1V3_R2.fastq.gz


F28914.S095original sample ID herezr28914_95V1V3_R1.fastq.gzzr28914_95V1V3_R2.fastq.gz


F28914.S096original sample ID herezr28914_96V1V3_R1.fastq.gzzr28914_96V1V3_R2.fastq.gz


F28914.S097original sample ID herezr28914_97V1V3_R1.fastq.gzzr28914_97V1V3_R2.fastq.gz


F28914.S098original sample ID herezr28914_98V1V3_R1.fastq.gzzr28914_98V1V3_R2.fastq.gz


F28914.S099original sample ID herezr28914_99V1V3_R1.fastq.gzzr28914_99V1V3_R2.fastq.gz


F28914.S009original sample ID herezr28914_9V1V3_R1.fastq.gzzr28914_9V1V3_R2.fastq.gz

Please download and save the file to your computer storage device. The download link will expire after 60 days upon your receiving of this report.

Raw sequence data download link:

 

VI. Analysis - DADA2 Read Processing

What is DADA2?

DADA2 is a software package that models and corrects Illumina-sequenced amplicon errors [1]. DADA2 infers sample sequences exactly, without coarse-graining into OTUs, and resolves differences of as little as one nucleotide. DADA2 identified more real variants and output fewer spurious sequences than other methods.

DADA2’s advantage is that it uses more of the data. The DADA2 error model incorporates quality information, which is ignored by all other methods after filtering. The DADA2 error model incorporates quantitative abundances, whereas most other methods use abundance ranks if they use abundance at all. The DADA2 error model identifies the differences between sequences, eg. A->C, whereas other methods merely count the mismatches. DADA2 can parameterize its error model from the data itself, rather than relying on previous datasets that may or may not reflect the PCR and sequencing protocols used in your study.

DADA2 Software Package is available as an R package at : https://benjjneb.github.io/dada2/index.html

References

  1. Callahan BJ, McMurdie PJ, Rosen MJ, Han AW, Johnson AJ, Holmes SP. DADA2: High-resolution sample inference from Illumina amplicon data. Nat Methods. 2016 Jul;13(7):581-3. doi: 10.1038/nmeth.3869. Epub 2016 May 23. PMID: 27214047; PMCID: PMC4927377.

Analysis Procedures:

DADA2 pipeline includes several tools for read quality control, including quality filtering, trimming, denoising, pair merging and chimera filtering. Below are the major processing steps of DADA2:

Step 1. Read trimming based on sequence quality The quality of NGS Illumina sequences often decreases toward the end of the reads. DADA2 allows to trim off the poor quality read ends in order to improve the error model building and pair mergicing performance.

Step 2. Learn the Error Rates The DADA2 algorithm makes use of a parametric error model (err) and every amplicon dataset has a different set of error rates. The learnErrors method learns this error model from the data, by alternating estimation of the error rates and inference of sample composition until they converge on a jointly consistent solution. As in many machine-learning problems, the algorithm must begin with an initial guess, for which the maximum possible error rates in this data are used (the error rates if only the most abundant sequence is correct and all the rest are errors).

Step 3. Infer amplicon sequence variants (ASVs) based on the error model built in previous step. This step is also called sequence "denoising". The outcome of this step is a list of ASVs that are the equivalent of oligonucleotides.

Step 4. Merge paired reads. If the sequencing products are read pairs, DADA2 will merge the R1 and R2 ASVs into single sequences. Merging is performed by aligning the denoised forward reads with the reverse-complement of the corresponding denoised reverse reads, and then constructing the merged “contig” sequences. By default, merged sequences are only output if the forward and reverse reads overlap by at least 12 bases, and are identical to each other in the overlap region (but these conditions can be changed via function arguments).

Step 5. Remove chimera. The core dada method corrects substitution and indel errors, but chimeras remain. Fortunately, the accuracy of sequence variants after denoising makes identifying chimeric ASVs simpler than when dealing with fuzzy OTUs. Chimeric sequences are identified if they can be exactly reconstructed by combining a left-segment and a right-segment from two more abundant “parent” sequences. The frequency of chimeric sequences varies substantially from dataset to dataset, and depends on on factors including experimental procedures and sample complexity.

Results

1. Read Quality Plots NGS sequence analaysis starts with visualizing the quality of the sequencing. Below are the quality plots of the first sample for the R1 and R2 reads separately. In gray-scale is a heat map of the frequency of each quality score at each base position. The mean quality score at each position is shown by the green line, and the quartiles of the quality score distribution by the orange lines. The forward reads are usually of better quality. It is a common practice to trim the last few nucleotides to avoid less well-controlled errors that can arise there. The trimming affects the downstream steps including error model building, merging and chimera calling. FOMC uses an empirical approach to test many combinations of different trim length in order to achieve best final amplicon sequence variants (ASVs), see the next section “Optimal trim length for ASVs”.

Quality plots for all samples:

2. Optimal trim length for ASVs The final number of merged and chimera-filtered ASVs depends on the quality filtering (hence trimming) in the very beginning of the DADA2 pipeline. In order to achieve highest number of ASVs, an empirical approach was used -

  1. Create a random subset of each sample consisting of 5,000 R1 and 5,000 R2 (to reduce computation time)
  2. Trim 10 bases at a time from the ends of both R1 and R2 up to 50 bases
  3. For each combination of trimmed length (e.g., 300x300, 300x290, 290x290 etc), the trimmed reads are subject to the entire DADA2 pipeline for chimera-filtered merged ASVs
  4. The combination with highest percentage of the input reads becoming final ASVs is selected for the complete set of data

Below is the result of such operation, showing ASV percentages of total reads for all trimming combinations (1st Column = R1 lengths in bases; 1st Row = R2 lengths in bases):

R1/R2301291281271261251
30180.38%81.81%81.75%81.95%82.16%70.85%
29180.43%81.88%81.75%82.01%70.55%57.91%
28180.61%81.99%81.92%70.29%57.79%4.52%
27180.78%82.28%70.46%57.73%4.51%3.47%
26180.88%70.62%57.81%4.55%3.46%2.56%
25169.57%58.27%4.57%3.48%2.56%1.79%

Based on the above result, the trim length combination of R1 = 271 bases and R2 = 291 bases (highlighted red above), was chosen for generating final ASVs for all sequences. This combination generated highest number of merged non-chimeric ASVs and was used for downstream analyses, if requested.

3. Error plots from learning the error rates After DADA2 building the error model for the set of data, it is always worthwhile, as a sanity check if nothing else, to visualize the estimated error rates. The error rates for each possible transition (A→C, A→G, …) are shown below. Points are the observed error rates for each consensus quality score. The black line shows the estimated error rates after convergence of the machine-learning algorithm. The red line shows the error rates expected under the nominal definition of the Q-score. The ideal result would be the estimated error rates (black line) are a good fit to the observed rates (points), and the error rates drop with increased quality as expected.

Forward Read R1 Error Plot


Reverse Read R2 Error Plot

The PDF version of these plots are available here:

 

4. DADA2 Result Summary The table below shows the summary of the DADA2 analysis, tracking paired read counts of each samples for all the steps during DADA2 denoising process - including end-trimming (filtered), denoising (denoisedF, denoisedF), pair merging (merged) and chimera removal (nonchim).

Sample IDF28914.S001F28914.S002F28914.S003F28914.S004F28914.S005F28914.S006F28914.S007F28914.S008F28914.S009F28914.S010F28914.S011F28914.S012F28914.S013F28914.S014F28914.S015F28914.S016F28914.S017F28914.S018F28914.S019F28914.S020F28914.S021F28914.S022F28914.S023F28914.S024F28914.S025F28914.S026F28914.S027F28914.S028F28914.S029F28914.S030F28914.S031F28914.S032F28914.S033F28914.S034F28914.S035F28914.S036F28914.S037F28914.S038F28914.S039F28914.S040F28914.S041F28914.S042F28914.S043F28914.S044F28914.S045F28914.S046F28914.S047F28914.S048F28914.S049F28914.S050F28914.S051F28914.S052F28914.S053F28914.S054F28914.S055F28914.S056F28914.S057F28914.S058F28914.S059F28914.S060F28914.S061F28914.S062F28914.S063F28914.S064F28914.S065F28914.S066F28914.S067F28914.S068F28914.S069F28914.S070F28914.S071F28914.S072F28914.S073F28914.S074F28914.S075F28914.S076F28914.S077F28914.S078F28914.S079F28914.S080F28914.S081F28914.S082F28914.S083F28914.S084F28914.S085F28914.S086F28914.S087F28914.S088F28914.S089F28914.S090F28914.S091F28914.S092F28914.S093F28914.S094F28914.S095F28914.S096F28914.S097F28914.S098F28914.S099F28914.S100F28914.S101F28914.S102F28914.S103F28914.S104F28914.S105F28914.S106F28914.S107F28914.S108F28914.S109F28914.S110F28914.S111F28914.S112F28914.S113F28914.S114F28914.S115F28914.S116F28914.S117F28914.S118F28914.S119F28914.S120F28914.S121F28914.S122F28914.S123F28914.S124F28914.S125F28914.S126F28914.S127F28914.S128F28914.S129F28914.S130F28914.S131F28914.S132F28914.S133F28914.S134F28914.S135F28914.S136F28914.S137F28914.S138F28914.S139F28914.S140F28914.S141F28914.S142F28914.S143F28914.S144F28914.S145F28914.S146F28914.S147F28914.S148F28914.S149F28914.S150F28914.S151F28914.S152F28914.S153F28914.S154F28914.S155F28914.S156F28914.S157F28914.S158F28914.S159F28914.S160F28914.S161F28914.S162F28914.S163F28914.S164F28914.S165F28914.S166F28914.S167F28914.S168F28914.S169F28914.S170F28914.S171F28914.S172F28914.S173F28914.S174F28914.S175F28914.S176F28914.S177F28914.S178F28914.S179F28914.S180F28914.S181F28914.S182F28914.S183F28914.S184F28914.S185F28914.S186F28914.S187F28914.S188F28914.S189F28914.S190F28914.S191F28914.S192F28914.S193F28914.S194F28914.S195F28914.S196F28914.S197F28914.S198F28914.S199F28914.S200F28914.S201F28914.S202F28914.S203F28914.S204F28914.S205F28914.S206F28914.S207F28914.S208F28914.S209F28914.S210F28914.S211F28914.S212F28914.S213F28914.S214F28914.S215F28914.S216F28914.S217F28914.S218F28914.S219F28914.S220F28914.S221F28914.S222F28914.S223F28914.S224F28914.S225F28914.S226F28914.S227F28914.S228F28914.S229F28914.S230F28914.S231F28914.S232F28914.S233F28914.S234F28914.S235F28914.S236F28914.S237F28914.S238F28914.S239F28914.S240F28914.S241F28914.S242F28914.S243F28914.S244F28914.S245F28914.S246F28914.S247F28914.S248F28914.S249F28914.S250F28914.S251F28914.S252F28914.S253F28914.S254F28914.S255F28914.S256F28914.S257F28914.S258F28914.S259F28914.S260F28914.S261F28914.S262F28914.S263F28914.S264F28914.S265F28914.S266F28914.S267F28914.S268F28914.S269F28914.S270F28914.S271F28914.S272F28914.S273F28914.S274F28914.S275F28914.S276F28914.S277F28914.S278F28914.S279F28914.S280F28914.S281F28914.S282F28914.S283F28914.S284F28914.S285F28914.S286F28914.S287F28914.S288F28914.S289F28914.S290F28914.S291F28914.S292F28914.S293F28914.S294F28914.S295F28914.S296F28914.S297F28914.S300F28914.S301F28914.S302F28914.S303F28914.S304F28914.S305F28914.S306F28914.S307F28914.S308F28914.S309F28914.S310F28914.S311F28914.S312F28914.S313F28914.S314F28914.S315F28914.S316F28914.S317F28914.S318F28914.S319F28914.S320F28914.S321F28914.S322F28914.S323F28914.S324F28914.S325F28914.S326F28914.S327F28914.S328F28914.S329F28914.S330F28914.S331F28914.S332F28914.S333F28914.S334F28914.S335F28914.S336F28914.S337F28914.S338F28914.S339F28914.S340F28914.S341F28914.S342F28914.S343F28914.S344F28914.S345F28914.S346F28914.S347F28914.S348F28914.S349F28914.S350F28914.S351F28914.S352F28914.S353F28914.S354F28914.S355F28914.S356F28914.S357F28914.S358F28914.S359F28914.S360F28914.S361F28914.S362F28914.S363F28914.S364F28914.S365F28914.S366F28914.S367F28914.S368F28914.S369F28914.S370F28914.S371F28914.S372F28914.S373F28914.S374F28914.S375F28914.S376F28914.S377F28914.S378F28914.S379F28914.S380F28914.S381F28914.S382F28914.S383F28914.S384F28914.S385F28914.S386F28914.S387F28914.S388F28914.S389F28914.S390F28914.S391F28914.S392F28914.S393F28914.S394F28914.S395F28914.S396F28914.S397F28914.S398F28914.S399F28914.S400F28914.S401F28914.S402F28914.S403F28914.S404F28914.S405F28914.S406F28914.S407F28914.S408F28914.S409F28914.S410F28914.S411F28914.S412F28914.S413F28914.S414F28914.S415F28914.S416F28914.S417F28914.S418F28914.S419F28914.S420F28914.S421F28914.S422F28914.S423F28914.S424F28914.S425F28914.S426F28914.S427F28914.S428F28914.S429F28914.S430F28914.S431F28914.S432F28914.S433F28914.S434F28914.S435F28914.S436F28914.S437F28914.S438F28914.S439F28914.S440F28914.S441F28914.S442F28914.S443F28914.S444F28914.S445F28914.S446F28914.S447F28914.S448F28914.S449F28914.S450F28914.S451F28914.S452F28914.S453F28914.S454F28914.S455F28914.S456F28914.S457F28914.S458F28914.S459F28914.S460F28914.S461F28914.S462F28914.S463F28914.S464F28914.S465F28914.S466F28914.S467F28914.S468F28914.S469F28914.S470F28914.S471F28914.S472F28914.S473F28914.S474F28914.S475F28914.S476F28914.S477F28914.S478F28914.S479F28914.S480F28914.S481F28914.S482F28914.S483F28914.S484F28914.S485F28914.S486F28914.S487F28914.S488F28914.S489F28914.S490F28914.S491F28914.S492F28914.S493F28914.S494F28914.S495F28914.S496F28914.S497F28914.S498F28914.S499F28914.S500F28914.S501F28914.S502F28914.S503F28914.S504F28914.S505F28914.S506F28914.S507F28914.S508F28914.S509F28914.S510F28914.S511F28914.S512F28914.S513F28914.S514F28914.S515F28914.S516F28914.S517F28914.S518F28914.S519F28914.S520F28914.S521F28914.S522F28914.S523F28914.S524F28914.S525F28914.S526F28914.S527F28914.S528F28914.S529F28914.S530F28914.S531F28914.S532F28914.S533F28914.S534F28914.S535F28914.S536F28914.S537F28914.S538F28914.S539F28914.S540F28914.S541F28914.S542F28914.S543F28914.S544F28914.S545F28914.S546F28914.S547F28914.S548F28914.S549F28914.S550F28914.S551F28914.S552F28914.S553F28914.S554F28914.S555F28914.S556F28914.S557F28914.S558F28914.S559F28914.S560F28914.S561F28914.S562F28914.S563F28914.S564F28914.S565F28914.S566F28914.S567F28914.S568F28914.S569F28914.S570F28914.S571F28914.S572F28914.S573F28914.S574F28914.S575F28914.S576F28914.S577F28914.S578F28914.S579F28914.S580F28914.S581F28914.S582F28914.S583F28914.S584F28914.S585F28914.S586F28914.S587F28914.S588F28914.S589F28914.S590F28914.S591F28914.S592F28914.S593F28914.S594F28914.S595F28914.S596F28914.S597F28914.S598F28914.S599F28914.S600F28914.S601F28914.S602F28914.S603F28914.S604F28914.S605F28914.S606F28914.S607F28914.S608F28914.S609F28914.S610F28914.S611F28914.S612F28914.S613F28914.S614F28914.S615F28914.S616F28914.S617F28914.S618F28914.S619F28914.S620F28914.S621F28914.S622F28914.S623F28914.S624F28914.S625F28914.S626F28914.S627F28914.S628F28914.S629F28914.S630F28914.S631F28914.S632F28914.S633F28914.S634F28914.S635F28914.S636F28914.S637F28914.S638F28914.S639F28914.S640F28914.S641F28914.S642F28914.S643F28914.S644F28914.S645F28914.S646F28914.S647F28914.S648F28914.S649F28914.S650F28914.S651F28914.S652F28914.S653F28914.S654F28914.S655F28914.S656F28914.S657F28914.S658F28914.S659F28914.S660F28914.S661F28914.S662F28914.S663F28914.S664F28914.S665F28914.S666F28914.S667F28914.S668F28914.S669F28914.S670F28914.S671F28914.S672Row SumPercentage
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filtered58,90692,67485,55047,25762,30266,42075,03374,30666,55673,32781,81169,43761,86747,21770,06962,53562,20256,47965,13669,92868,69074,01959,12669,32754,22287,99472,27372,04485,07366,82368,97270,30569,14567,96772,71572,66574,12265,23979,08965,19486,17766,48278,29086,172101,76488,96659,34263,47584,712103,32280,55967,62174,41791,83971,40770,09465,06880,61064,56762,99074,959122,02979,25078,65269,59056,489114,581119,301116,61387,98964,08965,80672,01566,76788,57765,55964,09962,06466,84550,04080,07893,55474,94484,80267,89985,34477,14283,56175,69075,56661,49382,75268,64871,76167,90074,46362,98864,53371,07277,83074,52864,59881,12477,11275,23173,11177,14983,74976,71275,60876,15972,58554,75565,09371,55868,30972,16180,48977,87466,60157,58274,07062,62455,00269,91071,71274,78363,36053,54661,36665,53377,01575,23966,24277,79667,57772,34866,84866,83964,50875,11383,43273,06366,80458,90468,64172,77864,67772,82675,96865,58368,84465,32369,98481,41767,05090,54684,51575,56371,92768,91074,01583,54184,57788,48780,68089,41266,77668,97980,68558,75885,93185,55269,81077,83367,45383,559102,38470,27490,406101,13892,20272,68988,58264,14766,66775,16967,16173,84373,66150,66278,61655,33961,70982,75663,61155,53771,45959,41857,99067,45394,12736,72269,81168,32564,41189,07887,12768,22780,37675,06494,24676,68765,34967,56186,41381,34168,40373,84689,55567,87160,84972,35170,80185,52576,31872,98383,96573,26171,64885,92176,98572,84065,22480,89870,96565,34673,22576,56463,33173,90485,66165,55087,05276,90668,88684,24176,05855,75086,89383,26946,19459,84570,42477,60867,70763,16350,38968,15669,73261,93660,16462,17564,43467,60370,90654,41577,97956,71574,36870,49376,34177,40264,53355,40577,22161,80263,73163,23066,04371,43459,85666,30158,95375,78660,84866,24473,49189,66078,02253,76360,49171,39993,67587,93567,03075,62572,84860,98676,89162,53657,86874,28499,89168,37468,40288,38270,03396,716105,399134,28673,21056,33380,06984,04466,61493,17172,72372,12662,97970,27763,19389,32496,14575,92989,54370,81288,68284,96296,58577,92078,74963,52395,98779,94656,00472,26356,38881,62476,52470,76083,98581,79275,81180,66285,05272,46466,41385,83881,13083,13873,54177,37978,90874,67072,65478,84277,43177,09679,09973,90684,11373,90184,10581,96881,03365,90979,43467,44862,81565,00369,25078,05774,16167,31679,90475,89274,75784,31968,54277,69076,44071,27568,35078,40479,86270,36468,75374,02370,98863,64073,00567,90768,39362,48562,10266,97561,20387,02779,90774,99568,63270,47558,25282,90482,49578,57273,40182,84267,93267,26780,86754,87393,24177,10864,12058,95768,65572,42587,04768,11382,22886,90177,23780,26977,80472,61080,31866,29283,88249,68153,01256,76752,31154,87052,86345,23370,15971,57857,86378,05163,01458,67663,60256,70357,72857,17682,45132,02164,48376,45167,53659,50469,77164,99755,86059,28854,75560,50473,70876,70753,48765,03377,08764,38652,34363,78266,00675,33469,91364,99759,02779,39967,32561,81964,36167,95857,29158,41956,86474,12859,38582,93647,20162,07849,22437,59856,27434,36849,59750,34739,10845,90741,81560,10548,97957,50944,21941,03752,90485,089102,32063,10460,96978,55561,53457,87164,42850,48358,63443,63444,10574,22258,74157,45759,25852,23663,82846,80241,35762,07365,81365,156102,38388,56654,49375,75595,58971,48179,11479,47580,69876,73676,46674,52860,24376,03891,32071,00075,45963,40075,00379,89581,63571,73286,07257,88296,43976,09885,414107,35984,35578,57088,53472,31876,87579,31069,85383,85978,34875,05169,79192,11275,33683,01888,187107,40096,30866,68775,18495,958120,07996,84384,16395,072121,13884,80289,73784,46091,18977,13074,85988,983129,84287,46883,58291,94166,461120,728112,631100,42290,06366,89977,00094,05778,58596,63686,04094,53484,22660,43370,49990,446123,88388,63791,98682,569102,92385,238104,52679,29180,83566,350101,87090,22983,36879,56988,89782,32677,27476,72579,75785,29167,90496,20786,95180,18483,60889,85692,47088,89687,02976,29293,19974,28885,09894,21789,70478,34071,80489,83988,49473,489129,525102,11175,44883,36384,255105,754102,78478,83683,28682,054100,94381,85475,53990,51179,14681,89684,60378,58171,03885,66084,47376,59470,05277,63181,65885,00776,21149,718,349100.00%
denoisedF57,82891,54484,31146,47761,10565,35773,87773,37465,68172,34780,51568,26161,03846,41368,72961,49161,30555,51164,18569,02567,70072,78958,42268,46253,83287,44771,76671,61384,60166,46668,56269,95968,75267,50572,31972,33873,59564,83278,38664,57785,63865,93777,78285,749101,34488,63359,03962,97184,188102,63479,96167,13973,92591,05871,13269,74664,55280,22864,29562,53274,407121,28178,67678,01969,06055,983114,238118,977116,11387,53463,72665,44671,47466,35587,89065,01263,64161,54266,32549,58079,57692,83174,45184,00967,39884,77076,44382,95175,16075,07061,09582,30368,09071,20767,44973,92262,47763,91470,61477,24973,95264,12680,51076,56274,77372,55876,50282,95476,13075,17075,47772,01254,21464,51271,08067,81971,70480,05477,34866,25356,90673,45062,02454,47869,37271,01174,14362,71853,11260,77265,07776,05374,66565,84277,42067,02271,68466,35966,30063,75874,56982,83172,48366,30058,19168,01172,18464,20872,36275,32865,01968,43065,13069,56081,14466,80390,24684,27375,17271,59168,83373,88183,33684,47788,33180,42889,16566,63868,81680,47958,65385,63885,35969,53677,53967,18883,241101,94470,17390,125100,80691,82572,24588,11464,02066,53274,96766,99773,69373,52450,52778,37955,08761,22082,37363,33655,28271,17859,16857,69767,27393,92136,61769,65868,05664,12188,96186,84367,99179,92074,83194,01976,54665,16367,41986,19581,04968,17473,66189,29567,62060,65072,07670,74985,32676,10772,54883,81373,01471,52485,63976,74672,29964,75980,30970,42264,88972,59675,97162,83073,41885,19364,97186,43576,47168,51783,62875,44455,34786,26682,83045,83959,50369,84477,05967,26962,56649,92267,61069,34561,47759,56561,63164,00267,04370,46454,08877,24756,17273,77770,13375,89176,90664,02855,03876,65861,27663,27462,84065,55470,81459,42365,72558,63575,30760,27865,74972,94489,20977,59753,34860,03970,90793,14687,36866,51475,01472,14260,56876,27462,11157,30073,88599,38267,93267,90987,78869,36796,059104,926133,90272,93756,17679,73083,56066,43292,92772,38871,96562,80670,11463,06789,18095,95275,70389,38470,59488,38084,74596,31377,70278,51063,29995,72279,74255,86572,09656,19781,39276,37570,51483,82881,60575,54380,44884,89572,14366,04885,37180,78282,90673,08277,13578,61874,45772,35378,59477,06776,95378,95073,81083,89873,75883,89481,81880,78365,75679,26867,32162,64464,89869,12277,85973,85567,25379,69775,80374,62584,19068,40177,45476,02371,11868,22778,28779,73470,21368,64573,84470,79063,33072,76167,77868,25762,11361,73366,46560,73886,89679,78674,90768,53670,32358,12382,65782,28278,38373,18682,56967,70067,08380,58454,73092,94676,90463,93758,76468,48572,10586,65367,76881,93786,68576,98179,94177,49972,53280,17366,16183,73549,31652,43456,31451,81254,34552,48144,57569,61571,33057,69377,88562,85358,54663,47056,55957,55456,88782,19831,92464,32876,18667,33259,29569,60464,82955,73859,15054,68160,34873,49876,52253,31764,76776,77264,15852,16763,54465,71175,13069,70064,87158,92779,25667,18061,59163,95167,62057,02058,33856,76273,98959,31282,75647,11161,98149,08437,55356,18134,31449,54550,28839,06245,84341,71959,97448,81557,43444,10740,97152,84284,738102,03562,97160,81378,44261,45357,81264,36950,40158,56543,30243,79873,86458,39657,24158,93951,86963,37546,74741,25062,01365,70465,038102,18888,48054,36575,59895,45671,39379,04679,28980,62576,46576,28074,42960,17275,98791,26170,88475,32363,21474,84679,74681,54271,66585,98757,76696,36675,94385,299106,58983,77778,03388,03071,95376,25078,67469,35383,73078,15274,86769,68091,91175,16482,85287,996107,25495,92566,44174,91495,673119,78496,58283,96394,628120,77484,42989,33683,97690,77177,04474,39088,888129,71687,35683,42491,75666,339120,508112,49199,71689,53066,46376,58193,60778,36696,40285,67894,01783,82260,24670,26890,305123,42788,32191,75782,123102,52284,996104,14378,96280,45666,028101,46989,67182,93179,20488,51782,23377,16976,60979,56285,20867,73196,09286,85780,09883,44589,77192,32788,75586,85176,22993,11974,16484,98394,08389,60578,27071,74789,78088,34972,954129,149101,81575,26883,31784,047105,598102,55678,46582,94681,714100,59781,73375,32690,40878,98481,69184,49078,47370,92285,37384,29476,48569,95777,52481,54384,83876,07149,489,05299.54%
denoisedR57,19590,07683,28345,81260,63464,33673,55872,66064,92571,75880,05167,84960,32645,80768,46161,04860,63854,80163,75468,34367,07872,42757,78267,80853,53286,94171,59271,29184,03566,11068,49169,73368,64267,43272,21972,18473,20164,36278,09564,24885,11365,47877,70385,401100,85988,31458,75562,96183,911102,25479,43666,61073,43590,76670,72969,42864,58679,99764,04262,42173,847120,61078,26977,53068,71655,512113,619118,573115,93687,36963,53765,26671,10466,05687,78264,83763,35061,34966,02549,38979,27292,58574,02083,81667,13084,47476,25782,59175,02374,77260,86781,95667,87671,06367,27373,81262,17463,84470,18776,85973,69263,76080,14276,28774,43872,20776,35082,44375,94274,83775,19571,73454,05564,23870,55367,51771,41579,66577,07165,86956,65072,96261,74254,17068,75470,78073,92662,60652,77760,42864,85676,01374,29865,48477,04866,77071,36966,05066,01863,53574,14382,53872,11065,90558,05667,83071,81763,78571,94175,16964,73868,05264,95469,39080,78266,47289,90784,01974,99571,30468,65573,70983,14184,19788,13380,24589,01766,46368,60180,10658,47385,25185,01769,32677,14567,01182,745101,70969,98589,887100,34191,39271,81888,01563,84866,27974,69966,81073,34873,34750,42278,16654,90361,03582,23763,17455,05870,88658,78757,43967,07393,70936,56269,51767,72663,69088,72486,38767,92279,77574,62693,74776,47965,04967,29985,94380,84567,97573,54389,10667,45760,48471,65570,52985,05575,90372,43183,46472,76871,28085,51776,45772,10164,43880,18370,18664,81672,37575,82662,65873,30384,90164,99086,38576,27168,32083,40975,26255,24686,12982,53945,61059,25169,70176,99567,09662,56949,86167,45869,01761,34859,57961,50663,82566,93470,18353,64677,10256,20373,53369,83975,65076,62963,80054,81076,29061,13862,90962,57865,29270,84059,31365,68758,40875,07360,14665,41672,72088,93077,36353,16659,88670,73192,77487,20966,31775,04372,10660,38076,13361,89457,18073,65598,99067,74767,70587,59569,21995,983104,463133,60672,77655,90379,63383,50766,10392,63172,27871,64162,72869,95362,93088,98595,68875,59388,92870,50988,26184,65295,93377,40678,31863,07995,49879,56955,76671,95256,07381,29576,21370,45083,41781,44375,45480,17584,59872,03866,04285,36280,72582,62073,12876,84078,31374,20972,25778,43976,87076,78878,72173,67983,63473,60283,82381,52280,63765,66479,16467,18962,53164,78668,93177,70673,64067,14079,58975,63574,41684,08868,32577,35076,06370,99368,12878,10179,55070,05468,48973,72670,71463,19972,63567,66868,06662,04261,59266,37160,52286,82079,69474,78168,47670,22158,01982,57882,19478,20373,02182,51467,60766,89480,53754,52992,70376,61163,78858,61468,35571,91386,46667,46081,55686,46476,85979,72677,44572,42580,10466,06383,60649,13552,28256,18751,61954,13152,20344,54769,27671,25057,63677,78362,78358,36463,27756,51657,42656,83682,03231,86264,27376,05667,18959,09869,33164,67255,57659,02854,60060,21573,38276,39953,29664,65376,74064,05252,04363,29065,67774,99469,62664,71458,83179,16667,13261,51563,94767,49156,78958,24656,70773,91859,23182,69447,07961,91349,07737,48456,14134,29949,47950,21639,00545,79741,70159,83748,63657,23243,91340,92952,67084,622101,90862,87760,69678,33761,31757,64563,97950,21658,38043,27243,80873,63558,29356,95458,75951,67463,15046,65041,19861,88065,63364,928101,94488,20554,24875,51695,27271,29878,91379,16380,36376,38276,20674,22460,02275,81091,04570,79875,20363,12474,76179,62581,40871,53385,83157,65696,12975,84285,104106,30883,55577,58187,56971,55576,03378,57569,09683,56278,06274,63269,37991,76474,89482,58387,754106,99895,85966,40574,78095,560119,41096,26883,59794,361120,23384,26489,17783,61490,44376,76274,26288,729129,45887,00783,32191,61866,222120,334112,27699,53489,04066,10676,20593,65378,23196,21985,52794,10583,78160,02170,01390,090123,09188,06791,56781,982102,18084,749103,87778,77080,36865,894101,27889,72582,74379,03988,33982,06276,86076,40979,44284,98567,73995,87486,65379,81683,34289,52992,12188,53286,74375,93592,81473,91584,84693,94789,36178,11271,59689,57488,12372,879128,781101,48475,04183,12283,754105,284102,15278,21582,67181,475100,26381,52675,20990,20478,67481,55684,19378,32870,83685,13384,12376,25069,82577,31681,20284,64175,89149,341,55499.24%
merged53,10784,09578,10242,31256,35060,02669,36268,79260,98967,56675,26463,76156,47242,78563,89856,92056,83150,61360,15764,40262,79468,01254,09763,68350,74382,87368,33168,10980,21963,25065,51167,06265,65365,11169,66869,63370,18161,79874,65061,42981,81362,57675,09282,58297,81785,48956,75860,54580,42998,18276,11163,75269,98386,81368,74967,00762,49777,75762,14460,52971,071116,37975,12474,33465,83853,182110,223115,405112,65684,73961,46463,12567,91862,94783,86161,88360,07958,56663,03347,04975,32688,07470,02179,82663,93381,06672,87478,88571,91571,76458,18778,81765,17068,02164,61170,75059,32260,94067,07673,30470,23861,16876,81473,07871,11169,06872,99978,88472,75371,85271,89368,53551,45460,82267,21364,56768,52776,14673,72763,15353,65969,28158,44651,35765,47667,04070,50859,60350,20357,45362,08372,30570,82362,87774,40263,94167,69163,01162,77360,16570,63678,78868,94562,95255,04364,77168,19960,81769,02771,98161,71865,31662,42366,29877,54864,27386,24880,79972,46168,36467,33071,69281,13982,98786,13978,50987,32364,95066,73877,93356,83682,98182,95367,27074,90264,69179,58198,38768,96187,32097,48487,52169,24685,46062,17664,36373,17265,46371,90872,07649,39376,38552,76358,21278,84461,01052,74668,47256,32855,33765,51487,25435,51667,80765,82861,29787,16883,74766,27776,77472,53290,76174,96463,58465,55183,44278,59966,08771,73086,61365,48258,89769,74069,44182,62873,22470,08281,46570,34169,68683,88874,70569,05561,52676,76066,97862,09068,97872,59159,74470,62482,00962,37182,91573,70865,50679,96772,31052,84782,72579,42543,39056,86266,61573,80064,37159,99147,68164,52466,18458,96557,22758,74261,21964,05067,36951,32573,66153,47570,55367,02372,63073,61860,90852,34773,12258,32260,23259,83362,21767,82156,43262,56455,87071,41357,31062,28669,21485,95174,64450,98257,64267,90389,38683,83663,60571,56868,73157,61872,56658,99654,36170,91995,46965,10565,07284,20665,93092,114100,841129,64570,18754,01476,94880,72363,92490,05969,71169,93961,51768,38561,46087,22493,16773,74787,02268,62986,10982,80092,99775,41576,13761,47693,20577,17354,48370,29554,80279,34974,73968,74681,26779,84873,70878,08883,04169,66164,42982,77178,71180,05670,40174,52076,08671,71970,01975,63573,58275,26676,94371,89981,73771,84181,75279,41978,38164,53977,58565,69760,69363,09767,38275,19770,70966,03577,88474,27172,74982,26866,80875,00873,46569,22366,46576,41378,03268,11766,94471,42968,95661,11170,07965,40866,34059,46859,24763,25957,87085,22978,21373,33667,25268,72756,86580,41179,93176,10571,20980,11565,78265,05678,35253,07490,05974,64562,25456,96466,56269,76183,95765,44779,02584,37374,65577,45874,96471,33878,75464,88982,27046,91749,62353,50748,96451,35349,82241,98166,03269,11855,98775,86661,21856,01659,86254,17853,67855,21679,62631,03362,73673,38863,89956,45464,61562,89054,07557,74753,51958,03069,62073,62050,23162,77774,77462,44150,51560,13061,29672,23964,95963,21057,56877,46365,63259,65561,85764,74554,78657,14355,74472,64158,18580,99146,10960,65048,03836,78055,11633,66548,60649,19138,32045,03040,85258,41647,20456,13042,83040,22551,56882,59099,71761,28559,00276,87860,19056,63962,77149,41357,07841,27041,98070,77055,72554,55556,45949,37960,24145,65140,25360,64064,34963,13697,74885,04950,95674,41093,48470,03277,69177,15776,48073,18071,75672,76858,83874,46489,52769,02472,08061,29670,66878,11079,89970,53784,17055,21390,51673,75579,912102,03179,95374,41684,05868,73973,04475,50366,24081,59475,90472,28267,21789,24673,03280,81385,409104,45193,09364,43472,68892,955116,32593,83681,44891,248116,84281,73886,54181,13587,83275,71071,75287,323127,20585,26881,55589,67564,723118,226110,42995,67685,50763,35673,16590,98576,09193,84882,50591,55581,46958,57267,67388,129119,20885,19788,92079,03398,18882,089100,56576,50278,07063,46497,98186,87180,14376,44985,64580,19375,24474,74777,71182,79966,00794,42984,94678,00081,57587,61090,30786,21184,58674,54891,05372,35683,11491,85887,68276,72870,45988,35186,32070,142125,13799,37572,21281,92281,319103,30599,66274,75580,03078,97497,41079,47273,60788,04876,66179,80982,31276,52969,21383,48281,94174,42268,21475,67078,92282,69973,97647,683,44895.91%
nonchim47,96574,07370,33638,65051,10353,55761,68861,77654,47758,78366,92157,14751,29939,54657,28051,45451,38645,35253,70257,31654,06160,43147,44554,35539,60764,88655,42953,14062,74151,25453,56853,90453,32151,69655,20056,05159,54751,97460,92252,38568,43651,64362,45766,87682,27972,20547,64548,26064,55479,53661,43651,97856,69967,95752,13453,73347,91259,04646,91546,08860,00299,62164,23361,52755,37643,76489,10195,11694,43071,41749,38551,19353,40949,16268,74648,78347,47746,34550,32837,91562,71274,04358,24165,65054,57168,01960,89463,73158,78759,00947,22161,09450,43555,39452,72856,65248,96949,72255,99659,39658,16150,85763,21158,48661,00155,73661,70164,05758,45258,89356,97356,65540,51148,68754,07452,09854,71860,53358,61551,10544,20856,75849,61942,02752,78253,00456,96850,31041,11245,71950,74457,60056,04650,40460,37551,97456,96652,57151,63650,11756,00063,45357,43651,37843,64453,77856,71047,07154,37256,13647,89952,38950,87053,20561,00752,21766,25062,38158,59654,40161,35660,53868,81372,27175,18867,40174,75155,89361,55067,51851,80367,38771,01361,53563,51655,68771,35683,88955,60980,33488,13473,59561,60476,59354,56149,86858,95554,57461,39161,59142,55060,97741,39546,00063,09548,25341,32255,27543,43242,91256,56877,05830,61158,99059,51356,10079,50977,29958,47767,01765,60782,26868,91955,29657,79476,18565,84459,06662,43678,29955,32552,65458,45863,70775,16965,14462,18574,23161,07656,62868,05670,55956,26849,79961,73154,32949,18453,87657,72546,62658,81368,05353,13369,78559,95152,63162,24757,08441,51564,96662,77336,00743,97652,62760,05352,59949,22638,20751,50652,86946,48646,69247,70750,14252,01956,76643,05258,52842,56258,06952,90257,35957,00549,10442,41259,23245,25848,63248,78748,40554,63045,92251,21845,71259,39647,01649,27553,58070,21858,56742,37047,05754,09471,80568,07251,77459,66054,07948,13058,87149,03642,35156,00580,29851,95854,49867,25554,00376,70485,230102,62655,26843,37160,76063,99249,67973,43055,71059,21753,34556,97352,06175,27080,12362,08068,63760,35272,89769,76979,10861,71163,38150,60770,24565,96246,69859,39046,24268,12662,53656,51068,33268,54461,36964,07573,10555,68852,72565,09564,47463,77455,36060,90261,32157,79156,60062,31458,75169,32567,92358,94971,94554,06765,53662,85161,68460,08470,54054,55451,04754,04456,94665,08461,90651,70966,24269,19262,46569,70256,93762,21360,46754,34456,52163,49269,42258,54057,46259,49362,40247,28859,99552,75658,21649,43548,00749,57845,71777,82671,30666,90261,57659,15650,91366,76566,63869,73265,27672,67360,50054,29672,08048,95879,62666,54055,53550,47859,41261,07173,94954,73468,21276,32268,40870,26468,13470,76677,70664,22881,00837,89939,67242,99339,70041,75739,69133,95153,92156,57844,71858,50953,88147,05945,61344,07041,13450,51568,28727,61456,70762,59253,36745,85550,49351,20842,03348,06148,17749,44952,73662,47938,17751,67960,21056,11139,81150,03548,72956,81751,20051,76952,92570,47860,49852,87749,19749,98144,58151,46650,48465,19852,80566,94040,41047,75636,94733,49250,35330,68144,26037,42535,28241,06035,55049,93739,77552,23740,10937,40946,99068,35390,83858,61550,63770,84855,15952,80860,71245,77054,48034,19434,78555,64746,16445,89245,02841,31450,59735,03631,11645,11154,44252,15576,07869,46439,51570,86379,43463,60470,93267,35761,58659,60457,54360,01947,85762,94182,75960,72057,93851,33756,67566,70666,38465,88967,61146,32970,85960,06764,31387,88068,58263,59572,86957,83661,49862,93655,98667,66263,19958,65157,38076,19464,06174,30277,52890,88777,68755,54363,09480,104104,85483,17475,75279,553100,34770,36670,77768,52774,21475,30462,13985,874123,98282,62278,29786,61262,036114,855107,96381,32468,60850,71760,08784,68762,79383,16672,40784,85971,87651,85660,13379,023109,98575,23877,83670,96088,78073,96889,70065,87366,44153,65484,44571,28065,94463,22471,84166,49059,30558,00260,80766,63753,99285,04274,68466,28964,96372,68771,72868,31171,24564,53879,36557,61073,31781,05369,99667,54961,04988,35177,10657,094117,14393,67267,16778,34574,882100,97095,34461,90364,86266,19382,18769,78759,28473,49163,56363,44864,52264,91558,43869,61470,35962,01358,52461,13668,19070,63063,35640,264,14980.98%

This table can be downloaded as an Excel table below:

 

5. DADA2 Amplicon Sequence Variants (ASVs). A total of 9960 unique merged and chimera-free ASV sequences were identified, and their corresponding read counts for each sample are available in the "ASV Read Count Table" with rows for the ASV sequences and columns for sample. This read count table can be used for microbial profile comparison among different samples and the sequences provided in the table can be used to taxonomy assignment.

 

The table can be downloaded from this link:

 
 

Sample Meta Information

Download Sample Meta Information
#SampleIDSample Name#SampleIDGroup001Group002Group003Group005Group006Group007Group009Group010
F28914.S001Day1.Rep1.SalivaS001SALIVA Pool 1 PMA-SST Saliva P1 PMA-SST Saliva PMA-NASMT Saliva P1 PMA-SMT Saliva PMA-NANA
F28914.S002Day1.Rep2.SalivaS002SALIVA Pool 1 PMA-SST Saliva P1 PMA-SST Saliva PMA-NASMT Saliva P1 PMA-SMT Saliva PMA-NANA
F28914.S003Day1.Rep3.SalivaS003SALIVA Pool 1 PMA-SST Saliva P1 PMA-SST Saliva PMA-NASMT Saliva P1 PMA-SMT Saliva PMA-NANA
F28914.S004Day1.Rep4.SalivaS004SALIVA Pool 1 PMA-SST Saliva P1 PMA-SST Saliva PMA-NASMT Saliva P1 PMA-SMT Saliva PMA-NANA
F28914.S005Day1.Rep5.SalivaS005SALIVA Pool 1 PMA-SST Saliva P1 PMA-SST Saliva PMA-NASMT Saliva P1 PMA-SMT Saliva PMA-NANA
F28914.S006Day1.Rep6.SalivaS006SALIVA Pool 1 PMA-SST Saliva P1 PMA-SST Saliva PMA-NASMT Saliva P1 PMA-SMT Saliva PMA-NANA
F28914.S007Day1.V.Rep1.SalivaS007SALIVA Pool 1 PMA+SST Saliva P1 PMA+SST Saliva PMA+NASMT Saliva P1 PMA+SMT Saliva PMA+NANA
F28914.S008Day1.V.Rep2.SalivaS008SALIVA Pool 1 PMA+SST Saliva P1 PMA+SST Saliva PMA+NASMT Saliva P1 PMA+SMT Saliva PMA+NANA
F28914.S009Day1.V.Rep3.SalivaS009SALIVA Pool 1 PMA+SST Saliva P1 PMA+SST Saliva PMA+NASMT Saliva P1 PMA+SMT Saliva PMA+NANA
F28914.S010Day1.V.Rep4.SalivaS010SALIVA Pool 1 PMA+SST Saliva P1 PMA+SST Saliva PMA+NASMT Saliva P1 PMA+SMT Saliva PMA+NANA
F28914.S011Day1.V.Rep5.SalivaS011SALIVA Pool 1 PMA+SST Saliva P1 PMA+SST Saliva PMA+NASMT Saliva P1 PMA+SMT Saliva PMA+NANA
F28914.S012Day1.V.Rep6.SalivaS012SALIVA Pool 1 PMA+SST Saliva P1 PMA+SST Saliva PMA+NASMT Saliva P1 PMA+SMT Saliva PMA+NANA
F28914.S013Day2.Rep1.SalivaS013SALIVA Pool 2 PMA-SST Saliva P2 PMA-SST Saliva PMA-NASMT Saliva P2 PMA-SMT Saliva PMA-NANA
F28914.S014Day2.Rep2.SalivaS014SALIVA Pool 2 PMA-SST Saliva P2 PMA-SST Saliva PMA-NASMT Saliva P2 PMA-SMT Saliva PMA-NANA
F28914.S015Day2.Rep3.SalivaS015SALIVA Pool 2 PMA-SST Saliva P2 PMA-SST Saliva PMA-NASMT Saliva P2 PMA-SMT Saliva PMA-NANA
F28914.S016Day2.Rep4.SalivaS016SALIVA Pool 2 PMA-SST Saliva P2 PMA-SST Saliva PMA-NASMT Saliva P2 PMA-SMT Saliva PMA-NANA
F28914.S017Day2.Rep5.SalivaS017SALIVA Pool 2 PMA-SST Saliva P2 PMA-SST Saliva PMA-NASMT Saliva P2 PMA-SMT Saliva PMA-NANA
F28914.S018Day2.Rep6.SalivaS018SALIVA Pool 2 PMA-SST Saliva P2 PMA-SST Saliva PMA-NASMT Saliva P2 PMA-SMT Saliva PMA-NANA
F28914.S019Day2.V.Rep1.SalivaS019SALIVA Pool 2 PMA+SST Saliva P2 PMA+SST Saliva PMA+NASMT Saliva P2 PMA+SMT Saliva PMA+NANA
F28914.S020Day2.V.Rep2.SalivaS020SALIVA Pool 2 PMA+SST Saliva P2 PMA+SST Saliva PMA+NASMT Saliva P2 PMA+SMT Saliva PMA+NANA
F28914.S021Day2.V.Rep3.SalivaS021SALIVA Pool 2 PMA+SST Saliva P2 PMA+SST Saliva PMA+NASMT Saliva P2 PMA+SMT Saliva PMA+NANA
F28914.S022Day2.V.Rep4.SalivaS022SALIVA Pool 2 PMA+SST Saliva P2 PMA+SST Saliva PMA+NASMT Saliva P2 PMA+SMT Saliva PMA+NANA
F28914.S023Day2.V.Rep5.SalivaS023SALIVA Pool 2 PMA+SST Saliva P2 PMA+SST Saliva PMA+NASMT Saliva P2 PMA+SMT Saliva PMA+NANA
F28914.S024Day2.V.Rep6.SalivaS024SALIVA Pool 2 PMA+SST Saliva P2 PMA+SST Saliva PMA+NASMT Saliva P2 PMA+SMT Saliva PMA+NANA
F28914.S025Day1.Rep1.SST.BiofilmS025NASST Baseline P1 PMA-SST Baseline PMA-SST Baseline PMA-NANANANA
F28914.S026Day1.Rep2.SST.BiofilmS026NASST Baseline P1 PMA-SST Baseline PMA-SST Baseline PMA-NANANANA
F28914.S027Day1.Rep3.SST.BiofilmS027NASST Baseline P1 PMA-SST Baseline PMA-SST Baseline PMA-NANANANA
F28914.S028Day1.Rep4.SST.BiofilmS028NASST Baseline P1 PMA-SST Baseline PMA-SST Baseline PMA-NANANANA
F28914.S029Day1.Rep5.SST.BiofilmS029NASST Baseline P1 PMA-SST Baseline PMA-SST Baseline PMA-NANANANA
F28914.S030Day1.Rep6.SST.BiofilmS030NASST Baseline P1 PMA-SST Baseline PMA-SST Baseline PMA-NANANANA
F28914.S031Day1.V.Rep1.SST.BiofilmS031NASST Baseline P1 PMA+SST Baseline PMA+SST Baseline PMA+NANANANA
F28914.S032Day1.V.Rep2.SST.BiofilmS032NASST Baseline P1 PMA+SST Baseline PMA+SST Baseline PMA+NANANANA
F28914.S033Day1.V.Rep3.SST.BiofilmS033NASST Baseline P1 PMA+SST Baseline PMA+SST Baseline PMA+NANANANA
F28914.S034Day1.V.Rep4.SST.BiofilmS034NASST Baseline P1 PMA+SST Baseline PMA+SST Baseline PMA+NANANANA
F28914.S035Day1.V.Rep5.SST.BiofilmS035NASST Baseline P1 PMA+SST Baseline PMA+SST Baseline PMA+NANANANA
F28914.S036Day1.V.Rep6.SST.BiofilmS036NASST Baseline P1 PMA+SST Baseline PMA+SST Baseline PMA+NANANANA
F28914.S037Day1.Rep1.SMT.BiofilmS037NANANANASMT Baseline P1 PMA-SMT Baseline PMA-SMT Baseline PMA-NA
F28914.S038Day1.Rep2.SMT.BiofilmS038NANANANASMT Baseline P1 PMA-SMT Baseline PMA-SMT Baseline PMA-NA
F28914.S039Day1.Rep3.SMT.BiofilmS039NANANANASMT Baseline P1 PMA-SMT Baseline PMA-SMT Baseline PMA-NA
F28914.S040Day1.Rep4.SMT.BiofilmS040NANANANASMT Baseline P1 PMA-SMT Baseline PMA-SMT Baseline PMA-NA
F28914.S041Day1.Rep5.SMT.BiofilmS041NANANANASMT Baseline P1 PMA-SMT Baseline PMA-SMT Baseline PMA-NA
F28914.S042Day1.Rep6.SMT.BiofilmS042NANANANASMT Baseline P1 PMA-SMT Baseline PMA-SMT Baseline PMA-NA
F28914.S043Day1.V.Rep1.SMT.BiofilmS043NANANANASMT Baseline P1 PMA+SMT Baseline PMA+SMT Baseline PMA+NA
F28914.S044Day1.V.Rep2.SMT.BiofilmS044NANANANASMT Baseline P1 PMA+SMT Baseline PMA+SMT Baseline PMA+NA
F28914.S045Day1.V.Rep3.SMT.BiofilmS045NANANANASMT Baseline P1 PMA+SMT Baseline PMA+SMT Baseline PMA+NA
F28914.S046Day1.V.Rep4.SMT.BiofilmS046NANANANASMT Baseline P1 PMA+SMT Baseline PMA+SMT Baseline PMA+NA
F28914.S047Day1.V.Rep5.SMT.BiofilmS047NANANANASMT Baseline P1 PMA+SMT Baseline PMA+SMT Baseline PMA+NA
F28914.S048Day1.V.Rep6.SMT.BiofilmS048NANANANASMT Baseline P1 PMA+SMT Baseline PMA+SMT Baseline PMA+NA
F28914.S049Day2.Rep1.SST.BiofilmS049NASST Baseline P2 PMA-SST Baseline PMA-SST Baseline PMA-NANANANA
F28914.S050Day2.Rep2.SST.BiofilmS050NASST Baseline P2 PMA-SST Baseline PMA-SST Baseline PMA-NANANANA
F28914.S051Day2.Rep3.SST.BiofilmS051NASST Baseline P2 PMA-SST Baseline PMA-SST Baseline PMA-NANANANA
F28914.S052Day2.Rep4.SST.BiofilmS052NASST Baseline P2 PMA-SST Baseline PMA-SST Baseline PMA-NANANANA
F28914.S053Day2.Rep5.SST.BiofilmS053NASST Baseline P2 PMA-SST Baseline PMA-SST Baseline PMA-NANANANA
F28914.S054Day2.Rep6.SST.BiofilmS054NASST Baseline P2 PMA-SST Baseline PMA-SST Baseline PMA-NANANANA
F28914.S055Day2.V.Rep1.SST.BiofilmS055NASST Baseline P2 PMA+SST Baseline PMA+SST Baseline PMA+NANANANA
F28914.S056Day2.V.Rep2.SST.BiofilmS056NASST Baseline P2 PMA+SST Baseline PMA+SST Baseline PMA+NANANANA
F28914.S057Day2.V.Rep3.SST.BiofilmS057NASST Baseline P2 PMA+SST Baseline PMA+SST Baseline PMA+NANANANA
F28914.S058Day2.V.Rep4.SST.BiofilmS058NASST Baseline P2 PMA+SST Baseline PMA+SST Baseline PMA+NANANANA
F28914.S059Day2.V.Rep5.SST.BiofilmS059NASST Baseline P2 PMA+SST Baseline PMA+SST Baseline PMA+NANANANA
F28914.S060Day2.V.Rep6.SST.BiofilmS060NASST Baseline P2 PMA+SST Baseline PMA+SST Baseline PMA+NANANANA
F28914.S061Day2.Rep1.SMT.BiofilmS061NANANANASMT Baseline P2 PMA-SMT Baseline PMA-SMT Baseline PMA-NA
F28914.S062Day2.Rep2.SMT.BiofilmS062NANANANASMT Baseline P2 PMA-SMT Baseline PMA-SMT Baseline PMA-NA
F28914.S063Day2.Rep3.SMT.BiofilmS063NANANANASMT Baseline P2 PMA-SMT Baseline PMA-SMT Baseline PMA-NA
F28914.S064Day2.Rep4.SMT.BiofilmS064NANANANASMT Baseline P2 PMA-SMT Baseline PMA-SMT Baseline PMA-NA
F28914.S065Day2.Rep5.SMT.BiofilmS065NANANANASMT Baseline P2 PMA-SMT Baseline PMA-SMT Baseline PMA-NA
F28914.S066Day2.Rep6.SMT.BiofilmS066NANANANASMT Baseline P2 PMA-SMT Baseline PMA-SMT Baseline PMA-NA
F28914.S067Day2.V.Rep1.SMT.BiofilmS067NANANANASMT Baseline P2 PMA+SMT Baseline PMA+SMT Baseline PMA+NA
F28914.S068Day2.V.Rep2.SMT.BiofilmS068NANANANASMT Baseline P2 PMA+SMT Baseline PMA+SMT Baseline PMA+NA
F28914.S069Day2.V.Rep3.SMT.BiofilmS069NANANANASMT Baseline P2 PMA+SMT Baseline PMA+SMT Baseline PMA+NA
F28914.S070Day2.V.Rep4.SMT.BiofilmS070NANANANASMT Baseline P2 PMA+SMT Baseline PMA+SMT Baseline PMA+NA
F28914.S071Day2.V.Rep5.SMT.BiofilmS071NANANANASMT Baseline P2 PMA+SMT Baseline PMA+SMT Baseline PMA+NA
F28914.S072Day2.V.Rep6.SMT.BiofilmS072NANANANASMT Baseline P2 PMA+SMT Baseline PMA+SMT Baseline PMA+NA
F28914.S073Day1.Plate1.Rep1.SST.AS073NANANASST Final A PMA-SST A Final PMA-NANANA
F28914.S074Day1.Plate1.Rep2.SST.AS074NANANASST Final A PMA-SST A Final PMA-NANANA
F28914.S075Day1.Plate1.Rep3.SST.AS075NANANASST Final A PMA-SST A Final PMA-NANANA
F28914.S076Day1.Plate1.Rep4.SST.AS076NANANASST Final A PMA-SST A Final PMA-NANANA
F28914.S077Day1.Plate2.Rep5.SST.AS077NANANASST Final A PMA-SST A Final PMA-NANANA
F28914.S078Day1.Plate2.Rep6.SST.AS078NANANASST Final A PMA-SST A Final PMA-NANANA
F28914.S079Day1.Plate2.Rep7.SST.AS079NANANASST Final A PMA-SST A Final PMA-NANANA
F28914.S080Day1.Plate2.Rep8.SST.AS080NANANASST Final A PMA-SST A Final PMA-NANANA
F28914.S081Day1.Plate1.Rep1.SST.BS081NANANASST Final B PMA-SST B Final PMA-NANANA
F28914.S082Day1.Plate1.Rep2.SST.BS082NANANASST Final B PMA-SST B Final PMA-NANANA
F28914.S083Day1.Plate1.Rep3.SST.BS083NANANASST Final B PMA-SST B Final PMA-NANANA
F28914.S084Day1.Plate1.Rep4.SST.BS084NANANASST Final B PMA-SST B Final PMA-NANANA
F28914.S085Day1.Plate2.Rep5.SST.BS085NANANASST Final B PMA-SST B Final PMA-NANANA
F28914.S086Day1.Plate2.Rep6.SST.BS086NANANASST Final B PMA-SST B Final PMA-NANANA
F28914.S087Day1.Plate2.Rep7.SST.BS087NANANASST Final B PMA-SST B Final PMA-NANANA
F28914.S088Day1.Plate2.Rep8.SST.BS088NANANASST Final B PMA-SST B Final PMA-NANANA
F28914.S089Day1.Plate1.Rep1.SST.CS089NANANASST Final C PMA-SST C Final PMA-NANANA
F28914.S090Day1.Plate1.Rep2.SST.CS090NANANASST Final C PMA-SST C Final PMA-NANANA
F28914.S091Day1.Plate1.Rep3.SST.CS091NANANASST Final C PMA-SST C Final PMA-NANANA
F28914.S092Day1.Plate1.Rep4.SST.CS092NANANASST Final C PMA-SST C Final PMA-NANANA
F28914.S093Day1.Plate2.Rep5.SST.CS093NANANASST Final C PMA-SST C Final PMA-NANANA
F28914.S094Day1.Plate2.Rep6.SST.CS094NANANASST Final C PMA-SST C Final PMA-NANANA
F28914.S095Day1.Plate2.Rep7.SST.CS095NANANASST Final C PMA-SST C Final PMA-NANANA
F28914.S096Day1.Plate2.Rep8.SST.CS096NANANASST Final C PMA-SST C Final PMA-NANANA
F28914.S097Day1.Plate1.Rep1.SST.DS097NANANASST Final D PMA-SST D Final PMA-NANANA
F28914.S098Day1.Plate1.Rep2.SST.DS098NANANASST Final D PMA-SST D Final PMA-NANANA
F28914.S099Day1.Plate1.Rep3.SST.DS099NANANASST Final D PMA-SST D Final PMA-NANANA
F28914.S100Day1.Plate1.Rep4.SST.DS100NANANASST Final D PMA-SST D Final PMA-NANANA
F28914.S101Day1.Plate2.Rep5.SST.DS101NANANASST Final D PMA-SST D Final PMA-NANANA
F28914.S102Day1.Plate2.Rep6.SST.DS102NANANASST Final D PMA-SST D Final PMA-NANANA
F28914.S103Day1.Plate2.Rep7.SST.DS103NANANASST Final D PMA-SST D Final PMA-NANANA
F28914.S104Day1.Plate2.Rep8.SST.DS104NANANASST Final D PMA-SST D Final PMA-NANANA
F28914.S105Day1.Plate1.Rep1.SST.ES105NANANASST Final E PMA-SST E Final PMA-NANANA
F28914.S106Day1.Plate1.Rep2.SST.ES106NANANASST Final E PMA-SST E Final PMA-NANANA
F28914.S107Day1.Plate1.Rep3.SST.ES107NANANASST Final E PMA-SST E Final PMA-NANANA
F28914.S108Day1.Plate1.Rep4.SST.ES108NANANASST Final E PMA-SST E Final PMA-NANANA
F28914.S109Day1.Plate2.Rep5.SST.ES109NANANASST Final E PMA-SST E Final PMA-NANANA
F28914.S110Day1.Plate2.Rep6.SST.ES110NANANASST Final E PMA-SST E Final PMA-NANANA
F28914.S111Day1.Plate2.Rep7.SST.ES111NANANASST Final E PMA-SST E Final PMA-NANANA
F28914.S112Day1.Plate2.Rep8.SST.ES112NANANASST Final E PMA-SST E Final PMA-NANANA
F28914.S113Day1.Plate1.Rep1.SST.FS113NANANASST Final F PMA-SST F Final PMA-NANANA
F28914.S114Day1.Plate1.Rep2.SST.FS114NANANASST Final F PMA-SST F Final PMA-NANANA
F28914.S115Day1.Plate1.Rep3.SST.FS115NANANASST Final F PMA-SST F Final PMA-NANANA
F28914.S116Day1.Plate1.Rep4.SST.FS116NANANASST Final F PMA-SST F Final PMA-NANANA
F28914.S117Day1.Plate2.Rep5.SST.FS117NANANASST Final F PMA-SST F Final PMA-NANANA
F28914.S118Day1.Plate2.Rep6.SST.FS118NANANASST Final F PMA-SST F Final PMA-NANANA
F28914.S119Day1.Plate2.Rep7.SST.FS119NANANASST Final F PMA-SST F Final PMA-NANANA
F28914.S120Day1.Plate2.Rep8.SST.FS120NANANASST Final F PMA-SST F Final PMA-NANANA
F28914.S121Day1.Plate1.Rep1.SST.GS121NANANASST Final G PMA-SST G Final PMA-NANANA
F28914.S122Day1.Plate1.Rep2.SST.GS122NANANASST Final G PMA-SST G Final PMA-NANANA
F28914.S123Day1.Plate1.Rep3.SST.GS123NANANASST Final G PMA-SST G Final PMA-NANANA
F28914.S124Day1.Plate1.Rep4.SST.GS124NANANASST Final G PMA-SST G Final PMA-NANANA
F28914.S125Day1.Plate2.Rep5.SST.GS125NANANASST Final G PMA-SST G Final PMA-NANANA
F28914.S126Day1.Plate2.Rep6.SST.GS126NANANASST Final G PMA-SST G Final PMA-NANANA
F28914.S127Day1.Plate2.Rep7.SST.GS127NANANASST Final G PMA-SST G Final PMA-NANANA
F28914.S128Day1.Plate2.Rep8.SST.GS128NANANASST Final G PMA-SST G Final PMA-NANANA
F28914.S129Day1.Plate1.Rep1.SST.HS129NANANASST Final H PMA-SST H Final PMA-NANANA
F28914.S130Day1.Plate1.Rep2.SST.HS130NANANASST Final H PMA-SST H Final PMA-NANANA
F28914.S131Day1.Plate1.Rep3.SST.HS131NANANASST Final H PMA-SST H Final PMA-NANANA
F28914.S132Day1.Plate1.Rep4.SST.HS132NANANASST Final H PMA-SST H Final PMA-NANANA
F28914.S133Day1.Plate2.Rep5.SST.HS133NANANASST Final H PMA-SST H Final PMA-NANANA
F28914.S134Day1.Plate2.Rep6.SST.HS134NANANASST Final H PMA-SST H Final PMA-NANANA
F28914.S135Day1.Plate2.Rep7.SST.HS135NANANASST Final H PMA-SST H Final PMA-NANANA
F28914.S136Day1.Plate2.Rep8.SST.HS136NANANASST Final H PMA-SST H Final PMA-NANANA
F28914.S137Day1.Plate1.Rep1.SST.IS137NANANASST Final I PMA-SST I Final PMA-NANANA
F28914.S138Day1.Plate1.Rep2.SST.IS138NANANASST Final I PMA-SST I Final PMA-NANANA
F28914.S139Day1.Plate1.Rep3.SST.IS139NANANASST Final I PMA-SST I Final PMA-NANANA
F28914.S140Day1.Plate1.Rep4.SST.IS140NANANASST Final I PMA-SST I Final PMA-NANANA
F28914.S141Day1.Plate2.Rep5.SST.IS141NANANASST Final I PMA-SST I Final PMA-NANANA
F28914.S142Day1.Plate2.Rep6.SST.IS142NANANASST Final I PMA-SST I Final PMA-NANANA
F28914.S143Day1.Plate2.Rep7.SST.IS143NANANASST Final I PMA-SST I Final PMA-NANANA
F28914.S144Day1.Plate2.Rep8.SST.IS144NANANASST Final I PMA-SST I Final PMA-NANANA
F28914.S145Day1.Plate1.Rep1.SST.JS145NANANASST Final J PMA-SST J Final PMA-NANANA
F28914.S146Day1.Plate1.Rep2.SST.JS146NANANASST Final J PMA-SST J Final PMA-NANANA
F28914.S147Day1.Plate1.Rep3.SST.JS147NANANASST Final J PMA-SST J Final PMA-NANANA
F28914.S148Day1.Plate1.Rep4.SST.JS148NANANASST Final J PMA-SST J Final PMA-NANANA
F28914.S149Day1.Plate2.Rep5.SST.JS149NANANASST Final J PMA-SST J Final PMA-NANANA
F28914.S150Day1.Plate2.Rep6.SST.JS150NANANASST Final J PMA-SST J Final PMA-NANANA
F28914.S151Day1.Plate2.Rep7.SST.JS151NANANASST Final J PMA-SST J Final PMA-NANANA
F28914.S152Day1.Plate2.Rep8.SST.JS152NANANASST Final J PMA-SST J Final PMA-NANANA
F28914.S153Day1.V.Plt1.Rep1.SST.AS153NANANASST Final A PMA+SST A Final PMA+NANANA
F28914.S154Day1.V.Plt1.Rep2.SST.AS154NANANASST Final A PMA+SST A Final PMA+NANANA
F28914.S155Day1.V.Plt1.Rep3.SST.AS155NANANASST Final A PMA+SST A Final PMA+NANANA
F28914.S156Day1.V.Plt1.Rep4.SST.AS156NANANASST Final A PMA+SST A Final PMA+NANANA
F28914.S157Day1.V.Plt2.Rep5.SST.AS157NANANASST Final A PMA+SST A Final PMA+NANANA
F28914.S158Day1.V.Plt2.Rep6.SST.AS158NANANASST Final A PMA+SST A Final PMA+NANANA
F28914.S159Day1.V.Plt2.Rep7.SST.AS159NANANASST Final A PMA+SST A Final PMA+NANANA
F28914.S160Day1.V.Plt2.Rep8.SST.AS160NANANASST Final A PMA+SST A Final PMA+NANANA
F28914.S161Day1.V.Plt1.Rep1.SST.BS161NANANASST Final B PMA+SST B Final PMA+NANANA
F28914.S162Day1.V.Plt1.Rep2.SST.BS162NANANASST Final B PMA+SST B Final PMA+NANANA
F28914.S163Day1.V.Plt1.Rep3.SST.BS163NANANASST Final B PMA+SST B Final PMA+NANANA
F28914.S164Day1.V.Plt1.Rep4.SST.BS164NANANASST Final B PMA+SST B Final PMA+NANANA
F28914.S165Day1.V.Plt2.Rep5.SST.BS165NANANASST Final B PMA+SST B Final PMA+NANANA
F28914.S166Day1.V.Plt2.Rep6.SST.BS166NANANASST Final B PMA+SST B Final PMA+NANANA
F28914.S167Day1.V.Plt2.Rep7.SST.BS167NANANASST Final B PMA+SST B Final PMA+NANANA
F28914.S168Day1.V.Plt2.Rep8.SST.BS168NANANASST Final B PMA+SST B Final PMA+NANANA
F28914.S169Day1.V.Plt1.Rep1.SST.CS169NANANASST Final C PMA+SST C Final PMA+NANANA
F28914.S170Day1.V.Plt1.Rep2.SST.CS170NANANASST Final C PMA+SST C Final PMA+NANANA
F28914.S171Day1.V.Plt1.Rep3.SST.CS171NANANASST Final C PMA+SST C Final PMA+NANANA
F28914.S172Day1.V.Plt1.Rep4.SST.CS172NANANASST Final C PMA+SST C Final PMA+NANANA
F28914.S173Day1.V.Plt2.Rep5.SST.CS173NANANASST Final C PMA+SST C Final PMA+NANANA
F28914.S174Day1.V.Plt2.Rep6.SST.CS174NANANASST Final C PMA+SST C Final PMA+NANANA
F28914.S175Day1.V.Plt2.Rep7.SST.CS175NANANASST Final C PMA+SST C Final PMA+NANANA
F28914.S176Day1.V.Plt2.Rep8.SST.CS176NANANASST Final C PMA+SST C Final PMA+NANANA
F28914.S177Day1.V.Plt1.Rep1.SST.DS177NANANASST Final D PMA+SST D Final PMA+NANANA
F28914.S178Day1.V.Plt1.Rep2.SST.DS178NANANASST Final D PMA+SST D Final PMA+NANANA
F28914.S179Day1.V.Plt1.Rep3.SST.DS179NANANASST Final D PMA+SST D Final PMA+NANANA
F28914.S180Day1.V.Plt1.Rep4.SST.DS180NANANASST Final D PMA+SST D Final PMA+NANANA
F28914.S181Day1.V.Plt2.Rep5.SST.DS181NANANASST Final D PMA+SST D Final PMA+NANANA
F28914.S182Day1.V.Plt2.Rep6.SST.DS182NANANASST Final D PMA+SST D Final PMA+NANANA
F28914.S183Day1.V.Plt2.Rep7.SST.DS183NANANASST Final D PMA+SST D Final PMA+NANANA
F28914.S184Day1.V.Plt2.Rep8.SST.DS184NANANASST Final D PMA+SST D Final PMA+NANANA
F28914.S185Day1.V.Plt1.Rep1.SST.ES185NANANASST Final E PMA+SST E Final PMA+NANANA
F28914.S186Day1.V.Plt1.Rep2.SST.ES186NANANASST Final E PMA+SST E Final PMA+NANANA
F28914.S187Day1.V.Plt1.Rep3.SST.ES187NANANASST Final E PMA+SST E Final PMA+NANANA
F28914.S188Day1.V.Plt1.Rep4.SST.ES188NANANASST Final E PMA+SST E Final PMA+NANANA
F28914.S189Day1.V.Plt2.Rep5.SST.ES189NANANASST Final E PMA+SST E Final PMA+NANANA
F28914.S190Day1.V.Plt2.Rep6.SST.ES190NANANASST Final E PMA+SST E Final PMA+NANANA
F28914.S191Day1.V.Plt2.Rep7.SST.ES191NANANASST Final E PMA+SST E Final PMA+NANANA
F28914.S192Day1.V.Plt2.Rep8.SST.ES192NANANASST Final E PMA+SST E Final PMA+NANANA
F28914.S193Day1.V.Plt1.Rep1.SST.FS193NANANASST Final F PMA+SST F Final PMA+NANANA
F28914.S194Day1.V.Plt1.Rep2.SST.FS194NANANASST Final F PMA+SST F Final PMA+NANANA
F28914.S195Day1.V.Plt1.Rep3.SST.FS195NANANASST Final F PMA+SST F Final PMA+NANANA
F28914.S196Day1.V.Plt1.Rep4.SST.FS196NANANASST Final F PMA+SST F Final PMA+NANANA
F28914.S197Day1.V.Plt2.Rep5.SST.FS197NANANASST Final F PMA+SST F Final PMA+NANANA
F28914.S198Day1.V.Plt2.Rep6.SST.FS198NANANASST Final F PMA+SST F Final PMA+NANANA
F28914.S199Day1.V.Plt2.Rep7.SST.FS199NANANASST Final F PMA+SST F Final PMA+NANANA
F28914.S200Day1.V.Plt2.Rep8.SST.FS200NANANASST Final F PMA+SST F Final PMA+NANANA
F28914.S201Day1.V.Plt1.Rep1.SST.GS201NANANASST Final G PMA+SST G Final PMA+NANANA
F28914.S202Day1.V.Plt1.Rep2.SST.GS202NANANASST Final G PMA+SST G Final PMA+NANANA
F28914.S203Day1.V.Plt1.Rep3.SST.GS203NANANASST Final G PMA+SST G Final PMA+NANANA
F28914.S204Day1.V.Plt1.Rep4.SST.GS204NANANASST Final G PMA+SST G Final PMA+NANANA
F28914.S205Day1.V.Plt2.Rep5.SST.GS205NANANASST Final G PMA+SST G Final PMA+NANANA
F28914.S206Day1.V.Plt2.Rep6.SST.GS206NANANASST Final G PMA+SST G Final PMA+NANANA
F28914.S207Day1.V.Plt2.Rep7.SST.GS207NANANASST Final G PMA+SST G Final PMA+NANANA
F28914.S208Day1.V.Plt2.Rep8.SST.GS208NANANASST Final G PMA+SST G Final PMA+NANANA
F28914.S209Day1.V.Plt1.Rep1.SST.HS209NANANASST Final H PMA+SST H Final PMA+NANANA
F28914.S210Day1.V.Plt1.Rep2.SST.HS210NANANASST Final H PMA+SST H Final PMA+NANANA
F28914.S211Day1.V.Plt1.Rep3.SST.HS211NANANASST Final H PMA+SST H Final PMA+NANANA
F28914.S212Day1.V.Plt1.Rep4.SST.HS212NANANASST Final H PMA+SST H Final PMA+NANANA
F28914.S213Day1.V.Plt2.Rep5.SST.HS213NANANASST Final H PMA+SST H Final PMA+NANANA
F28914.S214Day1.V.Plt2.Rep6.SST.HS214NANANASST Final H PMA+SST H Final PMA+NANANA
F28914.S215Day1.V.Plt2.Rep7.SST.HS215NANANASST Final H PMA+SST H Final PMA+NANANA
F28914.S216Day1.V.Plt2.Rep8.SST.HS216NANANASST Final H PMA+SST H Final PMA+NANANA
F28914.S217Day1.V.Plt1.Rep1.SST.IS217NANANASST Final I PMA+SST I Final PMA+NANANA
F28914.S218Day1.V.Plt1.Rep2.SST.IS218NANANASST Final I PMA+SST I Final PMA+NANANA
F28914.S219Day1.V.Plt1.Rep3.SST.IS219NANANASST Final I PMA+SST I Final PMA+NANANA
F28914.S220Day1.V.Plt1.Rep4.SST.IS220NANANASST Final I PMA+SST I Final PMA+NANANA
F28914.S221Day1.V.Plt2.Rep5.SST.IS221NANANASST Final I PMA+SST I Final PMA+NANANA
F28914.S222Day1.V.Plt2.Rep6.SST.IS222NANANASST Final I PMA+SST I Final PMA+NANANA
F28914.S223Day1.V.Plt2.Rep7.SST.IS223NANANASST Final I PMA+SST I Final PMA+NANANA
F28914.S224Day1.V.Plt2.Rep8.SST.IS224NANANASST Final I PMA+SST I Final PMA+NANANA
F28914.S225Day1.V.Plt1.Rep1.SST.JS225NANANASST Final J PMA+SST J Final PMA+NANANA
F28914.S226Day1.V.Plt1.Rep2.SST.JS226NANANASST Final J PMA+SST J Final PMA+NANANA
F28914.S227Day1.V.Plt1.Rep3.SST.JS227NANANASST Final J PMA+SST J Final PMA+NANANA
F28914.S228Day1.V.Plt1.Rep4.SST.JS228NANANASST Final J PMA+SST J Final PMA+NANANA
F28914.S229Day1.V.Plt2.Rep5.SST.JS229NANANASST Final J PMA+SST J Final PMA+NANANA
F28914.S230Day1.V.Plt2.Rep6.SST.JS230NANANASST Final J PMA+SST J Final PMA+NANANA
F28914.S231Day1.V.Plt2.Rep7.SST.JS231NANANASST Final J PMA+SST J Final PMA+NANANA
F28914.S232Day1.V.Plt2.Rep8.SST.JS232NANANASST Final J PMA+SST J Final PMA+NANANA
F28914.S233Day2.Plate1.Rep1.SST.AS233NANANASST Final A PMA-SST A Final PMA-NANANA
F28914.S234Day2.Plate1.Rep2.SST.AS234NANANASST Final A PMA-SST A Final PMA-NANANA
F28914.S235Day2.Plate1.Rep3.SST.AS235NANANASST Final A PMA-SST A Final PMA-NANANA
F28914.S236Day2.Plate1.Rep4.SST.AS236NANANASST Final A PMA-SST A Final PMA-NANANA
F28914.S237Day2.Plate2.Rep5.SST.AS237NANANASST Final A PMA-SST A Final PMA-NANANA
F28914.S238Day2.Plate2.Rep6.SST.AS238NANANASST Final A PMA-SST A Final PMA-NANANA
F28914.S239Day2.Plate2.Rep7.SST.AS239NANANASST Final A PMA-SST A Final PMA-NANANA
F28914.S240Day2.Plate2.Rep8.SST.AS240NANANASST Final A PMA-SST A Final PMA-NANANA
F28914.S241Day2.Plate1.Rep1.SST.BS241NANANASST Final B PMA-SST B Final PMA-NANANA
F28914.S242Day2.Plate1.Rep2.SST.BS242NANANASST Final B PMA-SST B Final PMA-NANANA
F28914.S243Day2.Plate1.Rep3.SST.BS243NANANASST Final B PMA-SST B Final PMA-NANANA
F28914.S244Day2.Plate1.Rep4.SST.BS244NANANASST Final B PMA-SST B Final PMA-NANANA
F28914.S245Day2.Plate2.Rep5.SST.BS245NANANASST Final B PMA-SST B Final PMA-NANANA
F28914.S246Day2.Plate2.Rep6.SST.BS246NANANASST Final B PMA-SST B Final PMA-NANANA
F28914.S247Day2.Plate2.Rep7.SST.BS247NANANASST Final B PMA-SST B Final PMA-NANANA
F28914.S248Day2.Plate2.Rep8.SST.BS248NANANASST Final B PMA-SST B Final PMA-NANANA
F28914.S249Day2.Plate1.Rep1.SST.CS249NANANASST Final C PMA-SST C Final PMA-NANANA
F28914.S250Day2.Plate1.Rep2.SST.CS250NANANASST Final C PMA-SST C Final PMA-NANANA
F28914.S251Day2.Plate1.Rep3.SST.CS251NANANASST Final C PMA-SST C Final PMA-NANANA
F28914.S252Day2.Plate1.Rep4.SST.CS252NANANASST Final C PMA-SST C Final PMA-NANANA
F28914.S253Day2.Plate2.Rep5.SST.CS253NANANASST Final C PMA-SST C Final PMA-NANANA
F28914.S254Day2.Plate2.Rep6.SST.CS254NANANASST Final C PMA-SST C Final PMA-NANANA
F28914.S255Day2.Plate2.Rep7.SST.CS255NANANASST Final C PMA-SST C Final PMA-NANANA
F28914.S256Day2.Plate2.Rep8.SST.CS256NANANASST Final C PMA-SST C Final PMA-NANANA
F28914.S257Day2.Plate1.Rep1.SST.DS257NANANASST Final D PMA-SST D Final PMA-NANANA
F28914.S258Day2.Plate1.Rep2.SST.DS258NANANASST Final D PMA-SST D Final PMA-NANANA
F28914.S259Day2.Plate1.Rep3.SST.DS259NANANASST Final D PMA-SST D Final PMA-NANANA
F28914.S260Day2.Plate1.Rep4.SST.DS260NANANASST Final D PMA-SST D Final PMA-NANANA
F28914.S261Day2.Plate2.Rep5.SST.DS261NANANASST Final D PMA-SST D Final PMA-NANANA
F28914.S262Day2.Plate2.Rep6.SST.DS262NANANASST Final D PMA-SST D Final PMA-NANANA
F28914.S263Day2.Plate2.Rep7.SST.DS263NANANASST Final D PMA-SST D Final PMA-NANANA
F28914.S264Day2.Plate2.Rep8.SST.DS264NANANASST Final D PMA-SST D Final PMA-NANANA
F28914.S265Day2.Plate1.Rep1.SST.ES265NANANASST Final E PMA-SST E Final PMA-NANANA
F28914.S266Day2.Plate1.Rep2.SST.ES266NANANASST Final E PMA-SST E Final PMA-NANANA
F28914.S267Day2.Plate1.Rep3.SST.ES267NANANASST Final E PMA-SST E Final PMA-NANANA
F28914.S268Day2.Plate1.Rep4.SST.ES268NANANASST Final E PMA-SST E Final PMA-NANANA
F28914.S269Day2.Plate2.Rep5.SST.ES269NANANASST Final E PMA-SST E Final PMA-NANANA
F28914.S270Day2.Plate2.Rep6.SST.ES270NANANASST Final E PMA-SST E Final PMA-NANANA
F28914.S271Day2.Plate2.Rep7.SST.ES271NANANASST Final E PMA-SST E Final PMA-NANANA
F28914.S272Day2.Plate2.Rep8.SST.ES272NANANASST Final E PMA-SST E Final PMA-NANANA
F28914.S273Day2.Plate1.Rep1.SST.FS273NANANASST Final F PMA-SST F Final PMA-NANANA
F28914.S274Day2.Plate1.Rep2.SST.FS274NANANASST Final F PMA-SST F Final PMA-NANANA
F28914.S275Day2.Plate1.Rep3.SST.FS275NANANASST Final F PMA-SST F Final PMA-NANANA
F28914.S276Day2.Plate1.Rep4.SST.FS276NANANASST Final F PMA-SST F Final PMA-NANANA
F28914.S277Day2.Plate2.Rep5.SST.FS277NANANASST Final F PMA-SST F Final PMA-NANANA
F28914.S278Day2.Plate2.Rep6.SST.FS278NANANASST Final F PMA-SST F Final PMA-NANANA
F28914.S279Day2.Plate2.Rep7.SST.FS279NANANASST Final F PMA-SST F Final PMA-NANANA
F28914.S280Day2.Plate2.Rep8.SST.FS280NANANASST Final F PMA-SST F Final PMA-NANANA
F28914.S281Day2.Plate1.Rep1.SST.GS281NANANASST Final G PMA-SST G Final PMA-NANANA
F28914.S282Day2.Plate1.Rep2.SST.GS282NANANASST Final G PMA-SST G Final PMA-NANANA
F28914.S283Day2.Plate1.Rep3.SST.GS283NANANASST Final G PMA-SST G Final PMA-NANANA
F28914.S284Day2.Plate1.Rep4.SST.GS284NANANASST Final G PMA-SST G Final PMA-NANANA
F28914.S285Day2.Plate2.Rep5.SST.GS285NANANASST Final G PMA-SST G Final PMA-NANANA
F28914.S286Day2.Plate2.Rep6.SST.GS286NANANASST Final G PMA-SST G Final PMA-NANANA
F28914.S287Day2.Plate2.Rep7.SST.GS287NANANASST Final G PMA-SST G Final PMA-NANANA
F28914.S288Day2.Plate2.Rep8.SST.GS288NANANASST Final G PMA-SST G Final PMA-NANANA
F28914.S289Day2.Plate1.Rep1.SST.HS289NANANASST Final H PMA-SST H Final PMA-NANANA
F28914.S290Day2.Plate1.Rep2.SST.HS290NANANASST Final H PMA-SST H Final PMA-NANANA
F28914.S291Day2.Plate1.Rep3.SST.HS291NANANASST Final H PMA-SST H Final PMA-NANANA
F28914.S292Day2.Plate1.Rep4.SST.HS292NANANASST Final H PMA-SST H Final PMA-NANANA
F28914.S293Day2.Plate2.Rep5.SST.HS293NANANASST Final H PMA-SST H Final PMA-NANANA
F28914.S294Day2.Plate2.Rep6.SST.HS294NANANASST Final H PMA-SST H Final PMA-NANANA
F28914.S295Day2.Plate2.Rep7.SST.HS295NANANASST Final H PMA-SST H Final PMA-NANANA
F28914.S296Day2.Plate2.Rep8.SST.HS296NANANASST Final H PMA-SST H Final PMA-NANANA
F28914.S297Day2.Plate1.Rep1.SST.IS297NANANASST Final I PMA-SST I Final PMA-NANANA
F28914.S300Day2.Plate1.Rep4.SST.IS300NANANASST Final I PMA-SST I Final PMA-NANANA
F28914.S301Day2.Plate2.Rep5.SST.IS301NANANASST Final I PMA-SST I Final PMA-NANANA
F28914.S302Day2.Plate2.Rep6.SST.IS302NANANASST Final I PMA-SST I Final PMA-NANANA
F28914.S303Day2.Plate2.Rep7.SST.IS303NANANASST Final I PMA-SST I Final PMA-NANANA
F28914.S304Day2.Plate2.Rep8.SST.IS304NANANASST Final I PMA-SST I Final PMA-NANANA
F28914.S305Day2.Plate1.Rep1.SST.JS305NANANASST Final J PMA-SST J Final PMA-NANANA
F28914.S306Day2.Plate1.Rep2.SST.JS306NANANASST Final J PMA-SST J Final PMA-NANANA
F28914.S307Day2.Plate1.Rep3.SST.JS307NANANASST Final J PMA-SST J Final PMA-NANANA
F28914.S308Day2.Plate1.Rep4.SST.JS308NANANASST Final J PMA-SST J Final PMA-NANANA
F28914.S309Day2.Plate2.Rep5.SST.JS309NANANASST Final J PMA-SST J Final PMA-NANANA
F28914.S310Day2.Plate2.Rep6.SST.JS310NANANASST Final J PMA-SST J Final PMA-NANANA
F28914.S311Day2.Plate2.Rep7.SST.JS311NANANASST Final J PMA-SST J Final PMA-NANANA
F28914.S312Day2.Plate2.Rep8.SST.JS312NANANASST Final J PMA-SST J Final PMA-NANANA
F28914.S313Day2.V.Plt1.Rep1.SST.AS313NANANASST Final A PMA+SST A Final PMA+NANANA
F28914.S314Day2.V.Plt1.Rep2.SST.AS314NANANASST Final A PMA+SST A Final PMA+NANANA
F28914.S315Day2.V.Plt1.Rep3.SST.AS315NANANASST Final A PMA+SST A Final PMA+NANANA
F28914.S316Day2.V.Plt1.Rep4.SST.AS316NANANASST Final A PMA+SST A Final PMA+NANANA
F28914.S317Day2.V.Plt2.Rep5.SST.AS317NANANASST Final A PMA+SST A Final PMA+NANANA
F28914.S318Day2.V.Plt2.Rep6.SST.AS318NANANASST Final A PMA+SST A Final PMA+NANANA
F28914.S319Day2.V.Plt2.Rep7.SST.AS319NANANASST Final A PMA+SST A Final PMA+NANANA
F28914.S320Day2.V.Plt2.Rep8.SST.AS320NANANASST Final A PMA+SST A Final PMA+NANANA
F28914.S321Day2.V.Plt1.Rep1.SST.BS321NANANASST Final B PMA+SST B Final PMA+NANANA
F28914.S322Day2.V.Plt1.Rep2.SST.BS322NANANASST Final B PMA+SST B Final PMA+NANANA
F28914.S323Day2.V.Plt1.Rep3.SST.BS323NANANASST Final B PMA+SST B Final PMA+NANANA
F28914.S324Day2.V.Plt1.Rep4.SST.BS324NANANASST Final B PMA+SST B Final PMA+NANANA
F28914.S325Day2.V.Plt2.Rep5.SST.BS325NANANASST Final B PMA+SST B Final PMA+NANANA
F28914.S326Day2.V.Plt2.Rep6.SST.BS326NANANASST Final B PMA+SST B Final PMA+NANANA
F28914.S327Day2.V.Plt2.Rep7.SST.BS327NANANASST Final B PMA+SST B Final PMA+NANANA
F28914.S328Day2.V.Plt2.Rep8.SST.BS328NANANASST Final B PMA+SST B Final PMA+NANANA
F28914.S329Day2.V.Plt1.Rep1.SST.CS329NANANASST Final C PMA+SST C Final PMA+NANANA
F28914.S330Day2.V.Plt1.Rep2.SST.CS330NANANASST Final C PMA+SST C Final PMA+NANANA
F28914.S331Day2.V.Plt1.Rep3.SST.CS331NANANASST Final C PMA+SST C Final PMA+NANANA
F28914.S332Day2.V.Plt1.Rep4.SST.CS332NANANASST Final C PMA+SST C Final PMA+NANANA
F28914.S333Day2.V.Plt2.Rep5.SST.CS333NANANASST Final C PMA+SST C Final PMA+NANANA
F28914.S334Day2.V.Plt2.Rep6.SST.CS334NANANASST Final C PMA+SST C Final PMA+NANANA
F28914.S335Day2.V.Plt2.Rep7.SST.CS335NANANASST Final C PMA+SST C Final PMA+NANANA
F28914.S336Day2.V.Plt2.Rep8.SST.CS336NANANASST Final C PMA+SST C Final PMA+NANANA
F28914.S337Day2.V.Plt1.Rep1.SST.DS337NANANASST Final D PMA+SST D Final PMA+NANANA
F28914.S338Day2.V.Plt1.Rep2.SST.DS338NANANASST Final D PMA+SST D Final PMA+NANANA
F28914.S339Day2.V.Plt1.Rep3.SST.DS339NANANASST Final D PMA+SST D Final PMA+NANANA
F28914.S340Day2.V.Plt1.Rep4.SST.DS340NANANASST Final D PMA+SST D Final PMA+NANANA
F28914.S341Day2.V.Plt2.Rep5.SST.DS341NANANASST Final D PMA+SST D Final PMA+NANANA
F28914.S342Day2.V.Plt2.Rep6.SST.DS342NANANASST Final D PMA+SST D Final PMA+NANANA
F28914.S343Day2.V.Plt2.Rep7.SST.DS343NANANASST Final D PMA+SST D Final PMA+NANANA
F28914.S344Day2.V.Plt2.Rep8.SST.DS344NANANASST Final D PMA+SST D Final PMA+NANANA
F28914.S345Day2.V.Plt1.Rep1.SST.ES345NANANASST Final E PMA+SST E Final PMA+NANANA
F28914.S346Day2.V.Plt1.Rep2.SST.ES346NANANASST Final E PMA+SST E Final PMA+NANANA
F28914.S347Day2.V.Plt1.Rep3.SST.ES347NANANASST Final E PMA+SST E Final PMA+NANANA
F28914.S348Day2.V.Plt1.Rep4.SST.ES348NANANASST Final E PMA+SST E Final PMA+NANANA
F28914.S349Day2.V.Plt2.Rep5.SST.ES349NANANASST Final E PMA+SST E Final PMA+NANANA
F28914.S350Day2.V.Plt2.Rep6.SST.ES350NANANASST Final E PMA+SST E Final PMA+NANANA
F28914.S351Day2.V.Plt2.Rep7.SST.ES351NANANASST Final E PMA+SST E Final PMA+NANANA
F28914.S352Day2.V.Plt2.Rep8.SST.ES352NANANASST Final E PMA+SST E Final PMA+NANANA
F28914.S353Day2.V.Plt1.Rep1.SST.FS353NANANASST Final F PMA+SST F Final PMA+NANANA
F28914.S354Day2.V.Plt1.Rep2.SST.FS354NANANASST Final F PMA+SST F Final PMA+NANANA
F28914.S355Day2.V.Plt1.Rep3.SST.FS355NANANASST Final F PMA+SST F Final PMA+NANANA
F28914.S356Day2.V.Plt1.Rep4.SST.FS356NANANASST Final F PMA+SST F Final PMA+NANANA
F28914.S357Day2.V.Plt2.Rep5.SST.FS357NANANASST Final F PMA+SST F Final PMA+NANANA
F28914.S358Day2.V.Plt2.Rep6.SST.FS358NANANASST Final F PMA+SST F Final PMA+NANANA
F28914.S359Day2.V.Plt2.Rep7.SST.FS359NANANASST Final F PMA+SST F Final PMA+NANANA
F28914.S360Day2.V.Plt2.Rep8.SST.FS360NANANASST Final F PMA+SST F Final PMA+NANANA
F28914.S361Day2.V.Plt1.Rep1.SST.GS361NANANASST Final G PMA+SST G Final PMA+NANANA
F28914.S362Day2.V.Plt1.Rep2.SST.GS362NANANASST Final G PMA+SST G Final PMA+NANANA
F28914.S363Day2.V.Plt1.Rep3.SST.GS363NANANASST Final G PMA+SST G Final PMA+NANANA
F28914.S364Day2.V.Plt1.Rep4.SST.GS364NANANASST Final G PMA+SST G Final PMA+NANANA
F28914.S365Day2.V.Plt2.Rep5.SST.GS365NANANASST Final G PMA+SST G Final PMA+NANANA
F28914.S366Day2.V.Plt2.Rep6.SST.GS366NANANASST Final G PMA+SST G Final PMA+NANANA
F28914.S367Day2.V.Plt2.Rep7.SST.GS367NANANASST Final G PMA+SST G Final PMA+NANANA
F28914.S368Day2.V.Plt2.Rep8.SST.GS368NANANASST Final G PMA+SST G Final PMA+NANANA
F28914.S369Day2.V.Plt1.Rep1.SST.HS369NANANASST Final H PMA+SST H Final PMA+NANANA
F28914.S370Day2.V.Plt1.Rep2.SST.HS370NANANASST Final H PMA+SST H Final PMA+NANANA
F28914.S371Day2.V.Plt1.Rep3.SST.HS371NANANASST Final H PMA+SST H Final PMA+NANANA
F28914.S372Day2.V.Plt1.Rep4.SST.HS372NANANASST Final H PMA+SST H Final PMA+NANANA
F28914.S373Day2.V.Plt2.Rep5.SST.HS373NANANASST Final H PMA+SST H Final PMA+NANANA
F28914.S374Day2.V.Plt2.Rep6.SST.HS374NANANASST Final H PMA+SST H Final PMA+NANANA
F28914.S375Day2.V.Plt2.Rep7.SST.HS375NANANASST Final H PMA+SST H Final PMA+NANANA
F28914.S376Day2.V.Plt2.Rep8.SST.HS376NANANASST Final H PMA+SST H Final PMA+NANANA
F28914.S377Day2.V.Plt1.Rep1.SST.IS377NANANASST Final I PMA+SST I Final PMA+NANANA
F28914.S378Day2.V.Plt1.Rep2.SST.IS378NANANASST Final I PMA+SST I Final PMA+NANANA
F28914.S379Day2.V.Plt1.Rep3.SST.IS379NANANASST Final I PMA+SST I Final PMA+NANANA
F28914.S380Day2.V.Plt1.Rep4.SST.IS380NANANASST Final I PMA+SST I Final PMA+NANANA
F28914.S381Day2.V.Plt2.Rep5.SST.IS381NANANASST Final I PMA+SST I Final PMA+NANANA
F28914.S382Day2.V.Plt2.Rep6.SST.IS382NANANASST Final I PMA+SST I Final PMA+NANANA
F28914.S383Day2.V.Plt2.Rep7.SST.IS383NANANASST Final I PMA+SST I Final PMA+NANANA
F28914.S384Day2.V.Plt2.Rep8.SST.IS384NANANASST Final I PMA+SST I Final PMA+NANANA
F28914.S385Day2.V.Plt1.Rep1.SST.JS385NANANASST Final J PMA+SST J Final PMA+NANANA
F28914.S386Day2.V.Plt1.Rep2.SST.JS386NANANASST Final J PMA+SST J Final PMA+NANANA
F28914.S387Day2.V.Plt1.Rep3.SST.JS387NANANASST Final J PMA+SST J Final PMA+NANANA
F28914.S388Day2.V.Plt1.Rep4.SST.JS388NANANASST Final J PMA+SST J Final PMA+NANANA
F28914.S389Day2.V.Plt2.Rep5.SST.JS389NANANASST Final J PMA+SST J Final PMA+NANANA
F28914.S390Day2.V.Plt2.Rep6.SST.JS390NANANASST Final J PMA+SST J Final PMA+NANANA
F28914.S391Day2.V.Plt2.Rep7.SST.JS391NANANASST Final J PMA+SST J Final PMA+NANANA
F28914.S392Day2.V.Plt2.Rep8.SST.JS392NANANASST Final J PMA+SST J Final PMA+NANANA
F28914.S393Day1.Plate1.Rep1.SMT.AS393NANANANANANASMT Final A PMA-SMT A Final PMA-
F28914.S394Day1.Plate1.Rep2.SMT.AS394NANANANANANASMT Final A PMA-SMT A Final PMA-
F28914.S395Day1.Plate1.Rep3.SMT.AS395NANANANANANASMT Final A PMA-SMT A Final PMA-
F28914.S396Day1.Plate1.Rep4.SMT.AS396NANANANANANASMT Final A PMA-SMT A Final PMA-
F28914.S397Day1.Plate2.Rep5.SMT.AS397NANANANANANASMT Final A PMA-SMT A Final PMA-
F28914.S398Day1.Plate2.Rep6.SMT.AS398NANANANANANASMT Final A PMA-SMT A Final PMA-
F28914.S399Day1.Plate2.Rep7.SMT.AS399NANANANANANASMT Final A PMA-SMT A Final PMA-
F28914.S400Day1.Plate2.Rep8.SMT.AS400NANANANANANASMT Final A PMA-SMT A Final PMA-
F28914.S401Day1.Plate1.Rep1.SMT.BS401NANANANANANASMT Final B PMA-SMT B Final PMA-
F28914.S402Day1.Plate1.Rep2.SMT.BS402NANANANANANASMT Final B PMA-SMT B Final PMA-
F28914.S403Day1.Plate1.Rep3.SMT.BS403NANANANANANASMT Final B PMA-SMT B Final PMA-
F28914.S404Day1.Plate1.Rep4.SMT.BS404NANANANANANASMT Final B PMA-SMT B Final PMA-
F28914.S405Day1.Plate2.Rep5.SMT.BS405NANANANANANASMT Final B PMA-SMT B Final PMA-
F28914.S406Day1.Plate2.Rep6.SMT.BS406NANANANANANASMT Final B PMA-SMT B Final PMA-
F28914.S407Day1.Plate2.Rep7.SMT.BS407NANANANANANASMT Final B PMA-SMT B Final PMA-
F28914.S408Day1.Plate2.Rep8.SMT.BS408NANANANANANASMT Final B PMA-SMT B Final PMA-
F28914.S409Day1.Plate1.Rep1.SMT.CS409NANANANANANASMT Final C PMA-SMT C Final PMA-
F28914.S410Day1.Plate1.Rep2.SMT.CS410NANANANANANASMT Final C PMA-SMT C Final PMA-
F28914.S411Day1.Plate1.Rep3.SMT.CS411NANANANANANASMT Final C PMA-SMT C Final PMA-
F28914.S412Day1.Plate1.Rep4.SMT.CS412NANANANANANASMT Final C PMA-SMT C Final PMA-
F28914.S413Day1.Plate2.Rep5.SMT.CS413NANANANANANASMT Final C PMA-SMT C Final PMA-
F28914.S414Day1.Plate2.Rep6.SMT.CS414NANANANANANASMT Final C PMA-SMT C Final PMA-
F28914.S415Day1.Plate2.Rep7.SMT.CS415NANANANANANASMT Final C PMA-SMT C Final PMA-
F28914.S416Day1.Plate2.Rep8.SMT.CS416NANANANANANASMT Final C PMA-SMT C Final PMA-
F28914.S417Day1.Plate1.Rep1.SMT.DS417NANANANANANASMT Final D PMA-SMT D Final PMA-
F28914.S418Day1.Plate1.Rep2.SMT.DS418NANANANANANASMT Final D PMA-SMT D Final PMA-
F28914.S419Day1.Plate1.Rep3.SMT.DS419NANANANANANASMT Final D PMA-SMT D Final PMA-
F28914.S420Day1.Plate1.Rep4.SMT.DS420NANANANANANASMT Final D PMA-SMT D Final PMA-
F28914.S421Day1.Plate2.Rep5.SMT.DS421NANANANANANASMT Final D PMA-SMT D Final PMA-
F28914.S422Day1.Plate2.Rep6.SMT.DS422NANANANANANASMT Final D PMA-SMT D Final PMA-
F28914.S423Day1.Plate2.Rep7.SMT.DS423NANANANANANASMT Final D PMA-SMT D Final PMA-
F28914.S424Day1.Plate2.Rep8.SMT.DS424NANANANANANASMT Final D PMA-SMT D Final PMA-
F28914.S425Day1.Plate1.Rep1.SMT.ES425NANANANANANASMT Final E PMA-SMT E Final PMA-
F28914.S426Day1.Plate1.Rep2.SMT.ES426NANANANANANASMT Final E PMA-SMT E Final PMA-
F28914.S427Day1.Plate1.Rep3.SMT.ES427NANANANANANASMT Final E PMA-SMT E Final PMA-
F28914.S428Day1.Plate1.Rep4.SMT.ES428NANANANANANASMT Final E PMA-SMT E Final PMA-
F28914.S429Day1.Plate2.Rep5.SMT.ES429NANANANANANASMT Final E PMA-SMT E Final PMA-
F28914.S430Day1.Plate2.Rep6.SMT.ES430NANANANANANASMT Final E PMA-SMT E Final PMA-
F28914.S431Day1.Plate2.Rep7.SMT.ES431NANANANANANASMT Final E PMA-SMT E Final PMA-
F28914.S432Day1.Plate2.Rep8.SMT.ES432NANANANANANASMT Final E PMA-SMT E Final PMA-
F28914.S433Day1.Plate1.Rep1.SMT.FS433NANANANANANASMT Final F PMA-SMT F Final PMA-
F28914.S434Day1.Plate1.Rep2.SMT.FS434NANANANANANASMT Final F PMA-SMT F Final PMA-
F28914.S435Day1.Plate1.Rep3.SMT.FS435NANANANANANASMT Final F PMA-SMT F Final PMA-
F28914.S436Day1.Plate1.Rep4.SMT.FS436NANANANANANASMT Final F PMA-SMT F Final PMA-
F28914.S437Day1.Plate2.Rep5.SMT.FS437NANANANANANASMT Final F PMA-SMT F Final PMA-
F28914.S438Day1.Plate2.Rep6.SMT.FS438NANANANANANASMT Final F PMA-SMT F Final PMA-
F28914.S439Day1.Plate2.Rep7.SMT.FS439NANANANANANASMT Final F PMA-SMT F Final PMA-
F28914.S440Day1.Plate2.Rep8.SMT.FS440NANANANANANASMT Final F PMA-SMT F Final PMA-
F28914.S441Day1.Plate1.Rep1.SMT.GS441NANANANANANASMT Final G PMA-SMT G Final PMA-
F28914.S442Day1.Plate1.Rep2.SMT.GS442NANANANANANASMT Final G PMA-SMT G Final PMA-
F28914.S443Day1.Plate1.Rep3.SMT.GS443NANANANANANASMT Final G PMA-SMT G Final PMA-
F28914.S444Day1.Plate1.Rep4.SMT.GS444NANANANANANASMT Final G PMA-SMT G Final PMA-
F28914.S445Day1.Plate2.Rep5.SMT.GS445NANANANANANASMT Final G PMA-SMT G Final PMA-
F28914.S446Day1.Plate2.Rep6.SMT.GS446NANANANANANASMT Final G PMA-SMT G Final PMA-
F28914.S447Day1.Plate2.Rep7.SMT.GS447NANANANANANASMT Final G PMA-SMT G Final PMA-
F28914.S448Day1.Plate2.Rep8.SMT.GS448NANANANANANASMT Final G PMA-SMT G Final PMA-
F28914.S449Day1.Plate1.Rep1.SMT.HS449NANANANANANASMT Final H PMA-SMT H Final PMA-
F28914.S450Day1.Plate1.Rep2.SMT.HS450NANANANANANASMT Final H PMA-SMT H Final PMA-
F28914.S451Day1.Plate1.Rep3.SMT.HS451NANANANANANASMT Final H PMA-SMT H Final PMA-
F28914.S452Day1.Plate1.Rep4.SMT.HS452NANANANANANASMT Final H PMA-SMT H Final PMA-
F28914.S453Day1.Plate2.Rep5.SMT.HS453NANANANANANASMT Final H PMA-SMT H Final PMA-
F28914.S454Day1.Plate2.Rep6.SMT.HS454NANANANANANASMT Final H PMA-SMT H Final PMA-
F28914.S455Day1.Plate2.Rep7.SMT.HS455NANANANANANASMT Final H PMA-SMT H Final PMA-
F28914.S456Day1.Plate2.Rep8.SMT.HS456NANANANANANASMT Final H PMA-SMT H Final PMA-
F28914.S457Day1.Plate1.Rep1.SMT.IS457NANANANANANASMT Final I PMA-SMT I Final PMA-
F28914.S458Day1.Plate1.Rep2.SMT.IS458NANANANANANASMT Final I PMA-SMT I Final PMA-
F28914.S459Day1.Plate1.Rep3.SMT.IS459NANANANANANASMT Final I PMA-SMT I Final PMA-
F28914.S460Day1.Plate1.Rep4.SMT.IS460NANANANANANASMT Final I PMA-SMT I Final PMA-
F28914.S461Day1.Plate2.Rep5.SMT.IS461NANANANANANASMT Final I PMA-SMT I Final PMA-
F28914.S462Day1.Plate2.Rep6.SMT.IS462NANANANANANASMT Final I PMA-SMT I Final PMA-
F28914.S463Day1.Plate2.Rep7.SMT.IS463NANANANANANASMT Final I PMA-SMT I Final PMA-
F28914.S464Day1.Plate2.Rep8.SMT.IS464NANANANANANASMT Final I PMA-SMT I Final PMA-
F28914.S465Day1.Plate1.Rep1.SMT.JS465NANANANANANASMT Final J PMA-SMT J Final PMA-
F28914.S466Day1.Plate1.Rep2.SMT.JS466NANANANANANASMT Final J PMA-SMT J Final PMA-
F28914.S467Day1.Plate1.Rep3.SMT.JS467NANANANANANASMT Final J PMA-SMT J Final PMA-
F28914.S468Day1.Plate1.Rep4.SMT.JS468NANANANANANASMT Final J PMA-SMT J Final PMA-
F28914.S469Day1.Plate2.Rep5.SMT.JS469NANANANANANASMT Final J PMA-SMT J Final PMA-
F28914.S470Day1.Plate2.Rep6.SMT.JS470NANANANANANASMT Final J PMA-SMT J Final PMA-
F28914.S471Day1.Plate2.Rep7.SMT.JS471NANANANANANASMT Final J PMA-SMT J Final PMA-
F28914.S472Day1.Plate2.Rep8.SMT.JS472NANANANANANASMT Final J PMA-SMT J Final PMA-
F28914.S473Day1.V.Plt1.Rep1.SMT.AS473NANANANANANASMT Final A PMA+SMT A Final PMA+
F28914.S474Day1.V.Plt1.Rep2.SMT.AS474NANANANANANASMT Final A PMA+SMT A Final PMA+
F28914.S475Day1.V.Plt1.Rep3.SMT.AS475NANANANANANASMT Final A PMA+SMT A Final PMA+
F28914.S476Day1.V.Plt1.Rep4.SMT.AS476NANANANANANASMT Final A PMA+SMT A Final PMA+
F28914.S477Day1.V.Plt2.Rep5.SMT.AS477NANANANANANASMT Final A PMA+SMT A Final PMA+
F28914.S478Day1.V.Plt2.Rep6.SMT.AS478NANANANANANASMT Final A PMA+SMT A Final PMA+
F28914.S479Day1.V.Plt2.Rep7.SMT.AS479NANANANANANASMT Final A PMA+SMT A Final PMA+
F28914.S480Day1.V.Plt2.Rep8.SMT.AS480NANANANANANASMT Final A PMA+SMT A Final PMA+
F28914.S481Day1.V.Plt1.Rep1.SMT.BS481NANANANANANASMT Final B PMA+SMT B Final PMA+
F28914.S482Day1.V.Plt1.Rep2.SMT.BS482NANANANANANASMT Final B PMA+SMT B Final PMA+
F28914.S483Day1.V.Plt1.Rep3.SMT.BS483NANANANANANASMT Final B PMA+SMT B Final PMA+
F28914.S484Day1.V.Plt1.Rep4.SMT.BS484NANANANANANASMT Final B PMA+SMT B Final PMA+
F28914.S485Day1.V.Plt2.Rep5.SMT.BS485NANANANANANASMT Final B PMA+SMT B Final PMA+
F28914.S486Day1.V.Plt2.Rep6.SMT.BS486NANANANANANASMT Final B PMA+SMT B Final PMA+
F28914.S487Day1.V.Plt2.Rep7.SMT.BS487NANANANANANASMT Final B PMA+SMT B Final PMA+
F28914.S488Day1.V.Plt2.Rep8.SMT.BS488NANANANANANASMT Final B PMA+SMT B Final PMA+
F28914.S489Day1.V.Plt1.Rep1.SMT.CS489NANANANANANASMT Final C PMA+SMT C Final PMA+
F28914.S490Day1.V.Plt1.Rep2.SMT.CS490NANANANANANASMT Final C PMA+SMT C Final PMA+
F28914.S491Day1.V.Plt1.Rep3.SMT.CS491NANANANANANASMT Final C PMA+SMT C Final PMA+
F28914.S492Day1.V.Plt1.Rep4.SMT.CS492NANANANANANASMT Final C PMA+SMT C Final PMA+
F28914.S493Day1.V.Plt2.Rep5.SMT.CS493NANANANANANASMT Final C PMA+SMT C Final PMA+
F28914.S494Day1.V.Plt2.Rep6.SMT.CS494NANANANANANASMT Final C PMA+SMT C Final PMA+
F28914.S495Day1.V.Plt2.Rep7.SMT.CS495NANANANANANASMT Final C PMA+SMT C Final PMA+
F28914.S496Day1.V.Plt2.Rep8.SMT.CS496NANANANANANASMT Final C PMA+SMT C Final PMA+
F28914.S497Day1.V.Plt1.Rep1.SMT.DS497NANANANANANASMT Final D PMA+SMT D Final PMA+
F28914.S498Day1.V.Plt1.Rep2.SMT.DS498NANANANANANASMT Final D PMA+SMT D Final PMA+
F28914.S499Day1.V.Plt1.Rep3.SMT.DS499NANANANANANASMT Final D PMA+SMT D Final PMA+
F28914.S500Day1.V.Plt1.Rep4.SMT.DS500NANANANANANASMT Final D PMA+SMT D Final PMA+
F28914.S501Day1.V.Plt2.Rep5.SMT.DS501NANANANANANASMT Final D PMA+SMT D Final PMA+
F28914.S502Day1.V.Plt2.Rep6.SMT.DS502NANANANANANASMT Final D PMA+SMT D Final PMA+
F28914.S503Day1.V.Plt2.Rep7.SMT.DS503NANANANANANASMT Final D PMA+SMT D Final PMA+
F28914.S504Day1.V.Plt2.Rep8.SMT.DS504NANANANANANASMT Final D PMA+SMT D Final PMA+
F28914.S505Day1.V.Plt1.Rep1.SMT.ES505NANANANANANASMT Final E PMA+SMT E Final PMA+
F28914.S506Day1.V.Plt1.Rep2.SMT.ES506NANANANANANASMT Final E PMA+SMT E Final PMA+
F28914.S507Day1.V.Plt1.Rep3.SMT.ES507NANANANANANASMT Final E PMA+SMT E Final PMA+
F28914.S508Day1.V.Plt1.Rep4.SMT.ES508NANANANANANASMT Final E PMA+SMT E Final PMA+
F28914.S509Day1.V.Plt2.Rep5.SMT.ES509NANANANANANASMT Final E PMA+SMT E Final PMA+
F28914.S510Day1.V.Plt2.Rep6.SMT.ES510NANANANANANASMT Final E PMA+SMT E Final PMA+
F28914.S511Day1.V.Plt2.Rep7.SMT.ES511NANANANANANASMT Final E PMA+SMT E Final PMA+
F28914.S512Day1.V.Plt2.Rep8.SMT.ES512NANANANANANASMT Final E PMA+SMT E Final PMA+
F28914.S513Day1.V.Plt1.Rep1.SMT.FS513NANANANANANASMT Final F PMA+SMT F Final PMA+
F28914.S514Day1.V.Plt1.Rep2.SMT.FS514NANANANANANASMT Final F PMA+SMT F Final PMA+
F28914.S515Day1.V.Plt1.Rep3.SMT.FS515NANANANANANASMT Final F PMA+SMT F Final PMA+
F28914.S516Day1.V.Plt1.Rep4.SMT.FS516NANANANANANASMT Final F PMA+SMT F Final PMA+
F28914.S517Day1.V.Plt2.Rep5.SMT.FS517NANANANANANASMT Final F PMA+SMT F Final PMA+
F28914.S518Day1.V.Plt2.Rep6.SMT.FS518NANANANANANASMT Final F PMA+SMT F Final PMA+
F28914.S519Day1.V.Plt2.Rep7.SMT.FS519NANANANANANASMT Final F PMA+SMT F Final PMA+
F28914.S520Day1.V.Plt2.Rep8.SMT.FS520NANANANANANASMT Final F PMA+SMT F Final PMA+
F28914.S521Day1.V.Plt1.Rep1.SMT.GS521NANANANANANASMT Final G PMA+SMT G Final PMA+
F28914.S522Day1.V.Plt1.Rep2.SMT.GS522NANANANANANASMT Final G PMA+SMT G Final PMA+
F28914.S523Day1.V.Plt1.Rep3.SMT.GS523NANANANANANASMT Final G PMA+SMT G Final PMA+
F28914.S524Day1.V.Plt1.Rep4.SMT.GS524NANANANANANASMT Final G PMA+SMT G Final PMA+
F28914.S525Day1.V.Plt2.Rep5.SMT.GS525NANANANANANASMT Final G PMA+SMT G Final PMA+
F28914.S526Day1.V.Plt2.Rep6.SMT.GS526NANANANANANASMT Final G PMA+SMT G Final PMA+
F28914.S527Day1.V.Plt2.Rep7.SMT.GS527NANANANANANASMT Final G PMA+SMT G Final PMA+
F28914.S528Day1.V.Plt2.Rep8.SMT.GS528NANANANANANASMT Final G PMA+SMT G Final PMA+
F28914.S529Day1.V.Plt1.Rep1.SMT.HS529NANANANANANASMT Final H PMA+SMT H Final PMA+
F28914.S530Day1.V.Plt1.Rep2.SMT.HS530NANANANANANASMT Final H PMA+SMT H Final PMA+
F28914.S531Day1.V.Plt1.Rep3.SMT.HS531NANANANANANASMT Final H PMA+SMT H Final PMA+
F28914.S532Day1.V.Plt1.Rep4.SMT.HS532NANANANANANASMT Final H PMA+SMT H Final PMA+
F28914.S533Day1.V.Plt2.Rep5.SMT.HS533NANANANANANASMT Final H PMA+SMT H Final PMA+
F28914.S534Day1.V.Plt2.Rep6.SMT.HS534NANANANANANASMT Final H PMA+SMT H Final PMA+
F28914.S535Day1.V.Plt2.Rep7.SMT.HS535NANANANANANASMT Final H PMA+SMT H Final PMA+
F28914.S536Day1.V.Plt2.Rep8.SMT.HS536NANANANANANASMT Final H PMA+SMT H Final PMA+
F28914.S537Day1.V.Plt1.Rep1.SMT.IS537NANANANANANASMT Final I PMA+SMT I Final PMA+
F28914.S538Day1.V.Plt1.Rep2.SMT.IS538NANANANANANASMT Final I PMA+SMT I Final PMA+
F28914.S539Day1.V.Plt1.Rep3.SMT.IS539NANANANANANASMT Final I PMA+SMT I Final PMA+
F28914.S540Day1.V.Plt1.Rep4.SMT.IS540NANANANANANASMT Final I PMA+SMT I Final PMA+
F28914.S541Day1.V.Plt2.Rep5.SMT.IS541NANANANANANASMT Final I PMA+SMT I Final PMA+
F28914.S542Day1.V.Plt2.Rep6.SMT.IS542NANANANANANASMT Final I PMA+SMT I Final PMA+
F28914.S543Day1.V.Plt2.Rep7.SMT.IS543NANANANANANASMT Final I PMA+SMT I Final PMA+
F28914.S544Day1.V.Plt2.Rep8.SMT.IS544NANANANANANASMT Final I PMA+SMT I Final PMA+
F28914.S545Day1.V.Plt1.Rep1.SMT.JS545NANANANANANASMT Final J PMA+SMT J Final PMA+
F28914.S546Day1.V.Plt1.Rep2.SMT.JS546NANANANANANASMT Final J PMA+SMT J Final PMA+
F28914.S547Day1.V.Plt1.Rep3.SMT.JS547NANANANANANASMT Final J PMA+SMT J Final PMA+
F28914.S548Day1.V.Plt1.Rep4.SMT.JS548NANANANANANASMT Final J PMA+SMT J Final PMA+
F28914.S549Day1.V.Plt2.Rep5.SMT.JS549NANANANANANASMT Final J PMA+SMT J Final PMA+
F28914.S550Day1.V.Plt2.Rep6.SMT.JS550NANANANANANASMT Final J PMA+SMT J Final PMA+
F28914.S551Day1.V.Plt2.Rep7.SMT.JS551NANANANANANASMT Final J PMA+SMT J Final PMA+
F28914.S552Day1.V.Plt2.Rep8.SMT.JS552NANANANANANASMT Final J PMA+SMT J Final PMA+
F28914.S553Day2.Plate1.Rep1.SMT.AS553NANANANANANASMT Final A PMA-SMT A Final PMA-
F28914.S554Day2.Plate1.Rep2.SMT.AS554NANANANANANASMT Final A PMA-SMT A Final PMA-
F28914.S555Day2.Plate1.Rep3.SMT.AS555NANANANANANASMT Final A PMA-SMT A Final PMA-
F28914.S556Day2.Plate1.Rep4.SMT.AS556NANANANANANASMT Final A PMA-SMT A Final PMA-
F28914.S557Day2.Plate2.Rep5.SMT.AS557NANANANANANASMT Final A PMA-SMT A Final PMA-
F28914.S558Day2.Plate2.Rep6.SMT.AS558NANANANANANASMT Final A PMA-SMT A Final PMA-
F28914.S559Day2.Plate2.Rep7.SMT.AS559NANANANANANASMT Final A PMA-SMT A Final PMA-
F28914.S560Day2.Plate2.Rep8.SMT.AS560NANANANANANASMT Final A PMA-SMT A Final PMA-
F28914.S561Day2.Plate1.Rep1.SMT.BS561NANANANANANASMT Final B PMA-SMT B Final PMA-
F28914.S562Day2.Plate1.Rep2.SMT.BS562NANANANANANASMT Final B PMA-SMT B Final PMA-
F28914.S563Day2.Plate1.Rep3.SMT.BS563NANANANANANASMT Final B PMA-SMT B Final PMA-
F28914.S564Day2.Plate1.Rep4.SMT.BS564NANANANANANASMT Final B PMA-SMT B Final PMA-
F28914.S565Day2.Plate2.Rep5.SMT.BS565NANANANANANASMT Final B PMA-SMT B Final PMA-
F28914.S566Day2.Plate2.Rep6.SMT.BS566NANANANANANASMT Final B PMA-SMT B Final PMA-
F28914.S567Day2.Plate2.Rep7.SMT.BS567NANANANANANASMT Final B PMA-SMT B Final PMA-
F28914.S568Day2.Plate2.Rep8.SMT.BS568NANANANANANASMT Final B PMA-SMT B Final PMA-
F28914.S569Day2.Plate1.Rep1.SMT.CS569NANANANANANASMT Final C PMA-SMT C Final PMA-
F28914.S570Day2.Plate1.Rep2.SMT.CS570NANANANANANASMT Final C PMA-SMT C Final PMA-
F28914.S571Day2.Plate1.Rep3.SMT.CS571NANANANANANASMT Final C PMA-SMT C Final PMA-
F28914.S572Day2.Plate1.Rep4.SMT.CS572NANANANANANASMT Final C PMA-SMT C Final PMA-
F28914.S573Day2.Plate2.Rep5.SMT.CS573NANANANANANASMT Final C PMA-SMT C Final PMA-
F28914.S574Day2.Plate2.Rep6.SMT.CS574NANANANANANASMT Final C PMA-SMT C Final PMA-
F28914.S575Day2.Plate2.Rep7.SMT.CS575NANANANANANASMT Final C PMA-SMT C Final PMA-
F28914.S576Day2.Plate2.Rep8.SMT.CS576NANANANANANASMT Final C PMA-SMT C Final PMA-
F28914.S577Day2.Plate1.Rep1.SMT.DS577NANANANANANASMT Final D PMA-SMT D Final PMA-
F28914.S578Day2.Plate1.Rep2.SMT.DS578NANANANANANASMT Final D PMA-SMT D Final PMA-
F28914.S579Day2.Plate1.Rep3.SMT.DS579NANANANANANASMT Final D PMA-SMT D Final PMA-
F28914.S580Day2.Plate1.Rep4.SMT.DS580NANANANANANASMT Final D PMA-SMT D Final PMA-
F28914.S581Day2.Plate2.Rep5.SMT.DS581NANANANANANASMT Final D PMA-SMT D Final PMA-
F28914.S582Day2.Plate2.Rep6.SMT.DS582NANANANANANASMT Final D PMA-SMT D Final PMA-
F28914.S583Day2.Plate2.Rep7.SMT.DS583NANANANANANASMT Final D PMA-SMT D Final PMA-
F28914.S584Day2.Plate2.Rep8.SMT.DS584NANANANANANASMT Final D PMA-SMT D Final PMA-
F28914.S585Day2.Plate1.Rep1.SMT.ES585NANANANANANASMT Final E PMA-SMT E Final PMA-
F28914.S586Day2.Plate1.Rep2.SMT.ES586NANANANANANASMT Final E PMA-SMT E Final PMA-
F28914.S587Day2.Plate1.Rep3.SMT.ES587NANANANANANASMT Final E PMA-SMT E Final PMA-
F28914.S588Day2.Plate1.Rep4.SMT.ES588NANANANANANASMT Final E PMA-SMT E Final PMA-
F28914.S589Day2.Plate2.Rep5.SMT.ES589NANANANANANASMT Final E PMA-SMT E Final PMA-
F28914.S590Day2.Plate2.Rep6.SMT.ES590NANANANANANASMT Final E PMA-SMT E Final PMA-
F28914.S591Day2.Plate2.Rep7.SMT.ES591NANANANANANASMT Final E PMA-SMT E Final PMA-
F28914.S592Day2.Plate2.Rep8.SMT.ES592NANANANANANASMT Final E PMA-SMT E Final PMA-
F28914.S593Day2.Plate1.Rep1.SMT.FS593NANANANANANASMT Final F PMA-SMT F Final PMA-
F28914.S594Day2.Plate1.Rep2.SMT.FS594NANANANANANASMT Final F PMA-SMT F Final PMA-
F28914.S595Day2.Plate1.Rep3.SMT.FS595NANANANANANASMT Final F PMA-SMT F Final PMA-
F28914.S596Day2.Plate1.Rep4.SMT.FS596NANANANANANASMT Final F PMA-SMT F Final PMA-
F28914.S597Day2.Plate1.Rep1.SMT.GS597NANANANANANASMT Final G PMA-SMT G Final PMA-
F28914.S598Day2.Plate1.Rep2.SMT.GS598NANANANANANASMT Final G PMA-SMT G Final PMA-
F28914.S599Day2.Plate1.Rep3.SMT.GS599NANANANANANASMT Final G PMA-SMT G Final PMA-
F28914.S600Day2.Plate1.Rep4.SMT.GS600NANANANANANASMT Final G PMA-SMT G Final PMA-
F28914.S601Day2.Plate1.Rep1.SMT.HS601NANANANANANASMT Final H PMA-SMT H Final PMA-
F28914.S602Day2.Plate1.Rep2.SMT.HS602NANANANANANASMT Final H PMA-SMT H Final PMA-
F28914.S603Day2.Plate1.Rep3.SMT.HS603NANANANANANASMT Final H PMA-SMT H Final PMA-
F28914.S604Day2.Plate1.Rep4.SMT.HS604NANANANANANASMT Final H PMA-SMT H Final PMA-
F28914.S605Day2.Plate1.Rep1.SMT.IS605NANANANANANASMT Final I PMA-SMT I Final PMA-
F28914.S606Day2.Plate1.Rep2.SMT.IS606NANANANANANASMT Final I PMA-SMT I Final PMA-
F28914.S607Day2.Plate1.Rep3.SMT.IS607NANANANANANASMT Final I PMA-SMT I Final PMA-
F28914.S608Day2.Plate1.Rep4.SMT.IS608NANANANANANASMT Final I PMA-SMT I Final PMA-
F28914.S609Day2.Plate1.Rep1.SMT.JS609NANANANANANASMT Final J PMA-SMT J Final PMA-
F28914.S610Day2.Plate1.Rep2.SMT.JS610NANANANANANASMT Final J PMA-SMT J Final PMA-
F28914.S611Day2.Plate1.Rep3.SMT.JS611NANANANANANASMT Final J PMA-SMT J Final PMA-
F28914.S612Day2.Plate1.Rep4.SMT.JS612NANANANANANASMT Final J PMA-SMT J Final PMA-
F28914.S613Day2.V.Plt1.Rep1.SMT.AS613NANANANANANASMT Final A PMA+SMT A Final PMA+
F28914.S614Day2.V.Plt1.Rep2.SMT.AS614NANANANANANASMT Final A PMA+SMT A Final PMA+
F28914.S615Day2.V.Plt1.Rep3.SMT.AS615NANANANANANASMT Final A PMA+SMT A Final PMA+
F28914.S616Day2.V.Plt1.Rep4.SMT.AS616NANANANANANASMT Final A PMA+SMT A Final PMA+
F28914.S617Day2.V.Plt2.Rep5.SMT.AS617NANANANANANASMT Final A PMA+SMT A Final PMA+
F28914.S618Day2.V.Plt2.Rep6.SMT.AS618NANANANANANASMT Final A PMA+SMT A Final PMA+
F28914.S619Day2.V.Plt2.Rep7.SMT.AS619NANANANANANASMT Final A PMA+SMT A Final PMA+
F28914.S620Day2.V.Plt2.Rep8.SMT.AS620NANANANANANASMT Final A PMA+SMT A Final PMA+
F28914.S621Day2.V.Plt1.Rep1.SMT.BS621NANANANANANASMT Final B PMA+SMT B Final PMA+
F28914.S622Day2.V.Plt1.Rep2.SMT.BS622NANANANANANASMT Final B PMA+SMT B Final PMA+
F28914.S623Day2.V.Plt1.Rep3.SMT.BS623NANANANANANASMT Final B PMA+SMT B Final PMA+
F28914.S624Day2.V.Plt1.Rep4.SMT.BS624NANANANANANASMT Final B PMA+SMT B Final PMA+
F28914.S625Day2.V.Plt2.Rep5.SMT.BS625NANANANANANASMT Final B PMA+SMT B Final PMA+
F28914.S626Day2.V.Plt2.Rep6.SMT.BS626NANANANANANASMT Final B PMA+SMT B Final PMA+
F28914.S627Day2.V.Plt2.Rep7.SMT.BS627NANANANANANASMT Final B PMA+SMT B Final PMA+
F28914.S628Day2.V.Plt2.Rep8.SMT.BS628NANANANANANASMT Final B PMA+SMT B Final PMA+
F28914.S629Day2.V.Plt1.Rep1.SMT.CS629NANANANANANASMT Final C PMA+SMT C Final PMA+
F28914.S630Day2.V.Plt1.Rep2.SMT.CS630NANANANANANASMT Final C PMA+SMT C Final PMA+
F28914.S631Day2.V.Plt1.Rep3.SMT.CS631NANANANANANASMT Final C PMA+SMT C Final PMA+
F28914.S632Day2.V.Plt1.Rep4.SMT.CS632NANANANANANASMT Final C PMA+SMT C Final PMA+
F28914.S633Day2.V.Plt2.Rep5.SMT.CS633NANANANANANASMT Final C PMA+SMT C Final PMA+
F28914.S634Day2.V.Plt2.Rep6.SMT.CS634NANANANANANASMT Final C PMA+SMT C Final PMA+
F28914.S635Day2.V.Plt2.Rep7.SMT.CS635NANANANANANASMT Final C PMA+SMT C Final PMA+
F28914.S636Day2.V.Plt2.Rep8.SMT.CS636NANANANANANASMT Final C PMA+SMT C Final PMA+
F28914.S637Day2.V.Plt1.Rep1.SMT.DS637NANANANANANASMT Final D PMA+SMT D Final PMA+
F28914.S638Day2.V.Plt1.Rep2.SMT.DS638NANANANANANASMT Final D PMA+SMT D Final PMA+
F28914.S639Day2.V.Plt1.Rep3.SMT.DS639NANANANANANASMT Final D PMA+SMT D Final PMA+
F28914.S640Day2.V.Plt1.Rep4.SMT.DS640NANANANANANASMT Final D PMA+SMT D Final PMA+
F28914.S641Day2.V.Plt2.Rep5.SMT.DS641NANANANANANASMT Final D PMA+SMT D Final PMA+
F28914.S642Day2.V.Plt2.Rep6.SMT.DS642NANANANANANASMT Final D PMA+SMT D Final PMA+
F28914.S643Day2.V.Plt2.Rep7.SMT.DS643NANANANANANASMT Final D PMA+SMT D Final PMA+
F28914.S644Day2.V.Plt2.Rep8.SMT.DS644NANANANANANASMT Final D PMA+SMT D Final PMA+
F28914.S645Day2.V.Plt1.Rep1.SMT.ES645NANANANANANASMT Final E PMA+SMT E Final PMA+
F28914.S646Day2.V.Plt1.Rep2.SMT.ES646NANANANANANASMT Final E PMA+SMT E Final PMA+
F28914.S647Day2.V.Plt1.Rep3.SMT.ES647NANANANANANASMT Final E PMA+SMT E Final PMA+
F28914.S648Day2.V.Plt1.Rep4.SMT.ES648NANANANANANASMT Final E PMA+SMT E Final PMA+
F28914.S649Day2.V.Plt2.Rep5.SMT.ES649NANANANANANASMT Final E PMA+SMT E Final PMA+
F28914.S650Day2.V.Plt2.Rep6.SMT.ES650NANANANANANASMT Final E PMA+SMT E Final PMA+
F28914.S651Day2.V.Plt2.Rep7.SMT.ES651NANANANANANASMT Final E PMA+SMT E Final PMA+
F28914.S652Day2.V.Plt2.Rep8.SMT.ES652NANANANANANASMT Final E PMA+SMT E Final PMA+
F28914.S653Day2.V.Plt1.Rep1.SMT.FS653NANANANANANASMT Final F PMA+SMT F Final PMA+
F28914.S654Day2.V.Plt1.Rep2.SMT.FS654NANANANANANASMT Final F PMA+SMT F Final PMA+
F28914.S655Day2.V.Plt1.Rep3.SMT.FS655NANANANANANASMT Final F PMA+SMT F Final PMA+
F28914.S656Day2.V.Plt1.Rep4.SMT.FS656NANANANANANASMT Final F PMA+SMT F Final PMA+
F28914.S657Day2.V.Plt1.Rep1.SMT.GS657NANANANANANASMT Final G PMA+SMT G Final PMA+
F28914.S658Day2.V.Plt1.Rep2.SMT.GS658NANANANANANASMT Final G PMA+SMT G Final PMA+
F28914.S659Day2.V.Plt1.Rep3.SMT.GS659NANANANANANASMT Final G PMA+SMT G Final PMA+
F28914.S660Day2.V.Plt1.Rep4.SMT.GS660NANANANANANASMT Final G PMA+SMT G Final PMA+
F28914.S661Day2.V.Plt1.Rep1.SMT.HS661NANANANANANASMT Final H PMA+SMT H Final PMA+
F28914.S662Day2.V.Plt1.Rep2.SMT.HS662NANANANANANASMT Final H PMA+SMT H Final PMA+
F28914.S663Day2.V.Plt1.Rep3.SMT.HS663NANANANANANASMT Final H PMA+SMT H Final PMA+
F28914.S664Day2.V.Plt1.Rep4.SMT.HS664NANANANANANASMT Final H PMA+SMT H Final PMA+
F28914.S665Day2.V.Plt1.Rep1.SMT.IS665NANANANANANASMT Final I PMA+SMT I Final PMA+
F28914.S666Day2.V.Plt1.Rep2.SMT.IS666NANANANANANASMT Final I PMA+SMT I Final PMA+
F28914.S667Day2.V.Plt1.Rep3.SMT.IS667NANANANANANASMT Final I PMA+SMT I Final PMA+
F28914.S668Day2.V.Plt1.Rep4.SMT.IS668NANANANANANASMT Final I PMA+SMT I Final PMA+
F28914.S669Day2.V.Plt1.Rep1.SMT.JS669NANANANANANASMT Final J PMA+SMT J Final PMA+
F28914.S670Day2.V.Plt1.Rep2.SMT.JS670NANANANANANASMT Final J PMA+SMT J Final PMA+
F28914.S671Day2.V.Plt1.Rep3.SMT.JS671NANANANANANASMT Final J PMA+SMT J Final PMA+
F28914.S672Day2.V.Plt1.Rep4.SMT.JS672NANANANANANASMT Final J PMA+SMT J Final PMA+
 
 

ASV Read Counts by Samples

#Sample IDRead Count
F28914.S45127,614
F28914.S20330,611
F28914.S49130,681
F28914.S52231,116
F28914.S48933,492
F28914.S43933,951
F28914.S51334,194
F28914.S51434,785
F28914.S52135,036
F28914.S49435,282
F28914.S49635,550
F28914.S25236,007
F28914.S48836,947
F28914.S50137,409
F28914.S49337,425
F28914.S43337,899
F28914.S08037,915
F28914.S46438,177
F28914.S25838,207
F28914.S00438,650
F28914.S52839,515
F28914.S01439,546
F28914.S02539,607
F28914.S43439,672
F28914.S43839,691
F28914.S43639,700
F28914.S49839,775
F28914.S46839,811
F28914.S50040,109
F28914.S48640,410
F28914.S11340,511
F28914.S49541,060
F28914.S12941,112
F28914.S44841,134
F28914.S51941,314
F28914.S19741,322
F28914.S19341,395
F28914.S24941,515
F28914.S43741,757
F28914.S12442,027
F28914.S45842,033
F28914.S30442,351
F28914.S29142,370
F28914.S27542,412
F28914.S19142,550
F28914.S26942,562
F28914.S20042,912
F28914.S43542,993
F28914.S26743,052
F28914.S31543,371
F28914.S19943,432
F28914.S14543,644
F28914.S06643,764
F28914.S25343,976
F28914.S44744,070
F28914.S12144,208
F28914.S49244,260
F28914.S48044,581
F28914.S44244,718
F28914.S51845,028
F28914.S52345,111
F28914.S27745,258
F28914.S01845,352
F28914.S44645,613
F28914.S28445,712
F28914.S40045,717
F28914.S13045,719
F28914.S51145,770
F28914.S45545,855
F28914.S51745,892
F28914.S28245,922
F28914.S19446,000
F28914.S06046,088
F28914.S51646,164
F28914.S34046,242
F28914.S54946,329
F28914.S07846,345
F28914.S26146,486
F28914.S24046,626
F28914.S26246,692
F28914.S33846,698
F28914.S05946,915
F28914.S50246,990
F28914.S28647,016
F28914.S29247,057
F28914.S44547,059
F28914.S14847,071
F28914.S09147,221
F28914.S39347,288
F28914.S02347,445
F28914.S07747,477
F28914.S04747,645
F28914.S26347,707
F28914.S48747,756
F28914.S53847,857
F28914.S15147,899
F28914.S05747,912
F28914.S00147,965
F28914.S39848,007
F28914.S45948,061
F28914.S30148,130
F28914.S46048,177
F28914.S19648,253
F28914.S04848,260
F28914.S28048,405
F28914.S27848,632
F28914.S11448,687
F28914.S47048,729
F28914.S07648,783
F28914.S27948,787
F28914.S41548,958
F28914.S09748,969
F28914.S30349,036
F28914.S27449,104
F28914.S07449,162
F28914.S23749,184
F28914.S47849,197
F28914.S25749,226
F28914.S28749,275
F28914.S07149,385
F28914.S39749,435
F28914.S46149,449
F28914.S39949,578
F28914.S12349,619
F28914.S31849,679
F28914.S09849,722
F28914.S23449,799
F28914.S18649,868
F28914.S49749,937
F28914.S47949,981
F28914.S46950,035
F28914.S14050,117
F28914.S26450,142
F28914.S12850,310
F28914.S07950,328
F28914.S49050,353
F28914.S13450,404
F28914.S09350,435
F28914.S41950,478
F28914.S48250,484
F28914.S45650,493
F28914.S44950,515
F28914.S52050,597
F28914.S33550,607
F28914.S50650,637
F28914.S59550,717
F28914.S13150,744
F28914.S10250,857
F28914.S15350,870
F28914.S40650,913
F28914.S37251,047
F28914.S00551,103
F28914.S12051,105
F28914.S07251,193
F28914.S47251,200
F28914.S45751,208
F28914.S28351,218
F28914.S03051,254
F28914.S01351,299
F28914.S54351,337
F28914.S14451,378
F28914.S01751,386
F28914.S01651,454
F28914.S48151,466
F28914.S25951,506
F28914.S13951,636
F28914.S04251,643
F28914.S46551,679
F28914.S03451,696
F28914.S37751,709
F28914.S47351,769
F28914.S29651,774
F28914.S17151,803
F28914.S60351,856
F28914.S30751,958
F28914.S13651,974
F28914.S03851,974
F28914.S05251,978
F28914.S26552,019
F28914.S32452,061
F28914.S11652,098
F28914.S05552,134
F28914.S52552,155
F28914.S15652,217
F28914.S49952,237
F28914.S04052,385
F28914.S15252,389
F28914.S13852,571
F28914.S25652,599
F28914.S25452,627
F28914.S24652,631
F28914.S22252,654
F28914.S35052,725
F28914.S09552,728
F28914.S46252,736
F28914.S39552,756
F28914.S12552,782
F28914.S48452,805
F28914.S50952,808
F28914.S26052,869
F28914.S47752,877
F28914.S27152,902
F28914.S47452,925
F28914.S12653,004
F28914.S24353,133
F28914.S02853,140
F28914.S15453,205
F28914.S03353,321
F28914.S32253,345
F28914.S45453,367
F28914.S07353,409
F28914.S00653,557
F28914.S03153,568
F28914.S28853,580
F28914.S61553,654
F28914.S01953,702
F28914.S05653,733
F28914.S14653,778
F28914.S23853,876
F28914.S44453,881
F28914.S03253,904
F28914.S44053,921
F28914.S62653,992
F28914.S31054,003
F28914.S37354,044
F28914.S02154,061
F28914.S36554,067
F28914.S11554,074
F28914.S30054,079
F28914.S29354,094
F28914.S41354,296
F28914.S23654,329
F28914.S38554,344
F28914.S02454,355
F28914.S14954,372
F28914.S16054,401
F28914.S52454,442
F28914.S00954,477
F28914.S51254,480
F28914.S30854,498
F28914.S37154,554
F28914.S18554,561
F28914.S08554,571
F28914.S18854,574
F28914.S28154,630
F28914.S11754,718
F28914.S42354,734
F28914.S50855,159
F28914.S03555,200
F28914.S31455,268
F28914.S19855,275
F28914.S21455,296
F28914.S22155,325
F28914.S35455,360
F28914.S06555,376
F28914.S09455,394
F28914.S02755,429
F28914.S41855,535
F28914.S57155,543
F28914.S17955,609
F28914.S51555,647
F28914.S17655,687
F28914.S34955,688
F28914.S32055,710
F28914.S10655,736
F28914.S16855,893
F28914.S56055,986
F28914.S09955,996
F28914.S14156,000
F28914.S30556,005
F28914.S13356,046
F28914.S03656,051
F28914.S20656,100
F28914.S46756,111
F28914.S15056,136
F28914.S23356,268
F28914.S34356,510
F28914.S38656,521
F28914.S20156,568
F28914.S44156,578
F28914.S35856,600
F28914.S23056,628
F28914.S09656,652
F28914.S11256,655
F28914.S54456,675
F28914.S05356,699
F28914.S45256,707
F28914.S14756,710
F28914.S12256,758
F28914.S26656,766
F28914.S47156,817
F28914.S38256,937
F28914.S37456,946
F28914.S13756,966
F28914.S12756,968
F28914.S32356,973
F28914.S11156,973
F28914.S27357,005
F28914.S24857,084
F28914.S64557,094
F28914.S01257,147
F28914.S01557,280
F28914.S02057,316
F28914.S27257,359
F28914.S56457,380
F28914.S14357,436
F28914.S39057,462
F28914.S53657,543
F28914.S13257,600
F28914.S63757,610
F28914.S23957,725
F28914.S35757,791
F28914.S21557,794
F28914.S55757,836
F28914.S54257,938
F28914.S62358,002
F28914.S27058,069
F28914.S10158,161
F28914.S39658,216
F28914.S08358,241
F28914.S66458,438
F28914.S10958,452
F28914.S22358,458
F28914.S20958,477
F28914.S10458,486
F28914.S44358,509
F28914.S66858,524
F28914.S26858,528
F28914.S38958,540
F28914.S29058,567
F28914.S15958,596
F28914.S50558,615
F28914.S11958,615
F28914.S56358,651
F28914.S36058,751
F28914.S01058,783
F28914.S08958,787
F28914.S24158,813
F28914.S30258,871
F28914.S11058,893
F28914.S36358,949
F28914.S18758,955
F28914.S20458,990
F28914.S09059,009
F28914.S05859,046
F28914.S21859,066
F28914.S40559,156
F28914.S32159,217
F28914.S27659,232
F28914.S65859,284
F28914.S62259,305
F28914.S33959,390
F28914.S28559,396
F28914.S10059,396
F28914.S42059,412
F28914.S39159,493
F28914.S20559,513
F28914.S03759,547
F28914.S53559,604
F28914.S29759,660
F28914.S24559,951
F28914.S39459,995
F28914.S06160,002
F28914.S53760,019
F28914.S25560,053
F28914.S55160,067
F28914.S36960,084
F28914.S59660,087
F28914.S60460,133
F28914.S46660,210
F28914.S32960,352
F28914.S13560,375
F28914.S02260,431
F28914.S38460,467
F28914.S47660,498
F28914.S41260,500
F28914.S11860,533
F28914.S16260,538
F28914.S51060,712
F28914.S54160,720
F28914.S31660,760
F28914.S62460,807
F28914.S08760,894
F28914.S35560,902
F28914.S03960,922
F28914.S19260,977
F28914.S10561,001
F28914.S15561,007
F28914.S64261,049
F28914.S42161,071
F28914.S22961,076
F28914.S09261,094
F28914.S66961,136
F28914.S35661,321
F28914.S16161,356
F28914.S34661,369
F28914.S18961,391
F28914.S05161,436
F28914.S55861,498
F28914.S06461,527
F28914.S17461,535
F28914.S16961,550
F28914.S40461,576
F28914.S53461,586
F28914.S19061,591
F28914.S18361,604
F28914.S36861,684
F28914.S00761,688
F28914.S10761,701
F28914.S33361,711
F28914.S23561,731
F28914.S00861,776
F28914.S65361,903
F28914.S37661,906
F28914.S66762,013
F28914.S59062,036
F28914.S32762,080
F28914.S58462,139
F28914.S22762,185
F28914.S38362,213
F28914.S24762,247
F28914.S35962,314
F28914.S15862,381
F28914.S39262,402
F28914.S21962,436
F28914.S04362,457
F28914.S38062,465
F28914.S46362,479
F28914.S34262,536
F28914.S45362,592
F28914.S08162,712
F28914.S02962,741
F28914.S25162,773
F28914.S59862,793
F28914.S36762,851
F28914.S55962,936
F28914.S53962,941
F28914.S57263,094
F28914.S19563,095
F28914.S56263,199
F28914.S10363,211
F28914.S61963,224
F28914.S67263,356
F28914.S33463,381
F28914.S66163,448
F28914.S14263,453
F28914.S38763,492
F28914.S17563,516
F28914.S66063,563
F28914.S55563,595
F28914.S53163,604
F28914.S22463,707
F28914.S08863,731
F28914.S35363,774
F28914.S31763,992
F28914.S10864,057
F28914.S56664,061
F28914.S34764,075
F28914.S43164,228
F28914.S06364,233
F28914.S55264,313
F28914.S35264,474
F28914.S66264,522
F28914.S63564,538
F28914.S04964,554
F28914.S65464,862
F28914.S02664,886
F28914.S66364,915
F28914.S63064,963
F28914.S25064,966
F28914.S37565,084
F28914.S35165,095
F28914.S22665,144
F28914.S48365,198
F28914.S41065,276
F28914.S36665,536
F28914.S21165,607
F28914.S08465,650
F28914.S21765,844
F28914.S61365,873
F28914.S54765,889
F28914.S61865,944
F28914.S33765,962
F28914.S65566,193
F28914.S37866,242
F28914.S15766,250
F28914.S62966,289
F28914.S54666,384
F28914.S61466,441
F28914.S62166,490
F28914.S41766,540
F28914.S62566,637
F28914.S40866,638
F28914.S54566,706
F28914.S40766,765
F28914.S04466,876
F28914.S40366,902
F28914.S01166,921
F28914.S48566,940
F28914.S21067,017
F28914.S64867,167
F28914.S30967,255
F28914.S53367,357
F28914.S17267,387
F28914.S16667,401
F28914.S17067,518
F28914.S64167,549
F28914.S54867,611
F28914.S56167,662
F28914.S36267,923
F28914.S05467,957
F28914.S08668,019
F28914.S24268,053
F28914.S23168,056
F28914.S29568,072
F28914.S34168,126
F28914.S42868,134
F28914.S67068,190
F28914.S42468,212
F28914.S45068,287
F28914.S63368,311
F28914.S34468,332
F28914.S50368,353
F28914.S42668,408
F28914.S04168,436
F28914.S58168,527
F28914.S34568,544
F28914.S55468,582
F28914.S59468,608
F28914.S32868,637
F28914.S07568,746
F28914.S16368,813
F28914.S21368,919
F28914.S37969,192
F28914.S36169,325
F28914.S38869,422
F28914.S52769,464
F28914.S66569,614
F28914.S38169,702
F28914.S40969,732
F28914.S33169,769
F28914.S24469,785
F28914.S65769,787
F28914.S64069,996
F28914.S28970,218
F28914.S33670,245
F28914.S42770,264
F28914.S00370,336
F28914.S66670,359
F28914.S57970,366
F28914.S47570,478
F28914.S37070,540
F28914.S23270,559
F28914.S67170,630
F28914.S42970,766
F28914.S58070,777
F28914.S50770,848
F28914.S55070,859
F28914.S52970,863
F28914.S53270,932
F28914.S60970,960
F28914.S17371,013
F28914.S63471,245
F28914.S61771,280
F28914.S40271,306
F28914.S17771,356
F28914.S07071,417
F28914.S63271,728
F28914.S29471,805
F28914.S62071,841
F28914.S60271,876
F28914.S36471,945
F28914.S41472,080
F28914.S04672,205
F28914.S16472,271
F28914.S60072,407
F28914.S41172,673
F28914.S63172,687
F28914.S55672,869
F28914.S33072,897
F28914.S34873,105
F28914.S63873,317
F28914.S31973,430
F28914.S65973,491
F28914.S18273,595
F28914.S42273,949
F28914.S61173,968
F28914.S08274,043
F28914.S00274,073
F28914.S58274,214
F28914.S22874,231
F28914.S56774,302
F28914.S62874,684
F28914.S16774,751
F28914.S65074,882
F28914.S22575,169
F28914.S16575,188
F28914.S60775,238
F28914.S32575,270
F28914.S58375,304
F28914.S57675,752
F28914.S52676,078
F28914.S21676,185
F28914.S56576,194
F28914.S42576,322
F28914.S18476,593
F28914.S31176,704
F28914.S20277,058
F28914.S64477,106
F28914.S20877,299
F28914.S56877,528
F28914.S57077,687
F28914.S43077,706
F28914.S40177,826
F28914.S60877,836
F28914.S58878,297
F28914.S22078,299
F28914.S64978,345
F28914.S60579,023
F28914.S33279,108
F28914.S63679,365
F28914.S53079,434
F28914.S20779,509
F28914.S05079,536
F28914.S57779,553
F28914.S41679,626
F28914.S57380,104
F28914.S32680,123
F28914.S30680,298
F28914.S18080,334
F28914.S43281,008
F28914.S63981,053
F28914.S59381,324
F28914.S65682,187
F28914.S21282,268
F28914.S04582,279
F28914.S58782,622
F28914.S54082,759
F28914.S59983,166
F28914.S57583,174
F28914.S17883,889
F28914.S61684,445
F28914.S59784,687
F28914.S60184,859
F28914.S62785,042
F28914.S31285,230
F28914.S58585,874
F28914.S58986,612
F28914.S55387,880
F28914.S18188,134
F28914.S64388,351
F28914.S61088,780
F28914.S06789,101
F28914.S61289,700
F28914.S50490,838
F28914.S56990,887
F28914.S64793,672
F28914.S06994,430
F28914.S06895,116
F28914.S65295,344
F28914.S06299,621
F28914.S578100,347
F28914.S651100,970
F28914.S313102,626
F28914.S574104,854
F28914.S592107,963
F28914.S606109,985
F28914.S591114,855
F28914.S646117,143
F28914.S586123,982
 
 
 

VII. Analysis - Read Taxonomy Assignment

Read Taxonomy Assignment - Methods

 

The close-reference taxonomy assignment of the ASV sequences using BLASTN is based on the algorithm published by Al-Hebshi et. al. (2015)[2].

The species-level, open-reference 16S rRNA NGS reads taxonomy assignment pipeline

Version 20210310a
 
 

1. Raw sequences reads in FASTA format were BLASTN-searched against a combined set of 16S rRNA reference sequences - the FOMC 16S rRNA Reference Sequences version 20221029 (https://microbiome.forsyth.org/ftp/refseq/). This set consists of the HOMD (version 15.22 http://www.homd.org/index.php?name=seqDownload&file&type=R ), Mouse Oral Microbiome Database (MOMD version 5.1 https://momd.org/ftp/16S_rRNA_refseq/MOMD_16S_rRNA_RefSeq/V5.1/), and the NCBI 16S rRNA reference sequence set (https://ftp.ncbi.nlm.nih.gov/blast/db/16S_ribosomal_RNA.tar.gz). These sequences were screened and combined to remove short sequences (<1000nt), chimera, duplicated and sub-sequences, as well as sequences with poor taxonomy annotation (e.g., without species information). This process resulted in 1,015 full-length 16S rRNA sequences from HOMD V15.22, 356 from MOMD V5.1, and 22,126 from NCBI, a total of 23,497 sequences. Altogether these sequence represent a total of 17,035 oral and non-oral microbial species.

The NCBI BLASTN version 2.7.1+ (Zhang et al, 2000) [3] was used with the default parameters. Reads with ≥ 98% sequence identity to the matched reference and ≥ 90% alignment length (i.e., ≥ 90% of the read length that was aligned to the reference and was used to calculate the sequence percent identity) were classified based on the taxonomy of the reference sequence with highest sequence identity. If a read matched with reference sequences representing more than one species with equal percent identity and alignment length, it was subject to chimera checking with USEARCH program version v8.1.1861 (Edgar 2010). Non-chimeric reads with multi-species best hits were considered valid and were assigned with a unique species notation (e.g., spp) denoting unresolvable multiple species.

2. Unassigned reads (i.e., reads with < 98% identity or < 90% alignment length) were pooled together and reads < 200 bases were removed. The remaining reads were subject to the de novo operational taxonomy unit (OTU) calling and chimera checking using the USEARCH program version v8.1.1861 (Edgar 2010)[4]. The de novo OTU calling and chimera checking was done using 98% as the sequence identity cutoff, i.e., the species-level OTU. The output of this step produced species-level de novo clustered OTUs with 98% identity. Representative reads from each of the OTUs/species were then BLASTN-searched against the same reference sequence set again to determine the closest species for these potential novel species. These potential novel species were pooled together with the reads that were signed to specie-level in the previous step, for down-stream analyses.

Reference:

  1. Al-Hebshi NN, Nasher AT, Idris AM, Chen T. Robust species taxonomy assignment algorithm for 16S rRNA NGS reads: application to oral carcinoma samples. J Oral Microbiol. 2015 Sep 29;7:28934. doi: 10.3402/jom.v7.28934. PMID: 26426306; PMCID: PMC4590409.
  2. Zhang Z, Schwartz S, Wagner L, Miller W. A greedy algorithm for aligning DNA sequences. J Comput Biol. 2000 Feb-Apr;7(1-2):203-14. doi: 10.1089/10665270050081478. PMID: 10890397.
  3. Edgar RC. Search and clustering orders of magnitude faster than BLAST. Bioinformatics. 2010 Oct 1;26(19):2460-1. doi: 10.1093/bioinformatics/btq461. Epub 2010 Aug 12. PubMed PMID: 20709691.

    4. 3. Designations used in the taxonomy:

    	1) Taxonomy levels are indicated by these prefixes:
	
	   k__: domain/kingdom
	   p__: phylum
	   c__: class
	   o__: order
	   f__: family
	   g__: genus  
	   s__: species
	
	   Example: 
	
	   k__Bacteria;p__Firmicutes;c__Clostridia;o__Clostridiales;f__Lachnospiraceae;g__Blautia;s__faecis
		
	2) Unique level identified – known species:
	   
	   k__Bacteria;p__Firmicutes;c__Clostridia;o__Clostridiales;f__Lachnospiraceae;g__Roseburia;s__hominis
	
	   The above example shows some reads match to a single species (all levels are unique)
	
	3) Non-unique level identified – known species:

	   k__Bacteria;p__Firmicutes;c__Clostridia;o__Clostridiales;f__Lachnospiraceae;g__Roseburia;s__multispecies_spp123_3
	   
	   The above example “s__multispecies_spp123_3” indicates certain reads equally match to 3 species of the 
	   genus Roseburia; the “spp123” is a temporally assigned species ID.
	
	   k__Bacteria;p__Firmicutes;c__Clostridia;o__Clostridiales;f__Lachnospiraceae;g__multigenus;s__multispecies_spp234_5
	   
	   The above example indicates certain reads match equally to 5 different species, which belong to multiple genera.; 
	   the “spp234” is a temporally assigned species ID.
	
	4) Unique level identified – unknown species, potential novel species:
	   
	   k__Bacteria;p__Firmicutes;c__Clostridia;o__Clostridiales;f__Lachnospiraceae;g__Roseburia;s__ hominis_nov_97%
	   
	   The above example indicates that some reads have no match to any of the reference sequences with 
	   sequence identity ≥ 98% and percent coverage (alignment length)  ≥ 98% as well. However this groups 
	   of reads (actually the representative read from a de novo  OTU) has 96% percent identity to 
	   Roseburia hominis, thus this is a potential novel species, closest to Roseburia hominis. 
	   (But they are not the same species).
	
	5) Multiple level identified – unknown species, potential novel species:
	   k__Bacteria;p__Firmicutes;c__Clostridia;o__Clostridiales;f__Lachnospiraceae;g__Roseburia;s__ multispecies_sppn123_3_nov_96%
	
	   The above example indicates that some reads have no match to any of the reference sequences 
	   with sequence identity ≥ 98% and percent coverage (alignment length)  ≥ 98% as well. 
	   However this groups of reads (actually the representative read from a de novo  OTU) 
	   has 96% percent identity equally to 3 species in Roseburia. Thus this is no single 
	   closest species, instead this group of reads match equally to multiple species at 96%. 
	   Since they have passed chimera check so they represent a novel species. “sppn123” is a 
	   temporary ID for this potential novel species.

 
4. The taxonomy assignment algorithm is illustrated in this flow char below:
 
 
 
 

Read Taxonomy Assignment - Result Summary *

CodeCategoryMPC=0% (>=1 read)MPC=0.01%(>=4021 reads)
ATotal reads40,264,14940,264,149
BTotal assigned reads40,218,97740,218,977
CAssigned reads in species with read count < MPC0283,287
DAssigned reads in samples with read count < 50000
ETotal samples670670
FSamples with reads >= 500670670
GSamples with reads < 50000
HTotal assigned reads used for analysis (B-C-D)40,218,97739,935,690
IReads assigned to single species35,763,45935,546,808
JReads assigned to multiple species4,004,5543,982,901
KReads assigned to novel species450,964405,981
LTotal number of species1,153146
MNumber of single species615122
NNumber of multi-species5312
ONumber of novel species48512
PTotal unassigned reads45,17245,172
QChimeric reads634634
RReads without BLASTN hits23,15823,158
SOthers: short, low quality, singletons, etc.21,38021,380
A=B+P=C+D+H+Q+R+S
E=F+G
B=C+D+H
H=I+J+K
L=M+N+O
P=Q+R+S
* MPC = Minimal percent (of all assigned reads) read count per species, species with read count < MPC were removed.
* Samples with reads < 500 were removed from downstream analyses.
* The assignment result from MPC=0.1% was used in the downstream analyses.
 
 
 

Read Taxonomy Assignment - ASV Species-Level Read Counts Table

This table shows the read counts for each sample (columns) and each species identified based on the ASV sequences. The downstream analyses were based on this table.
SPIDTaxonomyF28914.S001F28914.S002F28914.S003F28914.S004F28914.S005F28914.S006F28914.S007F28914.S008F28914.S009F28914.S010F28914.S011F28914.S012F28914.S013F28914.S014F28914.S015F28914.S016F28914.S017F28914.S018F28914.S019F28914.S020F28914.S021F28914.S022F28914.S023F28914.S024F28914.S025F28914.S026F28914.S027F28914.S028F28914.S029F28914.S030F28914.S031F28914.S032F28914.S033F28914.S034F28914.S035F28914.S036F28914.S037F28914.S038F28914.S039F28914.S040F28914.S041F28914.S042F28914.S043F28914.S044F28914.S045F28914.S046F28914.S047F28914.S048F28914.S049F28914.S050F28914.S051F28914.S052F28914.S053F28914.S054F28914.S055F28914.S056F28914.S057F28914.S058F28914.S059F28914.S060F28914.S061F28914.S062F28914.S063F28914.S064F28914.S065F28914.S066F28914.S067F28914.S068F28914.S069F28914.S070F28914.S071F28914.S072F28914.S073F28914.S074F28914.S075F28914.S076F28914.S077F28914.S078F28914.S079F28914.S080F28914.S081F28914.S082F28914.S083F28914.S084F28914.S085F28914.S086F28914.S087F28914.S088F28914.S089F28914.S090F28914.S091F28914.S092F28914.S093F28914.S094F28914.S095F28914.S096F28914.S097F28914.S098F28914.S099F28914.S100F28914.S101F28914.S102F28914.S103F28914.S104F28914.S105F28914.S106F28914.S107F28914.S108F28914.S109F28914.S110F28914.S111F28914.S112F28914.S113F28914.S114F28914.S115F28914.S116F28914.S117F28914.S118F28914.S119F28914.S120F28914.S121F28914.S122F28914.S123F28914.S124F28914.S125F28914.S126F28914.S127F28914.S128F28914.S129F28914.S130F28914.S131F28914.S132F28914.S133F28914.S134F28914.S135F28914.S136F28914.S137F28914.S138F28914.S139F28914.S140F28914.S141F28914.S142F28914.S143F28914.S144F28914.S145F28914.S146F28914.S147F28914.S148F28914.S149F28914.S150F28914.S151F28914.S152F28914.S153F28914.S154F28914.S155F28914.S156F28914.S157F28914.S158F28914.S159F28914.S160F28914.S161F28914.S162F28914.S163F28914.S164F28914.S165F28914.S166F28914.S167F28914.S168F28914.S169F28914.S170F28914.S171F28914.S172F28914.S173F28914.S174F28914.S175F28914.S176F28914.S177F28914.S178F28914.S179F28914.S180F28914.S181F28914.S182F28914.S183F28914.S184F28914.S185F28914.S186F28914.S187F28914.S188F28914.S189F28914.S190F28914.S191F28914.S192F28914.S193F28914.S194F28914.S195F28914.S196F28914.S197F28914.S198F28914.S199F28914.S200F28914.S201F28914.S202F28914.S203F28914.S204F28914.S205F28914.S206F28914.S207F28914.S208F28914.S209F28914.S210F28914.S211F28914.S212F28914.S213F28914.S214F28914.S215F28914.S216F28914.S217F28914.S218F28914.S219F28914.S220F28914.S221F28914.S222F28914.S223F28914.S224F28914.S225F28914.S226F28914.S227F28914.S228F28914.S229F28914.S230F28914.S231F28914.S232F28914.S233F28914.S234F28914.S235F28914.S236F28914.S237F28914.S238F28914.S239F28914.S240F28914.S241F28914.S242F28914.S243F28914.S244F28914.S245F28914.S246F28914.S247F28914.S248F28914.S249F28914.S250F28914.S251F28914.S252F28914.S253F28914.S254F28914.S255F28914.S256F28914.S257F28914.S258F28914.S259F28914.S260F28914.S261F28914.S262F28914.S263F28914.S264F28914.S265F28914.S266F28914.S267F28914.S268F28914.S269F28914.S270F28914.S271F28914.S272F28914.S273F28914.S274F28914.S275F28914.S276F28914.S277F28914.S278F28914.S279F28914.S280F28914.S281F28914.S282F28914.S283F28914.S284F28914.S285F28914.S286F28914.S287F28914.S288F28914.S289F28914.S290F28914.S291F28914.S292F28914.S293F28914.S294F28914.S295F28914.S296F28914.S297F28914.S300F28914.S301F28914.S302F28914.S303F28914.S304F28914.S305F28914.S306F28914.S307F28914.S308F28914.S309F28914.S310F28914.S311F28914.S312F28914.S313F28914.S314F28914.S315F28914.S316F28914.S317F28914.S318F28914.S319F28914.S320F28914.S321F28914.S322F28914.S323F28914.S324F28914.S325F28914.S326F28914.S327F28914.S328F28914.S329F28914.S330F28914.S331F28914.S332F28914.S333F28914.S334F28914.S335F28914.S336F28914.S337F28914.S338F28914.S339F28914.S340F28914.S341F28914.S342F28914.S343F28914.S344F28914.S345F28914.S346F28914.S347F28914.S348F28914.S349F28914.S350F28914.S351F28914.S352F28914.S353F28914.S354F28914.S355F28914.S356F28914.S357F28914.S358F28914.S359F28914.S360F28914.S361F28914.S362F28914.S363F28914.S364F28914.S365F28914.S366F28914.S367F28914.S368F28914.S369F28914.S370F28914.S371F28914.S372F28914.S373F28914.S374F28914.S375F28914.S376F28914.S377F28914.S378F28914.S379F28914.S380F28914.S381F28914.S382F28914.S383F28914.S384F28914.S385F28914.S386F28914.S387F28914.S388F28914.S389F28914.S390F28914.S391F28914.S392F28914.S393F28914.S394F28914.S395F28914.S396F28914.S397F28914.S398F28914.S399F28914.S400F28914.S401F28914.S402F28914.S403F28914.S404F28914.S405F28914.S406F28914.S407F28914.S408F28914.S409F28914.S410F28914.S411F28914.S412F28914.S413F28914.S414F28914.S415F28914.S416F28914.S417F28914.S418F28914.S419F28914.S420F28914.S421F28914.S422F28914.S423F28914.S424F28914.S425F28914.S426F28914.S427F28914.S428F28914.S429F28914.S430F28914.S431F28914.S432F28914.S433F28914.S434F28914.S435F28914.S436F28914.S437F28914.S438F28914.S439F28914.S440F28914.S441F28914.S442F28914.S443F28914.S444F28914.S445F28914.S446F28914.S447F28914.S448F28914.S449F28914.S450F28914.S451F28914.S452F28914.S453F28914.S454F28914.S455F28914.S456F28914.S457F28914.S458F28914.S459F28914.S460F28914.S461F28914.S462F28914.S463F28914.S464F28914.S465F28914.S466F28914.S467F28914.S468F28914.S469F28914.S470F28914.S471F28914.S472F28914.S473F28914.S474F28914.S475F28914.S476F28914.S477F28914.S478F28914.S479F28914.S480F28914.S481F28914.S482F28914.S483F28914.S484F28914.S485F28914.S486F28914.S487F28914.S488F28914.S489F28914.S490F28914.S491F28914.S492F28914.S493F28914.S494F28914.S495F28914.S496F28914.S497F28914.S498F28914.S499F28914.S500F28914.S501F28914.S502F28914.S503F28914.S504F28914.S505F28914.S506F28914.S507F28914.S508F28914.S509F28914.S510F28914.S511F28914.S512F28914.S513F28914.S514F28914.S515F28914.S516F28914.S517F28914.S518F28914.S519F28914.S520F28914.S521F28914.S522F28914.S523F28914.S524F28914.S525F28914.S526F28914.S527F28914.S528F28914.S529F28914.S530F28914.S531F28914.S532F28914.S533F28914.S534F28914.S535F28914.S536F28914.S537F28914.S538F28914.S539F28914.S540F28914.S541F28914.S542F28914.S543F28914.S544F28914.S545F28914.S546F28914.S547F28914.S548F28914.S549F28914.S550F28914.S551F28914.S552F28914.S553F28914.S554F28914.S555F28914.S556F28914.S557F28914.S558F28914.S559F28914.S560F28914.S561F28914.S562F28914.S563F28914.S564F28914.S565F28914.S566F28914.S567F28914.S568F28914.S569F28914.S570F28914.S571F28914.S572F28914.S573F28914.S574F28914.S575F28914.S576F28914.S577F28914.S578F28914.S579F28914.S580F28914.S581F28914.S582F28914.S583F28914.S584F28914.S585F28914.S586F28914.S587F28914.S588F28914.S589F28914.S590F28914.S591F28914.S592F28914.S593F28914.S594F28914.S595F28914.S596F28914.S597F28914.S598F28914.S599F28914.S600F28914.S601F28914.S602F28914.S603F28914.S604F28914.S605F28914.S606F28914.S607F28914.S608F28914.S609F28914.S610F28914.S611F28914.S612F28914.S613F28914.S614F28914.S615F28914.S616F28914.S617F28914.S618F28914.S619F28914.S620F28914.S621F28914.S622F28914.S623F28914.S624F28914.S625F28914.S626F28914.S627F28914.S628F28914.S629F28914.S630F28914.S631F28914.S632F28914.S633F28914.S634F28914.S635F28914.S636F28914.S637F28914.S638F28914.S639F28914.S640F28914.S641F28914.S642F28914.S643F28914.S644F28914.S645F28914.S646F28914.S647F28914.S648F28914.S649F28914.S650F28914.S651F28914.S652F28914.S653F28914.S654F28914.S655F28914.S656F28914.S657F28914.S658F28914.S659F28914.S660F28914.S661F28914.S662F28914.S663F28914.S664F28914.S665F28914.S666F28914.S667F28914.S668F28914.S669F28914.S670F28914.S671F28914.S672
SP103Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;sp. HMT0572836481940402214131422339260383137142214202627183002316190000000009000000009583521652000000111901050000000453639362314464926630129701217467274232454725341948042674440112692451774753627177352448694532483020080738282102100326128313549105679495474089461511004770285767526078000000000000000000000000000000936700000030000000000000103000000001000000000000000000038243753424300115308977866172800004535530244641482854877415061666800762901630018230546525871698342740046970617695394495347372937000000000000000000000000000000000000000000000000000000000000000140000000000000000000030160200000000000000000000000360000000026162402524241500000000000022372113300000037000000014310000000000000000000000000000000000000000000000040000000000000000000000000000000000222929035130000000100000000003500000160000000000000040000000000000000000000000000000000000000000000000000000000000000000000000
SP104Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Eikenella;corrodens3157821953697113858696078283672182224242025402432340643418353777505249386332191193103203191136199226136129167262212150146461667472669449606221923201901829222935022022122812747637537332515113959487515271263853808937644632140210142349117413641490177751295656196071376169174289111511412146996012421286960746103912681506930114289112607829391044812101812361343988818149854182510971484173015266918149491128106912571550129583010936179081207223815539927911214928739139511581333130653110523539518218543134801101930202538884168665919728011042041162427625135414006663123210567845401692173293582991455013201771511671370203825117752222313824243701719722433760250482654288931809155312631045119991764684310581042251321221312367930740157383838137578158243331422031233322533932935748678753091823281840381011941208100312285981250982850179632399446145282127306637664841681131750641818248137351125724050613455018574285136527149004391963273551844016130640266577583419354625554711285214201010284669476560113141127299278465549619286274793370524000246411101105319233363601393000242037309776930013416227996670000000014214094484124343163902951662769577717141705454496144694803673535330000000050800003500000000124388067024000287291458246000000000000000000000000000000002692123352461481471642750000000000000000000000000000000084079065869383986078453300000000000030001201027237991260151007510043910539169267020903412400035406450120552309418575530343396000000000000000000000001103390000300468493555409000067000000089160
SP106Bacteria;Proteobacteria;Betaproteobacteria;Burkholderiales;Burkholderiaceae;Lautropia;mirabilis9518019692128112186278154132253164110928710313990399200171216168123323251714528936632516652992314141816101398016512868431065235224711521217315211793067621104104006020356232972410461002937567137151212704666094140504460257327138151145510201281394139613128115959123060441622002531000000008161022000000000000600006086500600010000003018050500054400000000065202020000023012000155140102441012930374722313409000623200003110030379330001825473567102800771951226903416000033060000260000112925611012000000000000000100046068260030000000500020150002460040006518004200000000000002018580007650000171404324669353000053000200000000067001003760000020109710387000000060000000000000000000000000000000000620070200000000000000000000000000000000000014360000000006000002044729631940000000065800000083009000090400006070000000000000000000000000040000900140600000000000000000
SP107Bacteria;Firmicutes;Negativicutes;Veillonellales;Veillonellaceae;Veillonella;tobetsuensis29060345729833536031238426428032329928417026722422221626825527223624727676152135129191140891131229813290383346362358406285127851291151247812620811411110313113990188162179135430587424361296223178204127133120751271251872122963302941847019510818311627926123214016911417715016117315913626422819732635942639110016818722726926728515217326831025226720139727618516210510698951291062121913392812842264032891721891471771551001729522130534628033733624534815122151752345939000000050100458051292793288002354414981474403833850711745216222531178291228070000001611374001200030070000010601276250135106183140172117156109991761021741481132121417381165709064147911071191281661311301551288814858781261511551151091119310572738076398457787911757581071096666471186583547447566633144177806579114851423115141691112170000081000688134302823000800016672835610621648101016126133431000001240000600027000000000000000050001535858000000003248391418553861906155117162274364407153069534540345778303214586800000000513613131710301000000000358242429413312000024141000000000000000000000000000000000131819136713500000000000000000000000000000000411978604232775000000000904140007173359163207334203143630000121170138665669005029578470000897916391210111215732200000000000000000000000001000002300147880000000000000000
SP109Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Schaalia;sp. HMT1801292341961241371395050188447019216217922114512713613517315114516383922171810000503927150020000000555248392547900000396054421517000000111319432136172189866108561169676546741554294756355756543429293478811089664587860173403602132505157604640626810744493948465321297054603672407674394840425366535000000001500000000000024352607940000000000100000000000000000000014201800000800000000260000063544855666245421251034913913812412612649959445647610060605570837373664611910011210910311511413644580500392653108101521361091101311604030406513787770569967105951096876961599359118000600000000000002025351413191400000000000012000000000000000000000000000000000000000000021000134242240000002160000000015011049095320005000028272445523312300050000120000001100000000000000000000018000000000000000000000000000000000002450150000000000000000000000000000000000118678782101979381023000034330000690090121755789570939000006036781131030015461500220831905500710340000080000000000000000000000004500000001503600000000000000000
SP111Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Aggregatibacter;segnis527744212534146170511061095170140146299181624272355463513378964005657155445911452759594441572655933520104313092235151319399301783191832222332313724575355335252461923051632064232107686562735214574631101522381302282191801044877721612172011088221416057163190220158172186345123222163265162244125167211211258310295113317403438295171320265197206191252299126126211202218196516540158233305239246150146198112107961822612916513223282522912971863142583226315505783970006131317100274523000160907710440369102362900111225611153973489949724446039033607914947226400746223016013017027500002193951925020711796264698171126910465942486349194857815064148511014011963177113523535501171071282878112656811413213811652383297423273121483620541191021165953871282040392710413138271082904519197135472267336151242129521222000011693045421392574354015008240670000521243319087372286529338162106845208000175618860006000360000000000140000014200021725920600000000864132971680159020828011140100000106308290138264190198200000000434162101411493600005500942015644321210406339510298000000000000000037600000000017000000213469821360924667616537000000081000000025000003050000313042100377463902091941841900000000000300000171890120800800000031171148154084708070730628991509989611028697487519551000000000000000000000000277700000056812855141958800000000021002411300
SP112Bacteria;Proteobacteria;Gammaproteobacteria;Pseudomonadales;Moraxellaceae;Acinetobacter;junii0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001800400010000000000000000000900000000000002620143200000004000000511000000002600000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000600000011000000000000000000000000000000000000004000600000000000000000070000000000000000000000000000000000000000000000000000000000000000000000000000311000000080200000068850000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP120Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;melaninogenica41957267609733294373404245864500381640834529348972645159803572616959572867547166713178756186719710628832827935024818225639917520188543494388441575375792101012281196108478418243121230714024214980224121149636208726854934503571169103911237684803754232222490126787293742131237430387445241199389826114781931361261671771571363472914493302045769154946955428553714106099276716909278277247315164140167297120139167160383340351471588217515770276166102147200177375053891330233425394578482100000000014657315230611503840025049244000000002039648164294972631122592780000000496014000004004000010519400023902583913433853966153965100270691019265216201129231227176812291714021231911161212104421387381335013101000090006000002000003060030183263109227274015992000003010001014020202014000170060000012204436614153601991700000003400000000000000000000000000005432641444000000400000000000002818856000000000189795689668156492840836000000000000000170000000000000700000033835254950000000000000000000000000000000016271463098814455011261100000000010000000000000000000001113007632615826991642623823720000000000000000687637205524047200000043653791289200460300012620509514103212224206182373415585310000000000000000000000005800000000243313155104000000000306001281451
SP123Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Oribacterium;sinus39371662633541648027415130129029325258942666162960345316023029219016520500000000000026362435363200000000000000000047644831332400000000000020000000000000004000000000000400000026000000020000000000000003000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000220030000000000000000000000000000000000000000200000000000000000000200000000000000000000000000000000000000000000000000000000000000000000000000000000000000000180000000000000000001707001653200000300000470972300000000960030002000000000100000000000000000000000000000000000000000000000000000000000000000000000000000000000000372726110110180000000003000136527222504323411000000004185000000006070067000000000000000000000000000000000000000000000000000000000000000
SP126Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Alloprevotella;sp. HMT91445079351134638441240338223834736924916817116611115510315718814818814514700000000000070415247832320263012025000000000002017000090010000000000000000000000000000000400000000000065000000000000000000000000000000000000000000000000000000000000000000000000000000200000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021632300000000000000000000000000000000000000000000000000000002000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000300000000000000000004004000000000000000000000000000000000000000000000000000000
SP127Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Fusobacteriaceae;Fusobacterium;hwasookii8714215459558410086617772126385963373721744382730314841343297000000054363385043000000201016042669300142300052113427000373300014000158134340001509340390320439497380521236433321102120014733215665698016617034005670139229138480063225717439165211300101145121810949504413910118100084000004895160000009000000000064200000706000000000734640001000000000000000000310000000014000002843424802401200363400000600000008180000029015100010260003700000000000000000000000012000000000000000000000000000000000000000000003000000000000000000000000000000000000000000000000947015200000000000000000000000000000000681311443961176125870000000032000000043000000000200027000000045681630000000000000000000000000000000036951005566106691123000000000000000000000000000000002208694744621991761610000000000000000000000060000000094129136400024000004100913203214901654370129108191000000000000000000000000650000000112623032000000000220003700
SP130Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Fusobacteriaceae;Fusobacterium;periodonticum2718330838381614295831163104198140813602355836162389182630042727258125411932221825192499163820455001145107511941896776223067808213119710721268128417571077103861116311846426067254940413938025611373277544818525215452863574174531639752441383302343411165161629668123611279951966149315871528083741683210196692812321989212279344798167288561095164911481325146215622378243114156910593395168029422232255814311938341838088281328230315641370277132442329555135399212581925165917122145460546115510073327410619285047138045255720502051235213443475695910830172310630886831171344036400000000100301366611812107150640899102533871831130604301231455614020835310047898831133831522353214433165001079361450267005968526022293030601482464108146113344242214827329620992100457615649685961190228923710099646437911855213543457713462039130713121816254319831033100812831077202838533732320012173366301138606179648081111913145763378710136539722299410119605884971723519481359348220293240620342361379142765440682163114477869758152447951628110944170300016320902250333394839375870108008998715724220034617630497583162279221198277102280000009010200922003901940030940200040000000266232383932000005100014304000000016535337229451181471472945261118753993335734383179305941424215000000501761020000021000000300110011044159042000009942061246700000081800000000000000000000000010132014224036441885120136043252000000037000000017000000000000090091421950952687176471735481925752120270000020018030084692153816640545606102928212243251567270617870410568821016663591236183169614602775102422513180501035104118081051383450673699260136842784020000000000000029000000063100000210480350394011387344143052735734221521010921318441498270332
SP134Bacteria;Firmicutes;Bacilli;Bacillales;Staphylococcaceae;Staphylococcus;capitis0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000050930000000000000000000000000
SP136Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Aggregatibacter;sp. HMT458034152023162855142823303114172713132024353027231877494133563893745042509191109981038815224426618888158171843111438141624702120811203995252318218012044346462330012392724121125001214132728271910130025123511253559132933422347232119251901115301616151624151529243409121918101727201023290153110418272217380160602423391078884200006000000000000000410007600000000391927364921272700000368000000140013600000000000000002322202614201412005000014008000011160000000415382601413152616044162218027000101422039251461532272161002264171980517351092643562816104300000130110000000000000000000056101421823929584210178580000000000000000000000000000000000000912000000000000000001000001091003312130001509000000000000000000000000000000000000000000334231000000000000000000000000000000000123513001400000000000000000000000000000000019000116122500000000000000000210014320500000000004100000000000000002805819302134000000000000000000000000150000100000201560000000000000000
SP137Bacteria;Actinobacteria;Actinomycetia;Propionibacteriales;Propionibacteriaceae;Cutibacterium;modestum0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000500000000000000000000000000000000000000007110000011000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000040000000000000000000000000000000000000000000000000000000000000000000000000000003000000000000000072910000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000200000000000000000000000000000
SP14Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Haemophilus;parainfluenzae257534603954180129212874519151803932474960584263253420812820266925852058460744544147507737834551525599687220706090047634654682276682767998561001410761947511825902611330102021033713734149131266777889247174582070716920145091230517758148061028515712186411514215561104511944912560121171111999062017625767279471758213345159151616813818107971121010642123981325681273789987556151091266299265663389547750885352767501695567906109710180979563108831091711924119991389414057982810080127741151013770119441440712025884493671056712239149651566315033133524420674540414693754154257962622972698485992311072106451069017126127883961400129424121433171045626584880031109882938360132481323792881199329477175523385432234375504258236045287241094160721008367861715243377550851071582115824564669621855722768335766127281082952331642511180099018492151168413322274931659983818848183902484722837204942982920562245611734403395552785781407120137841142674328011434206508148670583469939168666726681653824738641263136550672427054275788142291078716011140751312014094160631211712622166617356177861697590697793107446206126431175454048461108901132282311273310748127281249111886125651062211928137271318773561046410489138421027412475151491216599011749611124131371215395737883486628473921543132583904255214098111948958111771022712510131241130918653735245334364078273410882151768825836715213906813287105514811223887206583250531093240804038426708324843122614075322195779749959169764953141183477335131143731919839759225596601455322431833328930833043382183606134003367783418240407633386286193482134965370232836536848378803036034122348942939555574152423266513141609938695174510759372233413302749432464456016773424628326195361572388887615560705176422315043070285458115293067069819300000058060323750990444386297200923406367449175457848222363740111416239371759612610234595058711640333278425939064591000000201287013696686148661181170000101605454803371141361211013530701302755130216524131631356900000039272000000300495900000060412011360031200487677281755883209244115971019393460000402071000050892000001136050058520219508643686509364727675069452748600971803140296334316100441753081875719497023471155552922488334661552761397336215064041061377681699484199217216491021724252333914932365565725097693621664512134111481586920564150072264119863043187537968000010022102300040009551124212427018503960606392291470115708284971371632108193871350078712982932122513352
SP143Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;jejuni394676617306409401317258262255272340644543805685839696409478744515386455000000000000341815290231302301913012141005000000316162262322611611050000000300000000000000000000000000000000005130070000000000000000000040000000000000000000200000000000000000000000000000000000003020000000001600000000000000000000000400000000000000000000000000000000000000000000200000000000000000000000000000000700000000000000000000000000000000000000000000000000000000000000000000000000000000000100000000000000000000000000000000000070002140000000000000000000000000000000000000020000000000000000000000000000000000040000161000000000000000000000000000000000100070100000000000000000159004001400000000000000000000000000000140000010000000000000000000000002000000000000000000000000000
SP144Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;gordonii1851241928203231120231327142617241920281528244219441521522228427328302201377742505267690000005135294614487104781091430105811331006488790000004615881776610594385356505131294557072510001012799109088056649950549345665967460441268869067943155756020397108875003494802906747247145763577588415535549159997036451049125418201357413535555720942714571711668905101790315051976138510953924975765537194628225220126130000100700001270524815336441394102850529021522627276038002323009600060021010123144904270953395014088783001001348005640251244256324652544634595626700567798889158772015981185134415621194812979955125684811339931066643532112677963676417821463596512441146251060266457085492912528537761300887187725562432202615802893234926342779114212566135717861005136062119381807161317831812161566566656818257169521001251000000001200001000001203717212684220670002350016410000081200002528700177806267191301690369725010302570628704115948171814903040334695243727041016926008900032033417623200640013100010309910127721500000012671050958127911188317931601100001001919010001906618000029472971080076854825613195519253671039500000000000000000000000000000000396152184260341517921600000000000000000000000000000007121536507709729131000984122100000047031000064817087192364210469081000002741003559117411461203110000111500116190016726121612926198230450000000000000000000000046320000293500445624550000000000000000
SP145Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Neisseria;elongata70145113668482126164561031218945453028393272635552577147032857080050123576024181893767915820461513162413481650117333172703377142222004256481150166941322168148679252348381787106717701388792296628432320416418521385242931142472132169275348801511911781417984921638610270841331551832121672728310722093146114198125734312325572925613626121165459615015812012448125851022801071069510998133841052597182591219151335184621073229561549241736361520003300522613643326839854880005566991301700000384244444222342417090280426447510760526127012171350701161530812177199971335028313910187815056303540938503915291313971641119066581876185661221437510415810675751082255074218158775711311795966328310128093545272431091704391701841003501434309148228521581723681172101083672075912455539502931504700000900323280241600660070003001823122861596010392577131345000000070031700514003500000084000000044052000000007974013221851386527810015827944624578712062451161083005200700000000623800501434000000028840131370000000030000000000000000000000105000000000000300040000000000000000000000000000000012920634717335522000000000000004033546918412669225212205909517467125432382400001300000001020104113211135420601617000000000000000000000004462000000033726250000000000000000
SP148Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;infantis_clade_4312905073642632873013513042632603302294423024923814743243944383653763493244451405161510000004940193021400000009915288759314700010140872011241004855000001870565957475599122071352531801839625413565138702691519213454665758736241775627114124838892979159355853446054311482201371433752912522318161559026366539604158691718494104554366697372702801500000000000000018620844944713700000010900000231801600000000000000002855555001300000120007780230237223191011533651125510174447291110927450123123224130771561455712315114215036663212853804860841566517774155961341191424712515367127472313342572633132802782853387275524365194592392032402932181671942475568746710016200000000000000003140595295251979009000000001800000000006000000000046035001850000000049706000011000090000000000400000000000000000000000000000002300000005000000000000000000000009000000000000000000000000000000000000000000000000000000000000000000000000000000000027230431710700000000000000001500000900000000407012560000250000040080200000000000000000000000000000000000000000130000000000000000000
SP15Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Porphyromonadaceae;Porphyromonas;catoniae317287403726831396883697826133417181039455144465101020302020025020531292912001014372915232456467973532018936722025112314526119514517394831000010000000010000000000000300001000000100000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217161419031130000000057003500006579101424835151616193000000000000000000000000000000000201531192520215652200000000000000300000000001103040113827146110004700000000000000000000000000000000000000000000000000000000013000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316181120401000000000000000000000000000000300000110000000000000000000000000000000000000000000000000000
SP158Bacteria;Proteobacteria;Gammaproteobacteria;Enterobacterales;Enterobacteriaceae;Citrobacter;braakii000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001340000000000000000000000000000000000000000000000000000000000000000000000000000036290000000000000120000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000110000000000000000000000000000000000000000000000000000000002373255380000002247305340000000533300000000000000000000000000000000000000000020742187100000042892947900000000000000000000000000000000000000
SP163Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Haemophilus;haemolyticus5713110180585018127386121161777140625359541088683105831003672443322241051580014827519916322613753358064528535104124212737090966822261138123121311321321620171323282141387214272946274812411627212728362512174558715541755210385432677452511732366933406944203824314032486418241434212136233529023333248272741304861253342677161491714000000000300050030013600016400000090562921142581400000000800140000000000000013140121609805514019190220073001102212046622212171280012331919201351122231046790000000532000000007000030000090121064258511661200171100002104800600000000003230280383443111621101400000000004000000000000000000000000001280000000000000001000000081300000000112207702000000000000000000000000000000000000000000000000000000000000000000000000000100000000000000000000000000000000000000008211410000000000000000000600130000000000000000000000000000015000000000000000000000000000000000000000000000150000000000000000
SP165Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;shahii22737631019724223934534638627528018116011121915218130322023024922917820500000000000064664861903246485958733600000000000092414178117129209500000003000004040200000000200003000000030206000000303000000000003000000030000000000000000000000000000000000000000000000000430000000000000000000000000000000000000004000000000000000000000000000000000020000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000060000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000040150000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP169Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Haemophilus;pittmaniae0000013181800150110000013150190012036913715318724713332712310414317947258287181629485167100100454321476341150175059503227180741150500022160418265232689221776523782421832601442532355201502901397915523217623915920423821119918910135713972154577222161310538264153607411369175635151352157481911503062599821712912410326123414511625878171261841378416817717921332922417420514138969631666217424941490390954000021680009043130002990097002010000280291702836431446541367273885512000000001381303900000021210000065180000363161072465592179642510130471640400231333620205512826155118396842321113111111516541601249539563459152111191140191359520036412885361439772397110008087105022701961781390222531011019824519255100000165001400087172600000130002000014812923374118125961595213053625200000058000240004000000001400000796012000051351957300000000000000000000001100000000082257211202417265121166000000011000000000000000000000000370000764104210900000000000000000000000000000000020546754857692263835551500000001400000001100000000000000005512539525526751725172000000000000000000000000000000005375185208288451301050016350676940381253171328718541661630615000000000000000000000000158000000001195133614934010751190211250020018474981
SP17Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;australis4796677142935416053902313123634523663932804594233632691672621482562392121011501061401811050000002923535258400000002623082011731611630000005982423625120000001091031001621541219910448454378624257684546365202165179334291214227187273238292311348258463267772562242994143133873849215516718413420226719450344371749693881051263425724136130033741451240943639425723971720966350432027721024633137529129700000000000000000301616902812000003110013001400273200000000710001220150854068010016043000175000083711005017120313022121823930119132035618947549344044253518732426419936038236426826725021925830032424830928243827634340349359550435519215229025519713819492794967588565682759973348238332244530755059832754082641764242858253466425828246544044623600000000000050000904000120000000024002016000000000000000003000090026220000003539600009000000014618917800000001700003009252003370521349306120000011318319778143151116172344124000000000000080000000660046000000003000000000000000000000000000000000000000000000000000000000000000000000000024377991601671421972310900008000000070116927357168106047400000110266234199163270018334500501656021100000400000000000000000000000000460000000000000000000000000000
SP174Bacteria;Actinobacteria;Coriobacteriia;Coriobacteriales;Atopobiaceae;Lancefieldella;parvula11620618015118412484687366549618911919416319415410212815415612814536908000000035311024442323000071261201200000033825736282700000000300707622026025242101159131399112329222614403022821272422181878310880425212722242416311016141801420121510061302824101619151414815000000000000000005000000000000000000006000000000000400000004000000000000509000007108681167904546011812159890004469640016119101614823000830988851048000301078062005028504000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415100000000040470000202526113549127750249152052618232060152090000200070000000000000000600500000000000000000000000000000000102100000000002000000300000000000000000000000000000000471260512128433600000080000400001271356232756401650000004526281232000114000071220005008000000000000000000000000000005000000000000000000000000000
SP178Bacteria;Proteobacteria;Gammaproteobacteria;Enterobacterales;Enterobacteriaceae;Salmonella;enterica00000000000000000000000023214441800135119351417700094200000002538000000000000000000000000000024288888118001013947139312160143403251234604080036908439901602563901360085566218000040741382670275000181486029202814900140106844641820484043631198424464780001051526450630132007857121544280035796534442813801083873207038524305576010945281254197744400826710284290103302358363000001631057164110654000501404134833500128320031756026411396580665449116520774683467732594662700103286795711502478584500000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465130721851640156101781341151010445973991318212727179176361750678287737673244227496487658818461754661796162586674020371827663012400449330000512148112426421145132445447726646289687352212976447520710658738258268729618963898178546653133691776424878422371912853175917822272447382017043406183513894996103147828579104623288367777010212853888656248577836545242799046246961299956866613543197494493435151855958742301241414814202109229046135431020140638945112161699564462129832621500340175706964644775212616639887992911348940344376524377462273104849212765826257586809449821631917193371152523443328335160000000000000000000000000000000000000000000000000000000001400000000000000000000000000000000000000000000000000000000000000
SP179Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;sanguinis126249170145125126109144608410369179115176185152123138137931528511825636427524141535305600012710810584120950069004504554023565334881140960120273185131113104110000054363312035084923724274421067115590310328529069178251261986922777662684798785618418770716607370510440223261710334853903423454374295994653386046545054426076705204986378868578264054075145083954344033516036767625299411171922782275428604397326346322296065000095014166002202526035571153043520571021221917518220710120350150465000047014210110632197524580093344104823313110012155041834001097113256059933871355268859461264254360612541982850196113301134143410601200162516091386103912341219106277849210156875445451216989548645452113841451257058711209239527908451114833137016031130115110861591127416141551889820539491648123113149591531135914021235150312086688237251048108582814602586000000004730913007192195192012531202250011751825146800040011606017678011042671506321201011114361024711113034165180541433161136322836488883375633981536166914461924190001615890230072571131701149281291151321190000001466110511061584158512388082020900008225700002702340900023193041090044228214317621278724416017814100000006000000000434000000427000000041525433631410749173214000000000000000000000000000000002036323911171302162716581658161003019182986290722930177150172728614385878713798732212776065003402171809011254517581626158719252913901710687090681621155402482277233962341212700006015012400120154000000000035000081500387173642200000007200000000
SP181Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Alloprevotella;sp. HMT473438895547448420388408591288347453269176104172129142971991711481611371653884595111954948810974134752802272662522953013949652624329201341201712211315895148861408365153674615141818204721468038153837693911814652170101291394104681285214369244780172327483037175635302844585454529353369985389616147812903375183976263737800120985121528281912545000000000000900600000002164260000017004318453015622345000000000200000000000000000000004156120040200000000000000003033000004000300000000000000000000000000000000000000001250005400000000000000000000000000000000000000000000000000000000000000000000000000000010310000000000000000000031261838200000000705119619016000000000000000000000000000000000000012284000000000000000000000000000000000620445601119210000000000000000000000000000000000030045000000000000000011017036000000000000400000000000000000200500631500000000000000000000000015000000050000000000000000000
SP182Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;chosunense17733119219418517712615680831069813412116614512412514314610315214412000000000000037292227392700000025027000000000518252743746000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149000000000000000360000000000240000041000210000000000000000000000340005400000029002500000000000000000000000000000000000000000000000000000000000000087000000000000802100000033020000000570001443612000000000000001400000000000000000028000353003081000040091601781492000001241300001970290180320000000000000000000000000000000000000000000000000000000000013420000000000000000000000000450000000000000000140000015268000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP184Bacteria;Proteobacteria;Gammaproteobacteria;Enterobacterales;Enterobacteriaceae;Enterobacter;cancerogenus00000000000000000000000000000000000000000000000000001271005392000000000000000000000000000000000000000000000000011000000000000000000000000000000000000000000000000000000000000000000000000000000068200000000000000000000000000000000000000000000005410061008100065900000086500000000000000000137000023400000000002760021751011590281000047542077130626185603755716822122603939002951225538861627120019100000021001000001188000000000014900000007371023700560000000034002399101636328662162851442100002464727651111462778724000034072296642479334750230580023941285232354769000000000000000100000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458900000000000000000020000000000000000000002000000022970980089100229591360911328125402814330700036975191241997716361296824122005457226192505316999000030304761100003222610672200033555431101341423695129302351615013980111618121429591010651903063002979713228146801485328419506700317812191332338236122817547910017503399754199025911000012002202000001182888011121749334966456020955316841953030017897119952288935932450
SP185Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Leptotrichia;sp. HMT4176771085114656270591358877711666168211342596589784738921109468287913638296357600000000000006000000000000000000000000400000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP188Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Haemophilus;sp. HMT03658128754653401352638514015084102729697936719021116519617018556565883241307613103182774123101753361641656912715085158681712494401172102073261673039020417712170351564452002244161563545051215031122544244451636304549645554313582432326111415431412472618613554144018830593930315827192323214047363354284358477081305337109399828000000000000000314350000073000000001915236517589292200012037800510700000000000000000000351237803325142203400017089183511019915182732268213201260252221327112033353272322608015101400030807600300000612000110532841682515622762200030000050319307500000010000190280554553232232293300000000000000000000000000000080000001160000000001006050000000000160040000023021011000000000003000000000000000000000000000014100000000000000000000000000000000002301500900000000000000000000000000000000008102733040157000000000000000001400106000000000002017120000000000000030700901250000000000000000000000000000000000101450000000000000000
SP19Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Schaalia;odontolytica129721671955101914921347855100768577510197431126897128310701025831941117690012269501004961651089321917250040022821821025636417700000027040027525129334800008034950543525325418461165013387322422721319018414133599857412655989791110100828837620645029631431324119929942147733930047138930154256369243240939845517018025217212829925028469152851049568067280690132128835332729936143745050759652259364144293110232513192663553304292994166530800120003400170713861316241411617420800002790117008440001554111513000000149400110991111491102459392170568112120729098493331771420909162413322423532512712592738001010384101968581886073531157541231429043442031539036842155522833430239936859233558233045246258226528921830821231722126668810886101092620110689018954195813334691778305666525021130486813683123336685838444739162069810820128091091603005030505460781383735700000000007230081514091314055130011000162100121600885240000730005196125811310469438491109214417117305001530119121081271690050216421111022256373961210389127008123521821312115713323166209004001194307170120793600003047655215656382321217806000000000000000000000000000000002100262004630000000000000000000000000000000004093552803344043393863503864151321221711711687401310410079247385208141383280183280600322537223635953594211824481008311540111952111586517728968611201630182103700000000000703050000000740000033003406200000000000000080
SP199Bacteria;Proteobacteria;Gammaproteobacteria;Enterobacterales;Enterobacteriaceae;Enterobacter;asburiae00000000000000000000000000000000000000000000000000006260026060000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025500152000000327900000101900000000021900000008200001270000000000134701116518281143000024631070654082201998360811920019240015581249204401246004300000009369000001130000000000025330000000352700003640000000000105960718312268722063300000113151252954271318305100015546134291111614470105600010973128441075523000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000010280370048100998960494933553913085153100167128670868971141399019570024221040511847782300000016273060000000001031515951176705940111875750116129716260507755681285045500151700133485330583366861313723680014791948714563102771268723000076141682719208115560000000120510000012510092321435328860903013968915013603539480099414211014
SP2Bacteria;Firmicutes;Negativicutes;Veillonellales;Veillonellaceae;Veillonella;parvula158280195132186162428426175379354262331196292258307213500543398565438511639134584885215051258219124741911259327023041867690915703990760130311251244116289962917111750149110651345150724271943211026851992197376312189797076265582081189419121259903849193315851753160415211397185592554367167411007161581108812871005118876012419881028112810021353129217721746169114111837184713461396155520001438146314631331126213451537145717951998191116335533885184243405085105336317969989781442137116291368120286710666878671092991880693107310788881317142112671279116320741360149013281440172319440114613310213011157461846010313724681883127115305454013998829971653131213291523358317261875211659629721768162226841956137621651734143150178151643200614937683021927220492002200303186394555870075169530463240781914160816531503126816511730142719172250160022291969164219981944147019982107850128116231590135316401245171420031561149816611630148715581403157510861480161015131909165113091908144015111609157150552443558017661194115679218061612112212751831266818291655648924182214451535145814741721101911772387209020042725414823081472209521041822260019034941595387951337765393106581315081904107513551147102110871600373487014683632848253527131909166232761878185519061785177319631452171415431284066015206597116021431718238423101380385717637798800031060633760213774311841815802390193318310000002302492262291379944467134710456391716907112317351793149699529584001433120912701523131615801742123114500000000047140170200360030000006509748383230271345416466813293324251525620000000520000000001070000000072704000014011876293722582009273121751813000000000000000120000000000000250039052640184122142128215519722137089000001300905413501376201858265413191148191033000030203317254022761800235603138114159112014502341100234100413918539983928227743243898371628864186008000000000070000000003582553608601820819741911275040873784468503424700060000003617319
SP20Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Lachnoanaerobaculum;gingivalis2452472711342232217329911131161192151552522441831821554643729301520241430000000453540274528000000000000000000283526334426000000002134201702511020211825320110091102800092417821018019190251333274128331500292430241688000025291827192004322311641110292536281107000000000000000000000000000000000000000000000000000000000000000000000000000000000024001000001802900000000000000250001418000140000000005000007000000000000400003000800040000000000000000000000000000000000000000000000000000000000000000000000000000000000000402337180000000003020420200021144613812900000262102236342216720000000220000000000000000090000000000000000000000000000000000000000000000000000000000000000000000000000000000000842129826400462600000000000020202257331510360440000000020912018000010430202004408000000000000000000000000000000000000000000000000000000000000
SP200Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Neisseria;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
SP201Bacteria;Actinobacteria;Actinomycetia;Micrococcales;Micrococcaceae;Rothia;dentocariosa10720714910283100332926183924103851261031048859614571554589130115118163135801839419010814513217211897080014813910992151156104491004415412586914106050060404452443141191081662561228815715259613570391538472192347265221259324314189123171124424195296194193134151126413144213046352310482117861141011327517013919523615114315715814969179647014554741021608814216419811812641704000000000000994351114831687784254193000532830059127162101314656591611000000000070041000755913104403141166022016700412073621671023958596443546056561151228680931141511283637314243203523805085201841301451581211691571311441781571491281391391549310761906950846918319011719017618722419849941824124219042250342592144115861841203083942281623912555204840000000000000000201347011918716715417530000004528535540027310300000060191033592447826189380233427710520164220099715215170197243207543935989419374715000000213614817418049718312193519151501826772116086162951447711114614141228598411314272021121073000000552840193900000000013610111212120502903003000000000000460612000000000384016740136641615738452088405004096000000000000000000000000000000008631385460564445000291905393090270850975909433510793956764283378242033710272261912661542623535343944650423100014154803621136076508985127456800400700170330000016115503811603381786080050000001693416044617486632851909000000000000000088
SP203Bacteria;Proteobacteria;Betaproteobacteria;Burkholderiales;Comamonadaceae;Acidovorax;temperans000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000030000000000000000000179000000000400000000000060000302000000000000000000000000000000000000000000000000000000000000000000000000020000000000000000000004000000000000000000000007000000000000000000000000000000000000015400000000000000000000000003000000000000000000000000060700000007000000000500000000304000200110000003901000000000000000500000000012
SP204Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;vespertina315368272436365135364645268203270277300245311385323445296343000000000000000000000000000000000000904880160021000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000300000000000000000000000900000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP205Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;sp. HMT17535694433563227311934383228182734903819269003227372639310000003014172219190000001818901113000000142000910000000262040242419232027461179458981199936304452401735273523375033232544446033493342232730212922173133326129513650757472342840394244484444424120849371921750162734503322050000000000000000000120000000000000000000000000000000080016040000012060000006000002501316018013294918412733524819362919831022510016035132124916159182213161993017212005162154762465850353820031533250333144373329352611163531494100000000000000000000000000000000000000000000000000000000000000000000000000000000362590027546035000001550889015827072517090301155101178183108562933301448582431281901000003916000002219000000168331705700000000000000000000000000000000000000000000000140000000000000000000000000000000004956454254552934570000524266120111404832140282201510000021218362730130609151615622653243422600000000000000000000000000000000000000030200000000000000000
SP207Bacteria;Saccharibacteria_(TM7);Saccharibacteria_(TM7)_[C-1];Saccharibacteria_(TM7)_[O-1];Saccharibacteria_(TM7)_[F-1];Saccharibacteria_(TM7)_[G-6];bacterium HMT87096205114909876535135614534323215270190248243109141113127137109040200004200572009060400172411177126519509212513151497033003000235200000000000000400302002000065300044303000000000022840000300000030075000400000000000000000000000000000000000008000000000000000000011000000000000000050000025112011126168460154410555103139141095121719231512711861219182013147411101057147119781181366108884665480723518530200200000000000000001320200000000011000601105003530000000000001400037000000003032000000000000400000000000000000000001770000000000200300000000000000000000000000000000000000000300000000000000000000000000000000000000040000000000000000000000000000000024112440212110900000000000004000033000130000000019372310000000020000020005247159200000000000000000000000002000060005900000000000000000
SP222Bacteria;Actinobacteria;Actinomycetia;Propionibacteriales;Propionibacteriaceae;Cutibacterium;acnes000000000000000000020000000000000000000000000700000000000000030000120000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001304000000002550169000101100000000000000020000126530000181700000007952900000250000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401220150000033200405015270020000000000000394057036399970020024449035000003526015000000000000000000008400000020102014050000600000000000050000002460000000000003000000020000300000300150700404080210600592902550016011961090550018322700000000103203414025000000140000000000400700000000000200000000000308060050000000000000000000200007600000000000000000002048000004537005002900007760018002405000050030135030000000019
SP231Bacteria;Proteobacteria;Gammaproteobacteria;Enterobacterales;Enterobacteriaceae;Enterobacter;hormaechei0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923000403332000000120000037500000004000000000000000000000000000000000000000000000000008840000668046544000008101200000002082900008009000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002180000000000000000000000000000028420000009900066000004460301701466811140000000034600000000000000000000000000000156320000008901001190500048002003183880150
SP24Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;cristatus_clade_57818270121001890000471443374331132220814152819423649460000001271014000000002423602291862872740001360187448131824000000733115773907946831086267350986779239904242404710138454833114110121539753325838139134112100117137100179684484896810138127117115881731162991766249455343124891288421029490130516854138119462700000000000000000300000000000000000092000000000000000096500000000000000000000000000178136137115155196253246254383317443378215488252581251371121871141971652231023441592272193134412452742575242563302574171341012318813513912817821812391200447156549235177441469313173103611862835052955733277012816320125591284355000000000000001270000300000000000000000000000000000000000000150000020000000000000000000176386439000009000000000000000015600000000346367764243278600000000000500000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715574102618967630000000000000000320001400400001200011374606101410414150703314534229590300000000000000000000000000000000000000110000000000000000000
SP246Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;sp. HMT06624932641717329129714510011713420215028022832232728524512618714721317316442603747904900000027227152823000000167178111140114101000000411135655593000000075501291138710396831281841522111072151552061921648817922015217117918414220317321217223922712614423221417418523720489678798921241471242202181911742852202242381811991982102642603211881712511341572581702502101572741581931891882042680200000000000160000005220007720005081432970000440600000000040001150000140290001802200000000500005138138131173128187259134150132124190318246294288222266299103254336343230867182126189185165197155210173195211355275394174153157255155134141974534903424174543304214203551831702312233612932983154343482702433363503781681803182862902110000000000000000000060000000000230400400000000000000500000000340002500000000000000003000321041059100000509000004051300021505112695030000011410016010290847165014027000010900030000000000307300340000000000000000000000000000000000000000080830018000000000000000000000000000000000221631361281521551501430011500150401428395200507927857801040000404101832321432458634551407100042058818813000000500000000000000000000000000000000000000000000000000000
SP249Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;mitis9021697112196995288774985942454968146070252581066966951957260041860560253202920243531000000124106129126162115000000129174104898713100000021237721728516312100000021414940352631293399588562842181400180170000201900312827058523248503942362336223132372623176121896426180999517000190003930202730474924001500000000000000000000000000000000000139000640330000000000000000000580004600000000000000000001201581271701329224011610711083482781582562050320000250242714307911901356111576611931671151791152035716511646331745153635239239329330722300000000247240206255190139000000000000000000000000000000002600000000190001000000000005930000000000000000000000000000000000000000000000000660000000012000001091122105902864016910000000000000000000000000005700000000000000000000000000000000000000000000000003840000000000000000000000000000080000000000000000000000000000000000570231600162002003615439421720050401603432000000000000000000000000000000000000000000000000000000000000000000000000000
SP25Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;nanceiensis6171349100161268867815131843927142515491009104366798184697271116481752144716141508159903000007044097141866215583171293231304222201000008021340496155891038752260233298198698800000000000009030000030000000003020000000002000000300000000300000000400200000000000000000000000000000002000000000000000004000000000000000000000000000000000000003000000000000000000000200000000000000000000000000000000000000000000000000000004000020000000000000000000000000007000000000000000000000000000000000000000000000000000000000000000000000000007025250000000000000200000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000070000000000000000000000000000000000011331201990140000000000000000000000000000000040000000000000000000000000000000000000000000000000000000
SP250Bacteria;Proteobacteria;Betaproteobacteria;Burkholderiales;Comamonadaceae;Delftia;lacustris000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000030000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000090000000000001490000000000000000000000000000000000000000000000194000000000000000000000000000000393000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000050000000000000000000000003000000000000000000000000000000000000000000002700121332202003380002233000000000000000000000000000000000000000000000126003857469261813008432500615660
SP252Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Aggregatibacter;sp. HMT5130000002074181720121911014002524031200189276483922362178779016377123171152180139217185551171762171712501521151401159313713822519613893155156682720879317159103341467036101496410447123208012741141010714310116725310402104364171941214918716220461193453412132701293501481441824231106662234012801481501078518420454182156248218917671841301636513378967816317930711526861323301181329814825930246600010017070001070005800800413583720400013002501243123962856932220000224004250000000000800000800001020701791191711920871232437480055238104835553257354505387004940273767646751721061374270267557100128148430000202319216353443850168640310280003477557088306904232831934065890115710050031000006430000700000130080125106490160882871462414513818600000000000000424000000000000430900000059012000000000000000000070013000000000007177460019000000000000000000000000000000000000010816700000007000000000275000000000000000131761971451170130000000000000000000000000000000025534158142761222676000000000000000000014050800000009721973459000000000000010400384140297319218332732260000000000000000000000043195000000616149533115209100000000006023070
SP254Bacteria;Proteobacteria;Gammaproteobacteria;Enterobacterales;Enterobacteriaceae;Citrobacter;murliniae000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007000000000000000000000000000000000000000000000000000000000000000000000000000000210100000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331146860000001271162070000000332800000000000000000000000000000000000000000012081223800000024541605900000000000000000000000000000000000000
SP26Bacteria;Proteobacteria;Gammaproteobacteria;Enterobacterales;Enterobacteriaceae;Citrobacter;koseri0000000000000000000000001414832259000832698729311023814285554170024067027618867000000000000000000000000000161450795926880057720785737971140741601723106203702356002235365992190010301512221973500492134413020000306471978162401764000107227100184501890216009356245402372120802642545212966242346243842450055788938680339073500434740639122538002211501042383444993055430501703579927381029784449624862670710464176600400025026205883011803213752000013846384295277303566000276660213414324200660120017349320662350349131034547250363623142107436084026332055283890531703541837544013450306660000000000000000000000000000000000000000000000000000016180000018000000000000100000000000000000000000000000000000000000000000000000000003651000147310900000050000000736000000002897780512998103349327912008666396757597529554854243975385134115134946407124221641325374222421540832263093163443843382893232535177325173991340213811465816336227142732111228080286291969623712559788735254525068157433377336750291371635724999118609134611192854231538934109632055710346251311706134942382972612422561393501527210271103061346130872148596801878510140826127618546704206131272202781172142584420635375743993481943155730387191702762241784256673711116873293683427227831282551924736441259403032028975513416051641525477569884556916578675800765422942732674695433147254469661780579521844741946367893510642157143013853808524525839250475248583431021768331001733044966683054495531341368352607011645108549442069829666193881844219585000000012700000000000000000000000000000159400000090006500019190003010000000000179000000000000000000000000000007947000000120002360001864000417000
SP265Bacteria;Proteobacteria;Epsilonproteobacteria;Campylobacterales;Campylobacteraceae;Campylobacter;showae1221281504512014214410232712718326621036860183637652532243945756519389111691553442732072152562382362893413261902220261920182400204096111718380602051602162206710150633319141122145121184862815515321290000170120260155552393938543081321050441161831161166484197771115325749242023233203276012991213514945314540020443504902019368575923380000000000000070000000000003128002145271292210030110000000000030000080000000000000024140347725301419820623294088014044721393164714161424491659713181933181991983305040210190000000048372250002005334461101569000040000040160000021900000608798122120757010000001100000000000000000000000000400093781151220000000007000002170616424215860215524237800503691451832943262564280000005400000001000000402000098000000373629390000000000000000000364000000000000231525213713518821841700000001400000000000000000000205079383371175956635723422200000000000900001634663324026220403204134211911923772209070702093102001572942593443952231181160000000000080000000000002920000110573110234171124000000000410008240
SP266Bacteria;Proteobacteria;Gammaproteobacteria;Pseudomonadales;Pseudomonadaceae;Pseudomonas;aeruginosa0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005530000000000000000000000000000000000000000000000000000000000004020000000000000000001912300000000000000000000000000000000000000000000000000000000000000000000000000546000000000000000000000000000000000000000000000000000000000000000000000000000001278000000000000000000000000000000000000000000000000000400000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004000000073850130000002795000000000000000000000000000000000000000000016000000088347000000071059000000000000000000000
SP269Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;oralis_subsp._dentisani_clade_058641075863577854973971845412384645193736241632364624171519233640000664044393619000000457448248066070000651267113270608030227434141773316323211111114711576751262236026343311396229562361298632457799369551222828702771473027332519814173608214093134914152932243065341654101002002130111632221392312010000000000000000600000000000001470097002100909000000140000007005029029040000002403190008597943885390998270112481377863106111299070731138389396474691005659110172708447132686867781169310011716611811015219514811811923923036121125565221981657511713213417021111649532472833914132500000000000000800071000300000000340601100000000005300000900000000000000000000000000002303067060000911620167000000031000009142530000141025519089900603202600007040001250080090460025000000500000000000000000000000000000000000000000000000000000000000000000000000000000018522252398157501021557902811140027520228204550006007102716613816014035719426428191604101814025350480793611717000000000030000000000000000000000000070000000000000000000000
SP27Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Lachnospiraceae_[G-2];bacterium HMT096245361628186277383170101979168352646449553677583125317052576889554402904920000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP284Bacteria;Proteobacteria;Gammaproteobacteria;Enterobacterales;Yersiniaceae;Serratia;liquefaciens0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000900000000000000000000000000000000000000000000004000000000000000000000000000000000000000000000000000000000005130000000004492120000000000000000000016000
SP285Bacteria;Firmicutes;Bacilli;Bacillales;Gemellaceae;Gemella;sanguinis19232630914927422842144052614223519023619420016949825791806234661641446670544016292772587206136825886345001712131558423723620615126330814361490450594340375371316014097228295166103140981246545581660345644148762042029933630536627125128820730821825525230616021115332543247035440230130329717519015111410621017614362365144142747157456840136339230353235639733033044152846553067269150642937931250436632740833553400000000000006000301539010099814300674023016807401207100000000400100405740054747200025041047000062914001219361761069933124655011716913815496187228161156271275245134152196169140691931341011051037916115314215211013017012777555068525810974206214130220189184200192169270103161119198323191295239131260250231230378220158160151248477000220000000003000084002200000020400000040000000039400000000001900024000000006016000001100020268439021407034272253591853279435367602448232877207131611614389851105310215693515194147322705782276717585092043882158529595135901990141726322732231067063104250000000000000000000000000000000000000140000000090000000000000000000000000000000003021052792701171081421531829816152310981132028872113513658815940531364608313281207529102442421181363092610686387315357188737319614613617000630000000000000000013000000000210000000000000000000000000000
SP287Bacteria;Proteobacteria;Alphaproteobacteria;Sphingomonadales;Sphingomonadaceae;Novosphingobium;clariflavum000000000000000000000000000000000000000000200026000000000000002000763003000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000030050000000048053800154221638555466600000000080002038830181440003603300000044201218001029200309110000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP288Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;aurantiaca1122421449410490156185741331527225813724419922816721925223024923723200000000000015181121301251110673000000000000102819151630403000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000080000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP289Bacteria;Actinobacteria;Actinomycetia;Micrococcales;Microbacteriaceae;Leifsonia;aquatica00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001500000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047590000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP29Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;oralis_subsp._tigurinus_clade_07110851211170123013071219017110000130090014000000093698964338080080053685045796212081714024449625529220717192230261725900187000040182314212729001201000000201022102081011130102510805001400121021142418245101361131090018148751720700009110000000000000000000000000000000000000000000000000000000000000000000000000000000000552328463787445544522455242687422477227192034233241340375248125343743272263318414828311097832567143374785372661391192660012140481675676135104501515182528184668000000000000000004000081400000000000608001600220090000000000008000000000000000000000012000000651500000011001400110000002404600009642732500000000010130000100019011608320801148031130000001018000000000000000000000000000000000000000081200000000000000000000000000000000000000000320001150311109420001210041022013122016230021120231082423673589934017840412025003600000257236295721340143070000000000000000000000000000000175306520360000000000000000000000
SP3Bacteria;Firmicutes;Negativicutes;Veillonellales;Veillonellaceae;Veillonella;dispar21632338718621325844550033047251542452440253547752945487490388290169891267161113154215104324365302500423389282204289264375247442504592388440185241333218218176253531432574698561435544862600608456344160614221126101975457418114913111616111313110223115515822829330728716117113210519717320024417016417920324124720527524010113513816721117516112613915115817722521820418320112963961731671321731371271091593052112291812311561551462252222492561611431771462042341482191631782131312099717223322039230006114002501547025814563626102748001147311216312627795152744916212106592132433282252393382292250000560014371966000004423531950489335737000000034311824327120417222221435819525765625041755528357239022330548816476638957854322922425137637519129221416918519414423030026316231222019620224421222329234818125423157341111914534736226126811332827524219826436516331615317733796201380223139447579384240403411328712366136165980106218196427401113441296303608945520001871410742157395826587804626255205224522233412913967254555230304003600000161245001461741600147138036825019000111000319560041129117700000000069209216401671810018312112429927156752357661431681330000043147725647559200000000304300110190000000000001601215056222000279251149000000000000000000000000000000007915224715416919515610900000000000000000000000000000000129185148781311681331130000000012000310004951086303342886523226900000009023516713861000050570350000171142212014020719726838942539536400000000000000000000000113231000065003503984882660000000000000000
SP315Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Alloprevotella;tannerae34749344626824324138043539731241730521311715818915711919420517523516820200000000000017242326191410411644000000000000182918161593714994000000000000000000000000000002000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000220200000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP327Bacteria;Proteobacteria;Gammaproteobacteria;Enterobacterales;Enterobacteriaceae;Klebsiella;aerogenes00000000000000000000000000000000000000000000000000003200012670000000050000000000000000000000000000000000000000000000000000000001822000000000000000000000000000000000000000000000000000000000000000000000000000000277560000000000000000000000000000000000000207028430156700000002250000009300037931800038200000049700352045400000000013860000037589800007100031590004298000000058201065005946131094000001423700000025400005726000224010000008500078101357000000213142033012000057656120287035095000436122000279850002792900000000000000000000000000000000000000000001610015374000017426865324494240000690621231021345800001350641714747114000042031124651412406000000000000000000000000000000000000000000020000063900001780936559828963000060310033550711994000016026819123910157000040261898936715939015540000006633880000000192142980000015217101794888000005508000024533030012830005594576061061650001530000147006936360000045470580800000020464485000002965300000000000041368864002260000513598902705092000135800016400
SP330Bacteria;Proteobacteria;Gammaproteobacteria;Enterobacterales;Enterobacteriaceae;Enterobacter;mori00000000000000000000000000000000000000000000000000002610011670000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000010541001900000013480000017200000000000000000270000580000001290005780412175112450000928340228830507851479415130766005284977903464808040000000469300000233200000000000000000150500001300000002668013589803364612431612802000058116399239753112520007977725356356970503500547071115473250000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109500000000000000000000000000000000000000000000000508025001810045822603215925226087550008166383941253169633072900937464359883560000000678122000013071217020047907460708392500544717813420984215520532327511501766062600627223472608287260769350067084286694643445957881002932838196535154000080059230000221315340420402667129181094257684238714425137913124435507499
SP34Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Porphyromonadaceae;Porphyromonas;pasteri36755163523125583786361169467758574465527111609328602163315429652847229045864569413149143979473026751831726159636866282960010529577753586367535903465503333601406148120991677169714624127724645402935008045321060101490941145146972428441143371307122981786186616928721314891222293723244413785271644341845883189336277402542581382941703172633605106826826207957117257097507779421122648836855710315435473453251288507443265301248232176225306294170204241268165166170196241310155407341381383424153284348281138181238264111252145209322277431569000000000102883718833234012640136014303517966077402309506525758091341822351521593821852140140001370000614300005051407140000957505750362442783332632971443461681635193519322319951851489112486187102123821741191379910580369392276409343386396339779457774764692902832371427109462922514647683214657015384455916158646449224519630716211449218800001936804016141173846000015003039029822032131114237430590989510010794101520000000000415000000000000000000000005192442052110000000002000020500032652100745310918160000270258292104343091397200000000000000000000000000000000000023721278300000000000000000000000002250000001971251581208714510733000000000000000300000000000000001218682551109889820000000000000050300406179861921523200000000002012047230100000000905025222929234175986613000000000000000000000000197551400004001643363800000000000009640
SP343Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Fusobacteriaceae;Fusobacterium;sp. HMT2043236191821173334283126432382340121513701789283338232756020000141971015900060031733655723700412301223211410200001101701201942504000429648351411100217231115816534726415851111719652376424669124140129646671232662351141401221316543570120973109419913971861741701020617400004401621000000000000000000000000000000301726503001514270000000000000000000000000090000314252166991606000500000396000005291000300002100000719001122530000000000000000000050000000127600000000000000000000000000000000000089006000070000000000000000000000000000000000002584637800000000000000000000001000000000014912010527211314225440000000017000030027000020080000013050000024515100000000000000000000000000000000846896551681862214260000000000000000000000000000141400351337831548013523450000000000000000050000000000000006398632332500000000600001552120143105149461541365200000000000000000000000059000000035674255919000000000000000
SP346Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Neisseria;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
SP35Bacteria;Firmicutes;Negativicutes;Veillonellales;Veillonellaceae;Veillonella;atypica48873370843744450441751833745950435710698071162889102686010341140117012199661076792163085799615811324726948105292759856495075191383911147179211010310556384409576946813893386544462636305925193264231422102959426630952634228119713963453612722613121040120616762076181523461957196241810816201776868230910971562107695452611729231490110814041015147515591745182422792458250283513241540176218082127197619152019228630313018128823503173275612081136137610107531116114810601699145725271851167817432945179214901612154815168721386115912961750208122251812228221661898194554105583132137551772810161452011479018310254906811558787077331018079523152634143526235094959812237823571228296473466395103265175195533201014847101054531553152618485101331501584138129046905116530511661165064331032733563380238813241475437161954202717862942267024592973433817001992348013022705246234973061322820603016327435313215333838872543255718062937276636103239336536922569334539863190310631452337133110781401156520731782233824763741268528502699331234652790249411311582214922211211148731454183239122703855303238462515116777849277738330866374219616835113324113461179105105353343347268093422227210270211607701524138713521469354943344142624824845230663035042731400481170362362006718120311526260001753014116800551061469441319462000033025151824188500000060297213167154155429264240476423246410748103612531293128338386378026211812811532197910768061367120390240000001423919825741086616349000030002115719910514712889412500004682712832230000000000000000022600000003630001540034329252442914117536228500000000000000000000000000000110746552832423343365695532059825201001100000543647937358164107190230261183123121731677522038143518138088120894506512743164761146379238427567148516022898329441509432397115368914201526181812731241172500000000000000000007000459117700003450217239358898945900038000000120035440
SP36Bacteria;Proteobacteria;Gammaproteobacteria;Enterobacterales;Yersiniaceae;Serratia;surfactantfaciens00000000000000000000000000000000000000000000000000000000000000000000000049200000000000000000000000001380000000000000000000000000000000000000000000000000000092600000000000000000000000001603000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP366Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;sp. HMT06160111106505072104102618584727670929592877992671178280501010500000401511141721100000001118151009000000447532583813560600205151171380512201708025315028624120342315222212220352002911262734211900080131311411620154145185119242130911214200013001812162201317009070000000000000049203385604973000000000000016080000000000000000648222201504200002200001706609001151816183710161895000710181538924635444876710108261620126544822321446544720168241925121021482520182432330202714312924221590070124724930373817000000000000000006530212204370000000000000400000000000000000240040002000000000000041304000000080000000000000000000000000000070000550000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006160101416000000000000000000000000000000000121691500000000000001700000000000000000000000000000000000000000000000000000000000000
SP369Bacteria;Proteobacteria;Alphaproteobacteria;Hyphomicrobiales;Rhizobiaceae;Agrobacterium;tumefaciens000000000000000000000000000000000000000000000004000000000000000000000040000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007005319000060160100005558101183001136024039019000000009000640006619000033030000000003070160504000000000000020000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008000031000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001800000000000040000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP37Bacteria;Proteobacteria;Gammaproteobacteria;Enterobacterales;Yersiniaceae;Serratia;nematodiphila0000000000000000000000000000000000000000000000000000000000000000000000002040000000000000000000000000880000000000000000000000000000000000000000000000000000048800000000000000000000000007981000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000080000000000000000000000000000050000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002840045100000000600000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP371Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Haemophilus;sputorum132207219941672083102861542794751811231211841151151772362432002241612591311122182896249231117141110131011731716114614241486216300302178113150731034870971140000055511066636708702585359338389153345230437830911962169512193846124314142572839634840141147959443838572622836836995166405051181278131293753882549221551421004840273510380456075441963391307820461712790863322741196211145425150000000000000400242000035415881880038000001543852511302000000000300000000000000031000003444713121314152012660310312144220179541534227211020155353443659131201315106165211481490457135151201015361000000814214011652155152716535600000490000007000004000030000103040260033110000000000000000000000000000003600000010517000000000700800092501111378856318217252805931744201028213400000000090033020000000050000000000004182000000000000000000000000000000000142817415232600000000000000000000000000000000174112402212130000000010000200218653535333963941111105017793780000000000000120310000000790000000000000000000000000000010035390000000000000000
SP391Bacteria;Actinobacteria;Actinomycetia;Micrococcales;Micrococcaceae;Rothia;mucilaginosa140018382251929180518452831673562694353871083926119313991121900294536396428350386240293296454178296201817009830640640740534577609040702595474341282619268215436811111919539533118596031705910122473233133161051622412279351961133001641331471541691292801903031547110110120883273141185147127831541351409414530106233226134010252432975524713253240438204208399231453238188226146339477178811401431722859476251372930650210053881691061500111264803170023146292035124118721416309396000000108067275223812816245156153114089301144195560108747616111111621613653610364053702306116081417580785332743314163571667110022131712831103354242914032091455922742221663762011021731852471011801721583112991301759024381120517019567139211867319182739703051033273606213153704631861272695222244183214222096139244026723921524220813039662508810150050482237603017612512014213924700001901423175217521316000123571811517111321332085009414961962501370183219113102270272310450121101077382142183800000010400000023111662106424556487692030409213597363756496642000014732571436232222290111220121310463427631022969232219024204338105017941437110000000000000000000000000000000000000000130460500000000000000000000000000000000001440914216126352306300771252210172831384492132294564427620788929813177331185080604049155400930158140332459020115469910720900003150130000002500000000480000000090000590000000000000000000000
SP4Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;sp. HMT423201423260243253218301456143225296188311260354418315244310302160283255273269044002933296333183460189176173476460564518636620654446000000164819021336120619731739872507710699625921073700706466442121308006062638015961812165544732525055735928692632265194558053864959836916425171021457917116141412052417583213562853309939144341366835553467372874295813677463235220555146727262500761986299528664086346642053144255526431524190447464458189552950777242958381553675385736422709249130224175391541758721473341255898711597475037403526573805350527827795545171806133255403200120511520594221029000124861430815647199501592622291603902869249531556616594714378184318184027931599631487939049182174340954028433557262950146920023703469422854186573523978832683099452360835416923348820459024531574835462252857829129661688518851872196213971831156919331360260711982540801186013911336150710852651703243155200349845454619469492984615141382808103919732525157017851472449014251864179618512612225228192090193129281807290426952553261221172377205421762625136615571515107714903203316733622685196011021371147113891479150212252511205624622572750331341801836491240000421000110027031668733119134951273318334354314320005381712772115314159571004690110752982271126250010800482553537112624514366712551373617503326000036955316633466234315523628901143061453737636113674002616250651478254828363089133323054475818612152949413445106806239134031303015887276516220414114892492113398212698130756817569174600877353978344613489068467021471738109725924331101536422115131331157413269877137891148328851592636373811895414307711359091536207414601008600937266279453793015703334440079581075213369744534976185420000000623718515026154576820500000040807575553243288824097077462225216155877268027594519091153160010754483756133220572624300010038167290734434951702440010331594137716391622137959073187363143017231139602124253613494525025895343010859166308222685631664038025647108773054337520226241544154829037986444091832191513051426157636838607592711528244114320660323391117375353933312633134071613317110034745113153426170000003735487110855661400217000008325812297669102235137633227713079360556581316000250011600107005945
SP40Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Leptotrichia;sp. HMT2155295987083685596444461756044014604824404016797035453991942433562762152259620212714614614300000021018116115424019500000029849127740543337800003026842125731222720000000078111921121591312192483413711629712440728232812915292146139187171180159181225296273395353432135177257291205321307324158297326328129176170177292489229394155165175210189319216361176171831443164623584422211832242502803453103111121601361540400000000023000005000000000000230000001080140000003000000000170902608400003264060000012000002463183083221261231249899122122316265152378617385166439010550102175257311727722416917743326462863158255158761329320362202373343261909227843418919341219072243027441511521108141774113992510700000000000000000005000000026000560006000070000000300000000000000000000300100040000000002072162855470000000002500450047430578430598162521376706237472322611369393347103400000001170000009000000000002040000000000000000000000000000000000000000003540200573310000000000000000000000000000000098170710579867506859237550000000000400870117834931139950630422116231865178268064162039104018850270419324735813100000005000000000000000000000001144000024007011600000000000007100
SP41Bacteria;Firmicutes;Bacilli;Bacillales;Gemellaceae;Gemella;haemolysans96255172125149110343120363120104659210810167295021424128951361341101919930300025529736123734028201100001461119343107126000800379100447346152126600000016153101319210065385431375903234356130221631364252424916394471701086354434741203328162735004756335450374638305537774837243763582961576259552965433427475864000000000000000000000000038000048003000000000000000400000006010000005000000000000002838313923332212373327452630481565961005846515664113754964483738339981567244397230321921302314311639283630453141346933605548295941411223726345111149896438429069000000000000000000000000000000062800000000000300000000000000000600005000000550003000000131000000400000013140000240032510215260004090090301400100000711920100005000000026000110050000000000000000000000000000000000000000000000000000000000000000000000000000000042263027233523330000000000020685392934820137934018141390281046112420132100024281308308005882213000000000000000000000002000000000000033053640020000000000000000
SP42Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;graevenitzii93186150739614430224126323425617324126724220110811880141118920000800000008079080000001937181941240000002938522510210000000000004000004000000001000000000708070040001261005005130901080001095000878150860801060000000000000000000000030000000000000000000000000000000000000000000000000000005009001823141511062010196347149120109194011001318129879812102171512160100108901300011087001100070066075007077381700000000000000000050000000000000000000013000000000000000000000000000000000000000000000000000000000000000000000411000000000000500570000000000000000000000000000000000000000000000000000000000000000000000000000500000000000000000000000000000000000622182111312935000000030000000033135153880360000000014141570000000000002000000203000000000000000000000000000000000000000000000000000000
SP44Bacteria;Proteobacteria;Alphaproteobacteria;Hyphomicrobiales;Phyllobacteriaceae;Phyllobacterium;myrsinacearum000000000000000000000000000000000000000000009343000000000000305000003000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325016110304001900116300453876000071950033024000000000408637689152069953040650335040507660004154301339100000000000000022000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000700000000000000000000000000017000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000500000000000000332100099000000000000020000000000000000000006000500000000000000000000000000000500000000000000000000006000000000300000000000000003800000000000000000000000422000000000000000000000
SP443Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;sp. HMT0645077711744536558524060484357759060324443374703300000000000041331913424100000011510395697711700000071135705346153007080000000002516330041551142826256282000000001700000000400000038222320422232310140370001400282102502360026150030000000000000000000060160000000000000000000000000000000000000410000000000000027000047489752916966751109912375107150901871591484102532351542692894291039711412672117891481321539916314318412818488768697175105114663422703762254872403363552922001363631776663884841362121601762201892401921042403443402073500000000000000000034252646004800000002200290000000000000000000000480560005814500008000400210000002043868000000000004227000000374200000029110023004801680000000021600004531120002033413300000911024012070700283000000000000000000000000000000000000000000000000000000000000000000000000000006795553558917997281750000193027635822301127379109326636336190002100034266886344443023792163474203178175967610002400440521700000547400000000000000000401739000868101000000006411447725520717363887300000000000000000000
SP45Bacteria;Proteobacteria;Epsilonproteobacteria;Campylobacterales;Campylobacteraceae;Campylobacter;concisus5478078774036175238308926927068846736235407916707707278569448899017558603706573885645854732452402322202451482917271430642701343124242754314736452909234724791833832782921274042511152421662579929963715240324411998149043093446354533881737165614616724932429562155249162154167470184489423420982607222713324520013526171453284148373787210014966741913245361318628837375564390726248415375543290440309415191196195395196236135266397459118241290127420172433694311631821723583590752031042531612181691725545920000073780300026249570655331391870240789252009588702687197198876543112845514809222414820102908045500020033000001300700009640840133386094255482642981731575084671525711525591132962871105994914839141736070695122849933367946873780192357279571683823490217291686964405017106141371119023061502410691061225513171230965564530732618625346123711252000025121006911321640290174100671743308573178765925218513545982718430161181690000040128000000200600009000300750020003022414580000003081600618201418132814110683129259117355142200037171233733703692552000000002631880000123400006111800040333102020001512143140000000000000000000000885300000000040148184108213339382261000000000000000400000000000000001568420115413781142794782609542260000503322000033525023683389177835800401706050379847432616321296131306418350135515513413749228182818413110717181660911106291600200000000000000000000214109600000095833592474578659222524500254604998923052510727
SP46Bacteria;Firmicutes;Bacilli;Lactobacillales;Carnobacteriaceae;Granulicatella;adiacens640980987474735828602444458548640591494357609456436359358418346443356376462783605785832620123111133716113133107118119125119000000887100374170679289074359212362471432421371201059923112212121954968711327377676488585791355324617953317173227762872244914681844141021211653149220571367162619631717207817901450221916621943206819972083206420901919164660467068362359588575468823022719242016913249341338163397100411729791501170416581412163116291784112916222469135030692521110511466201089173013431085173747405543621171019100172149815131281932651265144132871675737904283985193852220386814613532473901927463923862103645816254724411762650012159656946830880511267166742518516201312261675627914317768161258281114281789277294672583973662819752188132025421927223829332109106921171579130610951699159813871438117014041945160616161934221618462093146426301655254123062046111610181075120383011029591095429645323511397432533362335454741408159610171012791179818641305257031191729270317572813115818291146116512221362156724603855327783560580040311365219561719411870227517645385004040050010038146701064718012114416112640725716501512100254051010511243261645734809452100907059161063830526522148344678154565678857230705337147251021122481815449148767018424722353448493103273106130100749664570696805594558964435513771146106748105647693424102091242166687722648395772116007810816515000000000000000000000000000000000242142146184111105164365000030030000000000000000000000801252146066499878096691181813391910411168565933193422123623932311195076112552106714331149718757111291729137582451120391393728394996222108124164104329128419061045177197135280191211228165461980000000000000000000000046306690002643049062245326520000004000000000
SP47Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;salivae2484344202152782572993181902573812283882743633434182884394823674943424192000000000004243304037602644304718220000000000004372494429265936474912120000000000000000000000000030000000000000000600000000000000030000000000000000000000000000000000000000000000000000000000000001000000000000007000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000200000000000000000000000000000000000000000000000000000000020000000000000000000000000000006000000000000000000000000000000000000000000000000000000000000000000000000000000038000000000000000000000000000000000000040000000000000000001113246780500000000000000000000000000000000014000000000000000000000000000000000000040000000000000000
SP49Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Schaalia;lingnae1012181821131501359784771161068515112317412814712012513411813011198000034130000003637213050210300008112194857510300400045975840552400004001115201211000313611734785977153212172208252740404728365321044618962467347704626202029444539623530165888362533251115472140443745711311691432220280363259000000000000000002500122414800000000000000000000005040000000034476750130000017000090770090035503924233729253174439560597048243638191423151956493513241582929721126113168859510019202630500532174887412011291901542334353148424155821125811275146565427454150213100000000000000000531826482414500000003500000000000000000000000000000005000000000000000000000594620000005000000090500013201756510000000040306400363926500000000000000000000000000000000000090000000000000000000000000000000000000000800000000000000000000000000000000053295930353641540000000900080000369226215638059000008004576328700000000044002914360009000130000000000000000000000009000000005000000000000000000
SP5Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Stomatobaculum;sp. HMT09717920020716016821934134642315817117425125621730935546979395205110451900000008710573811366700000008626218000000651577211995720000000003406112169300792614102900009614230000291228286810330240330301441231373970040124192159601271214037130134831899753331541478841847010029681061691280267360000000000000000000000400000008100000000000300000000000000001800025000000000020000000184100400006160000009000002002000000000000003000000000000000000000000000000000020000000000000000000000000000000000000000000000000000000000000000000000000000000000000058290000000003204430006000340951714040630000692961717090000000260000000117000000000490000000000000000000000000000000000000000000000000000000000000000000000000000000000003501004925700000022025050139660446126373306130000530000000018000127283080590100000000000000000000000000000000520000000000000000000000000000
SP502Bacteria;Proteobacteria;Alphaproteobacteria;Sphingomonadales;Sphingomonadaceae;Sphingobium;yanoikuyae00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001200737100000000000000000000070000
SP51Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Weeksellaceae;Riemerella;sp. HMT3221572702529616320325724718720930416816389139115151106168153164151132143000000000000058000508000000000000000375000543120000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000050000100000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP52Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Alloprevotella;sp. HMT30869012711030625746702541424376507467396121685711889801133870498683573760542604045806400000694875497350000718088774120000007313473757147612000600020005000430000000000050600050000005000000000057070053000000000000090000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022000200000000000000000000000000300000000000000000000000000000000000000000000000000000000003000000000000000000000000000000000000000000000000000000000000000000000000000000000000020002403334000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000020000000000000000000001626651524050000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP53Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Neisseria;flava79170151811068626138312518121815013378105961059536336528935529434517952973155418092733204072408846483512724881710030420930853862437144092645172541533025085228571034613413424043073380221433504316902267715947777862387299162144314192157933762573123071798319951102509430929345050051225362331226617479514296866158309605355154446475957356525683486108741382945868990102681867715401804120192198212646968524016208043913715472233967701186938111678761374873179098088816247825005461029101252711188585331039510282506109579881561110886626418707051534714312210821089784015128291025409565734540292867144821320615122227038892466393786033410526093301569012611001509202190469950510111034178533017917033575020333257353289411833932511664339721380180001441167322220414262207116940281647121319111178186514218001275270111531318732116011406415881783329725691322151119421567154316751145178316111379163712391303292028901877228314822403185518961832152770711511587102112231124118314389321324574761588868442239482200250313662222209121592194178337436775752333744995301940151623133434584605575229783099322373133131176336656181259021816333235462786252872398499758181796076785038181360244363409391123745127286832284120348803706509534442945215856563011395534520063830621249114718076151440275281320336536781912296262208151614960953517725229633405129962230791346820852813056120107107109000020585581219652134444854535910244033985681048102014381735248841065522233634783152511941131721503211081181329400000114540720349654237387433000723002865342316951584449640221052052002742480000000000000020000294001204002200000036218848535612354362582520000230093000011001480000382109000041670332803939223222441209771995901028120320530217523341249641372571293621795414187138562169523291471254284495962408417138131321662657154208712874925971210671120397172204826832610246750207246691656192521406856183368228725332408130045000502604800041549170850007300160950610000143913239732282615110220884010278177014734174029390162312190406235
SP542Bacteria;Proteobacteria;Gammaproteobacteria;Pseudomonadales;Moraxellaceae;Acinetobacter;guillouiae0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059700000000000000000000000000
SP553Bacteria;Absconditabacteria_(SR1);Absconditabacteria_(SR1)_[C-1];Absconditabacteria_(SR1)_[O-1];Absconditabacteria_(SR1)_[F-1];Absconditabacteria_(SR1)_[G-1];bacterium HMT87533165052732637227344450626036143129113590168110137114139131106138105107000000000000766331485941011719120000002000000286647222717210131513000000000000000030000000032000000003000000000000006000443000200000000000000030000000000000000000000000000000000000008000000200000000000000000000000000000000000000000000000000000000000000000002000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000500021000015242503473003000000000000000094000000000000000040000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141930120000000000000000000020000000000000000000000000000000000000000000000000000000000000000000000
SP56Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Fusobacteriaceae;Fusobacterium;nucleatum12719312575172162109150204115186157907113515910190114118881137699101183180234118263613036008054612599192011201323760028440553036318363741111195789761066352310192303376911718516293136330243121156372705444437853285935212078119125130467892873855989715291395196483166185475674791556170262327536310390170463316331171673151725894717024202708593535169648252204322366396551992686883236165790292179000000000000000004944346101280629569000100061421022137218921146115770000020300017047000003901696440004000000154352125324808710892018097016001547628302014945993801403632291591198724222288421257012338598221221816336400800000000122205612900080005647751613003511000000000000000000008140001100714512640602145137273447031000000000000000000000000000000000000972366111469100000001000000000120000014000000000806131587010782490168114505186000000085000000013400000201400003112061700002022537966260000000200000000000000000000000003869518381365220189713465179000000025000000000000030800002100017217650145023789978701037115900000000000000003215700200180000000225591331285104895947920201121548026621189329802782334743191725112583037274811990000000000000000000000006640000002178176910615031235861004000000016501339626
SP57Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Schaalia;sp. HMT17286243165871911651021361441019284199127207157135137114172110173141163152001919140050001623172425500000040453234434500000019604353719000000191641402616212668917515186808310541252439192034173335686140265649396088925152474211151725123740368344626875721361173128384025572349517964529367679116252420444620410000000000000026070000013800000000000001400000150000000002874000000000000000000000000017334256584036293513411361121123811339027765920334368327051478442533337466345354963356244682643106715281191305511911017810923498865274231127888649989957317349784364736710115400000000000000000302252114014000000000002300000000000000000000000000000220000010000000001700003437240000000150000000011002016186323000900001219303214415280000000021000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088556262103735373000060715000080120222618173729083000000005778688900050270270322902438014500000300000000000000000000000000000000000000000000000000000
SP58Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Catonella;morbi26640441822024225417215314216712714930923631731930120613716020218717215207090800000013395941051029200000044610070000007212987848251000000005116110183106186190100600305358504560779167178129194434001928991211560010170230049271652409909932215015140000000000000000000000000000000000000000000000000000000000000000000000000000000069743640200400007350050000500003556603000030000000000000000000000000000002000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042347170000000000000000203516412699460400000029941694371721404380000000495000001400000000606008200000000000000000000000000000000000000000018090113964000000000000000000000000000000002621674466772723251593245000001900000000026106152210420970000000468210311174100330605044710932990061171145000000000000000000000001229000000004080000000000000000
SP59Bacteria;Bacteroidetes;Flavobacteriia;Flavobacteriales;Flavobacteriaceae;Capnocytophaga;sputigena2232772801412152622132592303572882885766993852318764577969670003200400002322182226142320412316100000000000001215104092215211898000000000300000000000000000000400003000000000000000000000000000000000000203000000000000000000000000000000000000000000120000000000000000000400000000000000020000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000040630000000000000000200000000000000000000000020000000000000000000000000000000000000000000000000000
SP614Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Neisseria;sicca1217389017361418163116000049000000001615112400433514257447761757913487180301270192188124211524751949510723911410475313001210790019627601176196000000000910001717141718120120170140188211314133002400000000000000000010140200122411171703201140011018901201300110000180000000000006005265005300000000392000000001401100000000122000304740271650052421056016000008217400270000400474035072592056600107401494300006270723500350695301186062126460584900447401466105254035370292211191042283270101001193005740527192210130910339709543657051101936515010700005160453756350005151401297644400163310000000490122018363451472785849529400012900000001056305315460000131900240144937628846800015922072000000000000000000000000160000142143002145000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077004200042000000000113000000000000000000000025200000000000000008000425001235600101000000000000000000000000132000000054003712600087002700503100905948
SP62Bacteria;Proteobacteria;Gammaproteobacteria;Pseudomonadales;Moraxellaceae;Acinetobacter;johnsonii000000000000000000000000000000000000000000000000000000000000050000370404000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012050615204192230868614298255243191371881382270090000000000202222331200000014900000501089020022121398640000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001470000001000000000000000030000000000000000000000000000000019000003000000000000000000000000000000000000000000000000000000000000000000000000000004800000000000000000000002000000000037000000006000000000000000000000000030000000000000000000000000000000000000000000000000000000000000000130060000000000040000001800001807000000011
SP63Bacteria;Proteobacteria;Gammaproteobacteria;Enterobacterales;Enterobacteriaceae;Klebsiella;pneumoniae0000000300000003003020004895256233119692902996451995405339468046356342612162221331311854763252781186843727270300042120431010857110239242744236722157992249100031222400506160670000768020275915206813111194807519611370125973025621187495568323736167366026621261215012280881221536534619159425320987026012561145107411300000000110250191865412645165972675741225336722883868291285465498862831000790000285067424433862016558824946614232100474002732357834936372128153665236921962601911583119641936653120150076681416724528833319417929418030410808212192089651519164123216330119121622287750434611401229501622823463460554413782300705300106647754815242642180712186353707226411952003414205509616542409588710167229764222814692246148716307215382009633926303272398611073148550855101301853436251846312863697217920091578431050516261026152370520439105062146622292755229143291044292213747292063036116322737294542719504113460384910014776122822708203143501605921268327417744357135490791181455421318421121111291026311921661800001614233100013620440705200083201967014963291317792559134333327776752141373229171494126393411392139784416427135715672059453206244047040895158867267032482957282860221860793458427562111717697382331113701332233225015347174548517190705300000001631221462800333010801648019381801376821603232234810363011164549282968813152001095107256315179433125961992627196939415033433454941782091521285348764587430451413307637283257853056100719973624676576556624206253271968074732608232762978914511285963981442340505977355907008104802575004233981490035010192168390852600048683799968382679033644357270551605278361081249031097538327340685606816972245543350437062264024371846503196520116128282277340533130431810963052984879965307177715996114142816783049109633161915525828508141022123671506088026794929212009000003424236873937192508618688034120444832947622155485813536511960558957466635632839939502646148956213
SP68Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Neisseria;flavescens23372280275410491905253843483839356152554721417879565283476565167315601454121614941196142111432187202063918801155871430573566802706629926011300274866550861660279023687037754837434540063205310730383877269422592644330279558582491977873432416053303535513232253647835215453036092639230638043712504414593372131722491341769687609664526173906882845764466580448354465137395726112819348057224562429350685660345439283222713854235862384655493407422241472372284123231434590247372961208850777441609844139336685560864867345028663092429494126444487853938698731565275567898311461650856883142397452592650466372544942431151604333644629287338508632163037601497513396055431613515626104423325442288818222632892102547875322966130628767373435535385901255175245578713445265719953999182639974791495726669911071691952436116795285084100002937247157472401757726436265754703361522217243144883111393240351247497611581487257122899332544156717782100116611793022266414181180116320681915165618131885313616221089155519784083124085813711755143916791396150415771403189314431515190117101840195620281292135126031522342040084190260226423363327015703013214656802782275834162429251342321562573733771822174030471405435530274187314824501252377530423678121515301857277315732250176702781007775622228861666392542662896128121173196824110411780412134025118159167549530771235260130642550158135301590483966410155521757223017422017153137755931555431036510042612749080197082344493456703591700177626629301172147810514410226661267204917222090028015822501023556115165348013713071007279818103397510043085899124979399106713082245313619614119616022698581556177220521116897714405122819926372836752922130188956419531703915193254217117117933791316161193659465650100861342099527353195611452640312712982231224296318902544195500000004800000000161500109081068400049014000021278821988139017761782114769301709616900139358024018736814621501598002861293481694120001282611945830231004251422661199108712481059527160287511017216986284244303089170526675533103727692944736722963135702104152082498902799200001394720651419320917269334663815131880353827598176858514828477160915240546646217377357647571033934441179712108699301043574777314042471062790183977823690026290000000004911580635700011012100219414661213124454971071272303115283303033223105338531480575727
SP69Bacteria;Proteobacteria;Gammaproteobacteria;Enterobacterales;Enterobacteriaceae;Raoultella;planticola00000000000000000000000000000000000000000000000000003220012610000000000000021000000000000000000000000000000000000000000000000000130900000000000000000000000000000000000000000000000000000000000000000000000000000022229000000000000000000000000000000000000021502562015350000000214000000650003732770003330000004370029604420000000001216000003552180000740002739000383800000004970933404922105774000001251100000021700005334000204770000007440062401192000000188198027590000042564518183029770000305056000233970002311600000000000000000000000000000000000000000007700028400001148497122746972000051343052207990700009634539105150740000301985923639382000000000000000000000000000000000000000000013300264270000114371244286651600003697191430290990000105048109597266000030001394810411848013210000005732805000000168237740000013436880648240000048870000240122300114900039946480480539300015350009800723133000002640957630000001906401500000254800000000000003312463840001916000413532100043820009460007700
SP70Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;downii24740828323121522022826112117917813123719623722720318920521718124721323000500000000000000000060020472132452200000092048282415030000800061160208172700179000000000080012012091050800000000000000915040000000000301001050020000000000000000000000000000000000000000000000000000000000000000000000000003240000000003335226033374460321042934232862681419342912182736102432432633605917321239281636318750555671847081108623375160841976729341117241622236978113849583143663019838109000000000000000040000000000000000000000000000000000000000000000120000000000000000000000000000000000000000000001100000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009913169748983817200000000000000000000700000044500045703465000800000000012130050050000000000000000000000000000000000080000000000000000000
SP75Bacteria;Saccharibacteria_(TM7);Saccharibacteria_(TM7)_[C-1];Saccharibacteria_(TM7)_[O-1];Saccharibacteria_(TM7)_[F-1];Saccharibacteria_(TM7)_[G-1];bacterium HMT3522404943522582542662353062602152791592732063032783342962983462953112532520060800000009597617110377555856585137272637341327761604018623317617815683126771128230530896490801414160716103040950410101912101616180110131781106111913889139172582071921951104126040901201420712714696005000004000000000900000000003040000324818643001326650200000000000000600000500000000000000423832672132241401391902622161523221012132392122030242813281132181513311916102201723223412920036120534481211246131219151712201722120925013228132162546128000000000200050700000000317232451520003440406400000000000000015020000000000000000000014900000000000000000000035142200000000001000609002000003000000000000000000000000000000000000000000000000000000000000000061020560000000000000000000000000000000082414468566865570000000000030005282778271001800200012035932058030050068001501300182282927371829000000000000000000000000200000400104012230000000000000000
SP76Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;pallens788142810887108307667387734085917775501402100213661248135911691154139413551375109311830000000000004143294441350010600000000000000655886434639161322121220000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000050919000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009571771921000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP77Bacteria;Proteobacteria;Gammaproteobacteria;Pseudomonadales;Pseudomonadaceae;Pseudomonas;nitroreducens000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000090000000000000000034000000000000000000020000000000000000000000000000000000000140000000000000000000000000004000000260000041070002080000000000400000000019
SP79Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;histicola246482440278347256261267314230301300604392579557684488522528756538353543000000020000101951212817131218341005000000000022492631302424258190000000000000000050000000000004054000000000068060110000000000000000000000000300000000000001400000000000000000000000000000000008901205000000000000000000000000000000000000000000000000000000000000000000000000000300000000000000000000000000000000008000000000000000000000000000000000000000000000000000000000000000000000000000000000000700000000000000000000000000000000005000060000000000000000000000000000000000000000030000000000000000000000000000000000039012500000000000000000000000000000000000000350000000000000000100001190000000000000000000000000000000000000150000000000000000000000007000000000000000000000000000
SP8Bacteria;Firmicutes;Bacilli;Bacillales;Gemellaceae;Gemella;morbillorum719181710000000000800000000018726718516527425207700036124830428621924041000006873613150780000002322841221441981132110000019106382518163319938715733512819119113760704815449503740731581501809843891251261861952271411061872056755733618265083200192175113152169207174651188013976128701612051941271802303052151518088161164156115771220004000000000000000438700073022600380017000001900000000000013633700000260000040000000014801007032183427371710022332423451047017022826172114413580172424223420414622423924141219130013036383123221333551718221301831196082224715375718033407528000000000000000000000200000000000006000000000000000000000000000000000000000000000000036301301412614412877180001580028011463251916211032260000163982301911262112128021025262051350016011844181100247107500142214150000000000000000000000000000000000027000000000000000000000000000000000000000000000180331912700432429530000041820000000951190556151470360003002023190937042641200173591512823124010000000000000000000000000000000000000000000000000000000000000
SP80Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;oralis67118749291897510773727353431343415622833529284140469982581258900000019318318714616415769497759525627432517618128833019899004507815134273602661491641781438613484100273158118926594192143220177109147124261145767714261844016770491481069155115532141251811599780109103125115203109130871391121851582181852273442832683272787576473459151129166981514051591565681827531523419029000000000000001212000130000023300253000001020000000000007002570001801825002613900036002480220113250200812252692212591732292883482334231814573202884394151996583364082383544365191811592962811532202864422723652065472412812423403572543242503933284084668476085355401108753918765667321248228310703487624508496455438636383276254201400562505511963500000000000000001310111100152700170009526113556000120700013138004000089286123800558200090005231300000014395457927334198217131017129413028824453437025010584312174649279133001144585329503703127298240539435351826871846231861971571810130672307311431136132112832201971932971271951124311825715517421542421021195126479337000000000000000000000230000000009000836149050000000003000000015000000000000800018600004676072932943935124125350292531533155284118272191166681119262122151668550012146371596627205153551788210336682215915202642363682463733676505629644094524115205421134680214039186810979371510021001524046030000000067007056040000008352124102849239513183298622704500000000000001402011
SP82Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;oralis_subsp._tigurinus_clade_07003200003040404842096410273101101815000000221315202424037100092896935107108172215318043994745583940030000930403617418281926503386233638201230814712131110817252726916102133591531401320112154421715301932541243343131810254525191238232093625191809000000000000000108000000000000000071000000000000000000000980079221490386000000008001221870002151411171261681181631341781602178533220027330818120740425522928743529032681971171216312711219713316411726712614314417420099193188194159200171357216263232386282427385233135147861132812562412672172352873122312431818115328615627532800050000000000604440430810811590000000130140132656003723203800101201410000001971212786930409210080000000114694324909059002391076274792005044669954555117159117290795604283392672724456125667290400170172812811284000930000007264352822314357202131264538571459032927112473936012215256230464855114863551742899958165394550000000000000000000000000000000000035800000000000000000000000000000000000000002085001211752472812472581771445700183311702436418360809573432008160192241361283950963890935178226201149185292112843751051256311716839281513293583655253602880231604800000000002000000000000000000156611002102700000000000000000
SP84Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Aggregatibacter;aphrophilus2038383730296370264350332215160151470645729342897510358188331694714390126751435070925829031627725331521014313344018293100125177141135589250401589712139141167987251129546808275631062971627419332481180537266112511652832120283510482962662065602883362481768571174873836687371431288590713618757836460337615438513594535858105670267083888595890410758287831106449657442847719923106886391112419378149001404155115314134145915801083767875916726130811704876743492632530000003000001960043200714012337658501849697703546541459346766686984433601100114040115409800028127008800000200107870145991062111512498414459260632236841163514629316014754571285718819611920810710719314812918712616098121345295189232119134245529581111434517830482337835315012162560148102194427389318313967693572611232288836235215910517713923811722600000670000008601620030000000250127961097735328736712487138211392000000000032300000000000000000400000521576259364100000000521560501125822155464466813474147763791782616151422667634050539575047229900000000191030905000000000110168000000001901210144614690000000700000000070000000770000002907374891289577104711562630000000000000000000000000000000029118418823367267342656300000000000300004621178862901301445407271240276769837300006000000000002582112364781118117183315660000000000000000000000004140000110042014477888110000000000000000
SP85Bacteria;Proteobacteria;Gammaproteobacteria;Enterobacterales;Enterobacteriaceae;Enterobacter;kobei000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002060123000000000000958000000000247000000000000000000039000650000000000000000001000000000460029700000000000011227000000000241500000000000000000006500083500006000000070000000120000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002000000000000100000000000000000000000000000000000000000000001000000000001000
SP88Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;parasanguinis_clade_4113185284982624063762191921972012382585013464994203883592163132443133252781702581492223122360000005354374948560000003434743722822543690000006211964857252000000515434681598456580642369566101470310834951058105186941058243850248846948752564079475378785165899083653673969682590177988669930128039343042654760650077575690648594411059911045505456528611622657716550688624387561122035112061233555501358515650639510820047000060000000008901600001485145902915871219176250180181412720320000000003700735000048074190014045901400000364301101054354404194554564975064994955563244857416699677193994935232594926426305153132653784735654824965744885944085665798227088865614554196563734664104421150814948109312381124115210776964184165213938056115289169571022105010091018657769400501655647779577000000000000000000050140000000006119131926000000000004000246000000080015630000000000000000623000382938630571000021981313960000006120608179249152551000000611648749385407533304583123341240514903345499991363101362311811560000281632012661311619283176371601632200016353430000000000000000000000000000000001161277176172111161000000000000000000000000000000001034780617622975689760491537707342136185814192947739585245235104166432011066088003000001021123174284401981078010746011748116170947195580351210091400000000000000000130000000000000000004504400000000000000000
SP89Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;salivarius14292356218012381707166198481372987310408742454200027532434242523871571182315972139162916507761643112110561772135120718720040963817515615014317816300000040694902407637043454441222610916630421798526747466473361257073005161811911459172819812726249015971944437143964871307648975798318320084490184237603778379136402622115712051323129712631320185316911621131518771440150415011337124018882403265722751878296628622537338843593346228340993351364730923528328430673134213023923343225539653628326328164151248542913415281737852803383129753545275528801544531892047590377250037180513448138394981955211413434267208321452880523029582161300021199493385231322479449211381216242151002647933975013661171108654712134712712512825521141735774068390670178201315748314781143350267125133707445138654044477027076037686644645690596859959067899831843762558524325040485971625457296819042201290130032567234426512552305619682354239927872798285140843523273948012152279127262500664556636091631565225781589865015809412841274793346852306394396954158786606655756604495873768524892246985277410668345196254291175347718747328501300076048874218116347412193065510641800312067773110530846271913943052622311662081561570065151219181215351663546224220957609014100864253015638042140134917128100069114013571190000020244979631000026472272518080016014900000049986541164185187764910691355906650212621024103211622201115170276043018371451112145781735085241220105586173135772531252636112028820826711900004855805170000008110000600100000000000000018184356497724487307367624460716300109001700077900000003100015000100746921733376138803936304348843670360530612641853384568213242929647488014451444510728461030227582249151736100130112661420152846574760468848126467220455481362591624771731888220365027456255148015910112494147765002224426445752392210701184658097706011480561321600000000095600002759813662056252527461261101981180327213331451604432
SP9Bacteria;Firmicutes;Erysipelotrichia;Erysipelotrichales;Erysipelotrichaceae;Solobacterium;moorei285449334232317257147981261411881362171651772051791348396921036977830141027310000001741471171342161130033036198705248550000002083542651651631370130040889311220221713242578186147405121118209191033113633452445348271633313431261827203514213138414761396063426310262219102021292924746391242292623629221402400000000000000000000000015540000005200000000000000000100000500000000023003000005000005657524634173124171519181230272141410703411124911176781618242191411221455126216161110219012111851105090126154639511850069000000000000000000000000000000000760000000000000000000000000000000000000000000000000141333250000059000020000760011222176119000622407235340103949117600000001770000001920003006012303000000000000000000000000000000000000000000000000770000000000000000000000000000000012694155174891621311325000003000003030017220316512112180617202006066121146701096113101013017257684341175103600300200000000000000000000000002125000000000020000000000000000
SP90Bacteria;Firmicutes;Negativicutes;Veillonellales;Veillonellaceae;Veillonella;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
SP94Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Neisseria;perflava28683414418617413184346761915327559459347221680018901493218217631846133536413666318539182973378813851399870111717471021118489261059610496823120270731482770375127201970266626682182186519691896179814531284166519039738241026105288876653758070519955034169340891407277758660763774395952246748233626136319416710963047156919321907188516861807212515041662104111887885117251467138619061757154197312719422513178018691701165411651275105717816741420127730247230277710859141224103211841126113585058467391918299551018113015838451769777108818081296956565640905742100297291778975056276874562543476644200037649143616402220711349697111715281082963651273123207992841237640340828341233215480279023293637480128621568279351335300288746348427001603231322004244196424117847306115081440234052808700561061842138060112013012126812487740861137378481321601713160316741889248829451740126225881690136417311930218725723088110117331945191321271711165421252151165815891793267822162192155110777898141496102021721097312927502171278814561509192820596116385526063675191713775133213453483531980981427017433567377045713242279812565050434819241065152112412124160420411519000076712020660131991335196919509701245624025340072159048167414853126420424814511883663173622212471161916361019155311512582127902240210700413422185395623990238171138555277000267620483109446711037618004235717824959600039152117167000006400516403606279339623205716128773813512043223821535337424767999615131868162147132939613115414316013470780000000026320900001100000000014426196211560001440000285151222000000000000000000033555026430042000000111176199171154224117880000000000000000000000000000000014423728638216036537217100000000000133039182317577928453564132210655544340712345463779443621687499119642674447656950001122723820000473237423879363832581394384161810840000000000000002590000000994481000036235108347847272698900042000000000000
SP95Bacteria;Actinobacteria;Actinomycetia;Actinomycetales;Actinomycetaceae;Actinomyces;sp. HMT16951141116667172831073951807479911178679711081185393921126231354300000023161595160000000146600000000011203500000000030610002203859215556411710171581078122191417024210151522824101140117080313162413143530251260151618262018252811312923191150812161817000000000000000000000000000000000270000000000000008000000000600000500000000000034000131091310816357351128324422615891465104214710101041200041351001510191201931411241650482726159193424322120302252291301621183433000000000000000002000000000000000000000000000000000000000000000000000000000000001642450017146100002025581120970120701415260273596940197000051321216912117075000016000305400500000368400001164000000000000000000000000000000000000000000000900000000000000000000000000000000733126223947342610150400133302001162202652211147210500000001002836173780122816003115523303727110000000200000000000000000000000000000000060000000000000000000
SP97Bacteria;Proteobacteria;Gammaproteobacteria;Enterobacterales;Yersiniaceae;Serratia;marcescens0000000000000000000000000000000000000000000000000000000000000000000000002380000000000000000000000000810000000000000000000000000000000000000000000000000000045700000000000000000000000006806000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000120000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000090184000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SP99Bacteria;Firmicutes;Bacilli;Lactobacillales;Carnobacteriaceae;Granulicatella;elegans51105477653692951182730918171223191721231329100145317216123001000055222525333000400014161951416000000234516311913000000372865433523302768834379353650494140100608262632303322262124143023192120933262035303358461737191870516757064000013102001023292424006010301006000000000000000000000000000002441200000000000000000000000000000000000000000000000018161715117130000660700600000000100080085060091070000180231316181417015000000009000000060009800000000000000000000000000000000000000000000000000000001500000000000000000000000090007101700000005000000000000000000000000061312600070000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000700004000000000000000000560000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SPN106Bacteria;Proteobacteria;Gammaproteobacteria;Enterobacterales;Enterobacteriaceae;Enterobacter;mori_nov_97.951%0000000000000000000000000000000000000000000000000000333001171000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001600000000001626000002160000000000000000033000073000000000063105612471646300001139499300036701049158957200101900691589946060100540000004221000001985000000000000000001606000019400000000004776032005532330029240000478450582466683149300067555469483967704607004625532144560000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055800002380045502927235927676250744007441410741083634628893800119149195302356700000078314200004680007748707208851027425057228060914212860365335305166021600718005681251626113103528611170063004215658546195278957003107733983245161000000038010000805000152421859861268041696251429066314992010652569467
SPN148Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Prevotella;sp. HMT305 nov_93.865%142245186104139112169208911442001321771181421771811481892422392041882090000000000003932322633294989050000000000007610141067000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000608000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SPN15Bacteria;Proteobacteria;Epsilonproteobacteria;Campylobacterales;Campylobacteraceae;Campylobacter;concisus_nov_96.963%223423171919262515263522071181401520141216155155588781594635453031338778308817601040727661808790677587567546946372685345172620117101055679662576511115810849071057512600283144525378596416342410839123459212441544285836314511089113961161431422167721901011561151305574597642425284414940723322445725331434102013284065123423106558353738328282241152722153223716100000000000321030008540100343749000300080323243401237025000000000400000005000000000000006584617434542728392124292124433749531811141501255372100254124187711983801827556782154003011363750417430305000121501131400123070129112443122141011150000171300009014952040240000001815802010080801302600000002400000000000000000000000000014039153100000000070000000002370401921111231078110611232022124446490000000050000050000000000000080000000147110000000000000000000000000000000001415377492342000000000000000000000000000000008819827555894722000000000000000011450592159490640050082202550303351103800000650170361121453250786564543900000000000000000000000051000000056117540006050002401300032
SPN189Bacteria;Actinobacteria;Actinomycetia;Micrococcales;Microbacteriaceae;Microbacterium;barkeri_nov_96.996%0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062390000000000000000000000000
SPN211Bacteria;Bacteroidota;Cytophagia;Cytophagales;Hymenobacteraceae;Siccationidurans;metalli_nov_95.798%0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511300000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SPN248Bacteria;Proteobacteria;Betaproteobacteria;Neisseriales;Neisseriaceae;Neisseria;sp. HMT020 nov_94.070%00000000000000405015116107706103124003000104271414272461251723021352325222791415151511367262242219212126698313324276152156405000600000000100000000036060000000000000000310710000000350000000000003000000000000530000000000000000000000000000000000000000055500000000000000000000000000000000061343520314516200000040000000000756612622500612206040602999183313526612500040000000040000000000000593918182941181200000450000000135000300000000023040215852389217221662000000000000000000000000000000000000000000000000000000000000003500000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044000000000000000000587201510390120000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SPN370Bacteria;Fusobacteria;Fusobacteriia;Fusobacteriales;Leptotrichiaceae;Leptotrichia;sp. HMT215 nov_96.963%261255238971852798102541846321547406051431270021000000018000000026152820281800000000000000000000000000000000000000000000000000000003134004443000002148273005144640000394640790210029263645000043884114500004140306500213700000000000000000000000000026800152666000000000000000004000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004000000000002900000000002730030098690000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SPN424Bacteria;Saccharibacteria_(TM7);Saccharibacteria_(TM7)_[C-1];Saccharibacteria_(TM7)_[O-1];Saccharibacteria_(TM7)_[F-2];Saccharibacteria_(TM7)_[G-5];bacterium HMT356 nov_93.409%00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029778000000033000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SPN447Bacteria;Proteobacteria;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Haemophilus;haemolyticus_nov_97.947%174029191421325623223321128434315846169163533211135507504115174152781197272386688451050231107000000261861931205020030121248643602577713618381643101319131515417113862038507157001034147721131824911121981110131387163524925813282202411005505070000000030000000213000000000000000000600901000000000005000000000000000000000000000000000000001000000000600021246001020000000000000000000000000000000000000000210200000000000000300000000000060000005000020000000000000000000000000000000000000003800000000000000000007000000000000010913040400000000000000000000000000020000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SPN62Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;sanguinis_nov_97.782%43810600110050000000000000611115101303000001060100000000460596000000016054000000022231917151716122922383432383225415128323620371429202620201112941232423281516101413142027248111530212116362732161420157191992210171042193946161020192091612000000000000000013400000000000000090000000000000003000000070000611000060127000019000753100812011262815281910262227152224222121191072710107211213155351212135195589712142316161438817171614812121914241916232320901213111716162300000000000000000000000000000000000000000000000000000000000000413000000000000000020714207273634152000000300000000000004065040000004249436434333776000000000000000000000000030000000000470300000000000000000000000000000000671411501200000000000000000000000000000000016261418302412130000000000000632116006094015000000403722321600000000000000040000000000000000000000100000000000000030000000000000000000000
SPN70Bacteria;Bacteroidetes;Bacteroidia;Bacteroidales;Prevotellaceae;Alloprevotella;sp. HMT473 nov_97.347%5049467184574884446097153765506384275323564804074403535435774625744884920000000000001521131051221587935407248462000000000000000000098000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826995400000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000700700000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SPP10Bacteria;Firmicutes;Clostridia;Eubacteriales;Lachnospiraceae;Oribacterium;multispecies_spp10_2225444324186263236113761601431201003022464433733804041201461669110313200000000000037212144463700000000000000000024353442182800000000030000000000000000000000000000000000040000000000000000000000000200000000000000000000000000000000000000000000000000000000000000000000000005000000000000000000000000000000000000000000000000000000000000000000000000000000000000020000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000040009091300000000006043001000018049360005000252200303715932002000515000000000000000102000304000000000000000000000000000000000000000000000000000000000000000000000000000000003447881200005000000000000000023082210110170000000009100000050023006502280000000000000000000000000000000000000000000000000000000000000
SPP14Bacteria;Proteobacteria;Gammaproteobacteria;Pseudomonadales;Pseudomonadaceae;Pseudomonas;multispecies_spp14_20000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018700000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000300000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153000112600032000000000000000000000000000170000000000000000000000000000000000000000000000000000000000000000000000004000000000000000000033000000000003000000000100000000013010000000000037
SPP18Bacteria;Firmicutes;Bacilli;Bacillales;Staphylococcaceae;Staphylococcus;multispecies_spp18_3200000200000000000000000221816050290300000502000000044012080000000001600000000139390500112075837945601523511661004102551911177118013637193101704133004126967935149746380152523402547234144321177102492181593179918578815200000000006514703400221231072840010000007290005170000000000000147690351617007748913410352606712315614205102631115140043721515656107252209944000000000000003700056720070130050000020504670000000250000000201280000020100000606916000000000000000001900015378000000000000000000000000000002630000001920000002400011000000254000000000200000679687312000000000000000000000000004014130016213323281711064923090710113162478782330048160166341012501411630000000001300160200000000000000000000000000000000000000316003162801202200546950086045416100040330460000032125781820411022029077941555000500000000000000000052666000400011600760000000000000000130005000673000000003000000000000004350001000000000
SPP24Bacteria;Proteobacteria;Gammaproteobacteria;Enterobacterales;Enterobacteriaceae;Citrobacter;multispecies_spp24_2000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003100000000000000000000000000000000000000000000000000000000000000000000000000000957000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056163650000005467139000000013240700000000000000000000000000000000000000004344911000000914655100000000000000000000000000000000000000
SPP25Bacteria;Firmicutes;Negativicutes;Veillonellales;Veillonellaceae;Veillonella;multispecies_spp25_2257446314197180199490714287386435313335273388323314308602576487570477546337163744270436567205661105261251196481288613593145133375289535732962431233434880501948554207334623378458894576535513683576521330910838101251444910410110712524434931432445255219545778618760304010299736639605782292848218754069878206515016423039396855682993661842065376606451953975567244564789518552856491676592099421754063809413866572967793779810686681769067128676059707083695173028393900186637545199915883006181315372135265123963832424847185584664864307698757757354615531435564293570146574887432853475509502675166982717465865330104766537753854575116804976910347680139001322918831188762121114035102687610054731867313322696091504461315301303426978710823217962310317884426711772895208798137871081258049355767370671013953051079508376312792698111311330732443100161163393444946101108128371616813768621851552163821946390877895852568566715771978047048985210404751711376888283397579839266291012991374185508765027010527290926930918386367800699676447733810777267246897154046961775087659871797661979413760872657797786519221598161219165534559849675110792874634870497610149159439812843217993754783481904768719561657628529151071277810422104801310121273127877532104071128287391281210361475810582393219870683871167843272852633078083815619232045473365318357482131611541332645179592829240103617154760494721030110379804981676714825264867278662360761991006119686912351619226411952211001498804865511969692437180527020401592905525218790203186421455700713328113899747050000300185714341560688943209367191738742366285336184118472779217545127531843278343317314615612368318400790164097774913663158090000000853694854132159306145432119170400702252022694662439342946117433623174446301776684818978167861371100000017263007200060379800217074280046001200761008990118391794612248990714938107951131200000001600000004900000008048500171015194321641297641448211451138621069511592003429000057618113110156126524747987505270123694805392114738214774582632526327721411453143251054513621752852481146412895180655021103505912134293864965229312928914655302522305624801182802398700000000002240240185800500010671608011721000104802513146462546322474290385582592140125230034510524241368319153
SPP29Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;multispecies_spp29_29051263136957310639911119869874970127110405804836686745765095455815877075615540015040150000007677655989540000003469274430420000002423411231821521290009001519201618182219461368415095931609430140418948138224539719745384446302365413962466876586944282624211618540102469467189184107131145117195183421882661557350764410965111126252195111119125210532430000000000000000732201441796715346000000158005208220100000000000080048200850136306185283731124010047000077018037334002593928222434574237874655102138901391921123511241222492593494070382053287304878765368688886724136215233202425160165891169911586106196184155200214390445326149121100107937314732711414813830323812200000000000000001573415455152010500000000416415780000000000000164008000034291310171101510000000032273100278000000019000004060040000000053200040000040000250011130000770000000000000000000000020000000000000000000000000000000000000000000000000000000000000000000000000000000000011001002111180000037000000080120072112000000037001517900070000011078000000000000000000000000000000000000000000000000000000000000000
SPP31Bacteria;Actinobacteria;Actinomycetia;Corynebacteriales;Mycobacteriaceae;Mycolicibacterium;multispecies_spp31_20000000000000000000000000000000000000000003000030000000000000000000004000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000160000300200000243000002890011830001000000000000043000000000002000000650000400000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003000000000000000000000000000000000000000000000000002500000000000000000000000000000000000000002000000000000000000000000000000000000000000000000000000000000000000000000000004405000000000000000000000000000001100000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032000000000000008000300001200
SPP34Bacteria;Proteobacteria;Gammaproteobacteria;Enterobacterales;Yersiniaceae;Serratia;multispecies_spp34_2000000000000000000000000000000000000000000000000000000000000000000000000203000000000000000000000000069000000000000000000000000000000000000000000000000000004240000000000000000000000000697500000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SPP35Bacteria;Proteobacteria;Gammaproteobacteria;Enterobacterales;Enterobacteriaceae;Raoultella;multispecies_spp35_20000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000010650000000000000000000000000000000000000000000000000000000000000000000000000000001794900000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000079000205000010084157195760580000442371718878529000078038928604240000025357235293787900000000000000000000000000000000000000000001330094270000946547833355725000035959713435757800008644223714619800002330113952279947000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SPP37Bacteria;Proteobacteria;Gammaproteobacteria;Enterobacterales;Yersiniaceae;Serratia;multispecies_spp37_2000000000000000000000000000000000000000000000000000000000000000000000000410000000000000000000000000013200000000000000000000000000000000000000000000000000000893000000000000000000000000016920000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000700000000000000000000000000000000000000000000000000000000000000000000000000003000000000000000000000000000000000000000000000000000000000000000000000000000000007820012720003650000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000
SPP53Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;multispecies_spp53_2143245182132133141595050465744212191256218243298699989109989348577159790311827150003201391221339714015500000014561968164614921276185093100902605382653212651960000002500184615752420188724933007162112423758297348721762516049513493867171680721911705142113571411243834572475310434032919480741432212828220239613961413344953190126111551631196614682217269520403212386840162641412638814333487919262218211127451912202129862348269832681096298142062475699488426202169107325702501275219603209097570020130009024530045026933113062989705631182981211618290147512530110169123040000011685306082451701321873561590416152520306640600001759329014364209020912509273924272555322117272531153817732221313627074033262514081745198884215571913246216321604146412792238237520751919184827963293254827063154402538603758241119351837278814671648181913274748371943734528433036043531449221041596143616611101233220221975349335662987364627233765217335911498135015141967222513690000000700003400006772800016501400600106304601007000000624002223002840123767002560170000038150500000210000829683565000008043800024219000241077301831717802550001003556081036569408745758597182200000144646906916241635400131602212162325701330000002621000000000000000000000000000000001003721001610000000000000000000000000000000021921773164815621385157714761089130031264026112339304739133349795192201148849429115501880000000518512352140117483536615582613875558121019467101229381218233391600000017000000000000000000000000000000002485900000000000000000
SPP6Bacteria;Firmicutes;Negativicutes;Veillonellales;Veillonellaceae;Veillonella;multispecies_spp6_324133629817621918736043224937843433442330943743844334465465258271453067312529521123727124736857044755655852447934346840845535759656873364453035124038730028825221744640758566749838962498668954046432716061268109387460455017518729727231733333832023825920841725650251242716423112035626142732032126331732036138442354851611322220835933732936929432434838541332136744633029720521512520126220918028422433020332828336029949628630126129427233027622326836024631130533634517624911314920414433246000347206362218892860363106214109833051731460026001352719722282863388499225495139244154849520948327426202260012802013720203234134240277952031645021520961039039143128006214296324822723921921222334019333735225326058632443640519029340813831635545536920620927633935327727122917818215520719728829821024320523221316519919416637812820317442322816924232325118119716026317818120323023721137113424435211517934423118629959831422733728321158528079122116278094952293816499347229515425345534050701710823060451946053437358335064233822431718422930130420031344407850049630054732305217201041314321774045212218001520004116101435255172121000000001251006995782447513217914615422041266272479546146135125170007911217983981421171170300000060599355637980000000004207982535356057514002433124519900000000000000000692000014005480000001091983792091442182132070000000000000000000000000000000017316817717516114718015800000000171900300521355788028237173239735532000031042182641311651620000788946101000022112772411372051722503612543273240000000000000000000000015717400005203763372392763020000000000000000
SPPN11Bacteria;Firmicutes;Bacilli;Lactobacillales;Streptococcaceae;Streptococcus;multispecies_sppn11_2_nov_97.976%6799132561019811682788410297723960724245444351524040000660000000267190352100000010705011000030244627534020000000000000000300035041001260466000008003065000000000500120812724000120523029000030011179070160700000000000000000000120000000000000003320000000000000000000000000012200000000000000004403500000017171130180331625224429476891595062019204714150000570062771711101511422316342974759221221408827599134467571400000000000000000009000300000000000000000000000000000000000240131412000000000116000000000000000000000116000000000052029300000000000000000000000000000000000000000000700000000000000000000000000000000000000000000000000000000000000000000000000000000000000400400000004000000000393600121506009003205000000000000016000000000000000000000000000000000000000000000000000000000000000000
 
 
Download OTU Tables at Different Taxonomy Levels
PhylumCount*: Relative**: CLR***:
ClassCount*: Relative**: CLR***:
OrderCount*: Relative**: CLR***:
FamilyCount*: Relative**: CLR***:
GenusCount*: Relative**: CLR***:
SpeciesCount*: Relative**: CLR***:
* Read count
** Relative abundance (count/total sample count)
*** Centered log ratio transformed abundance
;
 
The species listed in the table has full taxonomy and a dynamically assigned species ID specific to this report. When some reads match with the reference sequences of more than one species equally (i.e., same percent identiy and alignmnet coverage), they can't be assigned to a particular species. Instead, they are assigned to multiple species with the species notaton "s__multispecies_spp2_2". In this notation, spp2 is the dynamic ID assigned to these reads that hit multiple sequences and the "_2" at the end of the notation means there are two species in the spp2.

You can look up which species are included in the multi-species assignment, in this table below:
 
 
 
 
Another type of notation is "s__multispecies_sppn2_2", in which the "n" in the sppn2 means it's a potential novel species because all the reads in this species have < 98% idenity to any of the reference sequences. They were grouped together based on de novo OTU clustering at 98% identity cutoff. And then a representative sequence was chosed to BLASTN search against the reference database to find the closest match (but will still be < 98%). This representative sequence also matched equally to more than one species, hence the "spp" was given in the label.
 
 

Taxonomy Bar Plots for All Samples

 
 

Taxonomy Bar Plots for Individual Comparison Groups

 
 
Comparison No.Comparison NameFamiliesGeneraSpecies
Comparison 1SALIVA Pool 1 PMA+ vs SALIVA Pool 2 PMA+PDFSVGPDFSVGPDFSVG
Comparison 2SALIVA Pool 1 PMA- vs SALIVA Pool 2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 3SALIVA Pool 1 PMA+ vs SALIVA Pool 1 PMA-PDFSVGPDFSVGPDFSVG
Comparison 4SALIVA Pool 2 PMA+ vs SALIVA Pool 2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 5SST Saliva P1 PMA+ vs SST Baseline P1 PMA+PDFSVGPDFSVGPDFSVG
Comparison 6SST Saliva P2 PMA+ vs SST Baseline P2 PMA+PDFSVGPDFSVGPDFSVG
Comparison 7SST Saliva P1 PMA- vs SST Baseline P1 PMA-PDFSVGPDFSVGPDFSVG
Comparison 8SST Saliva P2 PMA- vs SST Baseline P2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 9SST Saliva PMA+ vs SST Baseline PMA+PDFSVGPDFSVGPDFSVG
Comparison 10SST Saliva PMA- vs SST Baseline PMA-PDFSVGPDFSVGPDFSVG
Comparison 11SST Baseline PMA+ vs SST Baseline PMA-PDFSVGPDFSVGPDFSVG
Comparison 12SST Baseline P1 PMA+ vs SST Baseline P2 PMA+PDFSVGPDFSVGPDFSVG
Comparison 13SST Baseline P1 PMA- vs SST Baseline P2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 14SST Baseline PMA+ vs SST Final A PMA+PDFSVGPDFSVGPDFSVG
Comparison 15SST Baseline PMA+ vs SST Final B PMA+PDFSVGPDFSVGPDFSVG
Comparison 16SST Baseline PMA+ vs SST Final C PMA+PDFSVGPDFSVGPDFSVG
Comparison 17SST Baseline PMA+ vs SST Final D PMA+PDFSVGPDFSVGPDFSVG
Comparison 18SST Baseline PMA+ vs SST Final E PMA+PDFSVGPDFSVGPDFSVG
Comparison 19SST Baseline PMA+ vs SST Final F PMA+PDFSVGPDFSVGPDFSVG
Comparison 20SST Baseline PMA+ vs SST Final G PMA+PDFSVGPDFSVGPDFSVG
Comparison 21SST Baseline PMA+ vs SST Final H PMA+PDFSVGPDFSVGPDFSVG
Comparison 22SST Baseline PMA+ vs SST Final I PMA+PDFSVGPDFSVGPDFSVG
Comparison 23SST Baseline PMA+ vs SST Final J PMA+PDFSVGPDFSVGPDFSVG
Comparison 24SST Final A PMA+ vs SST Final A PMA-PDFSVGPDFSVGPDFSVG
Comparison 25SST Final B PMA+ vs SST Final B PMA-PDFSVGPDFSVGPDFSVG
Comparison 26SST Final C PMA+ vs SST Final C PMA-PDFSVGPDFSVGPDFSVG
Comparison 27SST Final D PMA+ vs SST Final D PMA-PDFSVGPDFSVGPDFSVG
Comparison 28SST Final E PMA+ vs SST Final E PMA-PDFSVGPDFSVGPDFSVG
Comparison 29SST Final F PMA+ vs SST Final F PMA-PDFSVGPDFSVGPDFSVG
Comparison 30SST Final G PMA+ vs SST Final G PMA-PDFSVGPDFSVGPDFSVG
Comparison 31SST Final H PMA+ vs SST Final H PMA-PDFSVGPDFSVGPDFSVG
Comparison 32SST Final I PMA+ vs SST Final I PMA-PDFSVGPDFSVGPDFSVG
Comparison 33SST Final J PMA+ vs SST Final J PMA-PDFSVGPDFSVGPDFSVG
Comparison 34SST Baseline PMA- vs SST Final A PMA-PDFSVGPDFSVGPDFSVG
Comparison 35SST Baseline PMA- vs SST Final B PMA-PDFSVGPDFSVGPDFSVG
Comparison 36SST Baseline PMA- vs SST Final C PMA-PDFSVGPDFSVGPDFSVG
Comparison 37SST Baseline PMA- vs SST Final D PMA-PDFSVGPDFSVGPDFSVG
Comparison 38SST Baseline PMA- vs SST Final E PMA-PDFSVGPDFSVGPDFSVG
Comparison 39SST Baseline PMA- vs SST Final F PMA-PDFSVGPDFSVGPDFSVG
Comparison 40SST Baseline PMA- vs SST Final G PMA-PDFSVGPDFSVGPDFSVG
Comparison 41SST Baseline PMA- vs SST Final H PMA-PDFSVGPDFSVGPDFSVG
Comparison 42SST Baseline PMA- vs SST Final I PMA-PDFSVGPDFSVGPDFSVG
Comparison 43SST Baseline PMA- vs SST Final J PMA-PDFSVGPDFSVGPDFSVG
Comparison 44SST B Final PMA+ vs SST A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 45SST C Final PMA+ vs SST A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 46SST D Final PMA+ vs SST A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 47SST E Final PMA+ vs SST A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 48SST G Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 49SST H Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 50SST I Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 51SST J Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 52SST D Final PMA+ vs SST B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 53SST E Final PMA+ vs SST B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 54SST G Final PMA+ vs SST B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 55SST I Final PMA+ vs SST B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 56SST D Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 57SST E Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 58SST G Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 59SST I Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 60SST D Final PMA+ vs SST E Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 61SST H Final PMA+ vs SST J Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 62SST J Final PMA+ vs SST G Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 63SST I Final PMA+ vs SST G Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 64SST B Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 65SST A Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 66SST A Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST D Final PMA+ vs SST E Final PMA+ vs SST F Final PMA+ vs SST G Final PMA+ vs SST H Final PMA+ vs SST I Final PMA+ vs SST J Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 67SST A Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST D Final PMA+ vs SST E Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 68SST F Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST G Final PMA+ vs SST I Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 69SST B Final PMA- vs SST A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 70SST C Final PMA- vs SST A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 71SST D Final PMA- vs SST A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 72SST E Final PMA- vs SST A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 73SST G Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 74SST H Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 75SST I Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 76SST J Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 77SST D Final PMA- vs SST B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 78SST E Final PMA- vs SST B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 79SST G Final PMA- vs SST B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 80SST I Final PMA- vs SST B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 81SST D Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 82SST E Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 83SST G Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 84SST I Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 85SST D Final PMA- vs SST E Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 86SST H Final PMA- vs SST J Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 87SST J Final PMA- vs SST G Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 88SST I Final PMA- vs SST G Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 89SST B Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 90SST A Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 91SST A Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST D Final PMA- vs SST E Final PMA- vs SST F Final PMA- vs SST G Final PMA- vs SST H Final PMA- vs SST I Final PMA- vs SST J Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 92SST A Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST D Final PMA- vs SST E Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 93SST F Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST G Final PMA- vs SST I Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 94SMT Saliva P1 PMA+ vs SMT Baseline P1 PMA+PDFSVGPDFSVGPDFSVG
Comparison 95SMT Saliva P2 PMA+ vs SMT Baseline P2 PMA+PDFSVGPDFSVGPDFSVG
Comparison 96SMT Saliva P1 PMA- vs SMT Baseline P1 PMA-PDFSVGPDFSVGPDFSVG
Comparison 97SMT Saliva P2 PMA- vs SMT Baseline P2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 98SMT Saliva PMA+ vs SMT Baseline PMA+PDFSVGPDFSVGPDFSVG
Comparison 99SMT Saliva PMA- vs SMT Baseline PMA-PDFSVGPDFSVGPDFSVG
Comparison 100SMT Baseline PMA+ vs SMT Baseline PMA-PDFSVGPDFSVGPDFSVG
Comparison 101SMT Baseline P1 PMA+ vs SMT Baseline P2 PMA+PDFSVGPDFSVGPDFSVG
Comparison 102SMT Baseline P1 PMA- vs SMT Baseline P2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 103SMT Baseline PMA+ vs SMT Final A PMA+PDFSVGPDFSVGPDFSVG
Comparison 104SMT Baseline PMA+ vs SMT Final B PMA+PDFSVGPDFSVGPDFSVG
Comparison 105SMT Baseline PMA+ vs SMT Final C PMA+PDFSVGPDFSVGPDFSVG
Comparison 106SMT Baseline PMA+ vs SMT Final D PMA+PDFSVGPDFSVGPDFSVG
Comparison 107SMT Baseline PMA+ vs SMT Final E PMA+PDFSVGPDFSVGPDFSVG
Comparison 108SMT Baseline PMA+ vs SMT Final F PMA+PDFSVGPDFSVGPDFSVG
Comparison 109SMT Baseline PMA+ vs SMT Final G PMA+PDFSVGPDFSVGPDFSVG
Comparison 110SMT Baseline PMA+ vs SMT Final H PMA+PDFSVGPDFSVGPDFSVG
Comparison 111SMT Baseline PMA+ vs SMT Final I PMA+PDFSVGPDFSVGPDFSVG
Comparison 112SMT Baseline PMA+ vs SMT Final J PMA+PDFSVGPDFSVGPDFSVG
Comparison 113SMT Final A PMA+ vs SMT Final A PMA-PDFSVGPDFSVGPDFSVG
Comparison 114SMT Final B PMA+ vs SMT Final B PMA-PDFSVGPDFSVGPDFSVG
Comparison 115SMT Final C PMA+ vs SMT Final C PMA-PDFSVGPDFSVGPDFSVG
Comparison 116SMT Final D PMA+ vs SMT Final D PMA-PDFSVGPDFSVGPDFSVG
Comparison 117SMT Final E PMA+ vs SMT Final E PMA-PDFSVGPDFSVGPDFSVG
Comparison 118SMT Final F PMA+ vs SMT Final F PMA-PDFSVGPDFSVGPDFSVG
Comparison 119SMT Final G PMA+ vs SMT Final G PMA-PDFSVGPDFSVGPDFSVG
Comparison 120SMT Final H PMA+ vs SMT Final H PMA-PDFSVGPDFSVGPDFSVG
Comparison 121SMT Final I PMA+ vs SMT Final I PMA-PDFSVGPDFSVGPDFSVG
Comparison 122SMT Final J PMA+ vs SMT Final J PMA-PDFSVGPDFSVGPDFSVG
Comparison 123SMT Baseline PMA- vs SMT Final A PMA-PDFSVGPDFSVGPDFSVG
Comparison 124SMT Baseline PMA- vs SMT Final B PMA-PDFSVGPDFSVGPDFSVG
Comparison 125SMT Baseline PMA- vs SMT Final C PMA-PDFSVGPDFSVGPDFSVG
Comparison 126SMT Baseline PMA- vs SMT Final D PMA-PDFSVGPDFSVGPDFSVG
Comparison 127SMT Baseline PMA- vs SMT Final E PMA-PDFSVGPDFSVGPDFSVG
Comparison 128SMT Baseline PMA- vs SMT Final F PMA-PDFSVGPDFSVGPDFSVG
Comparison 129SMT Baseline PMA- vs SMT Final G PMA-PDFSVGPDFSVGPDFSVG
Comparison 130SMT Baseline PMA- vs SMT Final H PMA-PDFSVGPDFSVGPDFSVG
Comparison 131SMT Baseline PMA- vs SMT Final I PMA-PDFSVGPDFSVGPDFSVG
Comparison 132SMT Baseline PMA- vs SMT Final J PMA-PDFSVGPDFSVGPDFSVG
Comparison 133SMT B Final PMA+ vs SMT A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 134SMT C Final PMA+ vs SMT A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 135SMT D Final PMA+ vs SMT A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 136SMT E Final PMA+ vs SMT A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 137SMT G Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 138SMT H Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 139SMT I Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 140SMT J Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 141SMT D Final PMA+ vs SMT B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 142SMT E Final PMA+ vs SMT B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 143SMT G Final PMA+ vs SMT B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 144SMT I Final PMA+ vs SMT B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 145SMT D Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 146SMT E Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 147SMT G Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 148SMT I Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 149SMT D Final PMA+ vs SMT E Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 150SMT H Final PMA+ vs SMT J Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 151SMT J Final PMA+ vs SMT G Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 152SMT I Final PMA+ vs SMT G Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 153SMT B Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 154SMT A Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 155SMT A Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT D Final PMA+ vs SMT E Final PMA+ vs SMT F Final PMA+ vs SMT G Final PMA+ vs SMT H Final PMA+ vs SMT I Final PMA+ vs SMT J Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 156SMT A Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT D Final PMA+ vs SMT E Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 157SMT F Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT G Final PMA+ vs SMT I Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 158SMT B Final PMA- vs SMT A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 159SMT C Final PMA- vs SMT A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 160SMT D Final PMA- vs SMT A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 161SMT E Final PMA- vs SMT A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 162SMT G Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 163SMT H Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 164SMT I Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 165SMT J Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 166SMT D Final PMA- vs SMT B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 167SMT E Final PMA- vs SMT B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 168SMT G Final PMA- vs SMT B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 169SMT I Final PMA- vs SMT B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 170SMT D Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 171SMT E Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 172SMT G Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 173SMT I Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 174SMT D Final PMA- vs SMT E Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 175SMT H Final PMA- vs SMT J Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 176SMT J Final PMA- vs SMT G Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 177SMT I Final PMA- vs SMT G Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 178SMT B Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 179SMT A Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 180SMT A Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT D Final PMA- vs SMT E Final PMA- vs SMT F Final PMA- vs SMT G Final PMA- vs SMT H Final PMA- vs SMT I Final PMA- vs SMT J Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 181SMT A Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT D Final PMA- vs SMT E Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 182SMT F Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT G Final PMA- vs SMT I Final PMA-PDFSVGPDFSVGPDFSVG
 
 

VIII. Analysis - Alpha Diversity

 

In ecology, alpha diversity (α-diversity) is the mean species diversity in sites or habitats at a local scale. The term was introduced by R. H. Whittaker[5][6] together with the terms beta diversity (β-diversity) and gamma diversity (γ-diversity). Whittaker's idea was that the total species diversity in a landscape (gamma diversity) is determined by two different things, the mean species diversity in sites or habitats at a more local scale (alpha diversity) and the differentiation among those habitats (beta diversity).

 

References:

  1. Whittaker, R. H. (1960) Vegetation of the Siskiyou Mountains, Oregon and California. Ecological Monographs, 30, 279–338. doi:10.2307/1943563
  2. Whittaker, R. H. (1972). Evolution and Measurement of Species Diversity. Taxon, 21, 213-251. doi:10.2307/1218190

 

Alpha Diversity Analysis by Rarefaction

Diversity measures are affected by the sampling depth. Rarefaction is a technique to assess species richness from the results of sampling. Rarefaction allows the calculation of species richness for a given number of individual samples, based on the construction of so-called rarefaction curves. This curve is a plot of the number of species as a function of the number of samples. Rarefaction curves generally grow rapidly at first, as the most common species are found, but the curves plateau as only the rarest species remain to be sampled [7].


References:

  1. Willis AD. Rarefaction, Alpha Diversity, and Statistics. Front Microbiol. 2019 Oct 23;10:2407. doi: 10.3389/fmicb.2019.02407. PMID: 31708888; PMCID: PMC6819366.

 
 
 

Boxplot of Alpha-diversity Indices

The two main factors taken into account when measuring diversity are richness and evenness. Richness is a measure of the number of different kinds of organisms present in a particular area. Evenness compares the similarity of the population size of each of the species present. There are many different ways to measure the richness and evenness. These measurements are called "estimators" or "indices". Below is a diversity of 3 commonly used indices showing the values for all the samples (dots) and in groups (boxes) at the species level.

Printed on each graph is the statistical significance p values of the difference between the groups. The significance is calculated using either Kruskal-Wallis test or the Wilcoxon rank sum test, both are non-parametric methods (since microbiome read count data are considered non-normally distributed) for testing whether samples originate from the same distribution (i.e., no difference between groups). The Kruskal-Wallis test is used to compare three or more independent groups to determine if there are statistically significant differences between their medians. The Wilcoxon Rank Sum test, also known as the Mann-Whitney U test, is used to compare two independent groups to determine if there is a significant difference between their distributions.
The p-value is shown on the top of each graph. A p-value < 0.05 is considered statistically significant between/among the test groups.

 
Alpha Diversity Box Plots for All Groups - Species Level
 
 
 
 
 
 
 
 
 
Alpha Diversity Box Plots for Individual Comparisons at Species level
 
Comparison 1SALIVA Pool 1 PMA+ vs SALIVA Pool 2 PMA+View in PDFView in SVG
Comparison 2SALIVA Pool 1 PMA- vs SALIVA Pool 2 PMA-View in PDFView in SVG
Comparison 3SALIVA Pool 1 PMA+ vs SALIVA Pool 1 PMA-View in PDFView in SVG
Comparison 4SALIVA Pool 2 PMA+ vs SALIVA Pool 2 PMA-View in PDFView in SVG
Comparison 5SST Saliva P1 PMA+ vs SST Baseline P1 PMA+View in PDFView in SVG
Comparison 6SST Saliva P2 PMA+ vs SST Baseline P2 PMA+View in PDFView in SVG
Comparison 7SST Saliva P1 PMA- vs SST Baseline P1 PMA-View in PDFView in SVG
Comparison 8SST Saliva P2 PMA- vs SST Baseline P2 PMA-View in PDFView in SVG
Comparison 9SST Saliva PMA+ vs SST Baseline PMA+View in PDFView in SVG
Comparison 10SST Saliva PMA- vs SST Baseline PMA-View in PDFView in SVG
Comparison 11SST Baseline PMA+ vs SST Baseline PMA-View in PDFView in SVG
Comparison 12SST Baseline P1 PMA+ vs SST Baseline P2 PMA+View in PDFView in SVG
Comparison 13SST Baseline P1 PMA- vs SST Baseline P2 PMA-View in PDFView in SVG
Comparison 14SST Baseline PMA+ vs SST Final A PMA+View in PDFView in SVG
Comparison 15SST Baseline PMA+ vs SST Final B PMA+View in PDFView in SVG
Comparison 16SST Baseline PMA+ vs SST Final C PMA+View in PDFView in SVG
Comparison 17SST Baseline PMA+ vs SST Final D PMA+View in PDFView in SVG
Comparison 18SST Baseline PMA+ vs SST Final E PMA+View in PDFView in SVG
Comparison 19SST Baseline PMA+ vs SST Final F PMA+View in PDFView in SVG
Comparison 20SST Baseline PMA+ vs SST Final G PMA+View in PDFView in SVG
Comparison 21SST Baseline PMA+ vs SST Final H PMA+View in PDFView in SVG
Comparison 22SST Baseline PMA+ vs SST Final I PMA+View in PDFView in SVG
Comparison 23SST Baseline PMA+ vs SST Final J PMA+View in PDFView in SVG
Comparison 24SST Final A PMA+ vs SST Final A PMA-View in PDFView in SVG
Comparison 25SST Final B PMA+ vs SST Final B PMA-View in PDFView in SVG
Comparison 26SST Final C PMA+ vs SST Final C PMA-View in PDFView in SVG
Comparison 27SST Final D PMA+ vs SST Final D PMA-View in PDFView in SVG
Comparison 28SST Final E PMA+ vs SST Final E PMA-View in PDFView in SVG
Comparison 29SST Final F PMA+ vs SST Final F PMA-View in PDFView in SVG
Comparison 30SST Final G PMA+ vs SST Final G PMA-View in PDFView in SVG
Comparison 31SST Final H PMA+ vs SST Final H PMA-View in PDFView in SVG
Comparison 32SST Final I PMA+ vs SST Final I PMA-View in PDFView in SVG
Comparison 33SST Final J PMA+ vs SST Final J PMA-View in PDFView in SVG
Comparison 34SST Baseline PMA- vs SST Final A PMA-View in PDFView in SVG
Comparison 35SST Baseline PMA- vs SST Final B PMA-View in PDFView in SVG
Comparison 36SST Baseline PMA- vs SST Final C PMA-View in PDFView in SVG
Comparison 37SST Baseline PMA- vs SST Final D PMA-View in PDFView in SVG
Comparison 38SST Baseline PMA- vs SST Final E PMA-View in PDFView in SVG
Comparison 39SST Baseline PMA- vs SST Final F PMA-View in PDFView in SVG
Comparison 40SST Baseline PMA- vs SST Final G PMA-View in PDFView in SVG
Comparison 41SST Baseline PMA- vs SST Final H PMA-View in PDFView in SVG
Comparison 42SST Baseline PMA- vs SST Final I PMA-View in PDFView in SVG
Comparison 43SST Baseline PMA- vs SST Final J PMA-View in PDFView in SVG
Comparison 44SST B Final PMA+ vs SST A Final PMA+View in PDFView in SVG
Comparison 45SST C Final PMA+ vs SST A Final PMA+View in PDFView in SVG
Comparison 46SST D Final PMA+ vs SST A Final PMA+View in PDFView in SVG
Comparison 47SST E Final PMA+ vs SST A Final PMA+View in PDFView in SVG
Comparison 48SST G Final PMA+ vs SST F Final PMA+View in PDFView in SVG
Comparison 49SST H Final PMA+ vs SST F Final PMA+View in PDFView in SVG
Comparison 50SST I Final PMA+ vs SST F Final PMA+View in PDFView in SVG
Comparison 51SST J Final PMA+ vs SST F Final PMA+View in PDFView in SVG
Comparison 52SST D Final PMA+ vs SST B Final PMA+View in PDFView in SVG
Comparison 53SST E Final PMA+ vs SST B Final PMA+View in PDFView in SVG
Comparison 54SST G Final PMA+ vs SST B Final PMA+View in PDFView in SVG
Comparison 55SST I Final PMA+ vs SST B Final PMA+View in PDFView in SVG
Comparison 56SST D Final PMA+ vs SST C Final PMA+View in PDFView in SVG
Comparison 57SST E Final PMA+ vs SST C Final PMA+View in PDFView in SVG
Comparison 58SST G Final PMA+ vs SST C Final PMA+View in PDFView in SVG
Comparison 59SST I Final PMA+ vs SST C Final PMA+View in PDFView in SVG
Comparison 60SST D Final PMA+ vs SST E Final PMA+View in PDFView in SVG
Comparison 61SST H Final PMA+ vs SST J Final PMA+View in PDFView in SVG
Comparison 62SST J Final PMA+ vs SST G Final PMA+View in PDFView in SVG
Comparison 63SST I Final PMA+ vs SST G Final PMA+View in PDFView in SVG
Comparison 64SST B Final PMA+ vs SST C Final PMA+View in PDFView in SVG
Comparison 65SST A Final PMA+ vs SST F Final PMA+View in PDFView in SVG
Comparison 66SST A Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST D Final PMA+ vs SST E Final PMA+ vs SST F Final PMA+ vs SST G Final PMA+ vs SST H Final PMA+ vs SST I Final PMA+ vs SST J Final PMA+View in PDFView in SVG
Comparison 67SST A Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST D Final PMA+ vs SST E Final PMA+View in PDFView in SVG
Comparison 68SST F Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST G Final PMA+ vs SST I Final PMA+View in PDFView in SVG
Comparison 69SST B Final PMA- vs SST A Final PMA-View in PDFView in SVG
Comparison 70SST C Final PMA- vs SST A Final PMA-View in PDFView in SVG
Comparison 71SST D Final PMA- vs SST A Final PMA-View in PDFView in SVG
Comparison 72SST E Final PMA- vs SST A Final PMA-View in PDFView in SVG
Comparison 73SST G Final PMA- vs SST F Final PMA-View in PDFView in SVG
Comparison 74SST H Final PMA- vs SST F Final PMA-View in PDFView in SVG
Comparison 75SST I Final PMA- vs SST F Final PMA-View in PDFView in SVG
Comparison 76SST J Final PMA- vs SST F Final PMA-View in PDFView in SVG
Comparison 77SST D Final PMA- vs SST B Final PMA-View in PDFView in SVG
Comparison 78SST E Final PMA- vs SST B Final PMA-View in PDFView in SVG
Comparison 79SST G Final PMA- vs SST B Final PMA-View in PDFView in SVG
Comparison 80SST I Final PMA- vs SST B Final PMA-View in PDFView in SVG
Comparison 81SST D Final PMA- vs SST C Final PMA-View in PDFView in SVG
Comparison 82SST E Final PMA- vs SST C Final PMA-View in PDFView in SVG
Comparison 83SST G Final PMA- vs SST C Final PMA-View in PDFView in SVG
Comparison 84SST I Final PMA- vs SST C Final PMA-View in PDFView in SVG
Comparison 85SST D Final PMA- vs SST E Final PMA-View in PDFView in SVG
Comparison 86SST H Final PMA- vs SST J Final PMA-View in PDFView in SVG
Comparison 87SST J Final PMA- vs SST G Final PMA-View in PDFView in SVG
Comparison 88SST I Final PMA- vs SST G Final PMA-View in PDFView in SVG
Comparison 89SST B Final PMA- vs SST C Final PMA-View in PDFView in SVG
Comparison 90SST A Final PMA- vs SST F Final PMA-View in PDFView in SVG
Comparison 91SST A Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST D Final PMA- vs SST E Final PMA- vs SST F Final PMA- vs SST G Final PMA- vs SST H Final PMA- vs SST I Final PMA- vs SST J Final PMA-View in PDFView in SVG
Comparison 92SST A Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST D Final PMA- vs SST E Final PMA-View in PDFView in SVG
Comparison 93SST F Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST G Final PMA- vs SST I Final PMA-View in PDFView in SVG
Comparison 94SMT Saliva P1 PMA+ vs SMT Baseline P1 PMA+View in PDFView in SVG
Comparison 95SMT Saliva P2 PMA+ vs SMT Baseline P2 PMA+View in PDFView in SVG
Comparison 96SMT Saliva P1 PMA- vs SMT Baseline P1 PMA-View in PDFView in SVG
Comparison 97SMT Saliva P2 PMA- vs SMT Baseline P2 PMA-View in PDFView in SVG
Comparison 98SMT Saliva PMA+ vs SMT Baseline PMA+View in PDFView in SVG
Comparison 99SMT Saliva PMA- vs SMT Baseline PMA-View in PDFView in SVG
Comparison 100SMT Baseline PMA+ vs SMT Baseline PMA-View in PDFView in SVG
Comparison 101SMT Baseline P1 PMA+ vs SMT Baseline P2 PMA+View in PDFView in SVG
Comparison 102SMT Baseline P1 PMA- vs SMT Baseline P2 PMA-View in PDFView in SVG
Comparison 103SMT Baseline PMA+ vs SMT Final A PMA+View in PDFView in SVG
Comparison 104SMT Baseline PMA+ vs SMT Final B PMA+View in PDFView in SVG
Comparison 105SMT Baseline PMA+ vs SMT Final C PMA+View in PDFView in SVG
Comparison 106SMT Baseline PMA+ vs SMT Final D PMA+View in PDFView in SVG
Comparison 107SMT Baseline PMA+ vs SMT Final E PMA+View in PDFView in SVG
Comparison 108SMT Baseline PMA+ vs SMT Final F PMA+View in PDFView in SVG
Comparison 109SMT Baseline PMA+ vs SMT Final G PMA+View in PDFView in SVG
Comparison 110SMT Baseline PMA+ vs SMT Final H PMA+View in PDFView in SVG
Comparison 111SMT Baseline PMA+ vs SMT Final I PMA+View in PDFView in SVG
Comparison 112SMT Baseline PMA+ vs SMT Final J PMA+View in PDFView in SVG
Comparison 113SMT Final A PMA+ vs SMT Final A PMA-View in PDFView in SVG
Comparison 114SMT Final B PMA+ vs SMT Final B PMA-View in PDFView in SVG
Comparison 115SMT Final C PMA+ vs SMT Final C PMA-View in PDFView in SVG
Comparison 116SMT Final D PMA+ vs SMT Final D PMA-View in PDFView in SVG
Comparison 117SMT Final E PMA+ vs SMT Final E PMA-View in PDFView in SVG
Comparison 118SMT Final F PMA+ vs SMT Final F PMA-View in PDFView in SVG
Comparison 119SMT Final G PMA+ vs SMT Final G PMA-View in PDFView in SVG
Comparison 120SMT Final H PMA+ vs SMT Final H PMA-View in PDFView in SVG
Comparison 121SMT Final I PMA+ vs SMT Final I PMA-View in PDFView in SVG
Comparison 122SMT Final J PMA+ vs SMT Final J PMA-View in PDFView in SVG
Comparison 123SMT Baseline PMA- vs SMT Final A PMA-View in PDFView in SVG
Comparison 124SMT Baseline PMA- vs SMT Final B PMA-View in PDFView in SVG
Comparison 125SMT Baseline PMA- vs SMT Final C PMA-View in PDFView in SVG
Comparison 126SMT Baseline PMA- vs SMT Final D PMA-View in PDFView in SVG
Comparison 127SMT Baseline PMA- vs SMT Final E PMA-View in PDFView in SVG
Comparison 128SMT Baseline PMA- vs SMT Final F PMA-View in PDFView in SVG
Comparison 129SMT Baseline PMA- vs SMT Final G PMA-View in PDFView in SVG
Comparison 130SMT Baseline PMA- vs SMT Final H PMA-View in PDFView in SVG
Comparison 131SMT Baseline PMA- vs SMT Final I PMA-View in PDFView in SVG
Comparison 132SMT Baseline PMA- vs SMT Final J PMA-View in PDFView in SVG
Comparison 133SMT B Final PMA+ vs SMT A Final PMA+View in PDFView in SVG
Comparison 134SMT C Final PMA+ vs SMT A Final PMA+View in PDFView in SVG
Comparison 135SMT D Final PMA+ vs SMT A Final PMA+View in PDFView in SVG
Comparison 136SMT E Final PMA+ vs SMT A Final PMA+View in PDFView in SVG
Comparison 137SMT G Final PMA+ vs SMT F Final PMA+View in PDFView in SVG
Comparison 138SMT H Final PMA+ vs SMT F Final PMA+View in PDFView in SVG
Comparison 139SMT I Final PMA+ vs SMT F Final PMA+View in PDFView in SVG
Comparison 140SMT J Final PMA+ vs SMT F Final PMA+View in PDFView in SVG
Comparison 141SMT D Final PMA+ vs SMT B Final PMA+View in PDFView in SVG
Comparison 142SMT E Final PMA+ vs SMT B Final PMA+View in PDFView in SVG
Comparison 143SMT G Final PMA+ vs SMT B Final PMA+View in PDFView in SVG
Comparison 144SMT I Final PMA+ vs SMT B Final PMA+View in PDFView in SVG
Comparison 145SMT D Final PMA+ vs SMT C Final PMA+View in PDFView in SVG
Comparison 146SMT E Final PMA+ vs SMT C Final PMA+View in PDFView in SVG
Comparison 147SMT G Final PMA+ vs SMT C Final PMA+View in PDFView in SVG
Comparison 148SMT I Final PMA+ vs SMT C Final PMA+View in PDFView in SVG
Comparison 149SMT D Final PMA+ vs SMT E Final PMA+View in PDFView in SVG
Comparison 150SMT H Final PMA+ vs SMT J Final PMA+View in PDFView in SVG
Comparison 151SMT J Final PMA+ vs SMT G Final PMA+View in PDFView in SVG
Comparison 152SMT I Final PMA+ vs SMT G Final PMA+View in PDFView in SVG
Comparison 153SMT B Final PMA+ vs SMT C Final PMA+View in PDFView in SVG
Comparison 154SMT A Final PMA+ vs SMT F Final PMA+View in PDFView in SVG
Comparison 155SMT A Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT D Final PMA+ vs SMT E Final PMA+ vs SMT F Final PMA+ vs SMT G Final PMA+ vs SMT H Final PMA+ vs SMT I Final PMA+ vs SMT J Final PMA+View in PDFView in SVG
Comparison 156SMT A Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT D Final PMA+ vs SMT E Final PMA+View in PDFView in SVG
Comparison 157SMT F Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT G Final PMA+ vs SMT I Final PMA+View in PDFView in SVG
Comparison 158SMT B Final PMA- vs SMT A Final PMA-View in PDFView in SVG
Comparison 159SMT C Final PMA- vs SMT A Final PMA-View in PDFView in SVG
Comparison 160SMT D Final PMA- vs SMT A Final PMA-View in PDFView in SVG
Comparison 161SMT E Final PMA- vs SMT A Final PMA-View in PDFView in SVG
Comparison 162SMT G Final PMA- vs SMT F Final PMA-View in PDFView in SVG
Comparison 163SMT H Final PMA- vs SMT F Final PMA-View in PDFView in SVG
Comparison 164SMT I Final PMA- vs SMT F Final PMA-View in PDFView in SVG
Comparison 165SMT J Final PMA- vs SMT F Final PMA-View in PDFView in SVG
Comparison 166SMT D Final PMA- vs SMT B Final PMA-View in PDFView in SVG
Comparison 167SMT E Final PMA- vs SMT B Final PMA-View in PDFView in SVG
Comparison 168SMT G Final PMA- vs SMT B Final PMA-View in PDFView in SVG
Comparison 169SMT I Final PMA- vs SMT B Final PMA-View in PDFView in SVG
Comparison 170SMT D Final PMA- vs SMT C Final PMA-View in PDFView in SVG
Comparison 171SMT E Final PMA- vs SMT C Final PMA-View in PDFView in SVG
Comparison 172SMT G Final PMA- vs SMT C Final PMA-View in PDFView in SVG
Comparison 173SMT I Final PMA- vs SMT C Final PMA-View in PDFView in SVG
Comparison 174SMT D Final PMA- vs SMT E Final PMA-View in PDFView in SVG
Comparison 175SMT H Final PMA- vs SMT J Final PMA-View in PDFView in SVG
Comparison 176SMT J Final PMA- vs SMT G Final PMA-View in PDFView in SVG
Comparison 177SMT I Final PMA- vs SMT G Final PMA-View in PDFView in SVG
Comparison 178SMT B Final PMA- vs SMT C Final PMA-View in PDFView in SVG
Comparison 179SMT A Final PMA- vs SMT F Final PMA-View in PDFView in SVG
Comparison 180SMT A Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT D Final PMA- vs SMT E Final PMA- vs SMT F Final PMA- vs SMT G Final PMA- vs SMT H Final PMA- vs SMT I Final PMA- vs SMT J Final PMA-View in PDFView in SVG
Comparison 181SMT A Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT D Final PMA- vs SMT E Final PMA-View in PDFView in SVG
Comparison 182SMT F Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT G Final PMA- vs SMT I Final PMA-View in PDFView in SVG
 
The above comparisons are at the species-level. Comparisons of other taxonomy levels, from phylum to genus, are also available:
 
 
 

IX. Analysis - Beta Diversity

 

NMDS and PCoA Plots

Beta diversity compares the similarity (or dissimilarity) of microbial profiles between different groups of samples. There are many different similarity/dissimilarity metrics [8]. In general, they can be quantitative (using sequence abundance, e.g., Bray-Curtis or weighted UniFrac) or binary (considering only presence-absence of sequences, e.g., binary Jaccard or unweighted UniFrac). They can be even based on phylogeny (e.g., UniFrac metrics) or not (non-UniFrac metrics, such as Bray-Curtis, etc.).

For microbiome studies, species profiles of samples can be compared with the Bray-Curtis dissimilarity, which is based on the count data type. The pair-wise Bray-Curtis dissimilarity matrix of all samples can then be subject to either multi-dimensional scaling (MDS, also known as PCoA) or non-metric MDS (NMDS).

MDS/PCoA is a scaling or ordination method that starts with a matrix of similarities or dissimilarities between a set of samples and aims to produce a low-dimensional graphical plot of the data in such a way that distances between points in the plot are close to original dissimilarities.

NMDS is similar to MDS, however it does not use the dissimilarities data, instead it converts them into the ranks and use these ranks in the calculation.

References:

  1. Plantinga, AM, Wu, MC (2021). Beta Diversity and Distance-Based Analysis of Microbiome Data. In: Datta, S., Guha, S. (eds) Statistical Analysis of Microbiome Data. Frontiers in Probability and the Statistical Sciences. Springer, Cham. https://doi.org/10.1007/978-3-030-73351-3_5

In our beta diversity analysis, Bray-Curtis dissimilarity matrix was first calculated and then plotted by the PCoA and NMDS separately. Below are beta diveristy results for all groups together, at the Species level:

 
 
NMDS and PCoA Plots for All Groups - Species Level
 
 
 
 
 

The above PCoA and NMDS plots are based on count data. The count data can also be transformed into centered log ratio (CLR) for each species. The CLR data is no longer count data and cannot be used in Bray-Curtis dissimilarity calculation. Instead CLR can be compared with Euclidean distances. When CLR data are compared by Euclidean distance, the distance is also called Aitchison distance.

Below are the NMDS and PCoA plots of the Aitchison distances of the samples at the Species level:

 
 
 
 
 
 
 
NMDS and PCoA Plots for Individual Comparisons at Species level
 
 
Comparison No.Comparison NameNMDAPCoA
Bray-CurtisCLR EuclideanBray-CurtisCLR Euclidean
Comparison 1SALIVA Pool 1 PMA+ vs SALIVA Pool 2 PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 2SALIVA Pool 1 PMA- vs SALIVA Pool 2 PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 3SALIVA Pool 1 PMA+ vs SALIVA Pool 1 PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 4SALIVA Pool 2 PMA+ vs SALIVA Pool 2 PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 5SST Saliva P1 PMA+ vs SST Baseline P1 PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 6SST Saliva P2 PMA+ vs SST Baseline P2 PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 7SST Saliva P1 PMA- vs SST Baseline P1 PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 8SST Saliva P2 PMA- vs SST Baseline P2 PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 9SST Saliva PMA+ vs SST Baseline PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 10SST Saliva PMA- vs SST Baseline PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 11SST Baseline PMA+ vs SST Baseline PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 12SST Baseline P1 PMA+ vs SST Baseline P2 PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 13SST Baseline P1 PMA- vs SST Baseline P2 PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 14SST Baseline PMA+ vs SST Final A PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 15SST Baseline PMA+ vs SST Final B PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 16SST Baseline PMA+ vs SST Final C PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 17SST Baseline PMA+ vs SST Final D PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 18SST Baseline PMA+ vs SST Final E PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 19SST Baseline PMA+ vs SST Final F PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 20SST Baseline PMA+ vs SST Final G PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 21SST Baseline PMA+ vs SST Final H PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 22SST Baseline PMA+ vs SST Final I PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 23SST Baseline PMA+ vs SST Final J PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 24SST Final A PMA+ vs SST Final A PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 25SST Final B PMA+ vs SST Final B PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 26SST Final C PMA+ vs SST Final C PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 27SST Final D PMA+ vs SST Final D PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 28SST Final E PMA+ vs SST Final E PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 29SST Final F PMA+ vs SST Final F PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 30SST Final G PMA+ vs SST Final G PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 31SST Final H PMA+ vs SST Final H PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 32SST Final I PMA+ vs SST Final I PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 33SST Final J PMA+ vs SST Final J PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 34SST Baseline PMA- vs SST Final A PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 35SST Baseline PMA- vs SST Final B PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 36SST Baseline PMA- vs SST Final C PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 37SST Baseline PMA- vs SST Final D PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 38SST Baseline PMA- vs SST Final E PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 39SST Baseline PMA- vs SST Final F PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 40SST Baseline PMA- vs SST Final G PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 41SST Baseline PMA- vs SST Final H PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 42SST Baseline PMA- vs SST Final I PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 43SST Baseline PMA- vs SST Final J PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 44SST B Final PMA+ vs SST A Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 45SST C Final PMA+ vs SST A Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 46SST D Final PMA+ vs SST A Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 47SST E Final PMA+ vs SST A Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 48SST G Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 49SST H Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 50SST I Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 51SST J Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 52SST D Final PMA+ vs SST B Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 53SST E Final PMA+ vs SST B Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 54SST G Final PMA+ vs SST B Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 55SST I Final PMA+ vs SST B Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 56SST D Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 57SST E Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 58SST G Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 59SST I Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 60SST D Final PMA+ vs SST E Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 61SST H Final PMA+ vs SST J Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 62SST J Final PMA+ vs SST G Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 63SST I Final PMA+ vs SST G Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 64SST B Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 65SST A Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 66SST A Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST D Final PMA+ vs SST E Final PMA+ vs SST F Final PMA+ vs SST G Final PMA+ vs SST H Final PMA+ vs SST I Final PMA+ vs SST J Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 67SST A Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST D Final PMA+ vs SST E Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 68SST F Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST G Final PMA+ vs SST I Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 69SST B Final PMA- vs SST A Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 70SST C Final PMA- vs SST A Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 71SST D Final PMA- vs SST A Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 72SST E Final PMA- vs SST A Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 73SST G Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 74SST H Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 75SST I Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 76SST J Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 77SST D Final PMA- vs SST B Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 78SST E Final PMA- vs SST B Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 79SST G Final PMA- vs SST B Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 80SST I Final PMA- vs SST B Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 81SST D Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 82SST E Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 83SST G Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 84SST I Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 85SST D Final PMA- vs SST E Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 86SST H Final PMA- vs SST J Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 87SST J Final PMA- vs SST G Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 88SST I Final PMA- vs SST G Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 89SST B Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 90SST A Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 91SST A Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST D Final PMA- vs SST E Final PMA- vs SST F Final PMA- vs SST G Final PMA- vs SST H Final PMA- vs SST I Final PMA- vs SST J Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 92SST A Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST D Final PMA- vs SST E Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 93SST F Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST G Final PMA- vs SST I Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 94SMT Saliva P1 PMA+ vs SMT Baseline P1 PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 95SMT Saliva P2 PMA+ vs SMT Baseline P2 PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 96SMT Saliva P1 PMA- vs SMT Baseline P1 PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 97SMT Saliva P2 PMA- vs SMT Baseline P2 PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 98SMT Saliva PMA+ vs SMT Baseline PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 99SMT Saliva PMA- vs SMT Baseline PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 100SMT Baseline PMA+ vs SMT Baseline PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 101SMT Baseline P1 PMA+ vs SMT Baseline P2 PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 102SMT Baseline P1 PMA- vs SMT Baseline P2 PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 103SMT Baseline PMA+ vs SMT Final A PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 104SMT Baseline PMA+ vs SMT Final B PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 105SMT Baseline PMA+ vs SMT Final C PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 106SMT Baseline PMA+ vs SMT Final D PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 107SMT Baseline PMA+ vs SMT Final E PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 108SMT Baseline PMA+ vs SMT Final F PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 109SMT Baseline PMA+ vs SMT Final G PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 110SMT Baseline PMA+ vs SMT Final H PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 111SMT Baseline PMA+ vs SMT Final I PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 112SMT Baseline PMA+ vs SMT Final J PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 113SMT Final A PMA+ vs SMT Final A PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 114SMT Final B PMA+ vs SMT Final B PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 115SMT Final C PMA+ vs SMT Final C PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 116SMT Final D PMA+ vs SMT Final D PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 117SMT Final E PMA+ vs SMT Final E PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 118SMT Final F PMA+ vs SMT Final F PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 119SMT Final G PMA+ vs SMT Final G PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 120SMT Final H PMA+ vs SMT Final H PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 121SMT Final I PMA+ vs SMT Final I PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 122SMT Final J PMA+ vs SMT Final J PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 123SMT Baseline PMA- vs SMT Final A PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 124SMT Baseline PMA- vs SMT Final B PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 125SMT Baseline PMA- vs SMT Final C PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 126SMT Baseline PMA- vs SMT Final D PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 127SMT Baseline PMA- vs SMT Final E PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 128SMT Baseline PMA- vs SMT Final F PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 129SMT Baseline PMA- vs SMT Final G PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 130SMT Baseline PMA- vs SMT Final H PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 131SMT Baseline PMA- vs SMT Final I PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 132SMT Baseline PMA- vs SMT Final J PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 133SMT B Final PMA+ vs SMT A Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 134SMT C Final PMA+ vs SMT A Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 135SMT D Final PMA+ vs SMT A Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 136SMT E Final PMA+ vs SMT A Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 137SMT G Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 138SMT H Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 139SMT I Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 140SMT J Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 141SMT D Final PMA+ vs SMT B Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 142SMT E Final PMA+ vs SMT B Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 143SMT G Final PMA+ vs SMT B Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 144SMT I Final PMA+ vs SMT B Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 145SMT D Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 146SMT E Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 147SMT G Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 148SMT I Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 149SMT D Final PMA+ vs SMT E Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 150SMT H Final PMA+ vs SMT J Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 151SMT J Final PMA+ vs SMT G Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 152SMT I Final PMA+ vs SMT G Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 153SMT B Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 154SMT A Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 155SMT A Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT D Final PMA+ vs SMT E Final PMA+ vs SMT F Final PMA+ vs SMT G Final PMA+ vs SMT H Final PMA+ vs SMT I Final PMA+ vs SMT J Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 156SMT A Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT D Final PMA+ vs SMT E Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 157SMT F Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT G Final PMA+ vs SMT I Final PMA+PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 158SMT B Final PMA- vs SMT A Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 159SMT C Final PMA- vs SMT A Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 160SMT D Final PMA- vs SMT A Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 161SMT E Final PMA- vs SMT A Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 162SMT G Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 163SMT H Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 164SMT I Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 165SMT J Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 166SMT D Final PMA- vs SMT B Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 167SMT E Final PMA- vs SMT B Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 168SMT G Final PMA- vs SMT B Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 169SMT I Final PMA- vs SMT B Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 170SMT D Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 171SMT E Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 172SMT G Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 173SMT I Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 174SMT D Final PMA- vs SMT E Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 175SMT H Final PMA- vs SMT J Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 176SMT J Final PMA- vs SMT G Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 177SMT I Final PMA- vs SMT G Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 178SMT B Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 179SMT A Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 180SMT A Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT D Final PMA- vs SMT E Final PMA- vs SMT F Final PMA- vs SMT G Final PMA- vs SMT H Final PMA- vs SMT I Final PMA- vs SMT J Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 181SMT A Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT D Final PMA- vs SMT E Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
Comparison 182SMT F Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT G Final PMA- vs SMT I Final PMA-PDFSVGPDFSVGPDFSVGPDFSVG
 
 
 
 
 
 

Interactive 3D PCoA Plots - Bray-Curtis Dissimilarity

 
 
 

Interactive 3D PCoA Plots - Euclidean Distance

 
 
 

Interactive 3D PCoA Plots - Correlation Coefficients

 
 
 

X. Analysis - Differential Abundance

16S rRNA next generation sequencing (NGS) generates a fixed number of reads that reflect the proportion of different species in a sample, i.e., the relative abundance of species, instead of the absolute abundance. In Mathematics, measurements involving probabilities, proportions, percentages, and ppm can all be thought of as compositional data. This makes the microbiome read count data “compositional” (Gloor et al, 2017). In general, compositional data represent parts of a whole which only carry relative information [9].

The problem of microbiome data being compositional arises when comparing two groups of samples for identifying “differentially abundant” species. A species with the same absolute abundance between two conditions, its relative abundances in the two conditions (e.g., percent abundance) can become different if the relative abundance of other species change greatly. This problem can lead to incorrect conclusion in terms of differential abundance for microbial species in the samples.

When studying differential abundance (DA), the current better approach is to transform the read count data into log ratio data. The ratios are calculated between read counts of all species in a sample to a “reference” count (e.g., mean read count of the sample). The log ratio data allow the detection of DA species without being affected by percentage bias mentioned above

In this report, a compositional DA analysis tool “ANCOM” (analysis of composition of microbiomes) was used [10]. ANCOM transforms the count data into log-ratios and thus is more suitable for comparing the composition of microbiomes in two or more populations. "ANCOM" generates a table of features with W-statistics and whether the null hypothesis is rejected. The “W” is the W-statistic, or number of features that a single feature is tested to be significantly different against. Hence the higher the "W" the more statistical sifgnificant that a feature/species is differentially abundant.

 
 
 
 

ANCOM-BC2 Differential Abundance Analysis

 

Starting with version V1.2, we include the results of ANCOM-BC (Analysis of Compositions of Microbiomes with Bias Correction) (Lin and Peddada 2020) [11]. ANCOM-BC is an updated version of "ANCOM" that:
(a) provides statistically valid test with appropriate p-values,
(b) provides confidence intervals for differential abundance of each taxon,
(c) controls the False Discovery Rate (FDR),
(d) maintains adequate power, and
(e) is computationally simple to implement.

The bias correction (BC) addresses a challenging problem of the bias introduced by differences in the sampling fractions across samples. This bias has been a major hurdle in performing DA analysis of microbiome data. ANCOM-BC estimates the unknown sampling fractions and corrects the bias induced by their differences among samples. The absolute abundance data are modeled using a linear regression framework.

Starting with version V1.43, ANCOM-BC2 is used instead of ANCOM-BC, So that multiple pairwise directional test can be performed (if there are more than two gorups in a comparison). When performing pairwise directional test, the mixed directional false discover rate (mdFDR) is taken into account. The mdFDR is the combination of false discovery rate due to multiple testing, multiple pairwise comparisons, and directional tests within each pairwise comparison. The mdFDR is adopted from (Guo, Sarkar, and Peddada 2010 [12]; Grandhi, Guo, and Peddada 2016 [13]). For more detail explanation and additional features of ANCOM-BC2 please see author's documentation.

References:

  1. Gloor GB, Macklaim JM, Pawlowsky-Glahn V, Egozcue JJ. Microbiome Datasets Are Compositional: And This Is Not Optional. Front Microbiol. 2017 Nov 15;8:2224. doi: 10.3389/fmicb.2017.02224. PMID: 29187837; PMCID: PMC5695134.
  2. Mandal S, Van Treuren W, White RA, Eggesbø M, Knight R, Peddada SD. Analysis of composition of microbiomes: a novel method for studying microbial composition. Microb Ecol Health Dis. 2015 May 29;26:27663. doi: 10.3402/mehd.v26.27663. PMID: 26028277; PMCID: PMC4450248.
  1. Lin H, Peddada SD. Analysis of compositions of microbiomes with bias correction. Nat Commun. 2020 Jul 14;11(1):3514. doi: 10.1038/s41467-020-17041-7. PMID: 32665548; PMCID: PMC7360769.
  2. Guo W, Sarkar SK, Peddada SD. Controlling false discoveries in multidimensional directional decisions, with applications to gene expression data on ordered categories. Biometrics. 2010 Jun;66(2):485-92. doi: 10.1111/j.1541-0420.2009.01292.x. Epub 2009 Jul 23. PMID: 19645703; PMCID: PMC2895927.
  3. Grandhi A, Guo W, Peddada SD. A multiple testing procedure for multi-dimensional pairwise comparisons with application to gene expression studies. BMC Bioinformatics. 2016 Feb 25;17:104. doi: 10.1186/s12859-016-0937-5. PMID: 26917217; PMCID: PMC4768411.
 
 
ANCOM-BC Results for Individual Comparisons
 
Comparison No.Comparison Name
Comparison 1.SALIVA Pool 1 PMA+ vs SALIVA Pool 2 PMA+
Comparison 2.SALIVA Pool 1 PMA- vs SALIVA Pool 2 PMA-
Comparison 3.SALIVA Pool 1 PMA+ vs SALIVA Pool 1 PMA-
Comparison 4.SALIVA Pool 2 PMA+ vs SALIVA Pool 2 PMA-
Comparison 5.SST Saliva P1 PMA+ vs SST Baseline P1 PMA+
Comparison 6.SST Saliva P2 PMA+ vs SST Baseline P2 PMA+
Comparison 7.SST Saliva P1 PMA- vs SST Baseline P1 PMA-
Comparison 8.SST Saliva P2 PMA- vs SST Baseline P2 PMA-
Comparison 9.SST Saliva PMA+ vs SST Baseline PMA+
Comparison 10.SST Saliva PMA- vs SST Baseline PMA-
Comparison 11.SST Baseline PMA+ vs SST Baseline PMA-
Comparison 12.SST Baseline P1 PMA+ vs SST Baseline P2 PMA+
Comparison 13.SST Baseline P1 PMA- vs SST Baseline P2 PMA-
Comparison 14.SST Baseline PMA+ vs SST Final A PMA+
Comparison 15.SST Baseline PMA+ vs SST Final B PMA+
Comparison 16.SST Baseline PMA+ vs SST Final C PMA+
Comparison 17.SST Baseline PMA+ vs SST Final D PMA+
Comparison 18.SST Baseline PMA+ vs SST Final E PMA+
Comparison 19.SST Baseline PMA+ vs SST Final F PMA+
Comparison 20.SST Baseline PMA+ vs SST Final G PMA+
Comparison 21.SST Baseline PMA+ vs SST Final H PMA+
Comparison 22.SST Baseline PMA+ vs SST Final I PMA+
Comparison 23.SST Baseline PMA+ vs SST Final J PMA+
Comparison 24.SST Final A PMA+ vs SST Final A PMA-
Comparison 25.SST Final B PMA+ vs SST Final B PMA-
Comparison 26.SST Final C PMA+ vs SST Final C PMA-
Comparison 27.SST Final D PMA+ vs SST Final D PMA-
Comparison 28.SST Final E PMA+ vs SST Final E PMA-
Comparison 29.SST Final F PMA+ vs SST Final F PMA-
Comparison 30.SST Final G PMA+ vs SST Final G PMA-
Comparison 31.SST Final H PMA+ vs SST Final H PMA-
Comparison 32.SST Final I PMA+ vs SST Final I PMA-
Comparison 33.SST Final J PMA+ vs SST Final J PMA-
Comparison 34.SST Baseline PMA- vs SST Final A PMA-
Comparison 35.SST Baseline PMA- vs SST Final B PMA-
Comparison 36.SST Baseline PMA- vs SST Final C PMA-
Comparison 37.SST Baseline PMA- vs SST Final D PMA-
Comparison 38.SST Baseline PMA- vs SST Final E PMA-
Comparison 39.SST Baseline PMA- vs SST Final F PMA-
Comparison 40.SST Baseline PMA- vs SST Final G PMA-
Comparison 41.SST Baseline PMA- vs SST Final H PMA-
Comparison 42.SST Baseline PMA- vs SST Final I PMA-
Comparison 43.SST Baseline PMA- vs SST Final J PMA-
Comparison 44.SST B Final PMA+ vs SST A Final PMA+
Comparison 45.SST C Final PMA+ vs SST A Final PMA+
Comparison 46.SST D Final PMA+ vs SST A Final PMA+
Comparison 47.SST E Final PMA+ vs SST A Final PMA+
Comparison 48.SST G Final PMA+ vs SST F Final PMA+
Comparison 49.SST H Final PMA+ vs SST F Final PMA+
Comparison 50.SST I Final PMA+ vs SST F Final PMA+
Comparison 51.SST J Final PMA+ vs SST F Final PMA+
Comparison 52.SST D Final PMA+ vs SST B Final PMA+
Comparison 53.SST E Final PMA+ vs SST B Final PMA+
Comparison 54.SST G Final PMA+ vs SST B Final PMA+
Comparison 55.SST I Final PMA+ vs SST B Final PMA+
Comparison 56.SST D Final PMA+ vs SST C Final PMA+
Comparison 57.SST E Final PMA+ vs SST C Final PMA+
Comparison 58.SST G Final PMA+ vs SST C Final PMA+
Comparison 59.SST I Final PMA+ vs SST C Final PMA+
Comparison 60.SST D Final PMA+ vs SST E Final PMA+
Comparison 61.SST H Final PMA+ vs SST J Final PMA+
Comparison 62.SST J Final PMA+ vs SST G Final PMA+
Comparison 63.SST I Final PMA+ vs SST G Final PMA+
Comparison 64.SST B Final PMA+ vs SST C Final PMA+
Comparison 65.SST A Final PMA+ vs SST F Final PMA+
Comparison 66.SST A Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST D Final PMA+ vs SST E Final PMA+ vs SST F Final PMA+ vs SST G Final PMA+ vs SST H Final PMA+ vs SST I Final PMA+ vs SST J Final PMA+
Comparison 67.SST A Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST D Final PMA+ vs SST E Final PMA+
Comparison 68.SST F Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST G Final PMA+ vs SST I Final PMA+
Comparison 69.SST B Final PMA- vs SST A Final PMA-
Comparison 70.SST C Final PMA- vs SST A Final PMA-
Comparison 71.SST D Final PMA- vs SST A Final PMA-
Comparison 72.SST E Final PMA- vs SST A Final PMA-
Comparison 73.SST G Final PMA- vs SST F Final PMA-
Comparison 74.SST H Final PMA- vs SST F Final PMA-
Comparison 75.SST I Final PMA- vs SST F Final PMA-
Comparison 76.SST J Final PMA- vs SST F Final PMA-
Comparison 77.SST D Final PMA- vs SST B Final PMA-
Comparison 78.SST E Final PMA- vs SST B Final PMA-
Comparison 79.SST G Final PMA- vs SST B Final PMA-
Comparison 80.SST I Final PMA- vs SST B Final PMA-
Comparison 81.SST D Final PMA- vs SST C Final PMA-
Comparison 82.SST E Final PMA- vs SST C Final PMA-
Comparison 83.SST G Final PMA- vs SST C Final PMA-
Comparison 84.SST I Final PMA- vs SST C Final PMA-
Comparison 85.SST D Final PMA- vs SST E Final PMA-
Comparison 86.SST H Final PMA- vs SST J Final PMA-
Comparison 87.SST J Final PMA- vs SST G Final PMA-
Comparison 88.SST I Final PMA- vs SST G Final PMA-
Comparison 89.SST B Final PMA- vs SST C Final PMA-
Comparison 90.SST A Final PMA- vs SST F Final PMA-
Comparison 91.SST A Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST D Final PMA- vs SST E Final PMA- vs SST F Final PMA- vs SST G Final PMA- vs SST H Final PMA- vs SST I Final PMA- vs SST J Final PMA-
Comparison 92.SST A Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST D Final PMA- vs SST E Final PMA-
Comparison 93.SST F Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST G Final PMA- vs SST I Final PMA-
Comparison 94.SMT Saliva P1 PMA+ vs SMT Baseline P1 PMA+
Comparison 95.SMT Saliva P2 PMA+ vs SMT Baseline P2 PMA+
Comparison 96.SMT Saliva P1 PMA- vs SMT Baseline P1 PMA-
Comparison 97.SMT Saliva P2 PMA- vs SMT Baseline P2 PMA-
Comparison 98.SMT Saliva PMA+ vs SMT Baseline PMA+
Comparison 99.SMT Saliva PMA- vs SMT Baseline PMA-
Comparison 100.SMT Baseline PMA+ vs SMT Baseline PMA-
Comparison 101.SMT Baseline P1 PMA+ vs SMT Baseline P2 PMA+
Comparison 102.SMT Baseline P1 PMA- vs SMT Baseline P2 PMA-
Comparison 103.SMT Baseline PMA+ vs SMT Final A PMA+
Comparison 104.SMT Baseline PMA+ vs SMT Final B PMA+
Comparison 105.SMT Baseline PMA+ vs SMT Final C PMA+
Comparison 106.SMT Baseline PMA+ vs SMT Final D PMA+
Comparison 107.SMT Baseline PMA+ vs SMT Final E PMA+
Comparison 108.SMT Baseline PMA+ vs SMT Final F PMA+
Comparison 109.SMT Baseline PMA+ vs SMT Final G PMA+
Comparison 110.SMT Baseline PMA+ vs SMT Final H PMA+
Comparison 111.SMT Baseline PMA+ vs SMT Final I PMA+
Comparison 112.SMT Baseline PMA+ vs SMT Final J PMA+
Comparison 113.SMT Final A PMA+ vs SMT Final A PMA-
Comparison 114.SMT Final B PMA+ vs SMT Final B PMA-
Comparison 115.SMT Final C PMA+ vs SMT Final C PMA-
Comparison 116.SMT Final D PMA+ vs SMT Final D PMA-
Comparison 117.SMT Final E PMA+ vs SMT Final E PMA-
Comparison 118.SMT Final F PMA+ vs SMT Final F PMA-
Comparison 119.SMT Final G PMA+ vs SMT Final G PMA-
Comparison 120.SMT Final H PMA+ vs SMT Final H PMA-
Comparison 121.SMT Final I PMA+ vs SMT Final I PMA-
Comparison 122.SMT Final J PMA+ vs SMT Final J PMA-
Comparison 123.SMT Baseline PMA- vs SMT Final A PMA-
Comparison 124.SMT Baseline PMA- vs SMT Final B PMA-
Comparison 125.SMT Baseline PMA- vs SMT Final C PMA-
Comparison 126.SMT Baseline PMA- vs SMT Final D PMA-
Comparison 127.SMT Baseline PMA- vs SMT Final E PMA-
Comparison 128.SMT Baseline PMA- vs SMT Final F PMA-
Comparison 129.SMT Baseline PMA- vs SMT Final G PMA-
Comparison 130.SMT Baseline PMA- vs SMT Final H PMA-
Comparison 131.SMT Baseline PMA- vs SMT Final I PMA-
Comparison 132.SMT Baseline PMA- vs SMT Final J PMA-
Comparison 133.SMT B Final PMA+ vs SMT A Final PMA+
Comparison 134.SMT C Final PMA+ vs SMT A Final PMA+
Comparison 135.SMT D Final PMA+ vs SMT A Final PMA+
Comparison 136.SMT E Final PMA+ vs SMT A Final PMA+
Comparison 137.SMT G Final PMA+ vs SMT F Final PMA+
Comparison 138.SMT H Final PMA+ vs SMT F Final PMA+
Comparison 139.SMT I Final PMA+ vs SMT F Final PMA+
Comparison 140.SMT J Final PMA+ vs SMT F Final PMA+
Comparison 141.SMT D Final PMA+ vs SMT B Final PMA+
Comparison 142.SMT E Final PMA+ vs SMT B Final PMA+
Comparison 143.SMT G Final PMA+ vs SMT B Final PMA+
Comparison 144.SMT I Final PMA+ vs SMT B Final PMA+
Comparison 145.SMT D Final PMA+ vs SMT C Final PMA+
Comparison 146.SMT E Final PMA+ vs SMT C Final PMA+
Comparison 147.SMT G Final PMA+ vs SMT C Final PMA+
Comparison 148.SMT I Final PMA+ vs SMT C Final PMA+
Comparison 149.SMT D Final PMA+ vs SMT E Final PMA+
Comparison 150.SMT H Final PMA+ vs SMT J Final PMA+
Comparison 151.SMT J Final PMA+ vs SMT G Final PMA+
Comparison 152.SMT I Final PMA+ vs SMT G Final PMA+
Comparison 153.SMT B Final PMA+ vs SMT C Final PMA+
Comparison 154.SMT A Final PMA+ vs SMT F Final PMA+
Comparison 155.SMT A Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT D Final PMA+ vs SMT E Final PMA+ vs SMT F Final PMA+ vs SMT G Final PMA+ vs SMT H Final PMA+ vs SMT I Final PMA+ vs SMT J Final PMA+
Comparison 156.SMT A Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT D Final PMA+ vs SMT E Final PMA+
Comparison 157.SMT F Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT G Final PMA+ vs SMT I Final PMA+
Comparison 158.SMT B Final PMA- vs SMT A Final PMA-
Comparison 159.SMT C Final PMA- vs SMT A Final PMA-
Comparison 160.SMT D Final PMA- vs SMT A Final PMA-
Comparison 161.SMT E Final PMA- vs SMT A Final PMA-
Comparison 162.SMT G Final PMA- vs SMT F Final PMA-
Comparison 163.SMT H Final PMA- vs SMT F Final PMA-
Comparison 164.SMT I Final PMA- vs SMT F Final PMA-
Comparison 165.SMT J Final PMA- vs SMT F Final PMA-
Comparison 166.SMT D Final PMA- vs SMT B Final PMA-
Comparison 167.SMT E Final PMA- vs SMT B Final PMA-
Comparison 168.SMT G Final PMA- vs SMT B Final PMA-
Comparison 169.SMT I Final PMA- vs SMT B Final PMA-
Comparison 170.SMT D Final PMA- vs SMT C Final PMA-
Comparison 171.SMT E Final PMA- vs SMT C Final PMA-
Comparison 172.SMT G Final PMA- vs SMT C Final PMA-
Comparison 173.SMT I Final PMA- vs SMT C Final PMA-
Comparison 174.SMT D Final PMA- vs SMT E Final PMA-
Comparison 175.SMT H Final PMA- vs SMT J Final PMA-
Comparison 176.SMT J Final PMA- vs SMT G Final PMA-
Comparison 177.SMT I Final PMA- vs SMT G Final PMA-
Comparison 178.SMT B Final PMA- vs SMT C Final PMA-
Comparison 179.SMT A Final PMA- vs SMT F Final PMA-
Comparison 180.SMT A Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT D Final PMA- vs SMT E Final PMA- vs SMT F Final PMA- vs SMT G Final PMA- vs SMT H Final PMA- vs SMT I Final PMA- vs SMT J Final PMA-
Comparison 181.SMT A Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT D Final PMA- vs SMT E Final PMA-
Comparison 182.SMT F Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT G Final PMA- vs SMT I Final PMA-
 
 
 
 
 

LEfSe - Linear Discriminant Analysis Effect Size

LEfSe (Linear Discriminant Analysis Effect Size) is an alternative method to find "organisms, genes, or pathways that consistently explain the differences between two or more microbial communities" (Segata et al., 2011) [14]. Specifically, LEfSe uses rank-based Kruskal-Wallis (KW) sum-rank test to detect features with significant differential (relative) abundance with respect to the class of interest. Since it is rank-based, instead of proportional based, the differential species identified among the comparison groups is less biased (than percent abundance based).

Reference:

  1. Segata N, Izard J, Waldron L, Gevers D, Miropolsky L, Garrett WS, Huttenhower C. Metagenomic biomarker discovery and explanation. Genome Biol. 2011 Jun 24;12(6):R60. doi: 10.1186/gb-2011-12-6-r60. PMID: 21702898; PMCID: PMC3218848.
 
SALIVA Pool 1 PMA+ vs SALIVA Pool 2 PMA+
 
 
 
 
 
 
 
LEfSe Results for All Comparisons
 
Comparison No.Comparison Name
Comparison 1.SALIVA Pool 1 PMA+ vs SALIVA Pool 2 PMA+
Comparison 2.SALIVA Pool 1 PMA- vs SALIVA Pool 2 PMA-
Comparison 3.SALIVA Pool 1 PMA+ vs SALIVA Pool 1 PMA-
Comparison 4.SALIVA Pool 2 PMA+ vs SALIVA Pool 2 PMA-
Comparison 5.SST Saliva P1 PMA+ vs SST Baseline P1 PMA+
Comparison 6.SST Saliva P2 PMA+ vs SST Baseline P2 PMA+
Comparison 7.SST Saliva P1 PMA- vs SST Baseline P1 PMA-
Comparison 8.SST Saliva P2 PMA- vs SST Baseline P2 PMA-
Comparison 9.SST Saliva PMA+ vs SST Baseline PMA+
Comparison 10.SST Saliva PMA- vs SST Baseline PMA-
Comparison 11.SST Baseline PMA+ vs SST Baseline PMA-
Comparison 12.SST Baseline P1 PMA+ vs SST Baseline P2 PMA+
Comparison 13.SST Baseline P1 PMA- vs SST Baseline P2 PMA-
Comparison 14.SST Baseline PMA+ vs SST Final A PMA+
Comparison 15.SST Baseline PMA+ vs SST Final B PMA+
Comparison 16.SST Baseline PMA+ vs SST Final C PMA+
Comparison 17.SST Baseline PMA+ vs SST Final D PMA+
Comparison 18.SST Baseline PMA+ vs SST Final E PMA+
Comparison 19.SST Baseline PMA+ vs SST Final F PMA+
Comparison 20.SST Baseline PMA+ vs SST Final G PMA+
Comparison 21.SST Baseline PMA+ vs SST Final H PMA+
Comparison 22.SST Baseline PMA+ vs SST Final I PMA+
Comparison 23.SST Baseline PMA+ vs SST Final J PMA+
Comparison 24.SST Final A PMA+ vs SST Final A PMA-
Comparison 25.SST Final B PMA+ vs SST Final B PMA-
Comparison 26.SST Final C PMA+ vs SST Final C PMA-
Comparison 27.SST Final D PMA+ vs SST Final D PMA-
Comparison 28.SST Final E PMA+ vs SST Final E PMA-
Comparison 29.SST Final F PMA+ vs SST Final F PMA-
Comparison 30.SST Final G PMA+ vs SST Final G PMA-
Comparison 31.SST Final H PMA+ vs SST Final H PMA-
Comparison 32.SST Final I PMA+ vs SST Final I PMA-
Comparison 33.SST Final J PMA+ vs SST Final J PMA-
Comparison 34.SST Baseline PMA- vs SST Final A PMA-
Comparison 35.SST Baseline PMA- vs SST Final B PMA-
Comparison 36.SST Baseline PMA- vs SST Final C PMA-
Comparison 37.SST Baseline PMA- vs SST Final D PMA-
Comparison 38.SST Baseline PMA- vs SST Final E PMA-
Comparison 39.SST Baseline PMA- vs SST Final F PMA-
Comparison 40.SST Baseline PMA- vs SST Final G PMA-
Comparison 41.SST Baseline PMA- vs SST Final H PMA-
Comparison 42.SST Baseline PMA- vs SST Final I PMA-
Comparison 43.SST Baseline PMA- vs SST Final J PMA-
Comparison 44.SST B Final PMA+ vs SST A Final PMA+
Comparison 45.SST C Final PMA+ vs SST A Final PMA+
Comparison 46.SST D Final PMA+ vs SST A Final PMA+
Comparison 47.SST E Final PMA+ vs SST A Final PMA+
Comparison 48.SST G Final PMA+ vs SST F Final PMA+
Comparison 49.SST H Final PMA+ vs SST F Final PMA+
Comparison 50.SST I Final PMA+ vs SST F Final PMA+
Comparison 51.SST J Final PMA+ vs SST F Final PMA+
Comparison 52.SST D Final PMA+ vs SST B Final PMA+
Comparison 53.SST E Final PMA+ vs SST B Final PMA+
Comparison 54.SST G Final PMA+ vs SST B Final PMA+
Comparison 55.SST I Final PMA+ vs SST B Final PMA+
Comparison 56.SST D Final PMA+ vs SST C Final PMA+
Comparison 57.SST E Final PMA+ vs SST C Final PMA+
Comparison 58.SST G Final PMA+ vs SST C Final PMA+
Comparison 59.SST I Final PMA+ vs SST C Final PMA+
Comparison 60.SST D Final PMA+ vs SST E Final PMA+
Comparison 61.SST H Final PMA+ vs SST J Final PMA+
Comparison 62.SST J Final PMA+ vs SST G Final PMA+
Comparison 63.SST I Final PMA+ vs SST G Final PMA+
Comparison 64.SST B Final PMA+ vs SST C Final PMA+
Comparison 65.SST A Final PMA+ vs SST F Final PMA+
Comparison 66.SST A Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST D Final PMA+ vs SST E Final PMA+ vs SST F Final PMA+ vs SST G Final PMA+ vs SST H Final PMA+ vs SST I Final PMA+ vs SST J Final PMA+
Comparison 67.SST A Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST D Final PMA+ vs SST E Final PMA+
Comparison 68.SST F Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST G Final PMA+ vs SST I Final PMA+
Comparison 69.SST B Final PMA- vs SST A Final PMA-
Comparison 70.SST C Final PMA- vs SST A Final PMA-
Comparison 71.SST D Final PMA- vs SST A Final PMA-
Comparison 72.SST E Final PMA- vs SST A Final PMA-
Comparison 73.SST G Final PMA- vs SST F Final PMA-
Comparison 74.SST H Final PMA- vs SST F Final PMA-
Comparison 75.SST I Final PMA- vs SST F Final PMA-
Comparison 76.SST J Final PMA- vs SST F Final PMA-
Comparison 77.SST D Final PMA- vs SST B Final PMA-
Comparison 78.SST E Final PMA- vs SST B Final PMA-
Comparison 79.SST G Final PMA- vs SST B Final PMA-
Comparison 80.SST I Final PMA- vs SST B Final PMA-
Comparison 81.SST D Final PMA- vs SST C Final PMA-
Comparison 82.SST E Final PMA- vs SST C Final PMA-
Comparison 83.SST G Final PMA- vs SST C Final PMA-
Comparison 84.SST I Final PMA- vs SST C Final PMA-
Comparison 85.SST D Final PMA- vs SST E Final PMA-
Comparison 86.SST H Final PMA- vs SST J Final PMA-
Comparison 87.SST J Final PMA- vs SST G Final PMA-
Comparison 88.SST I Final PMA- vs SST G Final PMA-
Comparison 89.SST B Final PMA- vs SST C Final PMA-
Comparison 90.SST A Final PMA- vs SST F Final PMA-
Comparison 91.SST A Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST D Final PMA- vs SST E Final PMA- vs SST F Final PMA- vs SST G Final PMA- vs SST H Final PMA- vs SST I Final PMA- vs SST J Final PMA-
Comparison 92.SST A Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST D Final PMA- vs SST E Final PMA-
Comparison 93.SST F Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST G Final PMA- vs SST I Final PMA-
Comparison 94.SMT Saliva P1 PMA+ vs SMT Baseline P1 PMA+
Comparison 95.SMT Saliva P2 PMA+ vs SMT Baseline P2 PMA+
Comparison 96.SMT Saliva P1 PMA- vs SMT Baseline P1 PMA-
Comparison 97.SMT Saliva P2 PMA- vs SMT Baseline P2 PMA-
Comparison 98.SMT Saliva PMA+ vs SMT Baseline PMA+
Comparison 99.SMT Saliva PMA- vs SMT Baseline PMA-
Comparison 100.SMT Baseline PMA+ vs SMT Baseline PMA-
Comparison 101.SMT Baseline P1 PMA+ vs SMT Baseline P2 PMA+
Comparison 102.SMT Baseline P1 PMA- vs SMT Baseline P2 PMA-
Comparison 103.SMT Baseline PMA+ vs SMT Final A PMA+
Comparison 104.SMT Baseline PMA+ vs SMT Final B PMA+
Comparison 105.SMT Baseline PMA+ vs SMT Final C PMA+
Comparison 106.SMT Baseline PMA+ vs SMT Final D PMA+
Comparison 107.SMT Baseline PMA+ vs SMT Final E PMA+
Comparison 108.SMT Baseline PMA+ vs SMT Final F PMA+
Comparison 109.SMT Baseline PMA+ vs SMT Final G PMA+
Comparison 110.SMT Baseline PMA+ vs SMT Final H PMA+
Comparison 111.SMT Baseline PMA+ vs SMT Final I PMA+
Comparison 112.SMT Baseline PMA+ vs SMT Final J PMA+
Comparison 113.SMT Final A PMA+ vs SMT Final A PMA-
Comparison 114.SMT Final B PMA+ vs SMT Final B PMA-
Comparison 115.SMT Final C PMA+ vs SMT Final C PMA-
Comparison 116.SMT Final D PMA+ vs SMT Final D PMA-
Comparison 117.SMT Final E PMA+ vs SMT Final E PMA-
Comparison 118.SMT Final F PMA+ vs SMT Final F PMA-
Comparison 119.SMT Final G PMA+ vs SMT Final G PMA-
Comparison 120.SMT Final H PMA+ vs SMT Final H PMA-
Comparison 121.SMT Final I PMA+ vs SMT Final I PMA-
Comparison 122.SMT Final J PMA+ vs SMT Final J PMA-
Comparison 123.SMT Baseline PMA- vs SMT Final A PMA-
Comparison 124.SMT Baseline PMA- vs SMT Final B PMA-
Comparison 125.SMT Baseline PMA- vs SMT Final C PMA-
Comparison 126.SMT Baseline PMA- vs SMT Final D PMA-
Comparison 127.SMT Baseline PMA- vs SMT Final E PMA-
Comparison 128.SMT Baseline PMA- vs SMT Final F PMA-
Comparison 129.SMT Baseline PMA- vs SMT Final G PMA-
Comparison 130.SMT Baseline PMA- vs SMT Final H PMA-
Comparison 131.SMT Baseline PMA- vs SMT Final I PMA-
Comparison 132.SMT Baseline PMA- vs SMT Final J PMA-
Comparison 133.SMT B Final PMA+ vs SMT A Final PMA+
Comparison 134.SMT C Final PMA+ vs SMT A Final PMA+
Comparison 135.SMT D Final PMA+ vs SMT A Final PMA+
Comparison 136.SMT E Final PMA+ vs SMT A Final PMA+
Comparison 137.SMT G Final PMA+ vs SMT F Final PMA+
Comparison 138.SMT H Final PMA+ vs SMT F Final PMA+
Comparison 139.SMT I Final PMA+ vs SMT F Final PMA+
Comparison 140.SMT J Final PMA+ vs SMT F Final PMA+
Comparison 141.SMT D Final PMA+ vs SMT B Final PMA+
Comparison 142.SMT E Final PMA+ vs SMT B Final PMA+
Comparison 143.SMT G Final PMA+ vs SMT B Final PMA+
Comparison 144.SMT I Final PMA+ vs SMT B Final PMA+
Comparison 145.SMT D Final PMA+ vs SMT C Final PMA+
Comparison 146.SMT E Final PMA+ vs SMT C Final PMA+
Comparison 147.SMT G Final PMA+ vs SMT C Final PMA+
Comparison 148.SMT I Final PMA+ vs SMT C Final PMA+
Comparison 149.SMT D Final PMA+ vs SMT E Final PMA+
Comparison 150.SMT H Final PMA+ vs SMT J Final PMA+
Comparison 151.SMT J Final PMA+ vs SMT G Final PMA+
Comparison 152.SMT I Final PMA+ vs SMT G Final PMA+
Comparison 153.SMT B Final PMA+ vs SMT C Final PMA+
Comparison 154.SMT A Final PMA+ vs SMT F Final PMA+
Comparison 155.SMT A Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT D Final PMA+ vs SMT E Final PMA+ vs SMT F Final PMA+ vs SMT G Final PMA+ vs SMT H Final PMA+ vs SMT I Final PMA+ vs SMT J Final PMA+
Comparison 156.SMT A Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT D Final PMA+ vs SMT E Final PMA+
Comparison 157.SMT F Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT G Final PMA+ vs SMT I Final PMA+
Comparison 158.SMT B Final PMA- vs SMT A Final PMA-
Comparison 159.SMT C Final PMA- vs SMT A Final PMA-
Comparison 160.SMT D Final PMA- vs SMT A Final PMA-
Comparison 161.SMT E Final PMA- vs SMT A Final PMA-
Comparison 162.SMT G Final PMA- vs SMT F Final PMA-
Comparison 163.SMT H Final PMA- vs SMT F Final PMA-
Comparison 164.SMT I Final PMA- vs SMT F Final PMA-
Comparison 165.SMT J Final PMA- vs SMT F Final PMA-
Comparison 166.SMT D Final PMA- vs SMT B Final PMA-
Comparison 167.SMT E Final PMA- vs SMT B Final PMA-
Comparison 168.SMT G Final PMA- vs SMT B Final PMA-
Comparison 169.SMT I Final PMA- vs SMT B Final PMA-
Comparison 170.SMT D Final PMA- vs SMT C Final PMA-
Comparison 171.SMT E Final PMA- vs SMT C Final PMA-
Comparison 172.SMT G Final PMA- vs SMT C Final PMA-
Comparison 173.SMT I Final PMA- vs SMT C Final PMA-
Comparison 174.SMT D Final PMA- vs SMT E Final PMA-
Comparison 175.SMT H Final PMA- vs SMT J Final PMA-
Comparison 176.SMT J Final PMA- vs SMT G Final PMA-
Comparison 177.SMT I Final PMA- vs SMT G Final PMA-
Comparison 178.SMT B Final PMA- vs SMT C Final PMA-
Comparison 179.SMT A Final PMA- vs SMT F Final PMA-
Comparison 180.SMT A Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT D Final PMA- vs SMT E Final PMA- vs SMT F Final PMA- vs SMT G Final PMA- vs SMT H Final PMA- vs SMT I Final PMA- vs SMT J Final PMA-
Comparison 181.SMT A Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT D Final PMA- vs SMT E Final PMA-
Comparison 182.SMT F Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT G Final PMA- vs SMT I Final PMA-
 
 

XI. Analysis - Heatmap Profile

 

Species vs Sample Abundance Heatmap for All Samples

 
 
 

Heatmaps for Individual Comparisons

 
A) Two-way clustering - clustered on both columns (Samples) and rows (organism)
Comparison No.Comparison NameFamily LevelGenus LevelSpecies Level
Comparison 1SALIVA Pool 1 PMA+ vs SALIVA Pool 2 PMA+PDFSVGPDFSVGPDFSVG
Comparison 2SALIVA Pool 1 PMA- vs SALIVA Pool 2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 3SALIVA Pool 1 PMA+ vs SALIVA Pool 1 PMA-PDFSVGPDFSVGPDFSVG
Comparison 4SALIVA Pool 2 PMA+ vs SALIVA Pool 2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 5SST Saliva P1 PMA+ vs SST Baseline P1 PMA+PDFSVGPDFSVGPDFSVG
Comparison 6SST Saliva P2 PMA+ vs SST Baseline P2 PMA+PDFSVGPDFSVGPDFSVG
Comparison 7SST Saliva P1 PMA- vs SST Baseline P1 PMA-PDFSVGPDFSVGPDFSVG
Comparison 8SST Saliva P2 PMA- vs SST Baseline P2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 9SST Saliva PMA+ vs SST Baseline PMA+PDFSVGPDFSVGPDFSVG
Comparison 10SST Saliva PMA- vs SST Baseline PMA-PDFSVGPDFSVGPDFSVG
Comparison 11SST Baseline PMA+ vs SST Baseline PMA-PDFSVGPDFSVGPDFSVG
Comparison 12SST Baseline P1 PMA+ vs SST Baseline P2 PMA+PDFSVGPDFSVGPDFSVG
Comparison 13SST Baseline P1 PMA- vs SST Baseline P2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 14SST Baseline PMA+ vs SST Final A PMA+PDFSVGPDFSVGPDFSVG
Comparison 15SST Baseline PMA+ vs SST Final B PMA+PDFSVGPDFSVGPDFSVG
Comparison 16SST Baseline PMA+ vs SST Final C PMA+PDFSVGPDFSVGPDFSVG
Comparison 17SST Baseline PMA+ vs SST Final D PMA+PDFSVGPDFSVGPDFSVG
Comparison 18SST Baseline PMA+ vs SST Final E PMA+PDFSVGPDFSVGPDFSVG
Comparison 19SST Baseline PMA+ vs SST Final F PMA+PDFSVGPDFSVGPDFSVG
Comparison 20SST Baseline PMA+ vs SST Final G PMA+PDFSVGPDFSVGPDFSVG
Comparison 21SST Baseline PMA+ vs SST Final H PMA+PDFSVGPDFSVGPDFSVG
Comparison 22SST Baseline PMA+ vs SST Final I PMA+PDFSVGPDFSVGPDFSVG
Comparison 23SST Baseline PMA+ vs SST Final J PMA+PDFSVGPDFSVGPDFSVG
Comparison 24SST Final A PMA+ vs SST Final A PMA-PDFSVGPDFSVGPDFSVG
Comparison 25SST Final B PMA+ vs SST Final B PMA-PDFSVGPDFSVGPDFSVG
Comparison 26SST Final C PMA+ vs SST Final C PMA-PDFSVGPDFSVGPDFSVG
Comparison 27SST Final D PMA+ vs SST Final D PMA-PDFSVGPDFSVGPDFSVG
Comparison 28SST Final E PMA+ vs SST Final E PMA-PDFSVGPDFSVGPDFSVG
Comparison 29SST Final F PMA+ vs SST Final F PMA-PDFSVGPDFSVGPDFSVG
Comparison 30SST Final G PMA+ vs SST Final G PMA-PDFSVGPDFSVGPDFSVG
Comparison 31SST Final H PMA+ vs SST Final H PMA-PDFSVGPDFSVGPDFSVG
Comparison 32SST Final I PMA+ vs SST Final I PMA-PDFSVGPDFSVGPDFSVG
Comparison 33SST Final J PMA+ vs SST Final J PMA-PDFSVGPDFSVGPDFSVG
Comparison 34SST Baseline PMA- vs SST Final A PMA-PDFSVGPDFSVGPDFSVG
Comparison 35SST Baseline PMA- vs SST Final B PMA-PDFSVGPDFSVGPDFSVG
Comparison 36SST Baseline PMA- vs SST Final C PMA-PDFSVGPDFSVGPDFSVG
Comparison 37SST Baseline PMA- vs SST Final D PMA-PDFSVGPDFSVGPDFSVG
Comparison 38SST Baseline PMA- vs SST Final E PMA-PDFSVGPDFSVGPDFSVG
Comparison 39SST Baseline PMA- vs SST Final F PMA-PDFSVGPDFSVGPDFSVG
Comparison 40SST Baseline PMA- vs SST Final G PMA-PDFSVGPDFSVGPDFSVG
Comparison 41SST Baseline PMA- vs SST Final H PMA-PDFSVGPDFSVGPDFSVG
Comparison 42SST Baseline PMA- vs SST Final I PMA-PDFSVGPDFSVGPDFSVG
Comparison 43SST Baseline PMA- vs SST Final J PMA-PDFSVGPDFSVGPDFSVG
Comparison 44SST B Final PMA+ vs SST A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 45SST C Final PMA+ vs SST A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 46SST D Final PMA+ vs SST A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 47SST E Final PMA+ vs SST A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 48SST G Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 49SST H Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 50SST I Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 51SST J Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 52SST D Final PMA+ vs SST B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 53SST E Final PMA+ vs SST B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 54SST G Final PMA+ vs SST B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 55SST I Final PMA+ vs SST B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 56SST D Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 57SST E Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 58SST G Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 59SST I Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 60SST D Final PMA+ vs SST E Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 61SST H Final PMA+ vs SST J Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 62SST J Final PMA+ vs SST G Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 63SST I Final PMA+ vs SST G Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 64SST B Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 65SST A Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 66SST A Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST D Final PMA+ vs SST E Final PMA+ vs SST F Final PMA+ vs SST G Final PMA+ vs SST H Final PMA+ vs SST I Final PMA+ vs SST J Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 67SST A Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST D Final PMA+ vs SST E Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 68SST F Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST G Final PMA+ vs SST I Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 69SST B Final PMA- vs SST A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 70SST C Final PMA- vs SST A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 71SST D Final PMA- vs SST A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 72SST E Final PMA- vs SST A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 73SST G Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 74SST H Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 75SST I Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 76SST J Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 77SST D Final PMA- vs SST B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 78SST E Final PMA- vs SST B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 79SST G Final PMA- vs SST B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 80SST I Final PMA- vs SST B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 81SST D Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 82SST E Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 83SST G Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 84SST I Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 85SST D Final PMA- vs SST E Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 86SST H Final PMA- vs SST J Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 87SST J Final PMA- vs SST G Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 88SST I Final PMA- vs SST G Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 89SST B Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 90SST A Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 91SST A Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST D Final PMA- vs SST E Final PMA- vs SST F Final PMA- vs SST G Final PMA- vs SST H Final PMA- vs SST I Final PMA- vs SST J Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 92SST A Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST D Final PMA- vs SST E Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 93SST F Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST G Final PMA- vs SST I Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 94SMT Saliva P1 PMA+ vs SMT Baseline P1 PMA+PDFSVGPDFSVGPDFSVG
Comparison 95SMT Saliva P2 PMA+ vs SMT Baseline P2 PMA+PDFSVGPDFSVGPDFSVG
Comparison 96SMT Saliva P1 PMA- vs SMT Baseline P1 PMA-PDFSVGPDFSVGPDFSVG
Comparison 97SMT Saliva P2 PMA- vs SMT Baseline P2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 98SMT Saliva PMA+ vs SMT Baseline PMA+PDFSVGPDFSVGPDFSVG
Comparison 99SMT Saliva PMA- vs SMT Baseline PMA-PDFSVGPDFSVGPDFSVG
Comparison 100SMT Baseline PMA+ vs SMT Baseline PMA-PDFSVGPDFSVGPDFSVG
Comparison 101SMT Baseline P1 PMA+ vs SMT Baseline P2 PMA+PDFSVGPDFSVGPDFSVG
Comparison 102SMT Baseline P1 PMA- vs SMT Baseline P2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 103SMT Baseline PMA+ vs SMT Final A PMA+PDFSVGPDFSVGPDFSVG
Comparison 104SMT Baseline PMA+ vs SMT Final B PMA+PDFSVGPDFSVGPDFSVG
Comparison 105SMT Baseline PMA+ vs SMT Final C PMA+PDFSVGPDFSVGPDFSVG
Comparison 106SMT Baseline PMA+ vs SMT Final D PMA+PDFSVGPDFSVGPDFSVG
Comparison 107SMT Baseline PMA+ vs SMT Final E PMA+PDFSVGPDFSVGPDFSVG
Comparison 108SMT Baseline PMA+ vs SMT Final F PMA+PDFSVGPDFSVGPDFSVG
Comparison 109SMT Baseline PMA+ vs SMT Final G PMA+PDFSVGPDFSVGPDFSVG
Comparison 110SMT Baseline PMA+ vs SMT Final H PMA+PDFSVGPDFSVGPDFSVG
Comparison 111SMT Baseline PMA+ vs SMT Final I PMA+PDFSVGPDFSVGPDFSVG
Comparison 112SMT Baseline PMA+ vs SMT Final J PMA+PDFSVGPDFSVGPDFSVG
Comparison 113SMT Final A PMA+ vs SMT Final A PMA-PDFSVGPDFSVGPDFSVG
Comparison 114SMT Final B PMA+ vs SMT Final B PMA-PDFSVGPDFSVGPDFSVG
Comparison 115SMT Final C PMA+ vs SMT Final C PMA-PDFSVGPDFSVGPDFSVG
Comparison 116SMT Final D PMA+ vs SMT Final D PMA-PDFSVGPDFSVGPDFSVG
Comparison 117SMT Final E PMA+ vs SMT Final E PMA-PDFSVGPDFSVGPDFSVG
Comparison 118SMT Final F PMA+ vs SMT Final F PMA-PDFSVGPDFSVGPDFSVG
Comparison 119SMT Final G PMA+ vs SMT Final G PMA-PDFSVGPDFSVGPDFSVG
Comparison 120SMT Final H PMA+ vs SMT Final H PMA-PDFSVGPDFSVGPDFSVG
Comparison 121SMT Final I PMA+ vs SMT Final I PMA-PDFSVGPDFSVGPDFSVG
Comparison 122SMT Final J PMA+ vs SMT Final J PMA-PDFSVGPDFSVGPDFSVG
Comparison 123SMT Baseline PMA- vs SMT Final A PMA-PDFSVGPDFSVGPDFSVG
Comparison 124SMT Baseline PMA- vs SMT Final B PMA-PDFSVGPDFSVGPDFSVG
Comparison 125SMT Baseline PMA- vs SMT Final C PMA-PDFSVGPDFSVGPDFSVG
Comparison 126SMT Baseline PMA- vs SMT Final D PMA-PDFSVGPDFSVGPDFSVG
Comparison 127SMT Baseline PMA- vs SMT Final E PMA-PDFSVGPDFSVGPDFSVG
Comparison 128SMT Baseline PMA- vs SMT Final F PMA-PDFSVGPDFSVGPDFSVG
Comparison 129SMT Baseline PMA- vs SMT Final G PMA-PDFSVGPDFSVGPDFSVG
Comparison 130SMT Baseline PMA- vs SMT Final H PMA-PDFSVGPDFSVGPDFSVG
Comparison 131SMT Baseline PMA- vs SMT Final I PMA-PDFSVGPDFSVGPDFSVG
Comparison 132SMT Baseline PMA- vs SMT Final J PMA-PDFSVGPDFSVGPDFSVG
Comparison 133SMT B Final PMA+ vs SMT A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 134SMT C Final PMA+ vs SMT A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 135SMT D Final PMA+ vs SMT A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 136SMT E Final PMA+ vs SMT A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 137SMT G Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 138SMT H Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 139SMT I Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 140SMT J Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 141SMT D Final PMA+ vs SMT B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 142SMT E Final PMA+ vs SMT B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 143SMT G Final PMA+ vs SMT B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 144SMT I Final PMA+ vs SMT B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 145SMT D Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 146SMT E Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 147SMT G Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 148SMT I Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 149SMT D Final PMA+ vs SMT E Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 150SMT H Final PMA+ vs SMT J Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 151SMT J Final PMA+ vs SMT G Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 152SMT I Final PMA+ vs SMT G Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 153SMT B Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 154SMT A Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 155SMT A Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT D Final PMA+ vs SMT E Final PMA+ vs SMT F Final PMA+ vs SMT G Final PMA+ vs SMT H Final PMA+ vs SMT I Final PMA+ vs SMT J Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 156SMT A Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT D Final PMA+ vs SMT E Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 157SMT F Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT G Final PMA+ vs SMT I Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 158SMT B Final PMA- vs SMT A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 159SMT C Final PMA- vs SMT A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 160SMT D Final PMA- vs SMT A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 161SMT E Final PMA- vs SMT A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 162SMT G Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 163SMT H Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 164SMT I Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 165SMT J Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 166SMT D Final PMA- vs SMT B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 167SMT E Final PMA- vs SMT B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 168SMT G Final PMA- vs SMT B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 169SMT I Final PMA- vs SMT B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 170SMT D Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 171SMT E Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 172SMT G Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 173SMT I Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 174SMT D Final PMA- vs SMT E Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 175SMT H Final PMA- vs SMT J Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 176SMT J Final PMA- vs SMT G Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 177SMT I Final PMA- vs SMT G Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 178SMT B Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 179SMT A Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 180SMT A Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT D Final PMA- vs SMT E Final PMA- vs SMT F Final PMA- vs SMT G Final PMA- vs SMT H Final PMA- vs SMT I Final PMA- vs SMT J Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 181SMT A Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT D Final PMA- vs SMT E Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 182SMT F Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT G Final PMA- vs SMT I Final PMA-PDFSVGPDFSVGPDFSVG
 
 
B) One-way clustering - clustered on rows (organism) only
Comparison No.Comparison NameFamily LevelGenus LevelSpecies Level
Comparison 1SALIVA Pool 1 PMA+ vs SALIVA Pool 2 PMA+PDFSVGPDFSVGPDFSVG
Comparison 2SALIVA Pool 1 PMA- vs SALIVA Pool 2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 3SALIVA Pool 1 PMA+ vs SALIVA Pool 1 PMA-PDFSVGPDFSVGPDFSVG
Comparison 4SALIVA Pool 2 PMA+ vs SALIVA Pool 2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 5SST Saliva P1 PMA+ vs SST Baseline P1 PMA+PDFSVGPDFSVGPDFSVG
Comparison 6SST Saliva P2 PMA+ vs SST Baseline P2 PMA+PDFSVGPDFSVGPDFSVG
Comparison 7SST Saliva P1 PMA- vs SST Baseline P1 PMA-PDFSVGPDFSVGPDFSVG
Comparison 8SST Saliva P2 PMA- vs SST Baseline P2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 9SST Saliva PMA+ vs SST Baseline PMA+PDFSVGPDFSVGPDFSVG
Comparison 10SST Saliva PMA- vs SST Baseline PMA-PDFSVGPDFSVGPDFSVG
Comparison 11SST Baseline PMA+ vs SST Baseline PMA-PDFSVGPDFSVGPDFSVG
Comparison 12SST Baseline P1 PMA+ vs SST Baseline P2 PMA+PDFSVGPDFSVGPDFSVG
Comparison 13SST Baseline P1 PMA- vs SST Baseline P2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 14SST Baseline PMA+ vs SST Final A PMA+PDFSVGPDFSVGPDFSVG
Comparison 15SST Baseline PMA+ vs SST Final B PMA+PDFSVGPDFSVGPDFSVG
Comparison 16SST Baseline PMA+ vs SST Final C PMA+PDFSVGPDFSVGPDFSVG
Comparison 17SST Baseline PMA+ vs SST Final D PMA+PDFSVGPDFSVGPDFSVG
Comparison 18SST Baseline PMA+ vs SST Final E PMA+PDFSVGPDFSVGPDFSVG
Comparison 19SST Baseline PMA+ vs SST Final F PMA+PDFSVGPDFSVGPDFSVG
Comparison 20SST Baseline PMA+ vs SST Final G PMA+PDFSVGPDFSVGPDFSVG
Comparison 21SST Baseline PMA+ vs SST Final H PMA+PDFSVGPDFSVGPDFSVG
Comparison 22SST Baseline PMA+ vs SST Final I PMA+PDFSVGPDFSVGPDFSVG
Comparison 23SST Baseline PMA+ vs SST Final J PMA+PDFSVGPDFSVGPDFSVG
Comparison 24SST Final A PMA+ vs SST Final A PMA-PDFSVGPDFSVGPDFSVG
Comparison 25SST Final B PMA+ vs SST Final B PMA-PDFSVGPDFSVGPDFSVG
Comparison 26SST Final C PMA+ vs SST Final C PMA-PDFSVGPDFSVGPDFSVG
Comparison 27SST Final D PMA+ vs SST Final D PMA-PDFSVGPDFSVGPDFSVG
Comparison 28SST Final E PMA+ vs SST Final E PMA-PDFSVGPDFSVGPDFSVG
Comparison 29SST Final F PMA+ vs SST Final F PMA-PDFSVGPDFSVGPDFSVG
Comparison 30SST Final G PMA+ vs SST Final G PMA-PDFSVGPDFSVGPDFSVG
Comparison 31SST Final H PMA+ vs SST Final H PMA-PDFSVGPDFSVGPDFSVG
Comparison 32SST Final I PMA+ vs SST Final I PMA-PDFSVGPDFSVGPDFSVG
Comparison 33SST Final J PMA+ vs SST Final J PMA-PDFSVGPDFSVGPDFSVG
Comparison 34SST Baseline PMA- vs SST Final A PMA-PDFSVGPDFSVGPDFSVG
Comparison 35SST Baseline PMA- vs SST Final B PMA-PDFSVGPDFSVGPDFSVG
Comparison 36SST Baseline PMA- vs SST Final C PMA-PDFSVGPDFSVGPDFSVG
Comparison 37SST Baseline PMA- vs SST Final D PMA-PDFSVGPDFSVGPDFSVG
Comparison 38SST Baseline PMA- vs SST Final E PMA-PDFSVGPDFSVGPDFSVG
Comparison 39SST Baseline PMA- vs SST Final F PMA-PDFSVGPDFSVGPDFSVG
Comparison 40SST Baseline PMA- vs SST Final G PMA-PDFSVGPDFSVGPDFSVG
Comparison 41SST Baseline PMA- vs SST Final H PMA-PDFSVGPDFSVGPDFSVG
Comparison 42SST Baseline PMA- vs SST Final I PMA-PDFSVGPDFSVGPDFSVG
Comparison 43SST Baseline PMA- vs SST Final J PMA-PDFSVGPDFSVGPDFSVG
Comparison 44SST B Final PMA+ vs SST A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 45SST C Final PMA+ vs SST A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 46SST D Final PMA+ vs SST A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 47SST E Final PMA+ vs SST A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 48SST G Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 49SST H Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 50SST I Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 51SST J Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 52SST D Final PMA+ vs SST B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 53SST E Final PMA+ vs SST B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 54SST G Final PMA+ vs SST B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 55SST I Final PMA+ vs SST B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 56SST D Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 57SST E Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 58SST G Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 59SST I Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 60SST D Final PMA+ vs SST E Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 61SST H Final PMA+ vs SST J Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 62SST J Final PMA+ vs SST G Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 63SST I Final PMA+ vs SST G Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 64SST B Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 65SST A Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 66SST A Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST D Final PMA+ vs SST E Final PMA+ vs SST F Final PMA+ vs SST G Final PMA+ vs SST H Final PMA+ vs SST I Final PMA+ vs SST J Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 67SST A Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST D Final PMA+ vs SST E Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 68SST F Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST G Final PMA+ vs SST I Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 69SST B Final PMA- vs SST A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 70SST C Final PMA- vs SST A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 71SST D Final PMA- vs SST A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 72SST E Final PMA- vs SST A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 73SST G Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 74SST H Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 75SST I Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 76SST J Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 77SST D Final PMA- vs SST B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 78SST E Final PMA- vs SST B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 79SST G Final PMA- vs SST B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 80SST I Final PMA- vs SST B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 81SST D Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 82SST E Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 83SST G Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 84SST I Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 85SST D Final PMA- vs SST E Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 86SST H Final PMA- vs SST J Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 87SST J Final PMA- vs SST G Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 88SST I Final PMA- vs SST G Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 89SST B Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 90SST A Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 91SST A Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST D Final PMA- vs SST E Final PMA- vs SST F Final PMA- vs SST G Final PMA- vs SST H Final PMA- vs SST I Final PMA- vs SST J Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 92SST A Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST D Final PMA- vs SST E Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 93SST F Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST G Final PMA- vs SST I Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 94SMT Saliva P1 PMA+ vs SMT Baseline P1 PMA+PDFSVGPDFSVGPDFSVG
Comparison 95SMT Saliva P2 PMA+ vs SMT Baseline P2 PMA+PDFSVGPDFSVGPDFSVG
Comparison 96SMT Saliva P1 PMA- vs SMT Baseline P1 PMA-PDFSVGPDFSVGPDFSVG
Comparison 97SMT Saliva P2 PMA- vs SMT Baseline P2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 98SMT Saliva PMA+ vs SMT Baseline PMA+PDFSVGPDFSVGPDFSVG
Comparison 99SMT Saliva PMA- vs SMT Baseline PMA-PDFSVGPDFSVGPDFSVG
Comparison 100SMT Baseline PMA+ vs SMT Baseline PMA-PDFSVGPDFSVGPDFSVG
Comparison 101SMT Baseline P1 PMA+ vs SMT Baseline P2 PMA+PDFSVGPDFSVGPDFSVG
Comparison 102SMT Baseline P1 PMA- vs SMT Baseline P2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 103SMT Baseline PMA+ vs SMT Final A PMA+PDFSVGPDFSVGPDFSVG
Comparison 104SMT Baseline PMA+ vs SMT Final B PMA+PDFSVGPDFSVGPDFSVG
Comparison 105SMT Baseline PMA+ vs SMT Final C PMA+PDFSVGPDFSVGPDFSVG
Comparison 106SMT Baseline PMA+ vs SMT Final D PMA+PDFSVGPDFSVGPDFSVG
Comparison 107SMT Baseline PMA+ vs SMT Final E PMA+PDFSVGPDFSVGPDFSVG
Comparison 108SMT Baseline PMA+ vs SMT Final F PMA+PDFSVGPDFSVGPDFSVG
Comparison 109SMT Baseline PMA+ vs SMT Final G PMA+PDFSVGPDFSVGPDFSVG
Comparison 110SMT Baseline PMA+ vs SMT Final H PMA+PDFSVGPDFSVGPDFSVG
Comparison 111SMT Baseline PMA+ vs SMT Final I PMA+PDFSVGPDFSVGPDFSVG
Comparison 112SMT Baseline PMA+ vs SMT Final J PMA+PDFSVGPDFSVGPDFSVG
Comparison 113SMT Final A PMA+ vs SMT Final A PMA-PDFSVGPDFSVGPDFSVG
Comparison 114SMT Final B PMA+ vs SMT Final B PMA-PDFSVGPDFSVGPDFSVG
Comparison 115SMT Final C PMA+ vs SMT Final C PMA-PDFSVGPDFSVGPDFSVG
Comparison 116SMT Final D PMA+ vs SMT Final D PMA-PDFSVGPDFSVGPDFSVG
Comparison 117SMT Final E PMA+ vs SMT Final E PMA-PDFSVGPDFSVGPDFSVG
Comparison 118SMT Final F PMA+ vs SMT Final F PMA-PDFSVGPDFSVGPDFSVG
Comparison 119SMT Final G PMA+ vs SMT Final G PMA-PDFSVGPDFSVGPDFSVG
Comparison 120SMT Final H PMA+ vs SMT Final H PMA-PDFSVGPDFSVGPDFSVG
Comparison 121SMT Final I PMA+ vs SMT Final I PMA-PDFSVGPDFSVGPDFSVG
Comparison 122SMT Final J PMA+ vs SMT Final J PMA-PDFSVGPDFSVGPDFSVG
Comparison 123SMT Baseline PMA- vs SMT Final A PMA-PDFSVGPDFSVGPDFSVG
Comparison 124SMT Baseline PMA- vs SMT Final B PMA-PDFSVGPDFSVGPDFSVG
Comparison 125SMT Baseline PMA- vs SMT Final C PMA-PDFSVGPDFSVGPDFSVG
Comparison 126SMT Baseline PMA- vs SMT Final D PMA-PDFSVGPDFSVGPDFSVG
Comparison 127SMT Baseline PMA- vs SMT Final E PMA-PDFSVGPDFSVGPDFSVG
Comparison 128SMT Baseline PMA- vs SMT Final F PMA-PDFSVGPDFSVGPDFSVG
Comparison 129SMT Baseline PMA- vs SMT Final G PMA-PDFSVGPDFSVGPDFSVG
Comparison 130SMT Baseline PMA- vs SMT Final H PMA-PDFSVGPDFSVGPDFSVG
Comparison 131SMT Baseline PMA- vs SMT Final I PMA-PDFSVGPDFSVGPDFSVG
Comparison 132SMT Baseline PMA- vs SMT Final J PMA-PDFSVGPDFSVGPDFSVG
Comparison 133SMT B Final PMA+ vs SMT A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 134SMT C Final PMA+ vs SMT A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 135SMT D Final PMA+ vs SMT A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 136SMT E Final PMA+ vs SMT A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 137SMT G Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 138SMT H Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 139SMT I Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 140SMT J Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 141SMT D Final PMA+ vs SMT B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 142SMT E Final PMA+ vs SMT B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 143SMT G Final PMA+ vs SMT B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 144SMT I Final PMA+ vs SMT B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 145SMT D Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 146SMT E Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 147SMT G Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 148SMT I Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 149SMT D Final PMA+ vs SMT E Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 150SMT H Final PMA+ vs SMT J Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 151SMT J Final PMA+ vs SMT G Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 152SMT I Final PMA+ vs SMT G Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 153SMT B Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 154SMT A Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 155SMT A Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT D Final PMA+ vs SMT E Final PMA+ vs SMT F Final PMA+ vs SMT G Final PMA+ vs SMT H Final PMA+ vs SMT I Final PMA+ vs SMT J Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 156SMT A Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT D Final PMA+ vs SMT E Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 157SMT F Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT G Final PMA+ vs SMT I Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 158SMT B Final PMA- vs SMT A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 159SMT C Final PMA- vs SMT A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 160SMT D Final PMA- vs SMT A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 161SMT E Final PMA- vs SMT A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 162SMT G Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 163SMT H Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 164SMT I Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 165SMT J Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 166SMT D Final PMA- vs SMT B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 167SMT E Final PMA- vs SMT B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 168SMT G Final PMA- vs SMT B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 169SMT I Final PMA- vs SMT B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 170SMT D Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 171SMT E Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 172SMT G Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 173SMT I Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 174SMT D Final PMA- vs SMT E Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 175SMT H Final PMA- vs SMT J Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 176SMT J Final PMA- vs SMT G Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 177SMT I Final PMA- vs SMT G Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 178SMT B Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 179SMT A Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 180SMT A Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT D Final PMA- vs SMT E Final PMA- vs SMT F Final PMA- vs SMT G Final PMA- vs SMT H Final PMA- vs SMT I Final PMA- vs SMT J Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 181SMT A Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT D Final PMA- vs SMT E Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 182SMT F Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT G Final PMA- vs SMT I Final PMA-PDFSVGPDFSVGPDFSVG
 
 
C) No clustering
Comparison No.Comparison NameFamily LevelGenus LevelSpecies Level
Comparison 1SALIVA Pool 1 PMA+ vs SALIVA Pool 2 PMA+PDFSVGPDFSVGPDFSVG
Comparison 2SALIVA Pool 1 PMA- vs SALIVA Pool 2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 3SALIVA Pool 1 PMA+ vs SALIVA Pool 1 PMA-PDFSVGPDFSVGPDFSVG
Comparison 4SALIVA Pool 2 PMA+ vs SALIVA Pool 2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 5SST Saliva P1 PMA+ vs SST Baseline P1 PMA+PDFSVGPDFSVGPDFSVG
Comparison 6SST Saliva P2 PMA+ vs SST Baseline P2 PMA+PDFSVGPDFSVGPDFSVG
Comparison 7SST Saliva P1 PMA- vs SST Baseline P1 PMA-PDFSVGPDFSVGPDFSVG
Comparison 8SST Saliva P2 PMA- vs SST Baseline P2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 9SST Saliva PMA+ vs SST Baseline PMA+PDFSVGPDFSVGPDFSVG
Comparison 10SST Saliva PMA- vs SST Baseline PMA-PDFSVGPDFSVGPDFSVG
Comparison 11SST Baseline PMA+ vs SST Baseline PMA-PDFSVGPDFSVGPDFSVG
Comparison 12SST Baseline P1 PMA+ vs SST Baseline P2 PMA+PDFSVGPDFSVGPDFSVG
Comparison 13SST Baseline P1 PMA- vs SST Baseline P2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 14SST Baseline PMA+ vs SST Final A PMA+PDFSVGPDFSVGPDFSVG
Comparison 15SST Baseline PMA+ vs SST Final B PMA+PDFSVGPDFSVGPDFSVG
Comparison 16SST Baseline PMA+ vs SST Final C PMA+PDFSVGPDFSVGPDFSVG
Comparison 17SST Baseline PMA+ vs SST Final D PMA+PDFSVGPDFSVGPDFSVG
Comparison 18SST Baseline PMA+ vs SST Final E PMA+PDFSVGPDFSVGPDFSVG
Comparison 19SST Baseline PMA+ vs SST Final F PMA+PDFSVGPDFSVGPDFSVG
Comparison 20SST Baseline PMA+ vs SST Final G PMA+PDFSVGPDFSVGPDFSVG
Comparison 21SST Baseline PMA+ vs SST Final H PMA+PDFSVGPDFSVGPDFSVG
Comparison 22SST Baseline PMA+ vs SST Final I PMA+PDFSVGPDFSVGPDFSVG
Comparison 23SST Baseline PMA+ vs SST Final J PMA+PDFSVGPDFSVGPDFSVG
Comparison 24SST Final A PMA+ vs SST Final A PMA-PDFSVGPDFSVGPDFSVG
Comparison 25SST Final B PMA+ vs SST Final B PMA-PDFSVGPDFSVGPDFSVG
Comparison 26SST Final C PMA+ vs SST Final C PMA-PDFSVGPDFSVGPDFSVG
Comparison 27SST Final D PMA+ vs SST Final D PMA-PDFSVGPDFSVGPDFSVG
Comparison 28SST Final E PMA+ vs SST Final E PMA-PDFSVGPDFSVGPDFSVG
Comparison 29SST Final F PMA+ vs SST Final F PMA-PDFSVGPDFSVGPDFSVG
Comparison 30SST Final G PMA+ vs SST Final G PMA-PDFSVGPDFSVGPDFSVG
Comparison 31SST Final H PMA+ vs SST Final H PMA-PDFSVGPDFSVGPDFSVG
Comparison 32SST Final I PMA+ vs SST Final I PMA-PDFSVGPDFSVGPDFSVG
Comparison 33SST Final J PMA+ vs SST Final J PMA-PDFSVGPDFSVGPDFSVG
Comparison 34SST Baseline PMA- vs SST Final A PMA-PDFSVGPDFSVGPDFSVG
Comparison 35SST Baseline PMA- vs SST Final B PMA-PDFSVGPDFSVGPDFSVG
Comparison 36SST Baseline PMA- vs SST Final C PMA-PDFSVGPDFSVGPDFSVG
Comparison 37SST Baseline PMA- vs SST Final D PMA-PDFSVGPDFSVGPDFSVG
Comparison 38SST Baseline PMA- vs SST Final E PMA-PDFSVGPDFSVGPDFSVG
Comparison 39SST Baseline PMA- vs SST Final F PMA-PDFSVGPDFSVGPDFSVG
Comparison 40SST Baseline PMA- vs SST Final G PMA-PDFSVGPDFSVGPDFSVG
Comparison 41SST Baseline PMA- vs SST Final H PMA-PDFSVGPDFSVGPDFSVG
Comparison 42SST Baseline PMA- vs SST Final I PMA-PDFSVGPDFSVGPDFSVG
Comparison 43SST Baseline PMA- vs SST Final J PMA-PDFSVGPDFSVGPDFSVG
Comparison 44SST B Final PMA+ vs SST A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 45SST C Final PMA+ vs SST A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 46SST D Final PMA+ vs SST A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 47SST E Final PMA+ vs SST A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 48SST G Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 49SST H Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 50SST I Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 51SST J Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 52SST D Final PMA+ vs SST B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 53SST E Final PMA+ vs SST B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 54SST G Final PMA+ vs SST B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 55SST I Final PMA+ vs SST B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 56SST D Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 57SST E Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 58SST G Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 59SST I Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 60SST D Final PMA+ vs SST E Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 61SST H Final PMA+ vs SST J Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 62SST J Final PMA+ vs SST G Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 63SST I Final PMA+ vs SST G Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 64SST B Final PMA+ vs SST C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 65SST A Final PMA+ vs SST F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 66SST A Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST D Final PMA+ vs SST E Final PMA+ vs SST F Final PMA+ vs SST G Final PMA+ vs SST H Final PMA+ vs SST I Final PMA+ vs SST J Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 67SST A Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST D Final PMA+ vs SST E Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 68SST F Final PMA+ vs SST B Final PMA+ vs SST C Final PMA+ vs SST G Final PMA+ vs SST I Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 69SST B Final PMA- vs SST A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 70SST C Final PMA- vs SST A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 71SST D Final PMA- vs SST A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 72SST E Final PMA- vs SST A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 73SST G Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 74SST H Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 75SST I Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 76SST J Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 77SST D Final PMA- vs SST B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 78SST E Final PMA- vs SST B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 79SST G Final PMA- vs SST B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 80SST I Final PMA- vs SST B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 81SST D Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 82SST E Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 83SST G Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 84SST I Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 85SST D Final PMA- vs SST E Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 86SST H Final PMA- vs SST J Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 87SST J Final PMA- vs SST G Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 88SST I Final PMA- vs SST G Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 89SST B Final PMA- vs SST C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 90SST A Final PMA- vs SST F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 91SST A Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST D Final PMA- vs SST E Final PMA- vs SST F Final PMA- vs SST G Final PMA- vs SST H Final PMA- vs SST I Final PMA- vs SST J Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 92SST A Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST D Final PMA- vs SST E Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 93SST F Final PMA- vs SST B Final PMA- vs SST C Final PMA- vs SST G Final PMA- vs SST I Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 94SMT Saliva P1 PMA+ vs SMT Baseline P1 PMA+PDFSVGPDFSVGPDFSVG
Comparison 95SMT Saliva P2 PMA+ vs SMT Baseline P2 PMA+PDFSVGPDFSVGPDFSVG
Comparison 96SMT Saliva P1 PMA- vs SMT Baseline P1 PMA-PDFSVGPDFSVGPDFSVG
Comparison 97SMT Saliva P2 PMA- vs SMT Baseline P2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 98SMT Saliva PMA+ vs SMT Baseline PMA+PDFSVGPDFSVGPDFSVG
Comparison 99SMT Saliva PMA- vs SMT Baseline PMA-PDFSVGPDFSVGPDFSVG
Comparison 100SMT Baseline PMA+ vs SMT Baseline PMA-PDFSVGPDFSVGPDFSVG
Comparison 101SMT Baseline P1 PMA+ vs SMT Baseline P2 PMA+PDFSVGPDFSVGPDFSVG
Comparison 102SMT Baseline P1 PMA- vs SMT Baseline P2 PMA-PDFSVGPDFSVGPDFSVG
Comparison 103SMT Baseline PMA+ vs SMT Final A PMA+PDFSVGPDFSVGPDFSVG
Comparison 104SMT Baseline PMA+ vs SMT Final B PMA+PDFSVGPDFSVGPDFSVG
Comparison 105SMT Baseline PMA+ vs SMT Final C PMA+PDFSVGPDFSVGPDFSVG
Comparison 106SMT Baseline PMA+ vs SMT Final D PMA+PDFSVGPDFSVGPDFSVG
Comparison 107SMT Baseline PMA+ vs SMT Final E PMA+PDFSVGPDFSVGPDFSVG
Comparison 108SMT Baseline PMA+ vs SMT Final F PMA+PDFSVGPDFSVGPDFSVG
Comparison 109SMT Baseline PMA+ vs SMT Final G PMA+PDFSVGPDFSVGPDFSVG
Comparison 110SMT Baseline PMA+ vs SMT Final H PMA+PDFSVGPDFSVGPDFSVG
Comparison 111SMT Baseline PMA+ vs SMT Final I PMA+PDFSVGPDFSVGPDFSVG
Comparison 112SMT Baseline PMA+ vs SMT Final J PMA+PDFSVGPDFSVGPDFSVG
Comparison 113SMT Final A PMA+ vs SMT Final A PMA-PDFSVGPDFSVGPDFSVG
Comparison 114SMT Final B PMA+ vs SMT Final B PMA-PDFSVGPDFSVGPDFSVG
Comparison 115SMT Final C PMA+ vs SMT Final C PMA-PDFSVGPDFSVGPDFSVG
Comparison 116SMT Final D PMA+ vs SMT Final D PMA-PDFSVGPDFSVGPDFSVG
Comparison 117SMT Final E PMA+ vs SMT Final E PMA-PDFSVGPDFSVGPDFSVG
Comparison 118SMT Final F PMA+ vs SMT Final F PMA-PDFSVGPDFSVGPDFSVG
Comparison 119SMT Final G PMA+ vs SMT Final G PMA-PDFSVGPDFSVGPDFSVG
Comparison 120SMT Final H PMA+ vs SMT Final H PMA-PDFSVGPDFSVGPDFSVG
Comparison 121SMT Final I PMA+ vs SMT Final I PMA-PDFSVGPDFSVGPDFSVG
Comparison 122SMT Final J PMA+ vs SMT Final J PMA-PDFSVGPDFSVGPDFSVG
Comparison 123SMT Baseline PMA- vs SMT Final A PMA-PDFSVGPDFSVGPDFSVG
Comparison 124SMT Baseline PMA- vs SMT Final B PMA-PDFSVGPDFSVGPDFSVG
Comparison 125SMT Baseline PMA- vs SMT Final C PMA-PDFSVGPDFSVGPDFSVG
Comparison 126SMT Baseline PMA- vs SMT Final D PMA-PDFSVGPDFSVGPDFSVG
Comparison 127SMT Baseline PMA- vs SMT Final E PMA-PDFSVGPDFSVGPDFSVG
Comparison 128SMT Baseline PMA- vs SMT Final F PMA-PDFSVGPDFSVGPDFSVG
Comparison 129SMT Baseline PMA- vs SMT Final G PMA-PDFSVGPDFSVGPDFSVG
Comparison 130SMT Baseline PMA- vs SMT Final H PMA-PDFSVGPDFSVGPDFSVG
Comparison 131SMT Baseline PMA- vs SMT Final I PMA-PDFSVGPDFSVGPDFSVG
Comparison 132SMT Baseline PMA- vs SMT Final J PMA-PDFSVGPDFSVGPDFSVG
Comparison 133SMT B Final PMA+ vs SMT A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 134SMT C Final PMA+ vs SMT A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 135SMT D Final PMA+ vs SMT A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 136SMT E Final PMA+ vs SMT A Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 137SMT G Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 138SMT H Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 139SMT I Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 140SMT J Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 141SMT D Final PMA+ vs SMT B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 142SMT E Final PMA+ vs SMT B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 143SMT G Final PMA+ vs SMT B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 144SMT I Final PMA+ vs SMT B Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 145SMT D Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 146SMT E Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 147SMT G Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 148SMT I Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 149SMT D Final PMA+ vs SMT E Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 150SMT H Final PMA+ vs SMT J Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 151SMT J Final PMA+ vs SMT G Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 152SMT I Final PMA+ vs SMT G Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 153SMT B Final PMA+ vs SMT C Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 154SMT A Final PMA+ vs SMT F Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 155SMT A Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT D Final PMA+ vs SMT E Final PMA+ vs SMT F Final PMA+ vs SMT G Final PMA+ vs SMT H Final PMA+ vs SMT I Final PMA+ vs SMT J Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 156SMT A Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT D Final PMA+ vs SMT E Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 157SMT F Final PMA+ vs SMT B Final PMA+ vs SMT C Final PMA+ vs SMT G Final PMA+ vs SMT I Final PMA+PDFSVGPDFSVGPDFSVG
Comparison 158SMT B Final PMA- vs SMT A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 159SMT C Final PMA- vs SMT A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 160SMT D Final PMA- vs SMT A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 161SMT E Final PMA- vs SMT A Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 162SMT G Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 163SMT H Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 164SMT I Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 165SMT J Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 166SMT D Final PMA- vs SMT B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 167SMT E Final PMA- vs SMT B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 168SMT G Final PMA- vs SMT B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 169SMT I Final PMA- vs SMT B Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 170SMT D Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 171SMT E Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 172SMT G Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 173SMT I Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 174SMT D Final PMA- vs SMT E Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 175SMT H Final PMA- vs SMT J Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 176SMT J Final PMA- vs SMT G Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 177SMT I Final PMA- vs SMT G Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 178SMT B Final PMA- vs SMT C Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 179SMT A Final PMA- vs SMT F Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 180SMT A Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT D Final PMA- vs SMT E Final PMA- vs SMT F Final PMA- vs SMT G Final PMA- vs SMT H Final PMA- vs SMT I Final PMA- vs SMT J Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 181SMT A Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT D Final PMA- vs SMT E Final PMA-PDFSVGPDFSVGPDFSVG
Comparison 182SMT F Final PMA- vs SMT B Final PMA- vs SMT C Final PMA- vs SMT G Final PMA- vs SMT I Final PMA-PDFSVGPDFSVGPDFSVG
 
 

XII. Analysis - Network Association

To analyze the co-occurrence or co-exclusion between microbial species among different samples, network correlation analysis tools are usually used for this purpose. However, microbiome count data are compositional. If count data are normalized to the total number of counts in the sample, the data become not independent and traditional statistical metrics (e.g., correlation) for the detection of specie-species relationships can lead to spurious results. In addition, sequencing-based studies typically measure hundreds of OTUs (species) on few samples; thus, inference of OTU-OTU association networks is severely under-powered. We provide the network association result with SparCC (Sparse Correlations for Compositional data)(Friedman & Alm 2012), which is a method for inferring correlations from compositional data. SparCC estimates the linear Pearson correlations between the log-transformed components.


References:

Friedman J, Alm EJ. Inferring correlation networks from genomic survey data. PLoS Comput Biol. 2012;8(9):e1002687. doi: 10.1371/journal.pcbi.1002687. Epub 2012 Sep 20. PMID: 23028285; PMCID: PMC3447976.

 

Association Network Inference by SparCC

 
 

 
 

XIII. Disclaimer

The results of this analysis are for research purpose only. They are not intended to diagnose, treat, cure, or prevent any disease. Forsyth and FOMC are not responsible for use of information provided in this report outside the research area.

 
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