The ADA Forsyth Insitute's Oral Microbiome Core (FOMC) is offering Next Generation Sequencing (NGS) and comprehensive data analyses. We also provide interpretation for 16S rRNA gene amplicon sequences and other big data sequence applications. The primary focus of the FOMC involves the microbial analysis of samples derived from the human oral cavity, however analyses of samples from all human, animal, and environmental sites are also available.

Analyses of previously obtained sequences are also offered. Many investigators are familiar with the Human Oral Microbe Identification using Next Generation Sequencing (HOMINGS) as well as its predecessor the Human Oral Microbe Identification Microarray (HOMIM) for rapid 16S rDNA analyses of oral clinical samples. We continue in that tradition using state-of-the-art bioinformatic methodology, which will provide the best possible taxa identification.

Dr. Bruce Paster (, an internationally known oral microbiome researcher and the formal director of FOMC, provides research consultation and result interpretations to the researchers. Dr. George Chen (, director of Forsyth Bioinformatics Core, has recently taken the helm for FOMC as the new director. He is a well-known bioinformatic specialist in oral microbiome research and has many years of NGS sequencing, bioinformatics and microbiomic research expereince.

Services that we offer:

Next Generation Sequencing
We can sequence 16S rRNA gene amplicon V1V3 and V3V4 regions. We can also sequence meta-genomes. Professional sequence data analysis included.
Data Analysis: 16S rRNA NGS data
We use advanced analysis pipeline to analyze 16S rRNA gene amplicon data, including sequence quality control, read denoising, taxonomy assignment and downstream diversity, differential abundance analyses.
Data Analysis: Meta-genomic/transcriptomic NGS data
We use robust open-source meta-genomic and meta-transcriptomic data analysis and visualization software packages, such as HUMAnN and Kraken to taxonomically and functionally profile the meta-genomic or meta-transcriptomic NGS data.
Bioinformatics Data Analysis
>We provide professional analyses for other types of bioinformatics data. Please visit Forsyth Bioinformatics Core website for more detail.
Professional data interpretation
We provide professional data interpretation for the analytical results generated from the NGS data. We also provide consultation for microbiome research, including experimental design and data analysis approach.
Assist in writing reports, grants, and manuscripts
The results generated from our pipelines are publication-ready quality. We can also customize the results to suit your needs for your reports, grant applications and manuscripts.
We attended the 2021 IADR Annual Virtual Meeting July 21-24, 2021. We also made our presence at the FOMC Virtual Booth, to answer customers' questions and discussed the projects. Our booth chat hours were 10:00 am, 12:30 pm, and 3:00 pm US Eastern Time (GMT-4), each day between July 21-23, and 10:00 am on July 24th. Below is an introduction video presented by Dr. Bruce Paster. Hope you find the video useful!

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Page last updated: February 22, 2024 08:25:51